Abstract: The present invention provides a silk fibroin-based hydrogel and antibiotic composition consists of 5% silk fibroin embedded with 0.4-2% antibiotic, more specifically, tetracycline or doxycycline, and the antibiotic used to prepare the silk fibroin-based hydrogel is super saturated solution, i.e., 100% concentration of antibiotic in de-ionized water. The invention also provides a method to prepare silk fibroin-based hydrogel and antibiotic composition comprising steps of: preparing 5% silk fibroin solution and maintaining at 16-21° C.; adding saturated antibiotic solution in the silk fibroin solution to form silk fibroin-based hydrogel; stabilizing the hydrogel at 16-21° C.; and lyophilising the stabilized hydrogel at 4-6° C. to form a dry hydrogel silk fibroin matrix with drug embedded in it. Further, the invention provides composition of the drug-silk fibroin-based hydrogel formulation and method for using it for wound healing of tooth extraction socket.

Abstract: This disclosure provides HIV immunogens and use thereof for generating an immune response in a subject. Also disclosed is a method of isolating anti-HIV antibodies and use thereof. This disclosure further provides a method for treating or preventing a human immunodeficiency type 1 (HIV-1) infection in a subject using the disclosed HIV immunogens and/or antibodies.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: Embodiments of a wearable device are provided. The wearable device comprises a reusable component and a disposable component. The disposable component comprises a patient engagement substrate comprising adhesive on a bottom side, an electrode on the bottom side, a disposable component electrical connector, and a disposable component mechanical connector. The reusable component comprises a plurality of sealed housings mechanically coupled to each other and movable with respect to each other, each of the plurality of housings containing one or more of a capacitor and a controller, a reusable component mechanical connector adapted to removably connect to the disposable component mechanical connector, and a reusable component electrical connector adapted to removably connect to the disposable component electrical connector. The device can comprise a cardiopulmonary physiologic monitor or an automatic external defibrillator, among other types of devices.

Abstract: A fire retarding biochemical liquid composition including: a dispersing agent realized in the form of a major amount of water, for dispersing alkali metal ions dissolved in the water; a major amount of a first fire retarding agent realized in the form of a first alkali metal salt of a nonpolymeric saturated carboxylic acid, specifically, tripotassium citrate, for providing metal potassium ions dispersed in the water when the at least one alkali metal salt is dissolved in the water to form a mixed retardant solution; a minor amount of a second fire retarding agent realized in the form of a second alkali metal salt of a nonpolymeric saturated carboxylic acid, specifically, sodium benzoate (SB), for providing metal sodium ions dispersed in the water when the at least one alkali metal salt is dissolved in the mixed retardant solution, for functioning as a secondary fire retardant agent and also inhibiting surface corrosion reactions involving metals contacting the mixed retardant solution, including specific meta

Abstract: Golf club fitting systems can include a golf club head along with multiple alternative adjustment sleeves that each mate with the club head to modify loft and lie angles. Each adjustment sleeve can include a first portion having a respective longitudinal axis and configured to mate and coaxially align with a hosel of the golf club head, and a second portion having a respective longitudinal axis angularly offset from the longitudinal axis of the first portion and configured to mate and coaxially align with a golf club shaft. Each different adjustment sleeve can be configured to alter a position of the golf club head relative to a golf club shaft by a different adjustment value relative to each other. Fitting systems can also include a shaft sleeve that can join any of various different shafts with any of the adjustment sleeves. Fitting systems can also include additional club heads.

Abstract: A method of determining a position for a virtual object is described. A location of a client device is determined, and, based on the determined location a set of map segments is retrieved. A virtual object is determined to be displayed on the client device. Relation vectors between the virtual object and each map segment of the retrieved set of map segments are obtained. Each relation vector is weighted based on object parameters of the virtual object. A position to display the virtual object is determined based on the weighted relation vectors. The virtual object is provided for display on the client device as the determined position.

Abstract: A microfluidic system for performing nucleic acid synthesis includes a microfluidic reactor site. A first reactor site valve is coupled upstream of the reactor site. A second reactor site valve is coupled downstream of the reactor site. The system includes a plurality of microfluidic inlets to couple to multiple pressurized reagent containing chambers. A plurality of reagent valves are coupled to individually control a size of droplets of reagent provided by respective pressurized reagent containing chambers. A pressurized gas source is coupled to propel droplets downstream to the microfluidic reactor site.

Abstract: In biosciences and related fields, it can be useful to study cells in isolation so that cells having unique and desirable properties can be identified within a heterogenous mixture of cells. Processes and methods disclosed herein provide for encapsulating cells within a microfluidic device and assaying the encapsulated cells. Encapsulation can, among othere benefits, facilitate analyses of cells that generate secretions of interest which would otherwise rapidly diffuse away or mix with the secretions of other cells.

Abstract: A coating device comprises a stage, a coater and a dryer. A substrate is configured to be placed on the stage. The coater is configured to eject a coating liquid from a nozzle to form a coating film on the substrate that is placed on the stage while moving relative to the substrate. The dryer is configured to dry the coating film on the substrate. Drying promotion force of the dryer for promoting drying is adjusted on the basis of drying distribution information of the coating film on the substrate in accordance with a region of the coating film.

