Patents Represented by Attorney, Agent or Law Firm Howson and Howson
  • Patent number: 6736939
    Abstract: In a shoe press belt, in which the nip zone is narrower than the shoe width, the shearing force which normally acts on the belt at the outer boundary of the nip zone is made either weak or non-existent by forming the outer portions of the belt of less hardness than the inner, or central, portion of the belt, so that the less hard portions can be positioned directly opposite the outer boundaries of the nip zone. Alternatively, the outer portions of the belt can be made thinner than the central portion of the belt and the thinner portions positioned directly opposite to the nip zone boundaries. The shearing force applied to the belt at the nip ends of the roll is reduced or eliminated, cracking resulting from the shear force is reduced or avoided, and a belt having improved durability results.
    Type: Grant
    Filed: July 29, 2002
    Date of Patent: May 18, 2004
    Assignee: Ichikawa Co., Ltd.
    Inventor: Kazumasa Watanabe
  • Patent number: 6733409
    Abstract: A guide for a chain, or similar endless, flexible, power transmission device, is composed of a molded guide body, and a reinforcing plate fitting into a slot in the guide body. A nearly circular, but slightly elongated, mounting hole in the guide body is elongated in the front-to-back direction of the guide. The elongated mounting hole overlaps a circular mounting hole in the reinforcing plate, and allows relative adjustment of the positions of the holes so that the guide can be more easily mounted on an inner wall of an engine by a bolt or pin which extends through both mounting holes.
    Type: Grant
    Filed: September 27, 2002
    Date of Patent: May 11, 2004
    Assignee: Tsubakimoto Chain Co.
    Inventor: Masahiko Konno
  • Patent number: 6733410
    Abstract: A wear-elongation resistant silent chain includes guide link rows and articular link rows articulately connected together in an alternate fashion along the length of the chain by connecting pins inserted through respective pin holes of guide plates, guide link plates and articular link plates, with guide plate retainers secured to respective both ends of the connecting pins so as to keep the guide plates in position against removal from the connecting plates. The guide link plate and the articular link plates have different thicknesses so dimensioned as to balance the tensile strength of the guide link plate in one guide link row and the tensile strength of the articular link plates in the adjacent articular link row connected together by one of the connecting pins, thereby suppressing bending of the connecting pin. By thus suppressing the bending of connecting pin, wear elongation of the chain is prevented from occurring during power transmitting operation of the chain.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: May 11, 2004
    Assignee: Tsubakimoto Chain Co.
    Inventor: Toyonaga Saito
  • Patent number: 6722308
    Abstract: A handbell having an improved clapper assembly. The handbell includes a bell body in which the clapper assembly is mounted, and the clapper assembly has a compact construction including a yoke secured to a closed end of the bell body and a clapper mounted for swinging movement relative to the yoke along a path defining a forward swing direction and a back swing direction. The clapper has a head for striking the bell body and a pivot block pivotally mounted to the yoke. The pivot block carries at least one energy absorber that is engageable with the yoke during at least part of the swinging movement of the clapper for controlling the swinging movement of the clapper in one of the forward swing or back swing directions. Preferably, the clapper carries a pair of energy absorbers.
    Type: Grant
    Filed: April 1, 2003
    Date of Patent: April 20, 2004
    Assignee: Schulmerich Carillons, Inc.
    Inventor: Steven C. Moulden
  • Patent number: 6723183
    Abstract: The present invention relates to a non-brittle silicide target for forming a gate oxide film made of MSi0.8-1.2 (M: Zr, Hf), and provides a non-brittle silicide target suitable for forming a ZrO2.SiO2 film or HfO2.SiO2 film that can be used as a high dielectric gate insulating film having properties to substitute an SiO2 film.
    Type: Grant
    Filed: December 5, 2001
    Date of Patent: April 20, 2004
    Assignee: Nikko Materials Company, Limited
    Inventors: Kunihiro Oda, Hirohito Miyashita
  • Patent number: 6716318
    Abstract: A papermaking press felt having excellent rewetting suppression without impaired water-squeezing capability, comprises a base body, batt layers, and a rewetting prevention layer, integrated with one another by needle punching. The rewetting prevention layer has three dimensional passages comprising a verge opening, a wet paper web side opening and a roll side opening. The wet paper web side opening is larger than the roll side opening. Under nip pressure, water from the wet paper web moves into the roll surface side of the felt, passing through the passages in the rewetting prevention layer. Although a rewetting phenomenon tends to occur when the press felt is released from the nip pressure, movement of water through the passages back to the wet paper web side of the felt is suppressed since the roll side openings are narrower than the wet paper web side opening.
    Type: Grant
    Filed: September 9, 2002
    Date of Patent: April 6, 2004
    Assignee: Ichikawa Co., Ltd.
    Inventor: Kazumasa Watanabe
  • Patent number: 6716425
    Abstract: Methods for treating cancer in a mammalian patient having cancer and a functional immune system, and for preventing recurrences of cancer following completion of cancer therapy, are described. The methods involve administration of a course of therapy with modified TALL-104 cells, without requiring the co-administration of an immunosuppressive agent.
