Patents Assigned to Abbott Laboratories
  • Publication number: 20200078385
    Abstract: Disclosed are methods of reducing the incidence of necrotizing enterocolitis in an infant, toddler, or child using nutritional compositions including human milk oligosaccharides. The nutritional compositions including the human milk oligosaccharides are effective in reducing inflammation and the incidence of inflammatory diseases.
    Type: Application
    Filed: November 11, 2019
    Publication date: March 12, 2020
    Applicant: ABBOTT LABORATORIES
    Inventors: JoMay Chow, Steven R. Davis, Rachael Buck, Geralyn O. Duska-McEwen, Hawley K. Linke
  • Patent number: 10583969
    Abstract: A container (210) for holding granular or powdered material and formed by a top wall (212), a bottom wall (214), a front wall (216), a rear wall (218), a first side wall (220), and a second side wall (222). A rotatably removable lid (D) is interiorly mounted with a scoop (32) and is pivotally hinged to a collar (300) that includes a sealing gasket (330). The collar (300) mounts to the walls of the container (210). A sealing wall 240 of the lid (D) cooperates with the gasket 300 to prevent the contents from spilling. The container (210) incorporates powder control features, a container wall junction (50) preferred geometry and congruent scoop (32) enabling convenient access to the contents, a tolerance variation accommodating and strength improving, J-shaped collar (300) and interlocking indentations (290) and flex clips (310), and a pressure controlling portion (350) that prevents unwanted deformation due to pressure differentials.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: March 10, 2020
    Assignee: ABBOTT LABORATORIES
    Inventors: James P. Perry, Craig A. McCardell, Jeremy McBroom, David Compeau, Ashley A. Gohlke, William J. Hook, Katherine J. Jordan, Frank S. Walczak, Peter B. Clarke, J. Kevin Clay, Richard C. Darr, Jack E. Elder, Marc A. Pedmo, Charles R. Schotthoefer
  • Patent number: 10578602
    Abstract: An apparatus for analyzing biologic fluid is provided that includes a first planar member, a second planar member, and at least three separators. At least one of planar members is transparent. The separators are disposed between the members, and separate the members to form a chamber having a height. At least one of the members or separators is sufficiently flexible to permit the chamber height to approximate the mean size of the separators. During use, the biologic fluid to be analyzed is disposed within the chamber.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: March 3, 2020
    Assignee: Abbott Laboratories
    Inventor: Stephen C. Wardlaw
  • Patent number: 10568896
    Abstract: A method for preventing or mitigating an acute allergic response in a subject is disclosed. The method includes a step of administering a nutritional composition to the subject. The nutritional composition includes at least one of an acidic or a neutral HMO, but does not include an N-acetyl-lactosamine.
    Type: Grant
    Filed: November 18, 2014
    Date of Patent: February 25, 2020
    Assignee: Abbott Laboratories
    Inventors: Rachael Buck, Steven Davis, Paul Forsythe
  • Publication number: 20200022996
    Abstract: Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
    Type: Application
    Filed: August 5, 2019
    Publication date: January 23, 2020
    Applicant: ABBOTT LABORATORIES
    Inventors: RACHAEL BUCK, GERALYN O. DUSKA-MCEWEN, JOSEPH P. SCHALLER
  • Patent number: 10533935
    Abstract: Aspects of the present disclosure include methods for detecting events in a flow cytometer. Also provided are methods of detecting cells in a flow cytometer. Other aspects of the present disclosure include methods for determining a level of contamination in a flow cell. Computer-readable media and systems, e.g., for practicing the methods summarized above, are also provided.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: January 14, 2020
    Assignee: Abbott Laboratories
    Inventors: Amish P. Shah, Frederic M. Hulett, III
  • Publication number: 20190381077
    Abstract: Disclosed are methods of modulating and/or decreasing serum corticosterone levels in an individual affected by stress. Further disclosed are methods of modulating the hypothalamic pituitary adrenal response in an individual. The methods include administration of 2-fucosyl-lactose to an individual.
