Abstract: Example automated diagnostic analyzers and methods for using the same are disclosed herein. An example apparatus described herein includes a first carousel rotatably coupled to a base and having a first axis of rotation. The example apparatus includes a second carousel rotatably coupled to the base and vertically spaced over the first carousel such that at least a portion of the second carousel is disposed over the first carousel. In the example apparatus, the second carousel has a second axis of rotation and a plurality of vessels. The example apparatus also includes a pipetting mechanism offset from the second axis of rotation. The example pipetting mechanism is to access the first carousel and the second carousel.
Type:
Grant
Filed:
August 18, 2020
Date of Patent:
December 27, 2022
Assignee:
Abbott Laboratories
Inventors:
Brian L. Ochranek, David C. Arnquist, Takehiko Oonuma, Hirotoshi Tahara, Naoto Sato
Abstract: Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
Type:
Grant
Filed:
November 20, 2017
Date of Patent:
December 13, 2022
Assignee:
ABBOTT LABORATORIES
Inventors:
Rachael Buck, Geralyn O. Duska-McEwen, Joseph P. Schaller
Abstract: Digital pass verification systems and methods are disclosed herein. An apparatus disclosed herein includes memory including instructions that, when executed, cause processor circuitry to: access a result of a diagnostic test associated with a test kit identification; associate the result of the diagnostic test with a user identification; and transmit the result of the diagnostic test and the test kit identification to a first device to cause the first device to generate a machine-readable pass on a display of the first device.
Type:
Grant
Filed:
March 22, 2021
Date of Patent:
November 29, 2022
Assignee:
Abbott Laboratories
Inventors:
Nitesh Luthra, Lev F. Frayman, Terry Finch, John Schullian, Douglas Wager, Nicholas Alexander Robertson Wood
Abstract: Digital pass verification systems and methods are disclosed herein. One or more servers are to distribute instructions on a network. The instructions, when executed, cause a first device carried by a person to at least: access a result of a diagnostic test performed on the person, the result provided by a second device; generate a machine-readable code in response to the result being negative; and display the machine-readable code on a display of the first device to enable the person to gain access to a location.
Type:
Grant
Filed:
April 26, 2021
Date of Patent:
November 29, 2022
Assignee:
Abbott Laboratories
Inventors:
Nitesh Luthra, Lev F. Frayman, Terry Finch, John Schullian, Douglas Wager, Nicholas Alexander Robertson Wood
Abstract: Disclosed are methods for detecting a target nucleic acid in a sample. The methods include contacting the sample, in the presence of a polymerase and an endonuclease, with a first oligonucleotide comprising, in the 5? to 3? direction, a first signal DNA generation sequence, an endonuclease recognition site, and a sequence complementary to the 3? end of a target nucleic acid; a second oligonucleotide comprising, in the 5? to 3? direction, a second signal DNA generation sequence, an endonuclease recognition site, and a sequence that is homologous to the first signal DNA generation sequence of the first oligonucleotide; a third oligonucleotide comprising, in the 5? to 3? direction, a third signal DNA generation sequence, an endonuclease recognition site, and a sequence that is homologous to the second signal DNA generation sequence of the second oligonucleotide.
Abstract: Disclosed embodiments provide nutritional compositions and methods of enhancing maturation of an infant's brain. The methods include the step of administering to the infant a nutritional composition comprising a protein with a degree of hydrolysis of 10% to 75% in combination with at least one of a monoglyceride, a free fatty acid, a salt of a free fatty acid, a phospholipid, and cholesterol.
Type:
Application
Filed:
June 29, 2022
Publication date:
November 3, 2022
Applicant:
ABBOTT LABORATORIES
Inventors:
TAPAS DAS, MUSTAFA VURMA, CHRON-SI LAI, PAUL JOHNS
Abstract: Methods of preparing a nutritional product which contain a lipophilic nutrient are disclosed. The nutritional product is made using a fortifying powder containing the lipophilic nutrient, a monoglyceride and diglyceride (“MDG”) oil, a phospholipid, and a carrier. The fortifying powder enhances the digestive absorption of the lipophilic nutrient when the nutritional product is consumed. The fortifying powder simplifies the process of manufacturing the nutritional product, as the fortifying powder can be added at a suitable stage of the process with other powdered ingredients. The fortifying powder may be manufactured in bulk and stored for later use, thereby improving manufacturing efficiencies. The fortifying powder and methods of preparing the fortifying powder are also presented.
