Patents Assigned to Abbott Laboratories
  • Patent number: 12235273
    Abstract: Provided herein are compositions, systems, and methods for assessing and monitory disease stage and phases, predicting likelihood of disease progression, and predicting and monitoring responses to disease therapies (e.g., in HBV infection).
    Type: Grant
    Filed: May 3, 2019
    Date of Patent: February 25, 2025
    Assignee: Abbott Laboratories
    Inventors: Gavin A. Cloherty, Mary Kuhns, Ka-Cheung Luk, Peter J. Karabatsos
  • Patent number: 12228583
    Abstract: Example automated diagnostic analyzers and methods for using the same are disclosed herein. An example apparatus described herein includes a first carousel rotatably coupled to a base and having a first axis of rotation. The example apparatus includes a second carousel rotatably coupled to the base and vertically spaced over the first carousel such that at least a portion of the second carousel is disposed over the first carousel. In the example apparatus, the second carousel has a second axis of rotation and a plurality of vessels. The example apparatus also includes a pipetting mechanism offset from the second axis of rotation. The example pipetting mechanism is to access the first carousel and the second carousel.
    Type: Grant
    Filed: November 21, 2022
    Date of Patent: February 18, 2025
    Assignees: Abbott Laboratories, Canon Medical Systems Corporation
    Inventors: Brian L. Ochranek, David C. Arnquist, Takehiko Oonuma, Hirotoshi Tahara, Naoto Sato
  • Patent number: 12210029
    Abstract: A diagnostic analyzer includes a rotating device, a first optical reader, and a second optical reader. The rotating device includes a first darkened compartment, a second darkened compartment, and an optical path along which the first darkened compartment and the second darkened compartment travel. The first optical reader is operable to read the first darkened compartment and the second optical reader is operable to read the second darkened compartment.
    Type: Grant
    Filed: August 2, 2023
    Date of Patent: January 28, 2025
    Assignee: Abbott Laboratories
    Inventor: Robert Luoma
  • Patent number: 12201980
    Abstract: Example methods, apparatus, systems for droplet actuator fabrication are disclosed. An example non-transitory computer readable medium includes instructions that, when executed, cause at least one processor to at least control movement of a laser to cause the laser to etch an electrode pattern in a first substrate, the electrode pattern including a first set of electrodes, a second set of electrodes, and a third set of electrodes; control a printer driver to cause a hydrophobic material and a dielectric material to be applied to the second set of electrodes and not the first set of electrodes via a printer; control a bonding driver to cause a gap to be defined between the first substrate and a second substrate; and control a dicing driver to cause a portion the first substrate and a portion of the second substrate to be cut into a droplet actuator.
    Type: Grant
    Filed: November 10, 2020
    Date of Patent: January 21, 2025
    Assignee: Abbott Laboratories
    Inventors: Andrew Fischer, Adrian Petyt, Sophie Laurenson
  • Patent number: 12178592
    Abstract: Disclosed herein are methods that aid in the diagnosis and evaluation of a human subject that has sustained or may have sustained an injury to the head, such as mild or moderate, severe, or moderate to severe traumatic brain injury (TBI), using cTnI. Also disclosed are methods for determining whether to perform a head computerized tomography on a subject by detecting levels of cTnI. Finally, also disclosed are methods of outcome in subjects suffering from a mild TBI.
    Type: Grant
    Filed: August 25, 2021
    Date of Patent: December 31, 2024
    Assignee: Abbott Laboratories
    Inventors: Beth McQuiston, Frederick Korley, Agim Beshiri, Jaime Marino, Saul Datwyler
  • Patent number: 12163958
    Abstract: Disclosed herein are methods that aid in the diagnosis and evaluation of a human subject that has sustained or may have sustained an injury to the head, such as mild or moderate to severe traumatic brain injury (TBI), using an early biomarker, ubiquitin carboxy-terminal hydrolase L1 (UCH-L1). Also disclosed here are methods that aid in determining whether a human subject that has sustained an injury or may have sustained to the head would benefit from and thus receive a head computerized tomography (CT) scan based on the levels of UCH-L1. These methods involve detecting levels and changes in levels of UCH-L1 in one or more samples taken from a human subject at time points within 24 hours after the subject has sustained or may have sustained an injury to the head.
    Type: Grant
    Filed: May 10, 2021
    Date of Patent: December 10, 2024
    Assignee: Abbott Laboratories
    Inventors: Beth McQuiston, Justin Rogers, Saul Datwyler, Jaime Marino
  • Publication number: 20240374379
    Abstract: A stabilized fabric composed of a mesh or a woven fabric is disclosed as are methods of their manufacture, the manufacture of medical devices made using a stabilized fibers and stabilized medical devices are all disclosed. Fabrics can be stabilized by several techniques including: using mechanical, chemical and/or energetic fasteners at warp and weft intersections in the weave; by using various weaving techniques and fibers. Meshes can be stabilized when properly dimensioned and arranged junctions and struts of the necessary properties are used. All of these stabilized fabrics can be made of synthetic polymer materials such as ultrahigh molecular weight PE or PP and expanded PTFE.
