Patents Represented by Attorney Edward A. Conroy, Jr.

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  • Method for treating anxiety in mammals
    Patent number: 4117130
    Abstract: This disclosure describes compositions of matter useful as anxiolytic agents and the method of meliorating anxiety in mammals therewith; the active ingredients of said compositions of matter being certain substituted 6-phenyl-1,2,4-triazolo[4,3-b]pyridazines or the pharmacologically acceptable acid-addition salts thereof.
    Type: Grant
    Filed: November 21, 1977
    Date of Patent: September 26, 1978
    Assignee: American Cyanamid Company
    Inventors: George Rodger Allen, Jr., John William Hanifin, Jr., Daniel Bryan Moran, Jay Donald Albright
  • 4-(Monoalkylamino)benzonitriles useful as anti-atherosclerotic agents
    Patent number: 4117158
    Abstract: This disclosure describes novel 4-(monoalkylamino)benzonitriles and 5-[4-(monoalkylamino)phenyl]tetrazoles and homologs thereof useful as hypolipidemic and anti-atherosclerotic agents.
    Type: Grant
    Filed: September 27, 1977
    Date of Patent: September 26, 1978
    Assignee: American Cyanamid Company
    Inventor: Robert Gordon Shepherd
  • Acyl derivatives of antibiotic BM123.gamma.
    Patent number: 4112219
    Abstract: This disclosure describes a novel series of potent antibacterial agents derived by acylation of antibiotic BM123.gamma. with N-acyloxysuccinimide derivatives.
    Type: Grant
    Filed: July 13, 1977
    Date of Patent: September 5, 1978
    Assignee: American Cyanamid Company
    Inventor: Joseph John Hlavka
  • 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazine hypotensive agents
    Patent number: 4112095
    Abstract: This disclosure describes novel substituted 6-phenyl-1,2,4-triazolo[4,3-b]pyridazines useful as hypotensive agents.
    Type: Grant
    Filed: July 29, 1977
    Date of Patent: September 5, 1978
    Assignee: American Cyanamid Company
    Inventors: George Rodger Allen, Jr., John William Hanifin, Jr., Daniel Bryan Moran, Jay Donald Albright
  • Novel benzylideneaminoguanidines
    Patent number: 4107326
    Abstract: This disclosure describes novel substituted benzylideneaminoguanidines useful as anti-hypertensive agents and as diuretics.
    Type: Grant
    Filed: May 6, 1977
    Date of Patent: August 15, 1978
    Assignee: American Cyanamid Company
    Inventors: Leon Goldman, Yang-i Lin, Joseph William Marsico, Jr.
  • Substituted imidazo[1,2-d]-as-triazines
    Patent number: 4107309
    Abstract: This disclosure describes novel 5-substituted imidazo[1,2-d]-as-triazines useful as anti-asthmatic agents and as inhibitors of the enzyme cyclic-AMP phosphodiesterase.
    Type: Grant
    Filed: May 23, 1977
    Date of Patent: August 15, 1978
    Assignee: American Cyanamid Company
    Inventors: Rolf Paul, Judith Menschik
  • Substituted imidazo [1,2-d]-as-triazines
    Patent number: 4096257
    Abstract: This disclosure describes 5-n-propyl-imidazo[1,2-d]-as-triazin-8(7H)-one and 5-phenyl-imidazo[1,2-d]-as-triazin-8(7H)-one which are useful as anti-asthmatic agents and as inhibitors of the enzyme cyclic-AMP phosphodiesterase.
    Type: Grant
    Filed: May 23, 1977
    Date of Patent: June 20, 1978
    Assignee: American Cyanamid Company
    Inventors: Judith Menschik, Rolf Paul
  • Hypotensive alkyl-3-[6-(aryl)-3-pyridazinyl]-carbazates
    Patent number: 4092311
    Abstract: This disclosure describes novel alkyl 3-[6-(aryl)-3-pyridazinyl]-carbazates useful as hypotensive agents in mammals. SPCROSS REFERENCE TO RELATED APPLICATIONSThis application is a continuation of our copending application Ser. No. 692,254, filed June 3, 1976 now abandoned, which in turn is a continuation-in-part of our abandoned application Ser. No. 552,024, filed Feb. 24, 1975 now abandoned.
