Abstract: A device for driving a switch in a digital-to-analog converter (DAC) includes first and second latches, and a logic gate. The first latch is configured to store a digital input data signal according to a clock signal, and to output a first latch signal corresponding to the stored digital input data signal. The second latch is configured to store the first latch signal output by the first latch according to a logical inverse of the clock signal, and to output a second latch signal corresponding to the stored first latch signal. The logic gate is configured to perform an OR logic operation on the first latch signal and the second latch signal, the logic gate outputting a drive signal for driving a switch in the DAC connected to a current source.

Abstract: A method is provided for compensating for impairment of an electrical signal output from a device under test (DUT), the impairment resulting from an impairment network. The method includes measuring an impaired electrical signal received at an electronic analyzer via the impairment network; applying a coded pulse sequence to the impairment network; estimating an impairment transfer function corresponding to the impairment based on the applied pulse sequence; and correcting the measured electrical signal using the impairment transfer function to determine the electrical signal output from the DUT.

Abstract: A fluid pumping device includes a piezoelectric actuator externally coupled to a microfluidic device. The piezoelectric actuator has an axial displacement along a lengthwise axis responsive to application of a bias voltage. The axial displacement of the piezoelectric actuator operates one of an internal valve and an internal pump chamber of the microfluidic device.

Abstract: A nuclear magnetic resonance (NMR) probe comprises a superconducting material formed in a spiral having a plurality of fingerlets separated by a plurality of slits, and a normal-metal overlayer formed on the spiral over the plurality of fingerlets and the plurality of slits.

Abstract: A method is provided for compensating for impairment of an electrical signal output from a device under test (DUT), the impairment resulting from an impairment network. The method includes measuring an impaired electrical signal received at an electronic analyzer via the impairment network; applying a stimulus signal to the impairment network; estimating an impairment transfer function corresponding to the impairment based on the applied stimulus signal; and correcting the measured electrical signal using the impairment transfer function to determine the electrical signal output from the DUT.

Abstract: An ionization device comprises: a plasma source configured to generate a plasma. The plasma comprises light, plasma ions and plasma electrons. The plasma source comprises an aperture disposed such that at least part of the light passes through the aperture and is incident on a gas sample. The ionization device further comprises an ionization region; and a plasma deflection device comprising a plurality of electrodes configured to establish an electric field, wherein the electric field substantially prevents the plasma ions from entering the ionization region.

Abstract: A fluid pumping device includes a piezoelectric actuator externally coupled to a microfluidic device. The piezoelectric actuator has an axial displacement along a lengthwise axis responsive to application of a bias voltage. The axial displacement of the piezoelectric actuator operates one of an internal valve and an internal pump chamber of the microfluidic device.

Abstract: A micro-machined frit is provided for use in a chromatography column, having a substrate with a thickness, and holes extending through the thickness and providing fluid communication through the substrate. A micro-machined flow distributor is provided for use in a chromatography column having a substrate, holes extending through the substrate, and channels in fluid communication with the holes. A micro-machined integrated frit and flow distributor device is also provided having a substrate with a thickness, holes extending through the thickness and providing fluid communication therethrough, and channels in fluid communication with at least one of the holes. A chromatography column is provided having a tube, an extraction medium contained therein, and a micro-machined frit positioned proximate an end of the tube. The column can include a micro-machined flow distributor positioned between the frit and the end of the tube.

Abstract: A constant switching current flip-flop includes a latch circuit that provides latch outputs of the flip-flop, whereby the latch outputs are reset to zero at the beginning of each clock cycle to eliminate pattern dependent switching currents. The latch circuit is reset responsive to control signals provided without significant delay.

Abstract: Superficially porous hybrid particles include hybrid solid cores that each contain an inorganic material and an organic material; and porous hybrid outer shells each include the inorganic and organic materials and having ordered pores, wherein the ordered pores have a median pore size ranges from about 15 to about 1000 ? with a pore size distribution (one standard deviation) of no more than 50% of the median pore size and produce at least one X-ray diffraction peak between 0.01° and 10° of a 2? scan range; wherein the particles have a median size range from about 0.5 ?m to about 100 ?m with a particle size distribution (one standard deviation) of no more than 15% of the median particle size, wherein the inorganic material comprises a metal oxide selected from silica, alumina, titania or zirconia.

