Abstract: The present invention is directed towards a method, a composition and an article of manufacture for protecting the skin from jellyfish stings. The method comprises topically contacting the skin with a composition containing polymeric quaternary ammonium salt in amounts sufficient to protect against the rupture of jellyfish nematocysts. The composition can be in the form of an emulsion, liquid dispersion, solution, skin cream, face cream, lotion or ointment.
Type:
Grant
Filed:
July 21, 1997
Date of Patent:
September 28, 1999
Assignees:
Schering-Plough HealthCare Products, Inc., University of Maryland, Baltimore
Inventors:
Richard V. Smerbeck, James R. Johnson, Joseph W. Burnett, Jennifer E. Purcell
Abstract: The invention encompasses oil-in-water type emulsion formulations having decreased skin rub-in times, comprising a nonaqueous phase, an aqueous phase and an oil-in-water emulsifier, which emulsion formulation also contains a water-in-oil emulsifier.
Type:
Grant
Filed:
December 18, 1996
Date of Patent:
June 29, 1999
Assignee:
Schering-Plough HealthCare Products, Inc.
Abstract: Sunscreen emulsion formulations of the oil-in-water type containing an aqueous phase, an emulsifier, and an oil phase comprising at least one ultraviolet-absorbing organic compound and hydrophobically treated silica particles, wherein the concentration of said organic compounds is at least about 30 times the concentration of the silica.
Type:
Grant
Filed:
November 26, 1997
Date of Patent:
June 22, 1999
Assignee:
Schering-Plough HealthCare Products, Inc.
Abstract: The administration of aerosolize particles of mometasone furoate in the form of dry powders, solutions, or aqueous suspension for treating corticosteroid-responsive diseases of the surfaces of upper and/or lower airway passages and/or lungs, e.g., allergic rhinitis and asthma is disclosed.
Type:
Grant
Filed:
August 14, 1997
Date of Patent:
March 30, 1999
Assignee:
Schering Corporation
Inventors:
Joel A. Sequeira, Francis M. Cuss, Keith B. Nolop, Imtiaz A. Chaudry, Nagamani Nagabhushan, James E. Patrick, Mitchell Cayen
Abstract: Relief from the symptoms of rhinitis is obtained by treatment with: (a) an antihistaminic effective amount of a histamine H.sub.1 receptor antagonist; together with (b) a sufficient amount of a histamine H.sub.3 receptor antagonist to provide a nasal decongestant effect. The components may be administered together in a single dosage form, or separately in the same or different dosage forms to maintain therapeutic systemic levels of both components.
Abstract: The administration of aerosolize particles of mometasone furoate in the form of dry powders, solutions, or aqueous suspension for treating corticosteroid-responsive diseases of the surfaces of upper and/or lower airway passages and/or lungs, e.g., allergic rhinitis and asthma is disclosed.
Type:
Grant
Filed:
March 20, 1997
Date of Patent:
November 17, 1998
Assignee:
Schering Corporation
Inventors:
Joel A. Sequeira, Francis M. Cuss, Keith B. Nolop, Imtiaz A. Chaudry, Nagamani Nagabhushan, James E. Patrick, Mitchell Cayen
Abstract: A powder inhaler comprising:a powder housing for holding a supply of powdered material to be dispensed and a metering plate for holding a metered amount of said powdered material, the metering plate being alternately positionable below said supply of powdered material or within an inhalation conduit, by means of a bi-directional, angle-limited relative rotation about a common central axis;a counter for providing a visual count of the number of doses of said powdered material that have been dispensed or remain to be dispensed in response to the relative rotation, the counter including: a continuous counter ring and a coaxially mounted intermittent counter ring, both rings being mounted on a base in surrounding relation to a retaining post, being rotatable about the common central axis and having counting indicia thereon for displaying said visual count; anda display means through which at least one of the counting indicia is displayed to indicate a count corresponding to a number of doses of powdered material
Type:
Grant
Filed:
June 1, 1995
Date of Patent:
November 3, 1998
Assignee:
Schering Corporation
Inventors:
Thomas J. Ambrosio, Charles R. Ashley, Alan J. Bilanin, Charles M. Huck, Andrew E. Kaufman, David J. Kenyon, Srinivas Manthena, Henry R. Sochon, Ken Wilkinson, Tsong-Toh Yang
Abstract: Apparatus for simulating skin tanning comprises a receptacle containing a fluid comprising dihydroxyacetone, a receptacle containing a fluid comprising an amino acid, and dispensing means for simultaneously or sequentially providing desired amounts of dihydroxyacetone and amino acid.
