Patents Assigned to Advanced Custom Engineered Systems & Equipment Inc.
  • HOSE REEL SYSTEM
    Publication number: 20250145407
    Abstract: In accordance with example embodiments a hose reel system including a layout guide is provided.
    Type: Application
    Filed: January 10, 2025
    Publication date: May 8, 2025
    Inventor: Mick Zoske
  • PYRAZOLOPYRIMIDINES, COMPOSITIONS COMPRISING THEM AND USES THEREOF
    Publication number: 20250145628
    Abstract: The present document relates to pyrazolopyrimidine compounds, pharmaceutical compositions comprising the same and their use in the treatment or prevention of diseases and disorders associated with the cannabinoid CB1 receptor. For example, the pyrazolopyrimidine compounds, or a tautomeric form and/or salt thereof, are of Formula I: Formula I wherein R1 to R4 are as defined herein.
    Type: Application
    Filed: February 2, 2023
    Publication date: May 8, 2025
    Inventors: Jeremy Green, Shawn Gallagher-Duval, Alexandre Lemire, Yuchen Zhou, Hong Wang
  • PHARMACEUTICAL COMPOSITIONS FOR IMAGING, DIAGNOSIS AND TREATMENT OF CANCER
    Publication number: 20250145664
    Abstract: The present invention relates to a pharmaceutical cold kit composition comprising a chelating agent linked to somatostatin receptor binding organic moiety, a stabilizer, a buffer, and a caking agent or bulking agent, wherein the composition is free of sequestering agent. Further, the present invention also relates to the process of preparing reconstituted or radiolabeled solution composition having high in use stability and radiochemical purity and use thereof for diagnostic and/or therapeutic purposes.
    Type: Application
    Filed: January 14, 2025
    Publication date: May 8, 2025
    Inventors: Vijayaraj Kuniyil Kulangara, Riadh Zriba, Tusharmouli Mukherjee, Indranil Nandi, Miriam Ruiz Pena
  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF HEPATITIS B INFECTION
    Publication number: 20250145669
    Abstract: Disclosed herein are compositions and methods for the treatment of hepatitis B infection, including chronic hepatitis B (CHB).
    Type: Application
    Filed: December 10, 2024
    Publication date: May 8, 2025
    Applicant: MELBOURNE HEALTH
    Inventors: Renae Walsh, Stephen Locarnini, Hans Netter, Ronald Farquhar
  • BISPECIFIC ANTIBODY AND APPLICATION THEREOF
    Publication number: 20250145701
    Abstract: A VEGF-targeting VHH, a bispecific antibody targeting PD-1 and VEGF developed on the basis of the VHH, and an application thereof. The VHH has high stability, and has a plurality of excellent effects, such as ease of expression and purification. The constructed bispecific antibody targeting PD-1 and VEGF has high stability, can target enrichment in a high-expression VEGF tumor region, has good medicinal efficacy and safety, and has excellent treatment potential.
    Type: Application
    Filed: December 29, 2023
    Publication date: May 8, 2025
    Inventors: Dong LI, Jianmin FANG, Mei YUAN, Shanshan CHEN, Sisi WANG, Yinghao XIN, Yuanhao LI, Guorui ZHAO, Xinting MA
  • GPRC5D ANTIBODY AND APPLICATION THEREOF
    Publication number: 20250145705
    Abstract: The present invention relates to an antibody against G protein coupled receptor C5 family subtype D (GPRC5D) and an application of the antibody. Specifically, disclosed are an antibody specifically binding to GPRC5D or an antigen-binding fragment thereof, and an encoding nucleic acid thereof, an expression vector and an expression cell, a preparation method, a pharmaceutical composition, and a use thereof in the preparation of a pharmaceutical composition for treating diseases, for example, a use in treating tumors. The present invention has important significance for the development of GPRC5D antibody treatment drugs and detection reagents.