    Type: Application
    Filed: July 22, 2024
    Publication date: November 14, 2024
    Applicant: Abbott Laboratories
    Inventors: Jay Reimer, Paul E. Ashworth
  • Patent number: 12141734
    Abstract: In one aspect, a computer readable memory medium comprising program instructions for graphically developing a connectivity driver is provided. The computer readable memory medium is a non-transitory medium. The program instructions are executable by a processor to generate a purchase order for a laboratory item, transmit the purchase order to a remote computer in order to communicate the purchase order to a vendor, receive an advance shipping notice generated in response to the purchase order, receive item information stored in an RFID tag of a tagged item received at the delivery location, and check the item information against the advance shipping notice in order to verify that the tagged item is the same as the ordered laboratory item. The purchase order specifies a delivery location.
    Type: Grant
    Filed: May 23, 2023
    Date of Patent: November 12, 2024
    Assignee: Abbott Laboratories
    Inventors: John Curtis Jones, Patrick P. Fritchie, Steve Kotlinski, Jay Brian Sailer, Pathik H. Soni, Erich Iwen, Ronald R. Hohs, William B. Williams
  • Patent number: 12115266
    Abstract: Methods and apparatus to reduce biological carryover using induction heating are disclosed herein. An example method includes washing an aspiration and dispense device. The example method includes generating an alternating electromagnetic field and introducing the aspiration and dispense device into the alternating electromagnetic field. The example method includes inductively heating the aspiration and dispense device with the alternating electromagnetic field. In the example method, the washing is to occur in concert with the heating.
    Type: Grant
    Filed: September 23, 2022
    Date of Patent: October 15, 2024
    Assignee: Abbott Laboratories
    Inventors: Brad Weston, Jeffrey Mitchell
  • Patent number: 12105100
    Abstract: Disclosed herein are methods of aiding in the diagnosis and evaluation of a subject that has sustained or may have sustained an injury to the head. For example, the present disclosure provides methods for aiding in the diagnosis and evaluation of a subject to determine whether the subject has sustained a traumatic brain injury (TBI) by detecting or measuring a combination of the levels of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) and glial fibrillary acidic protein (GFAP) in samples taken at various time points within 48 hours after the subject has sustained or may have sustained an injury to the head.
    Type: Grant
    Filed: May 10, 2021
    Date of Patent: October 1, 2024
    Assignee: Abbott Laboratories
    Inventors: Beth McQuiston, Saul Datwyler, Raj Chandran, Jaime Marino
  • Patent number: 12105098
    Abstract: Disclosed herein are methods, and kits for use in said methods, that aid in the diagnosis and evaluation of a subject that has sustained an orthopedic injury and sustained or may have sustained an injury to the head, such as mild traumatic brain injury (TBI), using ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), glial fibrillary acidic protein (GFAP), or a combination thereof. Also disclosed herein are methods, and kits for use in said methods, that aid in determining whether a subject that has sustained an orthopedic injury and sustained or may have sustained an injury to the head would benefit from and thus receive an imaging procedure, such as MRI or head computerized tomography (CT) scan based on the levels of GFAP and/or UCH-L1. These methods involve detecting levels and changes in levels of GFAP and/or UCH-L1 in biological samples taken from a subject at time points within 48 hours after the subject has sustained or may have sustained an injury to the head.
    Type: Grant
    Filed: May 10, 2021
    Date of Patent: October 1, 2024
    Assignee: Abbott Laboratories
    Inventors: Beth McQuiston, Saul A. Datwyler, Raj Chandran
  • Patent number: 12096785
    Abstract: Aqueous lipid emulsions for providing enteral nutrition are provided. The aqueous lipid emulsions include at least 33% of lipids, lipid soluble nutrients, or a combination thereof, based upon the total weight of the emulsion, and are essentially free of carbohydrate and protein. The aqueous lipid emulsions are shelf-stable for at least 7 months. The aqueous lipid emulsions are a source of supplemental enteral nutrition for any patient in need thereof, including preterm infants.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: September 24, 2024
    Assignee: Abbott Laboratories
    Inventors: Stephen J. Demichele, Mustafa Vurma, Megan Terp
  • Patent number: 12076234
    Abstract: A stabilized fabric composed of a mesh or a woven fabric is disclosed as are methods of their manufacture, the manufacture of medical devices made using a stabilized fibers and stabilized medical devices are all disclosed. Fabrics can be stabilized by several techniques including: using mechanical, chemical and/or energetic fasteners at warp and weft intersections in the weave; by using various weaving techniques and fibers. Meshes can be stabilized when properly dimensioned and arranged junctions and struts of the necessary properties are used. All of these stabilized fabrics can be made of synthetic polymer materials such as ultrahigh molecular weight PE or PP and expanded PTFE.
