Abstract: Provided is an input/output line sharing apparatus of a semiconductor memory device. In this apparatus, a global input/output line is shared by a data line signal and a test mode signal, and an input/output line between test mode signals is shared. The apparatus comprises a global input/output line, a first control signal generating unit configured to generate a test mode control signal from a test mode register set signal, a multiplexer configured to output a signal selected from a data line signal and a test mode signal to the global input/output line in response to the test mode control signal, and a latch unit configured to store the test mode signal outputted from the global input/output line in response to the test mode control signal.

Abstract: An input/output byte control device using a nonvolatile ferroelectric register can maintain compatibility with various memories by selectively controlling bytes of input/output data. Since bytes of input/output data are selectively activated, the compatibility can be maintained with SRAM (Static Random Access Memory) having wide bytes and flash memory having fixed input/output bytes. Additionally, programs can be changed in a software system using a nonvolatile ferroelectric register.

Abstract: Disclosed are 2-(1-isopropoxycarbonyloxy-2-methylpropyl)-7,8-dimethoxy-4(5H), 10-dioxo-2H-1,2,3-triazolo[4,5-c][1]benzazepine, which has been rendered amorphous and possesses improved absorption and dissoluvability, and a pharmaceutical composition comprising the same. Also disclosed are processes for producing 2-(1-isopropoxycarbonyloxy-2-methylpropyl)-7,8-dimethoxy-4(5H), 10-dioxo-2H-1,2,3-triazolo[4,5-c][1]benzazepine, which has been rendered amorphous, and a pharmaceutical composition comprising the same.

Abstract: A device for use with a gripper is provided. A cartridge is provided that defines a plurality of cavities. A plurality of penetrating members are at least partially contained in the cavities of the cartridge. The penetrating members are slidably movable to extend outward from the cartridge to penetrate tissue. Each cavity has a longitudinal opening that provides access to an elongate portion of the penetrating member. A sterility barrier is coupled to the cartridge. The sterility barrier covers a plurality of the longitudinal openings. The sterility barrier is configured to be moved so that the elongate portion is accessed by the gripper without touching the barrier.

Abstract: In an underwater acoustic bearing sensor, the vector sensor, heading sensor, and pitch and roll sensor are held in a common mounting ring to ensure that their coordinate systems are collinear. The vector sensor includes x, y, and z accelerometers mounted in the ring and a hydrophone that can be mounted independently.

Abstract: A transistor and a method for manufacturing the same are disclosed. One cell transistor having silicon-insulator-silicon (“SIS”) structure and two cell transistors having silicon-oxide-nitride-oxide-silicon (“SONOS”) structure constitute the transistor of the present invention which can store 2 bits. The cell transistor having SIS structure and the cell transistors having SONOS structure share one common gate electrode so that the transistor of the present invention requires only one voltage generation and control circuit.

Abstract: Degradable polyacetal polymers and functionalized degradable polyacetal polymers have properties favorable for use in pharmaceutical and biomedical applications. The degradable polyacetal polymers are relatively stable at physiological pH with favorable biodistribution profiles, and degrade readily in low pH conditions. Conjugates of the polymers with drugs, especially anticancer drugs, and methods of treatment of cancer.

Abstract: The present invention discloses improved method for manufacturing semiconductor device wherein a barrier layer is formed by thermally treating a hard mask polysilicon layer for protecting the sacrificial oxide film and the hard mask polysilicon film from damages.

Abstract: An apparatus is provided for testing fluid samples includes a sensor, which can be light source, directed to a flow cell and a photo sensor for detecting a light beam reflected from the flow cell. The photo sensor monitors the fluid in the flow cell by sensing the reflected light beam from the flow cell, thereby monitoring the test.

Abstract: The present invention relates to methods for identifying compounds that modulate enzymatic activity by contacting covalently bonded PTP-extender complexes or modified covalently bonded PTP-extender complexes with ligand candidates.