    Type: Application
    Filed: December 30, 2022
    Publication date: May 8, 2025
    Inventors: Yayuan FU, Jingli LIAO, Bowei YIN, Zhuoxiao CAO, Renhong TANG, Jinsheng REN
  • PROTEINS COMPRISING CD3 ANTIGEN BINDING DOMAINS AND USES THEREOF
    Publication number: 20250145711
    Abstract: The disclosure provides antigen binding domains that bind cluster of differentiation 3 (CD3) protein, comprising the antigen binding domains that bind CD3?, polynucleotides encoding them, vectors, host cells, methods of making and using them.
    Type: Application
    Filed: September 10, 2024
    Publication date: May 8, 2025
    Inventors: Adam Zwolak, Raymond Brittingham, Scott R. Brodeur, Rajkumar Ganesan, Sherry Lynn La Porte, Jinquan Luo, Fang Yi, Colleen M. Kane, Triveni K. Bhatt
  • TREATMENT OF RENAL CELL CARCINOMA
    Publication number: 20250145712
    Abstract: This disclosure provides methods for treating a subject afflicted with a tumor derived from a renal cell carcinoma. The methods comprise administering a first dose to a subject of an anti-PD-1 antibody or antigen-binding portion thereof and/or an anti-PD-L1 antibody or antigen-binding portion thereof, and administering a second dose to the subject, wherein the subject exhibited differential expression in one or more biomarker genes, e.g., CTLA-4, TIGIT, and/or PD-L2, following administration of the first dose.
    Type: Application
    Filed: October 15, 2024
    Publication date: May 8, 2025
    Applicant: Bristol-Myers Squibb Company
    Inventors: Jason Samuel SIMON, Petra B. ROSS-MACDONALD
  • COMPOSITIONS OF HFO-1234YF, HFO-1132E, AND HYDROCARBONS AND SYSTEMS FOR USING THE COMPOSITIONS
    Publication number: 20250145875
    Abstract: Environmentally friendly refrigerant blends utilizing refrigerants including 2,3,3,3-tetrafluoropropene (HFO-1234yf), 1,2-difluoroethylene, at least one hydrocarbon selected from the group consisting of propane, cyclopropane, propylene, isobutane, and n-butane, and optionally 1,1-difluoroethane (HFC-152a). The blends have low GWP, low toxicity, and low flammability with low temperature glide for use in a hybrid, mild hybrid, plug-in hybrid, or full electric vehicles for thermal management (transferring heat from one part of the vehicle to the other) of the passenger compartment providing air conditioning (A/C) or heating to the passenger cabin.
    Type: Application
    Filed: February 24, 2023
    Publication date: May 8, 2025
    Applicant: THE CHEMOURS COMPANY FC, LLC
    Inventors: JASON R. JUHASZ, DAVID MATTHEW SNYDER, LUKE DAVID SIMONI, SIDDARTH SITAMRAJU
  • WATERTIGHT COMPOSITE STRAIGHT WALL POST-TENSIONED CONCRETE TANK STRUCTURE AND METHODS FOR MAKING OR USING SAME
    Publication number: 20250146318
    Abstract: The subject invention pertains to composite straight wall liquid storage tanks held in persistent compression to provide superior watertightness for the life of the tank, including ACI American Concrete Institute 350 code-compliant liquid-containing composite straight wall structures with an integral full-height galvanized steel shell diaphragm fully encased in continuous shotcrete. The provided tapered composite straight wall can incorporate epoxy-bonded diaphragm sheet joints at the floor, wall, L-shaped corner posts, and T-shaped bisecting wall junction plates to support watertight connections. The external envelope and, optionally, one or more internal or bisecting walls of the structure can be provided in persistent compression by compressive post-tensioning.
    Type: Application
    Filed: June 13, 2024
    Publication date: May 8, 2025
    Inventor: Robert G. OYENARTE
  • HEAT UTILIZATION SYSTEM AND HEAT GENERATING DEVICE
    Publication number: 20250146715
    Abstract: A heat utilization system includes: a heat generating device of one aspect of the invention, includes: a heat generating device including a heat-generating element configured of a multilayer film for generating heat by occlusion and discharge of hydrogen, a heating unit for heating the heat-generating element, and a sealed container for containing the heat-generating element and the heating unit; and a heat utilization device for utilizing a heat medium heated by the heat generating device as a heat source. The heat generating device is configured to be attachable and detachable with respect to the heat utilization device.