    Type: Grant
    Filed: October 3, 2022
    Date of Patent: September 3, 2024
    Assignee: Abbott Laboratories
    Inventors: Jay Reimer, Paul E. Ashworth
  • Patent number: 12070214
    Abstract: A device for closing a tissue opening includes a proximal housing portion having a first portion, a second portion, a third portion, and a fourth portion. The first portion and the fourth portion extending transversely to a longitudinal axis of the proximal housing portion on opposite sides of the proximal housing portion. A distal portion extends from the proximal housing portion. At least the second portion and the third portion are configured to move toward the first portion.
    Type: Grant
    Filed: May 30, 2022
    Date of Patent: August 27, 2024
    Assignee: Abbott Laboratories
    Inventors: Erik K. Walberg, Timothy C. Reynolds, Brian A. Ellingwood, Kai Yenkai Jair, Anthony J. Pantages
  • Patent number: 12007403
    Abstract: Example apparatus and methods related to automated diagnostic analyzers having rear accessible track systems are described herein. An example apparatus disclosed herein includes an analyzer to perform a diagnostic test. The analyzer has a first side and a second side opposite the first side. The example apparatus includes a loading bay disposed on the first side of the analyzer to receive a first carrier and a pipetting mechanism coupled to the analyzer adjacent the second side. The example apparatus also includes a first carrier shuttle to transport the first carrier from a first location adjacent the loading bay to a second location adjacent the pipetting mechanism and a track disposed adjacent the second side of the analyzer to transfer a second carrier to a third location adjacent the pipetting mechanism.
    Type: Grant
    Filed: September 20, 2021
    Date of Patent: June 11, 2024
    Assignees: Abbott Laboratories, Canon Medical Systems Corporation
    Inventors: Brian L. Ochranek, David C. Arnquist, Takehiko Oonuma, Hirotoshi Tahara, Naoto Sato, Bradley P. Smith
  • Patent number: 11975014
    Abstract: Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
    Type: Grant
    Filed: April 12, 2021
    Date of Patent: May 7, 2024
    Assignee: Abbott Laboratories
    Inventors: Rachael Buck, Geralyn O. Duska-Mcewen, Joseph P. Schaller
  • Patent number: 11911769
    Abstract: The instant disclosure provides nucleic acid amplification systems and multi-reaction analysis systems useful in the efficient processing of samples, including clinical samples. Integrated systems that include nucleic acid amplification devices functionally combined with multi-reaction analysis systems are also included. Also provided are methods for monitoring multiple concurrent nucleic acid amplification reactions that include the use of devices and systems described herein.
    Type: Grant
    Filed: September 30, 2020
    Date of Patent: February 27, 2024
    Assignee: Abbott Laboratories
    Inventors: Sonal Sadaria Nana, Eric B. Shain, Michael S. Hazell, Eric D. Yeaton, Michael Giraud, Timothy J. Patno, Ali Attarwalla, Dean Khan, Matthew J. Hayes
  • Patent number: 11899031
    Abstract: Cradles for draining liquid from containers are described herein. An example apparatus includes a housing having a bottom wall, a side wall and an open top. The housing is to receive a container having liquid. The example apparatus includes a probe extending upward from the bottom wall toward the open top and is to drain the liquid from the container when the probe is inserted into the container. The example apparatus also includes a sliding lock slidably disposed within the housing that receives a cap or top of the container when the container is inserted into the housing. The sliding lock includes a key slot. The sliding lock is movable when a cap or top of the container has a matching key that engages the key slot, which enables the sliding lock to move downward to expose the probe and drain the liquid from the container.
    Type: Grant
    Filed: February 10, 2022
    Date of Patent: February 13, 2024
    Assignee: Abbott Laboratories
    Inventor: Roger W. Accurso
  • Patent number: 11785974
    Abstract: Liquid nutritional compositions have an off-white color with a Hunter L value not less than 68, and comprise (a) a protein; (b) a carbohydrate; (c) an oxidizable fish oil containing an omega-3 polyunsaturated fatty acid; (d) rosmarinic acid; and (e) ferric iron comprising ferric orthophosphate and/or ferric pyrophosphate. The liquid nutritional compositions exhibit reduced off-flavors and aromas typically encountered in compositions including fish oil.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: October 17, 2023
    Assignee: Abbott Laboratories
    Inventors: Normanella Dewille, Megan Terp, Allison Atnip, Tapas Das
  • Patent number: 11733257
    Abstract: A diagnostic analyzer includes a rotating device, a first optical reader, and a second optical reader. The rotating device includes a first darkened compartment, a second darkened compartment, and an optical path along which the first darkened compartment and the second darkened compartment travel. The first optical reader is operable to read the first darkened compartment and the second optical reader is operable to read the second darkened compartment.
    Type: Grant
    Filed: May 24, 2021
    Date of Patent: August 22, 2023
    Assignee: Abbott Laboratories
    Inventor: Robert Luoma