Abstract: Sample analysis systems and methods using assay surfaces, assay processing units (APUs), assay processing systems (APSs), and laboratory systems are disclosed. An assay surface includes a sample processing component comprising a plurality of regions, including at least one wash region and at least one storage region configured to hold a plurality of solid supports moveable through the regions under a magnetic force, and a detection component configured to receive the solid supports. An APU includes an assay surface receiving component, a magnetic element configured to generate a moveable magnetic field, and one or more processors configured to move the magnetic field. An APS includes one or more assay surfaces and an APU. A laboratory system includes one or more APSs and a controller for parallel processing. Sample processing and detection methods are disclosed with a reduced sample volume and/or shortened processing time and/or higher sensitivity.
Abstract: Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
Type:
Grant
Filed:
December 15, 2017
Date of Patent:
May 23, 2023
Assignee:
ABBOTT LABORATORIES
Inventors:
Rachael Buck, Geralyn O. Duska-McEwen, Joseph P. Schaller
Abstract: A container (210) for holding granular or powdered material and formed by a top wall (212), a bottom wall (214), a front wall (216), a rear wall (218), a first side wall (220), and a second side wall (222). A rotatably removable lid (D) is interiorly mounted with a scoop (32) and is pivotally hinged to a collar (300) that includes a sealing gasket (330). The collar (300) mounts to the walls of the container (210). A sealing wall 240 of the lid (D) cooperates with the gasket 300 to prevent the contents from spilling. The container (210) incorporates powder control features, a container wall junction (50) preferred geometry and congruent scoop (32) enabling convenient access to the contents, a tolerance variation accommodating and strength improving, J-shaped collar (300) and interlocking indentations (290) and flex clips (310), and a pressure controlling portion (350) that prevents unwanted deformation due to pressure differentials.
Type:
Application
Filed:
January 9, 2023
Publication date:
May 18, 2023
Applicant:
ABBOTT LABORATORIES
Inventors:
James P. PERRY, Craig A. MCCARDELL, Jeremy MCBROOM, David COMPEAU, Ashley A. GOHLKE, William J. HOOK, Katherine J. JORDAN, Frank S. WALCZAK, Peter B. CLARKE, J. Kevin CLAY, Richard C. DARR, Jack E. ELDER, Marc A. PEDMO, Charles R. SCHOTTHOEFER
Abstract: Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
Type:
Application
Filed:
January 20, 2023
Publication date:
May 18, 2023
Applicant:
ABBOTT LABORATORIES
Inventors:
RACHAEL BUCK, GERALYN O. DUSKA-MCEWEN, JOSEPH P. SCHALLER
Abstract: Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
Type:
Grant
Filed:
February 8, 2018
Date of Patent:
April 25, 2023
Assignee:
ABBOTT LABORATORIES
Inventors:
Rachael Buck, Geralyn O. Duska-McEwen, Joseph P. Schaller
Abstract: Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells.
Type:
Grant
Filed:
October 3, 2017
Date of Patent:
April 25, 2023
Assignee:
ABBOTT LABORATORIES
Inventors:
Jeffrey B. Huff, Mark A. Hayden, Peter J. Karabatsos, Andrew Fischer, John M. Robinson, Shelley R. Holets-McCormack, Sophie Laurenson
Abstract: A stabilized fabric composed of a mesh or a woven fabric is disclosed as are methods of their manufacture, the manufacture of medical devices made using a stabilized fibers and stabilized medical devices are all disclosed. Fabrics can be stabilized by several techniques including: using mechanical, chemical and/or energetic fasteners at warp and weft intersections in the weave; by using various weaving techniques and fibers. Meshes can be stabilized when properly dimensioned and arranged junctions and struts of the necessary properties are used. All of these stabilized fabrics can be made of synthetic polymer materials such as ultrahigh molecular weight PE or PP and expanded PTFE.
Abstract: Disclosed are nutritional compositions including 2?-fucosyllactose (2?-FL) in combination with lutein and RRR-alpha-tocopherol. The nutritional compositions are useful for improving at least one of gut function, health, and development in an individual. In certain embodiments, the nutritional compositions can improve growth or maturation of the gut, as well as promote a healthy balance of beneficial bacteria in the gastrointestinal tract thereby treating and/or preventing formula intolerance or other gastrointestinal diseases and/or disorders resulting from suboptimal gastrointestinal flora population/balance.
