Patents Represented by Attorney Edward A. Conroy, Jr.

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  • Pyrido[1',2':4,5][1,4]oxazino[2,3-b]quinoxalines and pyrrolo[1',2':4,5][1,4]oxazino[2,3-b]quinoxalines
    Patent number: 4200748
    Abstract: This disclosure describes substituted 2,3,3a,4-tetrahydro-1H-pyrrolo[1',2':4,5][1,4]oxazino[2,3-b]quinoxalines and 1,2,3,4,4a,5-hexahydropyrido[1',2':4,5][1,4]oxazino[2,3-b]quinoxalines which possess anxioyltic activity.
    Type: Grant
    Filed: January 22, 1979
    Date of Patent: April 29, 1980
    Assignee: American Cyanamid Company
    Inventors: William B. Wright, Jr., Andrew S. Tomcufcik
  • 4-(Monoalkylamino)phenyl carbinols and ester derivatives
    Patent number: 4198522
    Abstract: This disclosure describes 4-monoalkylaminophenyl carbinols (primary, secondary, and tertiary alcohols) and with derivatives and salts thereof useful as hypolipidemic and anti-atherosclerotic agents.
    Type: Grant
    Filed: September 27, 1977
    Date of Patent: April 15, 1980
    Assignee: American Cyanamid Company
    Inventor: Robert G. Shepherd
  • 1,4-Bis(substituted-amino)-5,8-dihydroxyanthraquinones and leuco bases thereof
    Patent number: 4197249
    Abstract: This disclosure describes symmetrical 1,4-bis(substituted-amino)-5,8-dihydroxyanthraquinones useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.
    Type: Grant
    Filed: July 11, 1978
    Date of Patent: April 8, 1980
    Assignee: American Cyanamid Company
    Inventors: Keith C. Murdock, Frederick E. Durr
  • Thiophenepropionitriles
    Patent number: 4197310
    Abstract: This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the novel active ingredients of said compositions of matter being certain substituted cis-2-[2(or 3)-thenoyl]-3-hydroxy-2-alkenenitriles and/or the pharmacologically acceptable cationic salts thereof.
    Type: Grant
    Filed: April 30, 1979
    Date of Patent: April 8, 1980
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Antibiotic BM123-dioctyl sulfosuccinate complexes
    Patent number: 4196200
    Abstract: This disclosure describes reversible complexes of antibiotic trans-BM123.gamma. with a dioctyl sulfosuccinate salt and a process for preparing same. The complexes are useful as animal feed supplements which significantly enhance the growth rate of animals and poultry.
    Type: Grant
    Filed: February 2, 1978
    Date of Patent: April 1, 1980
    Assignee: American Cyanamid Company
    Inventors: Martin Tobkes, Murray Dann
  • Certain pyridyl esters of 4-(monoalkylamino) benzoic hydroxyalkanoic acids
    Patent number: 4196208
    Abstract: This disclosure describes esters of 4-(monoalkylamino)benzoic acids with hydroxyalkanoic acids and derivatives, phenols, or 3-pyridinols useful as hypolipidemic agents.
    Type: Grant
    Filed: December 19, 1977
    Date of Patent: April 1, 1980
    Assignee: American Cyanamid Company
    Inventor: Robert G. Shepherd
  • Antibiotic BM123-alkyl sulfate complexes
    Patent number: 4196198
    Abstract: This disclosure describes reversible complexes of antibiotic trans-BM123.gamma. with an alkali metal alkyl sulfate and a process for preparing same. The complexes are useful as animal feed supplements which significantly enhance the growth rate of animals and poultry.
    Type: Grant
    Filed: February 2, 1978
    Date of Patent: April 1, 1980
    Assignee: American Cyanamid Company
    Inventors: Martin Tobkes, Murray Dann
  • Antibiotic BM123 syntan complexes
    Patent number: 4196199
    Abstract: This disclosure describes reversible complexes of antibiotic trans-BM123.gamma. with a synthetic tanning agent and a process for preparing same. The complexes are useful as animal feed supplements which significantly enhance the growth rate of animals and poultry.
    Type: Grant
    Filed: February 2, 1978
    Date of Patent: April 1, 1980
    Assignee: American Cyanamid Company
    Inventors: Martin Tobkes, Murray Dann
  • 5H-Pyrrolo[2,1-c][1,4]benzodiazepine derivatives
    Patent number: 4192803
    Abstract: This disclosure describes substituted 11-piperazinyl-5H-pyrrolo[2,1-c][1,4]benzodiazepines useful as anti-psychotic or neuroleptic agents.
    Type: Grant
    Filed: September 15, 1978
    Date of Patent: March 11, 1980
    Assignee: American Cyanamid Company
    Inventors: William B. Wright, Jr., Robert A. Hardy, Jr.
  • Process of producing antibiotic BL580.DELTA. with Streptomyces hygroscopicus
    Patent number: 4189537
    Abstract: This disclosure describes a new antibiotic designated BL580.DELTA. produced in a microbiological fermentation under controlled conditions using a new strain of Streptomyces hygroscopicus and mutants thereof. This new antibiotic is an active anticoccidial agent.
