Patents Assigned to Abbott Laboratories
  • Publication number: 20200323630
    Abstract: At least a portion of fabrics for use in medical devices is formed from polymeric materials. The fabrics may be uncoated, partially coated or fully coated with one or more layers of a polymer. The fabrics may be used for the leaflets and/or cuffs of prosthetic heart valves and as a component of other medical devices.
    Type: Application
    Filed: June 11, 2020
    Publication date: October 15, 2020
    Applicant: Abbott Laboratories
    Inventors: Yousef F. Alkhatib, Jay Reimer, Paul E. Ashworth, Keith T. High, Richard Kaleta, Ryan Finn
  • Publication number: 20200323890
    Abstract: The general inventive concepts are directed to compositions and methods for the prevention and treatment of dehydration. Provided herein are nutritional compositions including oral rehydration compositions. Certain embodiments of the nutritional compositions have an acidic pH, and comprise a digestible carbohydrate, sodium, citrate, and an oligosaccharide selected from a fucosylated oligosaccharide and an N-acetylated oligosaccharide.
    Type: Application
    Filed: June 29, 2020
    Publication date: October 15, 2020
    Applicant: ABBOTT LABORATORIES
    Inventors: JOMAY CHOW, PEDRO PRIETO, NED MCCOY
  • Patent number: 10794814
    Abstract: The present disclosure includes provides methods for analyzing biological samples to identify, classify, and/or quantify platelets in the sample. The present disclosure also provides systems and methods for analyzing a blood sample to determine presence of platelet clumps in the sample. Also provided are systems configured for performing the disclosed methods and computer readable medium storing instructions for performing steps of the disclosed methods.
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: October 6, 2020
    Assignee: Abbott Laboratories
    Inventor: Martin Krockenberger
  • Patent number: 10792294
    Abstract: A method for enhancing an individual's mucosal innate immune response to pathogens is disclosed. The method includes a step of administering a nutritional composition to the individual. The nutritional composition includes about 0.05 to about 0.5 mg/mL 2?-fucosyllactose (2?-FL), about 0.05 to about 0.5 mg/mL lacto-N-neotetraose (LNnT), or a combination of both. Also disclosed is a method for enhancing an individual's mucosal innate immune detection of pathogens. The method includes a step of administering a nutritional composition to the individual. The nutritional composition includes a neutral human milk oligosaccharide.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: October 6, 2020
    Assignee: ABBOTT LABORATORIES
    Inventors: Rachael Buck, Geralyn Duska-McEwen, Steven Davis
  • Patent number: 10779550
    Abstract: A nutritional composition comprising at least one human milk oligosaccharide selected from 6? sialyllactose, lacto-N-neotetraose, lacto-N-tetraose, disialylated lacto-N-tetraose, 3?-fucosyllactose, and 3?-sialyllactose. The nutritional composition is used in a method of reducing stress in an individual in need thereof.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: September 22, 2020
    Assignee: ABBOTT LABORATORIES
    Inventors: Jomay Chow, Matthew Panasevich
  • Patent number: 10775399
    Abstract: Example automated storage modules for analyzer liquids are described herein. An example apparatus includes a refrigerated storage module having a plurality of shelves (to store a plurality of carriers) and a loading bay having an array of slots to receive one or more of the carriers. The loading bay is accessible by a user for manual loading or unloading of the carriers. The example apparatus includes a first carrier transporter coupled to the storage module to transfer the carriers between the shelves and a first transfer location and a second carrier transporter movable along a track connecting the storage module to an automated diagnostic analyzer. The second carrier transporter is to transfer a first carrier between the first transfer location and a slot in the loading bay and a second carrier between the first transfer location and a second transfer location accessible by the automated diagnostic analyzer.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: September 15, 2020
    Assignee: Abbott Laboratories
    Inventors: Razvan Raicu, Robert P. Luoma, II
  • Patent number: 10772889
    Abstract: A liquid nutritional composition including 5-methyltetrahydrofolic acid (5-MTHF) is provided. The liquid nutritional composition also includes ascorbic acid and a protein system containing methionine to inhibit or reduce oxidation of the 5-MTHF and provide an active folate level of the liquid nutritional composition that remains stable over the shelf life of the liquid nutritional composition.