Abstract: Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
Type:
Grant
Filed:
November 16, 2020
Date of Patent:
October 11, 2022
Assignee:
ABBOTT LABORATORIES
Inventors:
Rachael Buck, Geralyn O. Duska-McEwen, Joseph P. Schaller
Abstract: Methods and apparatus to reduce biological carryover using induction heating are disclosed herein. An example method includes washing an aspiration and dispense device. The example method includes generating an alternating electromagnetic field and introducing the aspiration and dispense device into the alternating electromagnetic field. The example method includes inductively heating the aspiration and dispense device with the alternating electromagnetic field. In the example method, the washing is to occur in concert with the heating.
Abstract: Disclosed are nutritional compositions including galactooligosaccharides that can be administered to individuals including preterm infants, infants, toddlers, children, and adults for preventing injury and/or improving the healing of the gastrointestinal tract. Additional suitable methods of using the nutritional compositions including the galactooligosaccharides are also disclosed.
Abstract: Diagnostic analyzers with pretreatment carousels and related methods are disclosed. An example apparatus includes a first carousel that includes a first annular array of slots to receive a first vessel. The example first carousel also includes a first track of rotation about the first carousel having a first diameter and a second track of rotation about the first carousel having a second diameter smaller than the first diameter. The example apparatus includes a first diverter to move the first vessel from the first track to the second track. In addition, the example apparatus includes a second carousel coaxial with the first carousel. The example second carousel includes a second annular array of slots to receive a second vessel.
Abstract: The present disclosure provides detection methods employing HCV core lipid binding domain and DNA binding domain monoclonal antibodies. In certain embodiments, the lipid binding domain monoclonal antibody recognizes an epitope in amino acids 141 to 161 of HCV core protein.
Type:
Grant
Filed:
April 15, 2021
Date of Patent:
August 30, 2022
Assignee:
ABBOTT LABORATORIES
Inventors:
Robert Ziemann, April Ahlberg, David Hawksworth, Bryan Tieman, A. Scott Muerhoff, Christopher Marohnic, Kathy Otis
Abstract: Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.
Type:
Grant
Filed:
April 17, 2019
Date of Patent:
August 23, 2022
Assignee:
ABBOTT LABORATORIES
Inventors:
Bailin Tu, Robert N. Ziemann, Bryan C. Tieman, Philip M. Hemken, Carol S. Ramsay, Carolyn J. Strobel, David J. Hawksworth, Larry G. Birkenmeyer, Cheng Zhao, Susan E. Brophy, Barry L. Dowell, Anthony S. Muerhoff
Abstract: Disclosed are methods of reducing the incidence of oxidative stress in infants, toddlers, and children using nutritional compositions including human milk oligosaccharides. The nutritional compositions including the human milk oligosaccharides are effective at reducing inflammation and the incidence of inflammatory diseases.
Type:
Application
Filed:
April 25, 2022
Publication date:
August 11, 2022
Applicant:
ABBOTT LABORATORIES
Inventors:
Steven R. DAVIS, Rachael BUCK, Geralyn O. DUSKA-MCEWEN
Abstract: Methods of preparing a nutritional product which contain a lipophilic nutrient are disclosed. The nutritional product is made using a fortifying powder containing the lipophilic nutrient, a monoglyceride and diglyceride (“MDG”) oil, a phospholipid, and a carrier. The fortifying powder enhances the digestive absorption of the lipophilic nutrient when the nutritional product is consumed. The fortifying powder simplifies the process of manufacturing the nutritional product, as the fortifying powder can be added at a suitable stage of the process with other powdered ingredients. The fortifying powder may be manufactured in bulk and stored for later use, thereby improving manufacturing efficiencies. The fortifying powder and methods of preparing the fortifying powder are also presented.