Abstract: Coated substrates and methods of preparing such coated substrates are described. The method may include introducing an aerosol into a non-thermal plasma, wherein the aerosol comprises at least one organic compound and a first solvent. depositing the at least one organic compound on a surface of a substrate positioned downstream of the plasma to form a coating on the surface. and spraying a second solvent in aerosol form on the coating. the second solvent being the same or different from the first solvent. Spraying the second solvent may increase uniformity of the coating.

Abstract: The present application discloses a microswitch automatic assembly apparatus, microswitch, and assembly method, the microswitch automatic assembly apparatus comprises a base, a material carrying rotary table and an installation disc that are provided on the base, a base loading mechanism, a support installation mechanism, a swing rod installation mechanism, and a tension spring installation mechanism are sequentially provided along a rotation direction of the material carrying rotary table, the tension spring installation mechanism comprises a tension spring pre-installation platform, a tension spring position detection platform, a tension spring installation platform, and a tension spring elasticity detection platform.

Abstract: An adjustable chair can support an occupant that sits on a front portion of a seat cushion. When the user leans back, the chair can provide back support without requiring that the user slide rearwardly along the seat cushion, thereby providing back support to minimize, limit, or substantially eliminate lower back fatigue, discomfort, or the like. A back support of the chair can be located at a desired forward/rearward position based on the user's position on the seat. In some settings, the chair can be used by a card dealer who tends to sit on a forward portion of the seat when dealing cards. The back support can be positioned to comfortably support the dealer's back when, for example, the dealer sits generally upright. The chair can also be used by other individuals that frequently sit on the front of the seat cushion.

Abstract: A gravity-feed dispensing system includes a dispenser having a hopper and a valve. The hopper is configured to hold a bulk material. The valve is configured to selectively connect to the hopper. The valve includes an actuator assembly operable between open and closed conditions to selectively permit bulk material to pass from the hopper through the valve. A fixture includes a shelf configured to support the dispenser. A rail is at the front of the shelf. The dispenser is configured for pivotable engagement with the rail. A latch is configured to releasably retain the dispenser in an operative position on the shelf.

Abstract: A booster seat organizer stand adapted to accommodate a plurality of children's booster seats in a stacked vertical orientation is disclosed. The stand features a flat base with raised walls forming a cavity to securely hold the booster seats. A vertical back panel extends from the rear edge of the base to provide additional support and a pair of side panels extend from side edges of the back panel and has wavy contours to offer lateral stability to the stacked booster seats. The stand can include one or more storage compartments for accessories, a detachable hook for wall mounting, and an additional storage compartment integrated or detachably attached to the base. The stand can be used in homes, daycares, restaurants, and public facilities and enhances safety, convenience, and organization for storing children's booster seats.

Abstract: A portable restroom with a base spaced apart from a ceiling. There are a plurality of walls therebetween that together define an interior of the restroom with one or more toilets. The restroom has at least one door configured to provide ingress into the interior. A plurality of fork tine ports are provided over the door that receive forklift tines for moving the portable restroom by its ceiling.

Abstract: A vehicle including an engine bay and a passenger cabin. The engine bay includes an engine and an HVAC system that is configured to condition the passenger cabin. The HVAC system includes a condenser and a primary fan for drawing ambient air through the condenser; a controller configured to control the HVAC system; at least one sensor in communication with the controller; and at least one auxiliary fan in communication with the controller for drawing air away from the engine bay that has been heated by the engine, wherein based on a signal received from the at least one sensor, the controller is configured to operate the auxiliary fan to draw the air heated by the engine away from the engine bay to minimize the air heated by the engine from intermixing with the ambient air and being circulated through the condenser by the primary fan.

Abstract: An air guide element for a ventilation nozzle in a motor vehicle includes a main body at least partially enclosing the cross-section of the ventilation nozzle and on which air guiding fins are arranged. The air guide element also includes a lighting device. The main body and the air guiding fins are produced as a single piece by multi-component 3D printing. The main body has a transparent core. Portions of the surface of the main body and the air guiding fins are printed onto the core at least partially from a semi-transparent material and at least partially from an opaque material.

Abstract: The present disclosure discloses a cloak bracket for rear bucket of pickup truck including fixed crossbars that are symmetrically provided on a left inner side and a right inner side of the rear bucket. Two fixed crossbars are provided with a first hinge member and a second hinge member on a side of the fixed crossbars along a length direction thereof, respectively. Two second hinge members are hinged with two tail ends of a first arched support bracket, respectively; middle sections on two sides of the first arched support bracket are hinged with a head end of a support arm, respectively; a tail end of the support arm is detachably hinged with the first hinge member. The beneficial effect of the present disclosure is that a detachable characteristic of the support arm can be used to quickly detach the support arm from the first hinge member.

Abstract: A cable storage assembly is provided including a first cable configured to be used outdoors, a second cable configured to be used outdoors and indoors, a connector, an external cable storage reel, and a housing. The external cable storage reel defines a first flange, a second flange, and a first space between the first flange and the second flange. The external cable storage reel is configured to receive the first cable within the first space, and the housing defines an internal volume and includes at least one opening. The housing is configured to receive an extra portion of the first cable within the internal volume. The first cable extends from the first space into the internal volume through the opening(s). The first cable is connected to the second cable within the internal volume using the connector. The second cable is configured to extend from the internal volume through the opening(s).