    Type: Application
    Filed: August 30, 2019
    Publication date: December 19, 2019
    Applicant: ABBOTT LABORATORIES
    Inventors: ENRIQUE VAZQUEZ HERNANDEZ, RICARDO RUEDA CABRERA, RACHAEL BUCK, MARIA RAMIREZ GONZALEZ
  • Patent number: 10508983
    Abstract: A method for counting blood cells in a sample of whole blood. The method comprises the steps of: (a) providing a sample of whole blood; (b) depositing the sample of whole blood onto a slide, e.g., a microscope slide; (c) employing a spreader to create a blood smear; (d) allowing the blood smear to dry on the slide; (e) measuring absorption or reflectance of light attributable to the hemoglobin in the red blood cells in the blood smear on the slide; (f) recording a magnified two-dimensional digital image of the area of analysis identified by the measurement in step (e) as being of suitable thickness for analysis; and (g) collecting, analyzing, and storing data from the magnified two-dimensional digital image. Optionally, steps of fixing and staining of blood cells on the slide can be employed in the method.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: December 17, 2019
    Assignee: Abbott Laboratories
    Inventors: Richard G. Kendall, John W. Roche
  • Patent number: 10507019
    Abstract: A suture trimmer including an elongate shaft including an elongate lumen extending proximally from a distal end of the elongate shaft, a transverse through-opening disposed proximal the distal end of the shaft, and a groove extending proximally from the distal end of the shaft to a distal end of the opening. A fitting is disposed within the elongate lumen at the distal end of the shaft and extends distally therefrom. A cutting member is slidably received within the lumen of the shaft and configured to move between a proximal end of the opening and the distal end of the opening and cut a suture disposed within and extending from the opening.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: December 17, 2019
    Assignee: Abbott Laboratories
    Inventors: T. Daniel Gross, Maurice Marthaler, Michael S. Dana, Dawn Ma
  • Patent number: 10501816
    Abstract: Provided herein are compositions, methods, and kits for detecting human Pegivirus 2 (HPgV-2). In certain embodiments, provided herein are HPgV-2 specific nucleic acid probes and primers, and methods for detecting HPgV-2 nucleic acid. In other embodiments, provided herein are HPgV-2 immunogenic composition compositions, methods of treating a subject with immunogenic HPgV-2 peptides, and methods of detecting HPgV-2 subject antibodies in a sample.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: December 10, 2019
    Assignees: ABBOTT LABORATORIES, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Charles Chiu, Deanna Lee, Michael Berg, George Dawson, Kelly Coller, Kevin Cheng, John R. Hackett, Jr., Matthew Frankel, Kenn Forberg
  • Publication number: 20190364939
    Abstract: A pureed nutritional product, a packaged nutritional product containing a pureed nutritional product, and a method of making the pureed nutritional product are provided. The pureed nutritional product includes from 50 wt % to 99.7 wt % of a blend of fruit and vegetable, at least one polyunsaturated fatty acid, at least one carotenoid, and RRR-alpha-tocopherol. The pureed nutritional product has an energy density of 0.4 kcal/g to 0.8 kcal/g. The pureed nutritional product has desirable consistency, texture, and mouthfeel characteristics.