    Type: Grant
    Filed: August 24, 1977
    Date of Patent: May 30, 1978
    Assignee: American Cyanamid Company
    Inventors: John William Hanifin, Jr., Daniel Bryan Moran, Jay Donald Albright, George Rodger Allen, Jr.
  • Novel 1,2,3,4-tetrahydro-4-oxo-(-oxy-)-1-naphthylamines and method of preparation thereof
    Patent number: 4091018
    Abstract: This disclosure describes 1,2,3,4-tetrahydro-4-oxo-(oxy)-1-naphthylamine and novel derivatives thereof and methods of preparation of said compounds. These novel compounds are useful and valuable intermediates for the preparation of 1,2,3,4-tetrahydro-4-oxo(oxy)-1-naphthylurea and thiourea compounds and certain derivatives thereof which are animal growth promoters.
    Type: Grant
    Filed: June 8, 1977
    Date of Patent: May 23, 1978
    Assignee: American Cyanamid Company
    Inventor: Goro Asato
  • Synthesis of 1,2,3,4-tetrahydro-4-oxo-[or oxy-]-1-naphthylureas as novel growth-promoting compounds for animals
    Patent number: 4089976
    Abstract: This invention relates to novel 1,2,3,4-tetrahydro-4-oxo-[-oxy-]-1-naphthylurea compounds and their derivatives. This invention also relates to method for the preparation of said compounds. This invention further relates to methods for the use of said tetrahydro-4-oxo-[oxy-]-1-naphthylurea compounds as animal growth regulators.
    Type: Grant
    Filed: August 12, 1976
    Date of Patent: May 16, 1978
    Assignee: American Cyanamid Company
    Inventor: Goro Asato
  • Process for the preparation of cis-5,6-dimethoxy-2-methyl-3-[2-(4-phenyl-1-piperazinyl)-ethyl]indoline
    Patent number: 4089853
    Abstract: There is provided a process for the manufacture of pure cis isomer of 5,6-dimethoxy-2-methyl-3-[2-(4-phenyl-1-piperazinyl)ethyl]indoline by the ionic hydrogenation of 5,6-dimethoxy-2-methyl-3-[2-(4-phenyl-1-piperazinyl)ethyl]indole.
    Type: Grant
    Filed: February 9, 1977
    Date of Patent: May 16, 1978
    Assignee: American Cyanamid Company
    Inventor: Anthony Edward Lanzilotti
  • Compositions containing benzoylacetonitrile and method of use to treat inflammation
    Patent number: 4083993
    Abstract: This disclosure describes compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease, and the method of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the active ingredients of said compositions of matter being benzoylacetonitrile, o-fluorobenzoylacetonitrile, m-fluorobenzoylacetonitrile, p-fluorobenzoylacetonitrile, or mixtures thereof.
    Type: Grant
    Filed: June 17, 1977
    Date of Patent: April 11, 1978
    Assignee: American Cyanamid Co.
    Inventors: Adolph Edward Sloboda, John William Hanifin
  • 3-Alkyl-2-(6-carboxyhexyl) cyclopentanones and esters and salts thereof
    Patent number: 4074056
    Abstract: This disclosure describes compounds of the class of substituted 9-oxoprostanoic acids and the esters and cationic salts thereof, useful as antimicrobial agents, hypotensive agents, anti-ulcer agents, or as intermediates, and novel processes for preparing the same.
    Type: Grant
    Filed: January 4, 1977
    Date of Patent: February 14, 1978
    Assignee: American Cyanamid Company
    Inventors: Robert E. Schaub, Karel F. Bernady, Martin J. Weiss
  • Diaminoalditols useful in the preparation of antibacterial antibiotics AM31.alpha., AM31.beta., and AM31.gamma.
    Patent number: 4071560
    Abstract: This disclosure describes a novel class of antibiotics, three of which have been designated AM31.alpha., AM31.beta., and AM31.gamma. and are produced in a microbiological fermentation under controlled conditions using a new strain of Streptoverticillium netropsis.
