Patents Assigned to Abbott Laboratories
  • Publication number: 20210045868
    Abstract: A stabilized fabric composed of a mesh or a woven fabric is disclosed as are methods of their manufacture, the manufacture of medical devices made using a stabilized fibers and stabilized medical devices are all disclosed. Fabrics can be stabilized by several techniques including: using mechanical, chemical and/or energetic fasteners at warp and weft intersections in the weave; by using various weaving techniques and fibers. Meshes can be stabilized when properly dimensioned and arranged junctions and struts of the necessary properties are used. All of these stabilized fabrics can be made of synthetic polymer materials such as ultrahigh molecular weight PE or PP and expanded PTFE.
    Type: Application
    Filed: September 30, 2020
    Publication date: February 18, 2021
    Applicant: Abbott Laboratories
    Inventors: Jay Reimer, Paul E. Ashworth
  • Publication number: 20210038620
    Abstract: Disclosed are nutritional compositions including human milk oligosaccharides and nucleotides that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
    Type: Application
    Filed: October 23, 2020
    Publication date: February 11, 2021
    Applicant: ABBOTT LABORATORIES
    Inventors: Rachael Buck, Debra Thomas, Joseph Schaller
  • Patent number: 10913064
    Abstract: Example methods, apparatus, systems for droplet actuator fabrication are disclosed. An example method disclosed herein for making a droplet actuator includes ablating a first substrate with a laser to form an electrode array on the first substrate. The example method includes applying at least one of hydrophobic or a dielectric material to the electrode array. The example method also includes aligning the first substrate with a second substrate. The second substrate includes a second treated layer. In the example method, the alignment includes a gap between at least a portion of the first treated layer and at least a portion the second treated layer.
    Type: Grant
    Filed: April 15, 2015
    Date of Patent: February 9, 2021
    Assignee: Abbott Laboratories
    Inventors: Andrew Fischer, Adrian Petyt, Sophie Laurenson
  • Patent number: 10912323
    Abstract: A nutritional supplement powder and a method of making the nutritional supplement powder are provided. The nutritional supplement powder includes from 20% by weight to 55% by weight protein, from 20% by weight to 50% by weight fructooligosaccharide powder, and an anti-caking mixture that includes calcium silicate and tricalcium phosphate. A weight ratio of the fructooligosaccharide powder to the anti-caking mixture is from 6:1 to 10:1.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: February 9, 2021
    Assignee: ABBOTT LABORATORIES
    Inventors: Deborah Strozier, Ronald McKenna, Tama Bloch, Kuochu Li
  • Patent number: 10877048
    Abstract: Disclosed herein are methods that aid in the hyperacute diagnosis and evaluation of a human subject that has sustained or may have sustained an injury to the head, such as mild or moderate, severe, or moderate to severe traumatic brain injury (TBI), using an early biomarker, such as ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) glial fibrillary acidic protein (GFAP), or a combination thereof. Also disclosed here are methods that aid in the hyperacute determination of whether a human subject that has sustained an injury or may have sustained to the head would benefit from and thus receive a head computerized tomography (CT) scan based on the levels of UCH-L1.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: December 29, 2020
    Assignee: Abbott Laboratories
    Inventors: Beth McQuiston, Justin Rogers, Saul Datwyler, Jaime Marino
  • Patent number: 10877038
    Abstract: Disclosed herein are methods that aid in the hyperacute diagnosis and evaluation of a human subject that has sustained or may have sustained an injury to the head, such as mild, moderate, severe, or moderate to severe traumatic brain injury (TBI), using an early biomarker, such as ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), glial fibrillary acidic protein (GFAP), or a combination thereof. Also disclosed here are methods that aid in the hyperacute determination of whether a human subject that has sustained an injury or may have sustained to the head would benefit from and thus receive a head computerized tomography (CT) scan based on the levels of UCH-L1.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: December 29, 2020