Type:
Grant
Filed:
November 13, 1995
Date of Patent:
October 27, 1998
Assignee:
Schering-Plough HealthCare Products, Inc.
Inventors:
James E. McShane, Carl Kaplan, Thomas A. Meyer
Abstract: Apparatus for simulating skin tanning comprises a receptacle containing a fluid comprising dihydroxyacetone, a receptacle containing a fluid comprising a primary amine, and dispensing means for simultaneously or sequentially providing desired amount of dihydroxyacetone and amine.
Type:
Grant
Filed:
September 13, 1996
Date of Patent:
May 26, 1998
Assignee:
Schering-Plough HealthCare Products, Inc.
Abstract: A simulated skin tan is obtained by simultaneously or sequentially applying a fluid formulation comprising dihydroxyacetone and a fluid formulation comprising a secondary polyamine, wherein the polyamine formulation also contains a color modifier which is: an amino acid; a substituted ethylenediamine; and mixtures of any two or more of the foregoing.
Type:
Grant
Filed:
March 12, 1997
Date of Patent:
May 12, 1998
Assignee:
Schering-Plough HealthCare Products, Inc.
Inventors:
Thomas A. Meyer, Michael E. Ando, Jimmy B. Powell
Abstract: A colored, sunscreen emulsion is disclosed which employs a water-soluble dye or a blend of water-soluble dyes whose color substantially disappears when the sunscreen emulsion dries after it is spread on the skin and/or is rubbed out. The coloration in the sunscreen enables the user to more effectively protect against sunburn by allowing more complete and uniform coverage of the sunscreen on the skin.
Type:
Grant
Filed:
November 25, 1996
Date of Patent:
May 5, 1998
Assignee:
Schering-Plough HealthCare Products, Inc.
Abstract: A powder dispenser includes a powder housing for holding a supply of powdered material to be dispensed, the powder housing including an inhalation conduit provided displaced relation to the powdered material supply; a metering plate including a metered dose hole for holding a metered amount of the powdered material, and positioned below the powdered material supply, the metering plate and the powder housing being relatively rotatable with respect to each other about a common central axis; a counter providing a visual count of the number of doses of the powdered material that have been dispensed or remain to be dispensed in response to the relative rotation, the counter including counter rings providing the visual count, the counter rings being rotatable about the common central axis and having indicia thereon which display the visual count, and an actuating mechanism rotatable about the central axis for incrementally rotating the counter rings in response to the relative rotation; a nozzle for breaking up agg
Type:
Grant
Filed:
June 1, 1995
Date of Patent:
April 21, 1998
Assignee:
Schering Corporation
Inventors:
Charles R. Ashley, Charles M. Huck, Henry R. Sochon, Ken Wilkinson
Abstract: A powder dispenser includes a powder housing for holding a supply of powdered material to be dispensed, the powder housing including an inhalation conduit provided displaced relation to the powdered material supply; a metering plate including a metered dose hole for holding a metered amount of the powdered material, and positioned below the powdered material supply, the metering plate and the powder housing being relatively rotatable with respect to each other about a common central axis; a counter providing a visual count of the number of doses of the powdered material that have been dispensed or remain to be dispensed in response to the relative rotation, the counter including counter rings providing the visual count, the counter rings being rotatable about the common central axis and having indicia thereon which display the visual count, and an actuating mechanism rotatable about the central axis for incrementally rotating the counter rings in response to the relative rotation; a nozzle for breaking up agg
Type:
Grant
Filed:
June 1, 1995
Date of Patent:
November 18, 1997
Assignee:
Schering Corporation
Inventors:
Thomas J. Ambrosio, Alan J. Bilanin, Andrew E. Kaufman, David J. Kenyon, Srinivas Manthena, Tsong-Toh Yang
Abstract: Apparatus for simulating skin tanning comprises a receptacle containing a fluid comprising dihydroxyacetone, a receptacle containing a fluid comprising a secondary polyamine, and dispensing means for simultaneously or sequentially providing desired amounts of dihydroxyacetone and polyamine.
Type:
Grant
Filed:
June 6, 1995
Date of Patent:
July 8, 1997
Assignee:
Schering-Plough HealthCare Products, Inc.