    Type: Grant
    Filed: June 20, 1997
    Date of Patent: April 6, 2004
    Assignee: The Wistar Institute of Anatomy and Biology
    Inventors: Daniela Santoli, Giovanni Rovera, Alessandra Cesano
  • Patent number: 6711903
    Abstract: A power plant generates electricity from carbonaceous material and fuel provided by a syngas plant such that clean electric power is generated and flue gas emissions are minimized. The syngas plant produces liquid fuel and unreacted syngas in a Fischer-Tropsch reactor, and the unreacted syngas is conducted to a combustion chamber of the power plant for use as a clean fuel moiety of the carbonaceous material burned in the combustion chamber. The unreacted syngas enables the electric power plant to operate below acceptable environmental limits in producing steam to generate electricity.
    Type: Grant
    Filed: February 19, 2003
    Date of Patent: March 30, 2004
    Inventor: John W. Rich, Jr.
  • Patent number: 6713478
    Abstract: This invention provides compounds of Formula (I): wherein R1 and R2 are independent substituents or are fused to form spirocyclic rings; R3, RC, and R4 are as defined herein; and R5 is a substituted benzene ring or a substituted five or six membered heterocyclic ring having in its backbone 1, 2, or 3 heteroatoms including O, S, SO, SO2 or NR6; or pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions and methods using the compounds as antagonists of the progesterone receptor.
    Type: Grant
    Filed: March 12, 2003
    Date of Patent: March 30, 2004
    Assignees: Wyeth, Ligand Pharmaceuticals, Inc.
    Inventors: Puwen Zhang, Eugene A. Terefenko, Andrew Fensome, Jay E. Wrobel, Horace Fletcher, III, Lin Zhi, Todd K. Jones, James P. Edwards, Christopher M. Tegley
  • Patent number: 6706526
    Abstract: A low formaldehyde containing aqueous blood diluent contains an effective amount of ethylenediamine tetraacetic acid, ethylenediamine tetraacetic acid derivative, or combinations thereof; an effective amount of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one; and an effective amount of 5-bromo-5-nitro-1,3-dioxane. Advantageously, less than about 1 parts per million of formaldehyde is produced in this multipurpose diluent. A method of analyzing a blood sample containing blood cells is conducted by forming a diluted blood sample by mixing a blood sample containing blood cells with this diluent and analyzing the diluted blood sample to determine a physical parameter of the blood cells.
    Type: Grant
    Filed: January 24, 2002
    Date of Patent: March 16, 2004
    Assignee: Coulter International Corp.
    Inventors: Russell F. Lang, Iris L. Payan, Barbara G. Murza, Luisa C. Oramas
  • Patent number: 6704978
    Abstract: The present invention relates to a method for guiding a flat web of material (1) in which the web of material (1) runs in an arrangement of rotating rollers at a web speed vF. The web of material is guided in its peripheral region via a spreader roll (2) which produces a tensile stress in the transverse direction, i.e. crosswise relative to the machine direction of the web of material (1), wherein this tension in the transverse direction is controlled by means of closed-loop control of the circumferential speed vR of the spreader roll (2) and/or by open-loop control of the cant angle &agr; and/or of the wrap angle &bgr; between the surface of the spreader roll (3) and the web of material (1) and wherein the circumferential speed vR is greater than the web speed vF.
    Type: Grant
    Filed: April 23, 2002
    Date of Patent: March 16, 2004
    Assignee: Trespaphan GmbH
    Inventors: Dieter Mathieu, Wolfgang Rasp
  • Patent number: 6699368
    Abstract: To improve the water squeezing function of a shoe press belt for papermaking, the wet web side layer of a main body of the belt is composed of a high molecular weight elastic material, and the wet web facing surface of the wet web side layer is made hydrophobic. Water, squeezed from the wet web under compression in a shoe press, and transferred to the surface of the wet web side layer of the belt through a felt, may be shaken off reliably before the belt is again subjected to compression.
    Type: Grant
    Filed: December 27, 2001
    Date of Patent: March 2, 2004
    Assignee: Ichikawa Co., Ltd.
    Inventors: Hirofumi Ishii, Nobuyuki Ito, Kazumasa Watanabe
  • Patent number: 6696243
    Abstract: A method of analyzing the concentration of soluble analyte in a sample involves performing a competition assay using a predetermined amount of formed bodies to which are attached at least one analyte, varying known concentrations of an unlabeled ligand that binds to analyte, and a known concentration of ligand labeled with a detectable marker. After analysis in a flow cytometer, the test sample and a plurality of control samples generate data on curves formed by plotting signal vs. concentration of labeled ligand in controls (first), and vs. concentration of total labeled and unlabeled ligand in test samples (second). The concentration of unlabeled ligand that bound to soluble analytes in test samples is determined by evaluating the difference between the concentration that corresponds with the intersection of these two curves and the constant labeled ligand concentration in the test samples.