    Type: Grant
    Filed: March 8, 1977
    Date of Patent: January 31, 1978
    Assignee: American Cyanamid Company
    Inventors: Jane Parsons Kirby, Donald Bruce Borders
  • Compositions containing dioctyl calcium sulfosuccinate
    Patent number: 4070456
    Abstract: Compositions comprising dioctyl calcium sulfosuccinate in a mixture of non-aqueous, i.e. oil, solvents are disclosed as being resistant to crystallization at low temperatures. Dosage units comprising gelatin capsules containing said compositions are also disclosed. The compositions of this invention are useful as fecal softeners.
    Type: Grant
    Filed: April 5, 1976
    Date of Patent: January 24, 1978
    Assignee: American Cyanamid Company
    Inventors: John Kazan, Robert Arnold Nash
  • Process for producing antibacterial antibiotics AM31.alpha., AM31.beta., and AM31.gamma. with Streptoverticillium netropsis
    Patent number: 4064012
    Abstract: This disclosure describes a novel class of antibiotics, three of which have been designated AM31.alpha., AM31.beta., and AM31.gamma. and are produced in a microbiological fermentation under controlled conditions using a new strain of Streptoverticillium netropsis.
    Type: Grant
    Filed: March 8, 1977
    Date of Patent: December 20, 1977
    Assignee: American Cyanamid Company
    Inventors: Jane Parsons Kirby, Donald Bruce Borders
  • Method of treating anxiety and compositions therefor
    Patent number: 4062958
    Abstract: This disclosure describes compositions of matter useful as anxiolytic agents and the method of meliorating anxiety in mammals therewith, the active ingredient of said compositions of matter being 3-methyl-6-phenyl-1,2,4-triazolo[4,3-b]pyridazine or a pharmacologically acceptable acid-addition salt thereof.
    Type: Grant
    Filed: September 22, 1976
    Date of Patent: December 13, 1977
    Assignee: American Cyanamid Company
    Inventors: George Rodger Allen, Jr., John William Hanifin, Jr., Daniel Bryan Moran, Jay Donald Albright
  • Ureidotetralin compounds
    Patent number: 4062856
    Abstract: This invention relates to ureidotetralin compounds and derivatives and selected enantiomers thereof. This invention also relates to methods for the preparation of said compounds which are useful as animal growth regulators and/or herbicidal agents.
    Type: Grant
    Filed: September 9, 1976
    Date of Patent: December 13, 1977
    Assignee: American Cyanamid Co.
    Inventors: Larry Dean Spicer, Joseph Michael Pensack, Robert Daniel Wilbur, Gary Michael Demkovich
  • Substituted tetrahydroiminobenzo(b)thien-4-ylureas as novel growth promoting compounds for animals
    Patent number: 4060627
    Abstract: This disclosure describes novel 4,5,6,7-tetrahydro-7-iminobenzo[b]thien-4-ylureas, methods of preparation thereof, and methods of use of said compounds for enhancing feed efficiency and for promoting the growth rate of veterinary homothermic animals.
    Type: Grant
    Filed: October 14, 1975
    Date of Patent: November 29, 1977
    Assignee: American Cyanamid Company
    Inventors: Goro Asato, Terence James Bentley
  • 1-Benzoyl-3-(4,5,6,7-tetrahydrobenzo [b]thien-4-yl)ureas and 1-benzoyl-3-(4,5,6,7-tetrahydro-7-oxobenzo [b]thien-4-yl)ureas, novel intermediates for the preparation of animal growth promoting agents
    Patent number: 4053484
    Abstract: This invention relates to 1-benzoyl-3-(4,5,6,7-tetrahydrobenzo[b]thien-4-yl)urea, 1-benzoyl-3-(4,5,6,7-tetrahydro-7-oxobenzo[b]thien-4-yl)urea, and derivatives thereof and a method for the preparation of said compounds and substituted derivatives. Both of the above referred-to compounds are novel and useful intermediates for the preparation of the corresponding tetrahydrobenzo[b]thien-4-ylurea and tetrahydro-7-oxobenzo[b]thien-4-ylurea, respectively. The latter compounds and certain derivatives thereof are animal growth promoting agents.
    Type: Grant
    Filed: June 1, 1976
    Date of Patent: October 11, 1977
    Assignee: American Cyanamid Company
    Inventor: Goro Asato