    Assignee: Abbott Laboratories
    Inventors: Beth McQuiston, Justin Rogers, Saul Datwyler, Jaime Marino
  • Patent number: 10871426
    Abstract: The present disclosure provides methods for the automated control of aspects of slide preparation in an automated slide preparation instrument. Aspects of the methods include automated assessments of reagent amounts, quality and performance as well as automated adjustments of reagents based on such assessments, including the adjustment of reagent amounts, e.g., as present in reagent baths, the adjustment of reagent compositions and the replacement of reagents. Devices and systems useful in performing the described methods are also provided herein.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: December 22, 2020
    Assignee: Abbott Laboratories
    Inventors: Svitlana Y. Berezhna, Mahmoud Janbakhsh, Ema C. Olah, Robert Langsner
  • Patent number: 10866171
    Abstract: The present disclosure provides methods for carrying out Romanowsky-type stains, specifically Wright-Giemsa and May-Grünwald stains, quickly and efficiently. The methods greatly reduce the overall amount of time required to complete a Wright-Giemsa stain or a May-Grünwald stain of sufficient quality on a biological sample. The subject methods can be applied to both manual and automated staining procedures.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: December 15, 2020
    Assignee: Abbott Laboratories
    Inventors: Abe S. Mamaghani, Koshy T. Chacko, Rupa Rao, Rene Nieves Alicea
  • Patent number: 10866187
    Abstract: Provided are methods of assessing the cleanliness of a flow cell of a flow cytometric system. The provided methods include computing a ratio of post-flow cell and pre-flow cell light beam intensities and using such a ratio to assess the cleanliness of the flow cell. Flow cytometric systems capable of monitoring the cleanliness of a flow cell contained within the system are also provided.
    Type: Grant
    Filed: April 14, 2020
    Date of Patent: December 15, 2020
    Assignee: Abbott Laboratories
    Inventors: Svitlana Y. Berezhna, JrHung T Tsai, David Spalding, Mahesh R. Junnarkar, Chia-Fa Hsu
  • Patent number: 10867274
    Abstract: In one aspect, a computer readable memory medium comprising program instructions for graphically developing a connectivity driver is provided. The computer readable memory medium is a non-transitory medium. The program instructions are executable by a processor to generate a purchase order for a laboratory item, transmit the purchase order to a remote computer in order to communicate the purchase order to a vendor, receive an advance shipping notice generated in response to the purchase order, receive item information stored in an RFID tag of a tagged item received at the delivery location, and check the item information against the advance shipping notice in order to verify that the tagged item is the same as the ordered laboratory item. The purchase order specifies a delivery location.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: December 15, 2020
    Assignee: Abbott Laboratories
    Inventors: John Curtis Jones, Patrick P. Fritchie, Steve Kotlinski, Jay Brian Sailer, Pathik H. Soni, Erich Iwen, Ronald R. Hohs, William B. Williams
  • Patent number: 10866251
    Abstract: Disclosed herein are methods that aid in the determination of whether to perform imaging, such as magnetic resonance imaging (MRI) or computerized tomography (CT) scan, on a human subject that has sustained or may have sustained an injury to the head using an early biomarker, such as ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), glial fibrillary acidic protein (GFAP), or a combination thereof. These methods involve detecting levels and changes in levels of UCH-L1 in samples taken from a human subject at time points within 24 hours after the subject has sustained or may have sustained an injury to the head.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: December 15, 2020
    Assignee: Abbott Laboratories
    Inventors: Beth McQuiston, Justin Rogers, Jaime Marino, Raj Chandran, Tianming Zhang, Saul Datwyler
  • Patent number: 10866181
    Abstract: Aspects of the present disclosure include methods for detecting events in a flow cytometer. Also provided are methods of detecting cells in a flow cytometer. Other aspects of the present disclosure include methods for determining a level of contamination in a flow cell. Computer-readable media and systems, e.g., for practicing the methods summarized above, are also provided.