    Type: Grant
    Filed: January 23, 2001
    Date of Patent: February 24, 2004
    Assignee: Coulter International Corp.
    Inventor: Olavi Siiman
  • Patent number: 6694589
    Abstract: A process for the handling of a tow of fibres during manufacture and subsequent processing prior to splicing is described. The process includes the step of applying a clip to the free end of the tow, prior to transport of the tow. The fibre is preferably a carbon fibre precursor, and the clip is preferably removed and the tow spliced prior to the steps of oxidation and carbonization to form the carbon fibre.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: February 24, 2004
    Assignee: Acordis UK Limited
    Inventor: David Mac Service
  • Patent number: 6693103
    Abstract: This invention provides compounds which are agonists and antagonists of the progesterone receptor having the general structure: wherein: R1 and R2 are independently selected from H, CORA, or NRBCORA, or optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, or heterocyclic moieties; or R1 and R2 are fused to form: 3 to 8 membered spirocyclic alkyl, alkenyl or heterocyclic rings; RA is H or optionally substituted alkyl, aryl, alkoxy, or aminoalkyl groups; RB is H, C1 to C3 alkyl, or substituted C1 to C3 alkyl; R3 is H, OH, NH2, CORC or optionally substituted alkyl, alkenyl, or alkynyl; RC is H or optionally substituted alkyl, aryl, alkoxy, or aminoalkyl; R4 is H, halogen, CN, NO2, or optionally substituted alkyl alkynyl, alkoxy, amino or aminoalkyl; R5 is an optionally substituted benzene or five or six membered ring with 1, 2, or 3 heteroatoms selected from O, S, SO, SO2 or NR6; R6 is H or C1 to C3 alkyl; G1 is O, NR7, or CR7R8; G2 is CO, CS, or CR7R8; provided that when G1 is O
    Type: Grant
    Filed: December 17, 2001
    Date of Patent: February 17, 2004
    Assignees: Wyeth, Ligand Pharmaceuticals Inc.
    Inventors: Puwen Zhang, Andrew Fensome, Eugene A. Terefenko, Jay E. Wrobel, James P. Edwards, Todd K. Jones, Christopher M. Tegley, Lin Zhi
  • Patent number: 6692702
    Abstract: A method for utilizing a filtration device for removing interferants from a sample containing cells in an automated apparatus is disclosed. The filtration device includes a microporous hollow fiber membrane having a plurality of pores sized to retain cells while allowing smaller diameter interferants to pass through the membrane. The apparatus also includes a means for of moving the sample from a sample container to and from the filtration device. The disclosed method utilizes a vacuum source to aspirate the sample into a lumen of the hollow fiber membrane so that the sample is retained in the lumen space until expelled into an analysis container or transported to an analyzer.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: February 17, 2004
    Assignee: Coulter International Corp.
    Inventors: Alexander Burshteyn, John W. Joubran, Nazle Kuylen, Frank J. Lucas
  • Patent number: 6692968
    Abstract: A method for utilizing a filtration device for removing interferants from a test sample containing a mixture of a composition of interest and interferants in an automated apparatus is disclosed. The filtration device includes a microporous hollow fiber membrane having a plurality of pores sized to retain the composition of interest while allowing smaller diameter interferants to pass through the membrane.
    Type: Grant
    Filed: September 20, 2001
    Date of Patent: February 17, 2004
    Assignee: Coulter International Corp.
    Inventors: Alexander Burshteyn, John W. Joubran, Nazle Kuylen, Frank J. Lucas, Carlos L. Aparicio, Michael L. Bell, Ravinder Gupta, Maria Elena Insausti, Jack D. McNeal, Paul W. Price, Sandra Socarras
  • Patent number: 6685589
    Abstract: A silent chain is provided with strength and elongation of respective link rows made uniform, elongation of every link made equal regardless of elastic and/or plastic deformation, and inexpensive production cost. The silent chain includes a first link row, a second link row, a connection pin and a pin stopper. Each of the first and second link rows consists of a guide plate and the same number of link plates whose shapes and sizes are the same. The first and second link rows are staggered in the longitudinal direction of the chain, and connected in alternating, interleaved relationship by connection pins. The guide plates and the link plates of the first and second link row are relatively rotatable to the connection pins. The first and second link rows are alternately arranged in mirror image symmetry.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: February 3, 2004
    Assignee: Tsubakimoto Chain Co.
    Inventors: Hiroshi Horie, Toyonaga Saito, Toshifumi Sato
  • Patent number: 6680330
    Abstract: This invention provides non-immunosuppressive rapamycin dialdehydes, which are useful as neurotrophic agents, in the treatment of solid tumors, and vascular disease.
    Type: Grant
    Filed: August 22, 2002
    Date of Patent: January 20, 2004
    Assignee: Wyeth
    Inventors: Tianmin Zhu, Mahdi B. Fawzi
  • Patent number: D487593
    Type: Grant
    Filed: November 22, 2002
    Date of Patent: March 16, 2004
    Assignee: PZ HTL Spolka Akcyjna
    Inventor: Wojciech Sarna