Abstract: Pathological binaural phase time delay (PBTD) asynchrony is measured at a variety of frequencies and speech stimuli to develop a BPTD profile for a subject. A corrective device (600, 1000) is designed to apply clinical PBTD to compensate for the subject's pathological BPTD. An electronic device (500) is used to measure the subject's ability to comprehend words at a variety of relative time delays between ears to estimate the ideal overall relative time delay. The optimal relative phase shift at a variety of frequencies is also measured. An electronic device (600) may be used to correct the pathological BPTD by delaying sound in different frequency bands differently to the target ear, according to the BPTD profile, or a passive filtered earplug (1000) may be used to correct smaller amounts of BPTD.

Abstract: In one embodiment, an apparatus for a remote monitoring device is disclosed. The apparatus includes a casing to fit at least one of a storage location for storage media and handling mechanisms for the storage media, the storage location and the handling mechanisms being part of a media storage library, one or more monitoring devices within the casing to obtain from the media storage library at least one of environmental measurements and images of components in the media storage library, and a communication transmitter within the casing and communicatively coupled to the one or more monitoring devices to transmit at least one of data signals representing the at least one of environmental measurements and images of the components in the media storage library. Other embodiments are also disclosed.

Abstract: In a method and apparatus for testing vehicle emissions and engine control components using a self-service on-board diagnostics (OBD) kiosk, a stand-alone kiosk includes a computing device capable of gathering VIN information and OBD information from a vehicle using a VIN reader and OBD reader. The kiosk generates a readable display or printed report for the kiosk operator indicating any detected diagnostic trouble codes found during the OBD test. By networking a plurality of kiosks together in a secure network and accessible to the Internet, an OBD kiosk network maintains a centrally located vehicle interface database for storing and retrieving pertinent vehicle-related information during OBD testing.

Abstract: A system for spatially selective, fixed-optics fluorescence detection in a multichannel polymeric microfluidic device, and a method for performing spatially selective, fixed-optics fluorescence detection.

Abstract: The present invention provides methods, nucleic acid constructs, and kits for selectively deleting a region of a nucleic acid sequence. Specifically, it utilizes retargeting retroelements to place site-specific recombination sites at targeted locations in the nucleic acid sequence. The region between the recombination sites is then deleted using a site-specific recombination system.

Abstract: The invention generally provides a biomarker for sleepiness, a method for detecting sleepiness, and a method of identifying nucleic acids associated with sleepiness.

Abstract: The present invention provides a combination of antioxidants that effectively stabilize different types of fats utilized in a ruminant diet. When included in a ruminant feed ration or water source, the antioxidant combination typically increases nutrient digestion, such as fiber and protein, improves rumen fermentation, improves microbial growth, improves microbial efficiency, increases milk production and/or milk fat, improves antioxidant status of the ruminant, and attenuates the negative effects of some fats in the ruminant animal.

Abstract: A method and system is provided to access one or more historical incident databases, for example, CDC, CPSC, DTI, AAPCC and the like, for standardizing the potentially differing categories and coding among the databases. The standardizing includes recoding of the categories by providing a unified set of categories reflective of similar categories found among the one or more databases, if any. Submission of search queries allows users to obtain unified data across the databases so that incident history statistics for one or more products tracked by commonly available databases may be easily acquired. The resulting reports and statistics may be used by various entities to understand historical incidents from multiple perspectives including, for example, injury and fatality statistics as a function of age group, type of injury, time periods, diagnosis, injury outcome, severity, and the like. Data may be presented in standardized formats or in any of the native database formats.

Abstract: A magnetic resonance imaging scanner acquires diffusion-weighted imaging data. A reconstruction engine reconstructs the acquired diffusion-weighted imaging data into diffusion-weighted image representations. A diffusion tensor engine constructs a diffusion tensor map of an area of an interest of a subject. An eigenvalue/eigenvector ordering engine obtains and orders eigenvectors and eigenvalues at each voxel. A covariance matrix determining engine constructs a covariance matrix of a major eigenvector of each voxel. A first normalized measure determining engine computes a first normalized measure. A second normalized measure determining engine computes a second normalized measure. A rendering engine generates a human-viewable display of an image representation.

Abstract: The present invention relates to a first group of novel oligonucleotides, here identified as genomic address messenger or GAM oligonucleotides, and a second group of novel operon-like polynucleotides, here identified as genomic record or GR polynucleotides. GAM oligonucleotides selectively inhibit translation of known target genes, many of which are known to be involved in various diseases. Nucleic acid molecules are provided respectively encoding 1708 GAM oligonucleotides, and 246 GR polynucleotides as are vectors and probes both comprising the nucleic acid molecules, and methods and systems for detecting GAM oligonucleotides and GR polynucleotide and specific functions and utilities thereof, for detecting expression of GAM oligonucleotides and GR polynucleotides and for selectively enhancing and selectively inhibiting translation of the respective target genes thereof.

