Abstract: A soft, tacky polysiloxane elastomer characterized as having: a tackiness of 10-450 grams as determined by a polyken probe tack tester or 0-10 cm (0-4 inches) as determined by a rolling ball tack tester and a tensile strength of 0.14-5.52 mega Pascals (20-800 pounds/square inch), a minimum elongation of 250-1100 percent and a tear strength of 0.88-35.2 kN/m (5-200 pound/square inch) The soft, tacky elastomer can be made into various cushioning devices, with or without a topcover. Representative cushioning devices include an arch support pad, a metatarsal pad, a heel cushion, sheet padding, a full-length insole, a three quarter length insole, a half insole, a toe-crest pad, a heel liner, an elbow pad, a corn pad, a callus pad, a blister pad, a bunion pad or a toe pad.

Abstract: An applicator 10 includes a barrel 12 for containing a semisolid medicinal, the barrel including a large diameter cylindrical section 16, a small diameter cylindrical section 18 and an annular sloped transition section 20 that connects the large diameter cylindrical section and the small diameter cylindrical section, the sections being coaxial with each other, the small diameter cylindrical section including an inner surface defining an internal cavity for containing the medicinal, a first end 30 with a first opening 32 and equiangularly spaced, axially aligned evacuation channels 28 in the inner surface for venting air out of the barrel when the internal cavity is filled with the medicinal, and the large diameter cylindrical section includes a second opposite end with a second opening 24; a rubber plunger 58 for pushing the medicinal through the first opening, the plunger being slidably positioned in sealing contact with the inner surface of the small diameter cylindrical section; a plunger rod 86 connected

Abstract: Aerosol formulations substantially free of chlorofluorocarbons for oral and/or nasal administration are described. The formulations comprise 1,1,1,2,3,3,3-heptafluoropropane, a medicament, optionally an excipient and optionally a surfactant. Methods of treatment utilizing the formulations are also described.

Abstract: A method for treating onychomycosis without drilling a hole in a nail plate or without daily scraping of the nail, comprising topically administering to the afflicted nail of a mammali) a medicated device comprising salicylic acid or a salt, ester or mixture thereof in a plaster preparation, wherein said plaster preparation is attached to a carrier and the salicylic acid is present in the plaster preparation in an amount ranging from about 10 to about 80 percent (%) by weight of the plaster preparation; orii) a liquid preparation comprising salicylic acid or a salt, ester or mixture thereof in a film-forming liquid vehicle, and the salicylic acid is present in the liquid preparation in an amount ranging from about 6 to about 35% by weight of the liquid preparation.

Abstract: Non-aqueous sunscreen compositions containing an amount of a volatile silicone oil sufficient to maintain the SPF of the waterproof composition at a value greater than about 20 and a conventional non-aqueous sunscreen formulation or a conventional non-aqueous waterproof sunscreen formulation.

Abstract: Apparatus for performing immunoassays which is essentially self-contained, requiring only the introduction of a sample and, at appropriate times, washing solution. The apparatus (10) includes: a fluid container (12) having a central platform area with a reaction area (30) which can contain a reactive agent; a sample receiving chamber (22) having a sample conduit (24) located above the porous medium; at least one openable reagent container (46); a conduit (28) for directing reagents onto the porous medium; an opening member (50) attached to the upper unit and positioned to contact and open reagent containers sequentially, by incremental relative rotation of the upper and base units; and a window (34) for viewing the reaction area. The apparatus can also include a sampler member (58) in the nature of a tampon for assays involving samples taken from body cavities.

Abstract: A powder dispenser 10 includes a powder housing 28 for holding a supply of powdered material to be dispensed, the powder housing including a first conduit 32 extending there through in displaced relation to the powdered material; a metering plate 16 having only a single receptacle area 24 for holding a metered amount of the powdered material above a gas-permeable powder retainer 26 mounted at the metering plate, and being positioned below the powdered material, and the metering plate and the powder housing being rotatable with respect to each other so that the receptacle area is adapted to be in selective communication with the supply of powdered material or the first conduit; a base housing 48 being mounted below the metering plate and including a second conduit 52 in alignment with the first conduit at least concurrently with alignment of the receptacle area and the first conduit; a spring 62 for biasing the base housing and the powder housing toward each other; a mouthpiece 92 for enabling inhalation of th