Abstract: The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days.

Abstract: Methods for the treatment and prevention of a bacterial infection caused by Neisseria gonorrhoeae, or Chlamydia trachomatis, or both Neisseria gonorrhoeae and Chlamydia trachomatis, such as urethritis, an ocular infection, or a pharyngeal infection, using fusidic acid, or pharmaceutically acceptable salt thereof, are described.

Abstract: A roaming service method in a mobile broadcasting system and a system thereof are provided. A terminal receives a service guide from a corresponding visited service provider (Visited SP) when the terminal moves to a roaming area. The terminal transmits a roaming request message for requesting a purchase item allowable for individual services to a home service provider (Home SP) based on the received service guide. Upon receipt of the roaming request message, the Home SP negotiates roaming availability and allowable scope for each individual service with the Visited SP where the terminal is located, based on the roaming request message. The Home SP transmits the roaming availability and allowable scope for the individual service, negotiated with the Visited SP, to the terminal.

Abstract: An apparatus and method are provided for determining a patient's carbohydrate to insulin ratio (CIR) and insulin sensitivity factor (ISF), and using these values, along with values for current blood glucose level and deviation from target blood glucose level, for determining insulin dose in view of carbohydrate intake during a particular time period. The apparatus and method employ algorithms that can be implemented in any of a personal computer, personal data assistant, hand held computing device, blood glucose monitor, infusion pump, medication delivery pen, meter, calculator, among other therapeutic, diagnostic or informational devices used for managing a patient's blood glucose levels.

Abstract: Provided is an enzyme that is further advantageous in terms of practical aspects when compared to publicly known enzymes for blood sugar sensors, and that can be used in a blood sugar level measuring reagent A flavin adenine dinucleotide-dependent glucose dehydrogenase that has amino acid sequence including a specific amino acid in an amino acid sequence shown in SEQ ID NO:2 or an amino acid sequence that has 60% homology therewith, and that has an improved temperature dependency.

Abstract: There are disclosed a water-absorbent resin composition and its production process, wherein the water-absorbent resin composition causes little gel-blocking and is excellent in the liquid permeability and liquid diffusibility and is high also in the absorption performances and further is strong also against the physical damage; and there are further disclosed a water-absorbent resin composition and its production process, wherein the water-absorbent resin composition has the following further advantages, in addition to the above, of involving little segregation of the metal compound and further having a dust prevention effect.

Abstract: Disclosed is a method for providing a broadcast service in a mobile communication system including a plurality of cells. The method includes transmitting broadcast program information related to available broadcast programs, broadcast-related information needed for receiving the available broadcast programs, and broadcast zone identification information, to an access terminal; and transmitting the broadcast service to the access terminal.

Abstract: A damping system, in particular in the form of a hydraulic cabin spring system, has at least one hydraulically triggerable actuating part (20) and has at least one hydraulic accumulator (26) connected to the actuating part (20). By a proportional throttle valve (10), proportional damping for the actuating part (20) is achieved. Variable proportional damping which can react to events in a manner specific to the user can be implemented.

Abstract: Reagents and compositions for use in reactions catalysed by luciferase enzymes, and in particular for use in luciferase-based gene reporter assays are described. The invention also provides methods and compositions for, inter alia, increasing the sensitivity and/or improving the kinetics of luciferase-catalysed reactions.

Abstract: An apparatus and method for transmitting and receiving packet data using multiple antennas in a wireless communication system is provided. In a wireless communication, system using multiple antennas, the apparatus and method can efficiently transmit and receive packet data according to channel conditions without a waste of transmission bandwidth.

Abstract: A foot pad for relieving pain while engaging in weight bearing activity is provided. A pad can include an arch portion fitting under and adjacent to the medial longitudinal arch of the foot, offsetting the soft tissue of the medial longitudinal arch thereby supporting the calcaneo-navicular ligament structure, wherein the arch portion extends from front to rear, of the longitudinal medial arch, and the arch portion extends from the medial side towards the lateral side, of the longitudinal medial arch.

Abstract: A method and apparatus for a wireless telephone having at least two speakers include a first speaker mounted on a folder housing of the wireless telephone; and a second speaker mounted on a body housing of the wireless telephone. The first and second speakers can be a telephone conversation speaker or a multimedia speaker, where the multimedia speaker outputs a message reception alert tone or a ringing tone. The method and apparatus further include a rotary section for rotating the folder housing, where the first or second speakers can be mounted on the rotary section.

Abstract: An apparatus (1) for monitoring the state of a protective device (2) of a machine (4) in particular is a safety switch for monitoring the closed state of a protective door or the like. The apparatus (1) has a switch housing (22) with a switch head (24) and an actuator (8). In the closed state of the protective device (2), the actuator interacts with the switch head (24) and, as a result, the closed state of the protective device (2) can be signaled. The apparatus (1) has a tumbler device (20) with a tumbler element (30) mounted movably in the apparatus (1) and by which the closed state of the protective device (2) can be locked releasably. The tumbler device (20) has at least one permanent magnet (34).

Abstract: The invention relates to a mixture of compounds having the sensory properties of wintergreen, to fragrance and flavoring compositions containing said mixture and to flavored and perfumed products containing said mixture, to a method of adding a wintergreen flavor, odor or note to (non-wintergreen) flavored or perfumed products. Further the present invention relates to the use of said mixture as an enhancement, or as complete or partial replacement for methyl salicylate, in particular in chewing gum, foods, dentrifices, mouthwashes and other orally consumable products. The mixture comprises or consists of dihydroanethole, o-anisaldehyde, 1,3-dimethoxybenzene, 2?-hydroxyacetophenone, and optionally 2-methoxyacetophenone.

Abstract: A filter element includes a filter material (10) having individual filter folds (12) folded in a star-like manner. At least one fluid-permeable support element (26) extends at least partially in the space between two adjacent filter folds (12) and/or on the inner peripheral side and/or external peripheral side of the filter folds (12). The support element (26) is provided with filter-active substances or is made of filter-active substances. A certain type of filter auxiliary agent can be obtained which is used to reduce influences of fluid components which reduce the service life, in the form of specific ageing products or in the form of other agents which damage the fluid.

Abstract: A problem that the present invention is to solve is to provide: a main body of a peptide molecule which is effective for inhibition of various maladies such as osteoporosis, osteoarthritis and pressure ulcer, particularly, a dipeptide which is easy to absorb into a body in an intestine; a collagen peptide which comprises the dipeptide as an essential dipeptide; and a malady inhibitor which comprises the dipeptide as an essential effective component. As a means of solving such a problem, a collagen peptide according to the present invention is characterized by comprising a dipeptide having a structure of Hyp-Gly as an essential dipeptide. A dipeptide according to the present invention is characterized by having a structure of Hyp-Gly. A malady inhibitor according to the present invention is characterized by comprising a dipeptide having a structure of Hyp-Gly as an essential effective component.

Abstract: The invention relates to antibodies that bind to a fragment of the Response Gene to Complement-32 (RGC-32), as well as methods of using these antibodies. Particular methods of using the antibodies of the present invention include, but are not limited to, methods of detecting RGC-32 in a sample, methods of assaying cell proliferation, as well as methods of detecting and/or monitoring the progression of abnormal conditions in a subject, where the disease states are associated with the presence or absence of RGC-32.

Abstract: Disclosed is an ophthalmic composition for a soft contact lens, which is characterized in that the adsorption of a terpenoid contained in the composition onto a soft contact lens is reduced. The ophthalmic composition comprises a combination of Component (A) 0.005 to 0.01 wt % of a terpenoid and Component (B) alginic acid and/or a salt thereof.