    Type: Application
    Filed: December 13, 2022
    Publication date: May 8, 2025
    Applicant: CLEAN PLANET INC.
    Inventors: Yoshito Endo, Yasuhiro Iwamura, Takehiko Itoh, Hideki Yoshino
  • TEMPERATURE ADJUSTMENT APPARATUS AND SENSING SYSTEM
    Publication number: 20250146723
    Abstract: Provided is a temperature adjustment apparatus that performs thermal exchange with one or more objects by means of cooling water, the temperature adjustment apparatus comprising a distribution portion including a distribution channel through which the cooling water is distributed and a sensing system that senses a state of the distribution channel, wherein the sensing system includes a pressure sensor provided at at least one position in the distribution channel, that senses pressure of the cooling water and a sensing unit that senses a state of the distribution channel based on the pressure sensed by the pressure sensor.
    Type: Application
    Filed: September 24, 2024
    Publication date: May 8, 2025
    Inventors: Hiroto KIKUCHI, Katsuyuki UEMATSU
  • METHOD AND SYSTEM FOR DIAGNOSING RETENTION CIRCUIT
    Publication number: 20250147119
    Abstract: The present disclosure provides a retention circuit diagnostic system. The retention circuit diagnostic system includes a first retention circuit configured to output a retention signal for controlling a contactor, and a controller configured to transmit a first signal related to a state control of the contactor, and to transmit a second signal for activating the first retention circuit, and configured to diagnose the first retention circuit based on the retention signal.
    Type: Application
    Filed: March 28, 2024
    Publication date: May 8, 2025
    Inventor: Hyunjun KIM
  • ELECTRONIC COMPONENT TRANSFER SYSTEM
    Publication number: 20250147124
    Abstract: A position detection sensor is provided on an index table, and a load track drive unit is provided on a load track. A control unit controls the load track drive unit to radially move the load track to adjust a radial position of the pocket with respect to the load track, based on a signal from the position detection sensor. The object is to smoothly fill electronic components stored in a load track into pockets in an index table.
    Type: Application
    Filed: November 7, 2024
    Publication date: May 8, 2025
    Applicant: TOKYO WELD CO., LTD.
    Inventors: Shunsuke SASAKI, Hiroki OHNISHI, Taiyo KOMORI, Rintaro TAKAGI, Haruka TOOYAMA, Yoshikazu SASAOKA
  • SYSTEM AND METHOD FOR SEGMENTED FREQUENCY DOMAIN CORRELATION WITH DOPPLER BINNING
    Publication number: 20250147149
    Abstract: A communication system in a mobile platform receives a signal and applies a plurality of Doppler offsets within a range of potential Doppler offsets. Spectral analysis is performed for correlators in each of the Doppler offset signals, and a signal with a best correlation score is used to identify the actual Doppler offset of the signal. The signal is padded by some predetermined length and correlators are segmented. A polynomial interpolator corrects the sample rate for each one of the Doppler offsets signals.
    Type: Application
    Filed: November 7, 2023
    Publication date: May 8, 2025
    Inventor: Ryan M. Murphy
  • LED AND LASER DIODE COMBINED ILLUMINATION SYSTEM
    Publication number: 20250147216
    Abstract: The combined illumination system includes a first waveguide and a second waveguide. An output end of the first waveguide is coupled to an input end of the second waveguide. An LED light source is configured to emit light from an input end of the first waveguide and through the output end of the second waveguide to illuminate a workpiece. A laser light source is coupled to an input end of an optical fiber, and an output end of the optical fiber is coupled to the input end of the second waveguide. The laser light source is configured to emit laser light from the input end of the optical fiber through the output end of the second waveguide to illuminate the workpiece.