    Type: Grant
    Filed: April 13, 2020
    Date of Patent: December 15, 2020
    Assignee: Abbott Laboratories
    Inventors: Amish P. Shah, Frederic M. Hulett, III
  • Patent number: 10859484
    Abstract: Provided herein is a method for determining the volume or hemoglobin content of an individual red blood cell in a sample containing a population of red blood cells. The method may be performed on a hematology analyzer. Also provided are a hematology analyzer for performing the method and a computer-readable medium containing programming for performing the method.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: December 8, 2020
    Assignee: Abbott Laboratories
    Inventors: Giacomo Vacca, Martin Krockenberger, Diana Garrett
  • Patent number: 10849548
    Abstract: Disclosed herein are methods that aid in the diagnosis and evaluation of a human subject that has sustained or may have sustained an injury to the head, such as mild or a moderate, severe, or moderate to severe traumatic brain injury (TBI), by detecting levels of cardiac troponin I (cTnI) and one or more early biomarkers which are not cTnI, such as ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), glial fibrillary acidic protein (GFAP), or a combination thereof, in biological samples taken from a human subject at time points within about 24 hours of injury after the subject has sustained or may have sustained the injury to the head.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: December 1, 2020
    Assignee: Abbott Laboratories
    Inventors: Beth McQuiston, Frederick Korley, Agim Beshiri, Jaime Marino, Saul Datwyler
  • Patent number: 10830686
    Abstract: In some aspects, a flow cytometer system is provided that includes beam shaping optics positioned to manipulate a light beam and produce a resulting light beam that irradiates the core stream at the interrogation zone of the flow cell. The beam shaping optics include an acylindrical lens positioned to receive and focus light in a direction of a first axis orthogonal to a direction of light travel, and a cylindrical lens positioned to receive the light output from the acylindrical lens and to focus the light output from the acylindrical lens in a direction of a second axis orthogonal to the first axis and to the direction of light travel. The resulting light beam output has a flat-top shaped intensity profile along the first axis, and a Gaussian-shaped intensity profile along the second axis. Related methods of shaping a light beam at an interrogation zone of a flow cell are also provided.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: November 10, 2020
    Assignee: Abbott Laboratories
    Inventors: John F. Heanue, Stuart L. Friedman
  • Publication number: 20200338103
    Abstract: Disclosed are nutritional compositions including human milk oligosaccharides that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
    Type: Application
    Filed: July 13, 2020
    Publication date: October 29, 2020
    Applicant: Abbott Laboratories
    Inventors: Rachael Buck, Geralyn O. Duska-McEwen, Joseph P. Schaller
  • Patent number: 10816551
    Abstract: The present disclosure provides methods, kits, and compositions for detecting subject anti-HCV antibodies in a sample using NS3 capture peptides. In certain embodiments, at least two NS3 helicase (NS3h) capture peptides and at least two conjugate peptides (e.g., NS3h conjugate peptides) are employed together, which allows for a broad dynamic range of subject antibody detection in a one-step type assay. In other embodiments, methods are provided of detecting NS3-specific subject antibodies without the use of a reducing agent. In some embodiments, NS3-specific subject antibodies are detected with a ‘double shot’ of NS3 conjugate peptide (e.g., conjugate peptide added to a sample both before and after washing).
    Type: Grant
    Filed: September 5, 2018
    Date of Patent: October 27, 2020
    Assignee: Abbott Laboratories
    Inventors: Anthony S. Muerhoff, John C. Prostko, Christopher C. Marohnic
  • Patent number: 10813940
    Abstract: Disclosed are nutritional compositions including human milk oligosaccharides and nucleotides that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
    Type: Grant
    Filed: September 18, 2017
    Date of Patent: October 27, 2020
    Assignee: ABBOTT LABORATORIES
    Inventors: Rachael Buck, Debra Thomas, Joseph Schaller
  • Patent number: D905866
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: December 22, 2020
    Assignee: Abbott Laboratories
    Inventors: Robert Paul Luoma, II, Brian L. Ochranek, Cheryl L. Davidson, Bradley C. Weston
  • Patent number: D910448
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: February 16, 2021
    Assignee: ABBOTT LABORATORIES
    Inventors: Timothy J. Boyd, Jeremy McBroom, Xinzhong Zhang, Jay Yuan