Abstract: The present invention is a recombinant vector encoding and expressing at least three or more costimulatory molecules. The recombinant vector may additionally contain a gene encoding one or more target antigens or immunological epitope thereof. The synergistic effect of these costimulatory molecules on the enhanced activation of T cells is demonstrated. The degree of T-cell activation using recombinant vectors containing genes encoding three costimulatory molecules was far greater than the sum of recombinant vector constructs containing one costimulatory molecule and greater than the use of two costimulatory molecules. Results employing the triple costimulatory vectors were most dramatic under conditions of either low levels of first signal or low stimulator to T-cell ratios. This phenomenon was observed with both isolated CD4+ and CD8+ T cells.

Abstract: A non-volatile ferroelectric memory device having differential datacomprises a plurality of cell array blocks and a data buffer unit. Each of the plurality of cell array blocks includes cell arrays and sense amplifiers. The cell array has a hierarchical bit line architecture and are divided into top and bottom groups where differential data are stored in a plurality of unit cells corresponding to differential main bit lines of the divided cell arrays. The sense amplifiers are positioned between the divided cell array groups for sensing the differential data. The data buffer unit temporarily stores a read data sensed by the sense amplifier and a write data received through a data I/O port.

Abstract: Disclosed is a non-volatile ferroelectric memory device having differential data, the device including: a plurality of cell array block groups having a hierarchy bit line structure and storing differential data; a common data bus being shared by a plurality of the cell array block groups, and transferring sensing voltages induced by the differential data; a column selection control unit selectively applying to the common data bus the induced sensing voltages of two main bit lines of the cell array block group according to the differential data; and a sense amp unit receiving the sensing voltages through the common data bus, comparing two sensing voltages induced by the differential data, and sensing the cell data. Therefore, the non-volatile ferroelectric memory device of the invention is capable of sensing a cell data more stably, independent of external factors and the state of a cell, by simultaneously sensing the stored data (differential data) in two unit cells and detecting the cell data.

Abstract: A column selection signal generator of a semiconductor memory device is configured to maintain a predetermined pulse width of a column selection signal regardless of change in process and external conditions by selectively using a self-generated pulse signal and a pulse signal generated by an external clock signal. The column selection signal generator includes a command combination unit, a pulse generating unit, a comparison unit and a selection unit.

Abstract: A nonvolatile ferroelectric memory device comprises a cell array block, a sense amplifier unit, a main amplifier unit and a data bus unit. The ferroelectric sense amplifier effectively senses and amplifies cell data having a small voltage difference applied to a main bit line, thereby improving operation characteristics in a low voltage. Also, a sensing voltage of the main bit line is lowered, thereby reducing a cross talk noise effect between main bit lines.

Abstract: The invention relates to a method for the enrichment or depletion of tumor cells from a body fluid, in which a cell separation medium of specific density is overlaid with the body fluid and is centrifuged. A kit suitable for this method is likewise provided.

Abstract: A nonvolatile ferroelectric memory device and a control method thereof are provided to control read/write operations of memory cell arrays whose channel resistance is differentiated depending on a polarity state of a ferroelectric material. In the device, data read from a memory cell are sensed and amplified through a sense amplifier, and the amplified data are stored in a register. Then, high data are written in all activated cells. Thereafter, new data applied from a data bus unit to a selected memory cell are written in response to an output signal from a column decoder, and data stored in the register are written-back in an unselected memory cell.

Abstract: Methods and systems for rapidly determining the level of platelet inhibition in whole blood, due to aspirin usage, with a single use arachidonic based assay device that can be stored at room temperature is provided. A lyophilized assay reagent that contains arachidonic acid at sufficient concentration to maximally activate platelets is utilized. An antioxidant within the same lyophilized assay reagent reduces the oxidation rate of arachidonic acid but does not interfere with platelet function. An oxygen absorber within the single use assay device packaging creates an inert environment within a short period of time after package is sealed. The assay device can have a housing with a plurality of channels and a common blood sample introduction port coupled to each of a channel of the plurality of channels. The assay device can also include a lyophilized assay reagent that contains arachidonic acid at sufficient concentration to maximally activate platelets.

Abstract: The invention concerns the identification of protein kinase inhibitors that preferentially bind to the inactive conformation of a target protein kinase. The inhibitors are identified by locking the target protein kinase in an inactive conformation, and using a covalent tethering approach to identify inhibitors preferentially targeting the inactive conformation.

Abstract: The present invention is directed to novel polypeptides having homology to members of the tumor necrosis factor receptor family and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.