    Type: Application
    Filed: September 21, 2017
    Publication date: December 5, 2019
    Applicant: ABBOTT LABORATORIES
    Inventors: ROCKENDRA GUPTA, GAURAV PATEL, NORMANELLA DEWILLE
  • Patent number: 10488362
    Abstract: Example paper substrate diagnostic apparatus and related methods and systems are disclosed herein. An example apparatus includes a hydrophobic substrate having a first end and a second end opposite the first end. The apparatus includes a detection zone on a first surface of the substrate, the detection zone defining an area to sense an analyte in a sample, the detection zone comprising a first electrode and a second electrode disposed on the first surface of the substrate and a layer of hydrophilic ink disposed on the two electrodes and an area between the first and second electrodes. The apparatus also includes a channel comprising hydrophilic ink disposed on the first surface of the substrate, the channel having an inlet section adjacent the first end of the substrate, a middle section, and an outlet section in contact with the layer of hydrophilic ink. The channel is to transfer a fluid sample from the inlet section to the layer of hydrophilic ink.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: November 26, 2019
    Assignee: ABBOTT LABORATORIES
    Inventor: Sophie Laurenson
  • Patent number: 10481072
    Abstract: Systems and methods for analyzing blood samples, and more specifically for performing a nucleated red blood cell (nRBC) analysis. The systems and methods screen a blood sample by means of fluorescence staining and a fluorescence triggering strategy, to identify nuclei-containing particles within the blood sample. As such, interference from unlysed red blood cells (RBCs) and fragments of lysed RBCs is substantially eliminated. The systems and methods also enable development of relatively milder reagent(s), suitable for assays of samples containing fragile white blood cells (WBCs). In one embodiment, the systems and methods include: (a) staining a blood sample with an exclusive cell membrane permeable fluorescent dye; (b) using a fluorescence trigger to screen the blood sample for nuclei-containing particles; and (c) using measurements of light scatter and fluorescence emission to distinguish nRBCs from WBCs.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: November 19, 2019
    Assignee: Abbott Laboratories
    Inventors: Jiong Wu, Marilou Coleman, Emily H. Lin, Michael R. Buhl, Giacomo Vacca
  • Patent number: 10481071
    Abstract: Systems and methods for analyzing blood samples, and more specifically for performing a white blood cell (WBC) differential analysis. The systems and methods screen WBCs by means of fluorescence staining and a fluorescence triggering strategy. As such, interference from unlyzed red blood cells (RBCs) and fragments of lysed RBCs is substantially eliminated. The systems and methods also enable development of relatively milder WBC reagent(s), suitable for assays of samples containing fragile WBCs. In one embodiment, the systems and methods include: (a) staining a blood sample with an exclusive cell membrane permeable fluorescent dye, which corresponds in emission spectrum to an excitation source of a hematology instrument; (b) using a fluorescence trigger to screen the blood sample for WBCs; and (c) using measurements of (1) axial light loss, (2) intermediate angle scatter, (3) 90° polarized side scatter, (4) 90° depolarized side scatter, and (5) fluorescence emission to perform a differentiation analysis.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: November 19, 2019
    Assignee: Abbott Laboratories
    Inventors: Jiong Wu, Giacomo Vacca
  • Patent number: D868284
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: November 26, 2019
    Assignee: ABBOTT LABORATORIES
    Inventors: Kyle Demmink, Jeremy McBroom
  • Patent number: D869276
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: December 10, 2019
    Assignee: Abbott Laboratories
    Inventor: Roger W. Accurso
  • Patent number: D869309
    Type: Grant
    Filed: October 17, 2017
    Date of Patent: December 10, 2019
    Assignee: ABBOTT LABORATORIES
    Inventors: Christina A. Barton, Sherry Sue Eckholm, Vladlena Belozerova, Ami Marie Verhalen, Jesse Charles Darley
  • Patent number: D875269
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: February 11, 2020
    Assignee: Abbott Laboratories
    Inventor: Robert Paul Luoma, II
  • Patent number: D875270
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: February 11, 2020
    Assignee: Abbott Laboratories
    Inventors: Robert Paul Luoma, II, Brian Ochranek, Cheryl L. Davidson, Bradley Weston
  • Patent number: D876259
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: February 25, 2020
    Assignee: Abbott Laboratories
    Inventors: Christina A. Barton, Vladlena Belozerova, Ami Marie Verhalen, Jesse Charles Darley, Sherry Sue Eckholm