Abstract: A device for providing a constant mass flow rate to a downstream column system of a gas chromatograph includes a small full scale mass flow controller that controls carrier gas to flow at a first mass flow rate and a flow resistance element, including an inlet port connected to a sample inlet, an outlet port connected to the downstream column system, and a pressure sensing port in fluid communication with the outlet port and the mass flow controller. A sample inlet pressure controller controls the sample inlet at a first pressure, and a pressure sensor measures a second pressure of the carrier gas at the pressure sensing port. A set point of the first pressure is determined as a function of the second pressure, flow resistance of the flow resistance element, and a second mass flow rate from the inlet port to the outlet port of the flow resistance element.

Abstract: Disclosed is a method for determining the quality, expressed in terms of a quality value, of an biomolecule sample, based on measured data of the biomolecule sample, by extracting a number of prescribed features from the measured data using data analysis, and determining the quality value from the extracted features using a quality algorithm.

Abstract: A mass spectrometer having a matrix-assisted laser desorption ionization (MALDI) source which operates at ambient pressure is disclosed.

Abstract: A method of automatically controlling an extendable robot arm to avoid collisions while returning to a first position from a second position includes periodically storing locations of the robot arm as the robot arm moves along a forward path from the first position to the second position; applying heuristic algorithms to the stored locations to determine a return path to the first position, the return path including at least a portion of a retrace path retracing the stored locations of the forward path; and controlling the robot arm to return to the first position using the determined return path.

Abstract: Methods, systems and computer readable storage media for providing image-extracted measurements extracted from an image of at least one cell or subcellular component with the image. At least one attribute is determined from the image-extracted measurement of the at least one cell or sub-cellular component. The image of the at least one cell or sub-cellular component is virtually stained with at least one color, wherein different colors represent different attributes, and wherein the at least one color is virtually stained in locations of the image from where the image-extracted measurements were extracted for the attribute that that color represents.

Abstract: An atmospheric pressure ionization apparatus includes a chamber, an ion inlet structure, an electrode, a sample emitter, and a gas passage. The ion inlet structure includes a sampling orifice. The electrode includes an electrode bore. An ionization region is defined between the ion inlet structure and the electrode. The flared structure is coaxially disposed about the ion inlet structure, and extends along an outward direction that includes a radial component relative to the sampling axis. The sample emitter is oriented at an angle to the sampling axis for directing a sample stream toward the ionization region. The gas passage directs a stream of gas from a gas source to the chamber. The flared structure and the wall cooperatively form an outward-directed portion of the gas passage that extends annularly about the sampling axis and along the outward direction. The gas flows through the outward-directed portion, around the flared structure, and toward the ionization region and the electrode bore.

Abstract: In an example embodiment, the system receives user inputs including: (1) a netlist that describes the circuit elements and connections of an integrated circuit; (2) a mathematical device model that corresponds to the integrated circuit and that includes an equation with a number of parameters and decision variables grouped into terms; and (3) a description of an input voltage. Based on these inputs, the system calculates an output such as a voltage or current. The system displays a GUI that includes a view which shows each of the terms of the equation after a value has been assigned to each parameter and to each decision variable and a view which shows each of the terms of the equation after reduction of the values assigned to each parameter and each decision variable. Upon receipt of a user's change to the value of a parameter, the system promptly updates the views.

Abstract: A mass analyzer comprises a pair of planar electrode structures. The electrode structures are disposed opposite one another, parallel to one another, and axially offset from one another. One of the pair of planar electrodes comprises an opening. The mass analyzer comprises an ion mirror disposed between the pair of planar electrodes. A mass spectrometer and a mass spectrometry method are also described.

Abstract: Methods, systems and computer readable media for controlling an instrument in communication with a host computer are provided. Operations of an instrument that must be completed on schedule are controlled via an embedded controller embedded in the instrument. A complete status packet is sent to a host computer from the embedded controller. Periodically, the embedded controller repeats the sending of a complete status packet to the host computer, wherein status values in the complete status packet are updated with each iteration of sending a complete status packet.