    Type: Grant
    Filed: December 19, 2016
    Date of Patent: September 15, 2020
    Assignee: ABBOTT LABORATORIES
    Inventors: Paul Johns, Jeffrey Baxter, Megan Terp, Normanella Dewille, Youngsuk Heo
  • Patent number: 10774359
    Abstract: Herein is provided a simple, reliable and accurate method for cellular analysis on hematology analyzers. In various aspects, the methods provide separation and/or differentiation between red blood cells (RBCs) and white blood cells (WBCs) by utilizing a fluorescent dye to selectively stain WBCs such that they emit stronger fluorescence signals. The method provides optimal detection limits on WBCs and RBCs, thereby allowing analysis of samples with sparse cellular concentrations. As few as one reagent may be used to prepare a single dilution for body fluid analysis, in order to simplify the body fluid analysis. Minimal damage to WBCs is attained using the lysis-free approach described in aspects of the disclosure.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: September 15, 2020
    Assignee: Abbott Laboratories
    Inventors: Jiong Wu, Emily H. Lin, Jihping Yang
  • Patent number: 10775379
    Abstract: Aspects of the invention include WBC analysis reagents, systems and methods that can be used for analyzing a sample of whole blood to identify, classify, and/or quantify white blood cells (WBC) and WBC sub-populations in the sample. The WBC analysis reagents of the present disclosure generally include at least one membrane-permeable fluorescent dye, a WBC protecting reagent, and a surfactant. In some embodiments, the WBC reagents include a suitable amount of an osmolality adjusting component to adjust the osmolality of the WBC reagent into a desired range.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: September 15, 2020
    Assignee: Abbott Laboratories
    Inventor: Jiong Wu
  • Patent number: 10775388
    Abstract: This disclosure provides a robust, sensitive, and specific assay for the detection and measurement of periostin levels in samples obtained from human patients having, or suspected of having an IL-13-mediated disease or disorder. The disclosure further provides novel antiperiostin monoclonal antibodies that recognize at least isoforms 1, 2, 3, 4, 7, and 8 of human periostin, and assay kits comprising one or more of these antibodies.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: September 15, 2020
    Assignees: MEDIMMUNE, LLC, ABBOTT LABORATORIES
    Inventors: Partha S. Chowdhury, Reena Varkey, Meina Liang, Yen-Wah Lee, Katie Streicher, Koustubh Ranade, Ethan Grant, Lydia Greenlees, Yihong Yao, Melissa Parker, Gerard Davis, Nicolette Jeanblanc, Susan Brophy, Bruce Dille
  • Patent number: 10775398
    Abstract: Example automated diagnostic analyzers and methods for using the same are disclosed herein. An example apparatus described herein includes a first carousel rotatably coupled to a base and having a first axis of rotation. The example apparatus includes a second carousel rotatably coupled to the base and vertically spaced over the first carousel such that at least a portion of the second carousel is disposed over the first carousel. In the example apparatus, the second carousel has a second axis of rotation and a plurality of vessels. The example apparatus also includes a pipetting mechanism offset from the second axis of rotation. The example pipetting mechanism is to access the first carousel and the second carousel.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: September 15, 2020
    Assignees: ABBOTT LABORATORIES, CANON MEDICAL SYSTEMS CORPORATION
    Inventors: Brian L. Ochranek, David C. Arnquist, Takehiko Oonuma, Hirotoshi Tahara, Naoto Sato
  • Patent number: 10760939
    Abstract: Liquid level sensing apparatus and related methods are disclosed. An example method includes moving a cannula to pierce a seal of a container to provide access to a liquid in a cavity of the container; moving a probe through a passageway of the cannula and into the cavity of the container; and when the probe is at least partially positioned in the cannula: providing a first signal to the probe to cause the probe to emit a first electrical field; and providing a second signal to the cannula to cause the cannula to emit a second electrical field.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: September 1, 2020
    Assignee: ABBOTT LABORATORIES
    Inventors: Lyle Yarnell, Michael Shawn Murphy
  • Publication number: 20200256843
    Abstract: Methods, devices, and systems for analyte analysis using a nanopore are disclosed. The methods, devices, and systems utilize a first and a second binding member that each specifically bind to an analyte in a biological sample. The method further includes detecting and/or counting a cleavable tag attached to the second binding member and correlating the presence and/or the number of tags to presence and/or concentration of the analyte. Certain aspects of the methods do not involve a tag, rather the second binding member may be directly detected/quantitated. The detecting and/or counting may be performed by translocating the tag/second binding member through a nanopore. Devices and systems that are programmed to carry out the disclosed methods are also provided.