Abstract: Powdered nutritional products containing branched-chain amino acids and a sugar alcohol are provided. The branched-chain amino acids in the powdered nutritional product exhibit improved solubility and thus improved dissolution upon reconstitution of the powdered nutritional product.
Type:
Grant
Filed:
September 8, 2016
Date of Patent:
February 28, 2023
Assignee:
ABBOTT LABORATORIES
Inventors:
Christopher Cordle, Roger Tyre, Paul Johns, Sean Garvey, Eric Torgerson
Abstract: Digital pass verification systems and methods are disclosed herein. One or more servers are to distribute instructions on a network. The instructions, when executed, cause a first device carried by a person to at least: access a result of a diagnostic test performed on the person, the result provided by a second device; generate a machine-readable code in response to the result being negative; and display the machine-readable code on a display of the first device to enable the person to gain access to a location.
Type:
Grant
Filed:
September 15, 2021
Date of Patent:
February 7, 2023
Assignee:
Abbott Laboratories
Inventors:
Nitesh Luthra, Lev F. Frayman, Terry Finch, John Schullian, Douglas Wager, Nicholas Alexander Robertson Wood
Abstract: A stabilized fabric composed of a mesh or a woven fabric is disclosed as are methods of their manufacture, the manufacture of medical devices made using a stabilized fibers and stabilized medical devices are all disclosed. Fabrics can be stabilized by several techniques including: using mechanical, chemical and/or energetic fasteners at warp and weft intersections in the weave; by using various weaving techniques and fibers. Meshes can be stabilized when properly dimensioned and arranged junctions and struts of the necessary properties are used. All of these stabilized fabrics can be made of synthetic polymer materials such as ultrahigh molecular weight PE or PP and expanded PTFE.
Abstract: Whey protein based liquid nutritional compositions are provided. The liquid nutritional compositions include at least 7% by weight protein and all of the protein is provided by a whey protein hydrolysate and an intact whey protein. The liquid nutritional compositions have a neutral pH, a low viscosity, and are shelf stable.
Abstract: Example automated diagnostic analyzers and methods for using the same are disclosed herein. An example apparatus described herein includes a first carousel rotatably coupled to a base and having a first axis of rotation. The example apparatus includes a second carousel rotatably coupled to the base and vertically spaced over the first carousel such that at least a portion of the second carousel is disposed over the first carousel. In the example apparatus, the second carousel has a second axis of rotation and a plurality of vessels. The example apparatus also includes a pipetting mechanism offset from the second axis of rotation. The example pipetting mechanism is to access the first carousel and the second carousel.
Type:
Grant
Filed:
August 18, 2020
Date of Patent:
December 27, 2022
Assignee:
Abbott Laboratories
Inventors:
Brian L. Ochranek, David C. Arnquist, Takehiko Oonuma, Hirotoshi Tahara, Naoto Sato
Abstract: Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
Type:
Grant
Filed:
November 20, 2017
Date of Patent:
December 13, 2022
Assignee:
ABBOTT LABORATORIES
Inventors:
Rachael Buck, Geralyn O. Duska-McEwen, Joseph P. Schaller
Abstract: Digital pass verification systems and methods are disclosed herein. An apparatus disclosed herein includes memory including instructions that, when executed, cause processor circuitry to: access a result of a diagnostic test associated with a test kit identification; associate the result of the diagnostic test with a user identification; and transmit the result of the diagnostic test and the test kit identification to a first device to cause the first device to generate a machine-readable pass on a display of the first device.
Type:
Grant
Filed:
March 22, 2021
Date of Patent:
November 29, 2022
Assignee:
Abbott Laboratories
Inventors:
Nitesh Luthra, Lev F. Frayman, Terry Finch, John Schullian, Douglas Wager, Nicholas Alexander Robertson Wood
Abstract: Digital pass verification systems and methods are disclosed herein. One or more servers are to distribute instructions on a network. The instructions, when executed, cause a first device carried by a person to at least: access a result of a diagnostic test performed on the person, the result provided by a second device; generate a machine-readable code in response to the result being negative; and display the machine-readable code on a display of the first device to enable the person to gain access to a location.
Type:
Grant
Filed:
April 26, 2021
Date of Patent:
November 29, 2022
Assignee:
Abbott Laboratories
Inventors:
Nitesh Luthra, Lev F. Frayman, Terry Finch, John Schullian, Douglas Wager, Nicholas Alexander Robertson Wood