    Type: Application
    Filed: December 28, 2023
    Publication date: May 8, 2025
    Inventors: Tal Goichman, Ronen Yogev, Assaf Hacohen, Ilia Lutsker
  • ROUTE PLANNING SYSTEM FOR AUTONOMOUS AGRICULTURAL WORK MACHINES
    Publication number: 20250147519
    Abstract: A route planning system configured to create the route plan for an autonomous agricultural work machine and/or for a network of autonomous agricultural work machines. A given agricultural work machine may be operated in a semi-autonomous operating mode, in which a user is on board or resident in the agricultural work machine, or a fully autonomous operating mode, in which no user is assigned to the agricultural work machine. The generated route plan may be dynamically adapted depending on one or more events, with the dynamically adapted route plan being transmitted to the autonomous agricultural work machine. The user or an operator assigned to the given autonomous agricultural work machine may accept the adapted route plan for the given agricultural work machine.
    Type: Application
    Filed: November 8, 2024
    Publication date: May 8, 2025
    Applicant: CLAAS KGaA mbH
    Inventors: Thijs Verploegen, Stefan Peters, Josef Fischer, Jan Carsten Wieckhorst, Jannik Redenius, Axel Schröder, Felix Hülsmann, Robin Monkenbusch
  • ILLUMINATED TOUCHPAD
    Publication number: 20250147627
    Abstract: Disclosed are an illuminated touchpad including a protection layer, a touch module, and a Parallax-Barrier light source module. The touch module is disposed between the protection layer and the Parallax-Barrier light source module. The Parallax-Barrier light source module has a Parallax-Barrier pattern or is used to produce the Parallax-Barrier pattern. The Parallax-Barrier light source module further has multiple patterns and produces multiple illuminated patterns by the patterns, or the Parallax-Barrier light source module directly produces the illuminated patterns. By the Parallax-Barrier pattern, lights of the illuminated patterns pass through the touch module and the protection layer to form multiple stereoscopic images.
    Type: Application
    Filed: January 19, 2024
    Publication date: May 8, 2025
    Applicant: Acer Incorporated
    Inventors: Yi-Jung Chiu, Wei-Kuo Shih
  • DATA MIRRORING FOR A VIRTUAL ENVIRONMENT
    Publication number: 20250147710
    Abstract: Methods, apparatus, and non-transitory machine-readable media associated with mirroring data for a virtual environment. An apparatus can include a memory device and a processor communicatively coupled to the memory device. The processor can receive data for display from a different apparatus that is coupled to the apparatus, wherein the different apparatus is a physical apparatus. The processor can modify image data for a virtual environment using the data. A display system coupled to the processor can display the modified image data of the virtual environment to mirror the data from the different apparatus to the virtual environment.
    Type: Application
    Filed: November 2, 2023
    Publication date: May 8, 2025
    Inventors: John D. Hopkins, Mohad Baboli
  • MULTIPLE REGISTER ALLOCATION SIZES FOR GPU HARDWARE THREADS
    Publication number: 20250147762
    Abstract: Described herein is a graphics processor having processing resources with configurable thread and register configurations. Program code can configure a number of registers and accumulators that will be used by hardware threads during execution of the program code by the graphics processor. Processing resources within the graphics processor can be configured to assign different numbers of registers and accumulators to hardware threads based on the configuration requested by program code to be executed by the processing resource.
    Type: Application
    Filed: November 8, 2023
    Publication date: May 8, 2025
    Applicant: Intel Corporation
    Inventors: Vasanth Ranganathan, Gang Chen, Supratim Pal, Jorge Eduardo Parra Osorio, Arthur Hunter, Boris Kuznetsov, Deepak N K, Siva Kumar Seemakurthi, James Valerio, Shubham Dinesh Chavan, Abhishek Kumar Singh, Samir Pandya, Sandeep Tippannanavar Niranjan, Alan Curtis, Jain Philip, Maltesh Kulkarni, Fangwen Fu, John Wiegert, Brent Schwartz