    Type: Application
    Filed: May 1, 2020
    Publication date: August 13, 2020
    Applicant: ABBOTT LABORATORIES
    Inventors: Jeffrey B. Huff, Mark A. Hayden, Peter J. Karabatsos, Andrew S. Schapals, Anthony S. Muerhoff, M. Felicia Bogdan, Thomas Leary, Shelley R. Holets-McCormack, Sophie Laurenson, Andrew T. Fischer, Richard Haack, Stefan Hershberger, Dustin House, Lei Qiao, M. Shawn Murphy, Mark R. Pope, Edna M. Prieto-Ballengee, QiaoQiao Ruan, Pathik Soni, Sergey Tetin, Lyle Yarnell
  • Publication number: 20200230162
    Abstract: Disclosed is a nutritional composition for use in modulating or reducing inflammation in an adult or elderly individual in need thereof. In some aspects, the nutritional composition comprises a neutral human milk oligosaccharide.
    Type: Application
    Filed: April 2, 2020
    Publication date: July 23, 2020
    Applicant: ABBOTT LABORATORIES
    Inventors: GERALYN DUSKA-MCEWEN, SARAH COMSTOCK, SHARON DONOVAN, RACHAEL BUCK, JOSEPH SCHALLER
  • Patent number: 10709720
    Abstract: Disclosed are nutritional compositions including human milk oligosaccharides that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: July 14, 2020
    Assignee: Abbott Laboratories
    Inventors: Rachael Buck, Geralyn O. Duska-McEwen, Joseph P. Schaller
  • Patent number: 10702496
    Abstract: Disclosed are methods of using nutritional compositions generally, and infant formulas specifically, to improve cognitive, brain and/or central nervous system development in an individual. The nutritional compositions include a combination of RRR-alpha tocopherol acetate, non-RRR-alpha-tocopherol stereoisomers, fat, and protein. The amount of non-RRR alpha tocopherol stereoisomers in the nutritional compositions is limited.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: July 7, 2020
    Assignee: ABBOTT LABORATORIES
    Inventors: Chron-si Lai, Matthew Kuchan
  • Publication number: 20200205456
    Abstract: Nutritional tablets and methods of making nutritional tablets are provided. The nutritional tablets include a compressed nutritional powder that includes protein, carbohydrate, fat, and 0.15% to 6% by weight of a flow agent based on the weight of the nutritional tablet. The nutritional tablet has a hardness of no more than 14 N and a surface polarity of greater than 30.5%.
    Type: Application
    Filed: July 24, 2018
    Publication date: July 2, 2020
    Applicant: ABBOTT LABORATORIES
    Inventors: NECLA EREN, TIMOTHY LAPLANTE, DOUGLAS WEARLY, NALINI PATEL
  • Patent number: 10695358
    Abstract: The general inventive concepts are directed to compositions and methods for the prevention and treatment of dehydration. Provided herein are nutritional compositions including oral rehydration compositions. Certain embodiments of the nutritional compositions have an acidic pH, and comprise a digestible carbohydrate, sodium, citrate, and an oligosaccharide selected from a fucosylated oligosaccharide and an N-acetylated oligosaccharide.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: June 30, 2020
    Assignee: ABBOTT LABORATORIES
    Inventors: Jomay Chow, Pedro Prieto, Ned McCoy
  • Publication number: 20200198859
    Abstract: A container (210) for holding granular or powdered material and formed by a top wall (212), a bottom wall (214), a front wall (216), a rear wall (218), a first side wall (220), and a second side wall (222). A rotatably removable lid (D) is interiorly mounted with a scoop (32) and is pivotally hinged to a collar (300) that includes a sealing gasket (330). The collar (300) mounts to the walls of the container (210). A sealing wall 240 of the lid (D) cooperates with the gasket 300 to prevent the contents from spilling. The container (210) incorporates powder control features, a container wall junction (50) preferred geometry and congruent scoop (32) enabling convenient access to the contents, a tolerance variation accommodating and strength improving, J-shaped collar (300) and interlocking indentations (290) and flex clips (310), and a pressure controlling portion (350) that prevents unwanted deformation due to pressure differentials.
    Type: Application
    Filed: March 2, 2020
    Publication date: June 25, 2020
    Applicant: ABBOTT LABORATORIES
    Inventors: JAMES P. PERRY, CRAIG A. MCCARDELL, JEREMY MCBROOM, DAVID COMPEAU, ASHLEY A. GOHLKE, WILLIAM J. HOOK, KATHERINE J. JORDAN, FRANK S. WALCZAK, PETER B. CLARKE, J. KEVIN CLAY, RICHARD C. DARR, JACK E. ELDER, MARC A. PEDMO, CHARLES R. SCHOTTHOEFER
  • Patent number: D892350
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: August 4, 2020
    Assignee: Abbott Laboratories
    Inventor: Robert Paul Luoma, II