Abstract: The present invention relates to novel 1,3-dihydroindol-2-one (oxindole) derivatives of the formula (I) in which A, R3, R4, R5 R6 and R7 are defined according to claim 1, and to medicaments containing them for the treatment of diseases. In particular, the novel oxindole derivatives can be used for the control and/or prophylaxis of various vasopressin-dependent or oxytocin-dependent diseases.

Abstract: A system and method for navigating Internet content with a limited or non-existent return channel, limited bandwidth and/or a set-top box with limited processing power.

Abstract: A system for transmitting auxiliary data within a modulated video signal from a broadcast source to a hand-held device with a slot, the system comprising the broadcast source comprises means for transmitting auxiliary data to the slotted hand-held device via the modulated video signal; an interface device electronically coupled to the hand-held device via the slot and comprises a card microcontroller, a receiver electronically coupled to the card microcontroller for receiving the modulated video signal from the broadcast source, and circuitry electronically coupled to the card microcontroller and the receiver for demodulating the modulated video signal and reproducing the auxiliary data, and transferring the auxiliary data to the hand-held device via an interface protocol, and the hand-held device with the slot comprises a microcontroller for processing the signal auxiliary data received via the interface protocol from the interface device.

Abstract: The present invention provides lysis reagents, containers, methods and kits relating to the extraction or the extraction and isolation of a cellular component from a host cell. More specifically, the invention provides combinations of zwitterionic compounds that may be employed to aide in the extraction or the extraction and isolation of a cellular component from a host cell.

Abstract: A ball valve comprising: a valve body with a seat for housing a ball provided with a coaxial through-opening and able to be rotationally operated from a closed valve position into an open valve position and vice versa; two opposite end flanges which are constrained to the valve body on opposite sides of the ball and provided with a respective, coaxial, internal hole and are suitable for connection to respective pipe sections; sealing means arranged between the valve body and the ball and comprising an annular member which is coaxial with the longitudinal axis (X-X) and carries an axial seal housed inside an associated axial seat inside which it is partially inserted in order to interfere with the outer surface of the ball, comprising a coaxial ring axially constrained to the annular seal-carrying member and interfering in the transverse direction (Y-Y) with a front surface portion of the seal in order to retain the latter in the axial direction.

Abstract: Automatically executing commands to process code (e.g., compile commands, interpret commands, etc.) and recording code characteristic metric values (e.g., file size, execution time, etc.) allows automatic code tuning. The automatic turning system may execute predefined commands on codes, automatically intelligently build commands, both execute predefined commands and intelligently build upon those predefined commands, etc. With the automatic intelligent building of commands to build more effective commands, an automatic tuning system can efficiently and judiciously search through available code development tool options to find the more effective combinations of options to generate executable codes.

Abstract: Optical cells include a spacer formed of a hydrocarbon-resistant polymer, so that fluids such as hydrocarbons and alcohols can be introduced to a sample space, or include a fluid inlet and a heated inlet tube, so that a humid gas can be introduced to the sample space without condensation occurring. Optical cells can be used with, for example, solid, gel, and liquid samples. Measurements can be performed with various selected sample gaps of an optical cell.

Abstract: The present invention provides chemokine receptor antibodies that selectively bind to an activated form of the receptor but not to a non activated form of the receptor. In particular, the current invention provides phosphospecific chemokine receptor antibodies. The antibodies can be used in several diagnostic, screening and purification methods.

Abstract: The present invention relates to methods of diagnosing, monitoring, and assessing treatment effects for neurological and neurodegenerative diseases and disorders, such as Alzheimer's Disease, early in the course of clinical disease or prior to the onset of brain damage and clinical symptoms. Methods of measuring the in vivo metabolism of biomolecules produced in the CNS in a subject are provided.

Abstract: A countercurrent chromatography apparatus includes a plurality of plates, at least one plate (16) having first and second interleaved spiral flow channels (52, 54, 56, 58) therein. Each spiral flow channels (52, 54, 56, 58) has a first end (I1, I2, I3, I4) near the central axis and a second ends (O1, O2, O3, O4) near the periphery. The outlet of the first channel (O1) is connected to the inlet of the second channel (I2) by a connecting channel (72). Septa may be provided between the plates to connect the spiral channels of one plate to the spiral channels of the next plate.