    Type: Grant
    Filed: November 20, 1978
    Date of Patent: February 19, 1980
    Assignee: American Cyanamid Company
    Inventors: John H. E. J. Martin, Martin R. Hertz
  • .beta.-oxo-3-thiophene propionitrile and .beta.-amino-2-(3)-thiophene acrylonitriles
    Patent number: 4189436
    Abstract: This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the active ingredients of said compositions of matter being .beta.-oxo-3-thiophenepropionitrile, .beta.-amino-2-thiopheneacrylonitrile, and/or .beta.-amino-3-thiopheneacrylonitrile.
    Type: Grant
    Filed: August 24, 1978
    Date of Patent: February 19, 1980
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, David N. Ridge
  • Method of treating arthritic disease
    Patent number: 4189497
    Abstract: This disclosure describes compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease, and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the active ingredient of said compositions of matter being .beta.-oxo-2-thiophenepropionitrile or the pharmaceutically acceptable cationic salts thereof.
    Type: Grant
    Filed: August 22, 1978
    Date of Patent: February 19, 1980
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Adolph E. Sloboda
  • Novel dihydrobenzanthracene derivatives
    Patent number: 4187373
    Abstract: This disclosure describes benzanthracene-5,12(or 7,12)-dicarboxaldehyde-bis-hydrazones and the 5,12(or 7,12)-dihydrobenzanthracene-5,12(or 7,12)-dicarboxaldehyde-bis-hydrazones useful as antibacterial agents, for inhibiting the growth of transplanted mouse tumors, and for inducing the regression and/or pallation of leukemia and related cancers.
    Type: Grant
    Filed: October 2, 1978
    Date of Patent: February 5, 1980
    Assignee: American Cyanamid Company
    Inventors: Ralph G. Child, Stanley A. Lang, Jr., Ving J. Lee, Yang-i Lin
  • Antilipidemic para-[aryl(alkyl or alkenyl)amino]-benzoic acid derivatives
    Patent number: 4185115
    Abstract: Novel para-[aryl(alkyl or alkenyl)amino]benzoic acids, esters, pharmaceutically acceptable salts and pharmaceutical compositions thereof and a method of lowering serum lipid levels in mammals therewith.
    Type: Grant
    Filed: March 12, 1975
    Date of Patent: January 22, 1980
    Assignee: American Cyanamid Company
    Inventors: Jay D. Albright, Thomas G. Miner, Robert G. Shepherd
  • Method of treating lipidemia with aryloxyalkylaminobenzoic acids and esters
    Patent number: 4182776
    Abstract: Aryloxyalkylaminobenzoic acids and esters as hypolipemic compounds.
    Type: Grant
    Filed: March 30, 1978
    Date of Patent: January 8, 1980
    Assignee: American Cyanamid Company
    Inventors: Jay D. Albright, Thomas G. Miner, Robert G. Shepherd
  • 2-Benzoyl-3-alkoxy-2-alkenonitriles
    Patent number: 4181677
    Abstract: This disclosure describes novel substituted 2-benzoyl-3-alkoxy-2-alkenonitriles and substituted 2-benzoyl-3-amino-2-alkenonitriles which are useful as intermediates for the preparation of certain substituted cis-2-benzoyl-3-hydroxy-2-alkenonitriles which possess anti-inflammatory activity.
    Type: Grant
    Filed: December 13, 1978
    Date of Patent: January 1, 1980
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Pyrazolo[1,5-a]pyrimidines and imidazo-[1,5-a]pyrimidines
    Patent number: 4178449
    Abstract: This disclosure describes substituted pyrazolo[1,5-a]pyrimidines and imidazo[1,5-a]pyrimidines which possess anxiolytic activity.
    Type: Grant
    Filed: December 15, 1978
    Date of Patent: December 11, 1979
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Jay D. Albright
  • Cis-2-benzoyl-3-hydroxy-2-alkenonitriles as anti-inflammatory agents
    Patent number: 4173650
    Abstract: This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the novel active ingredients of said compositions of matter being certain substituted cis-2-benozyl-3-hydroxy-2-alkenonitriles and/or the pharmacologically acceptable cationic salts thereof.
    Type: Grant
    Filed: November 3, 1978
    Date of Patent: November 6, 1979
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Compositions containing cis-2-benzoyl-3-hydroxy-crotononitrile used to treat inflammation and joint deterioration
    Patent number: 4170656
    Abstract: This disclosure describes compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease, and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the active ingredients of said composition of matter being certain cis-2-benzoyl-3-hydroxy-2-alkenonitriles and/or the pharmacologically acceptable cationic salts thereof.
    Type: Grant
    Filed: March 31, 1978
    Date of Patent: October 9, 1979
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Substituted thieno-benzodiazepines
    Patent number: 4168269
    Abstract: This disclosure describes substituted 9,10-dihydro-4H-thieno[3,4-b] [1,5]benzodiazepines which possess analgesic activity.
    Type: Grant
    Filed: April 12, 1978
    Date of Patent: September 18, 1979
    Assignee: American Cyanamid Company
    Inventors: Herbert J. Brabander, Joseph W. Epstein, Lantz S. Crawley