Patents Assigned to Alcon
  • Intraocular irrigating solution having improved flow characteristics
    Patent number: 7084130
    Abstract: Improved intraocular irrigating solutions are described. The solutions have enhanced viscosities that reduce the risk of damage to intraocular surgical procedures by reducing the turbulence of the solutions and dampening the movement of tissue fragments and air bubbles. The solutions preferably also have modified surface tensions that more closely resemble the surface tension of the aqueous humor.
    Type: Grant
    Filed: December 11, 2001
    Date of Patent: August 1, 2006
    Assignee: Alcon, Inc.
    Inventors: Mandar V. Shah, Mikhail Boukhny, William H. Garner, Kerry L. Markwardt, Uday Doshi
  • RNAi inhibition of CTGF for treatment of ocular disorders
    Publication number: 20060166919
    Abstract: RNA interference is provided for inhibition of connective tissue growth factor mRNA expression in ocular disorders involving CTGF expression. Ocular disorders involving aberrant CTGF expression include glaucoma, macular degeneration, diabetic retinopathy, choroidal neovascularization, proliferative vitreoretinopathy and wound healing. Such disorders are treated by administering interfering RNAs of the present invention.
    Type: Application
    Filed: December 19, 2005
    Publication date: July 27, 2006
    Applicant: Alcon, Inc.
    Inventors: Allan Shepard, Iok-Hou Pang
  • Use of ?-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina
    Patent number: 7081482
    Abstract: The invention is directed to the use of ?-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: July 25, 2006
    Assignee: Alcon, Inc.
    Inventors: Robert J. Collier, Jr., Louis Desantis, Jr., Michael A. Kapin
  • Surgical cassette latching mechanism
    Patent number: 7070578
    Abstract: A surgical system having a cassette latching mechanism having two pivoting latching rails. The rails are connected to a rotating latching wheel by spring-loaded latching arms. The latching wheel is connected to a motor by a latching pushbar. The cassette is pressed into the rails which initiates the rotation of the rails, which close onto the cassette. The motor next rotates the latching wheel, producing cam-like movement of the latching arms and thereby further pivoting the latching rails to the fully closed and locked position.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: July 4, 2006
    Assignee: Alcon, Inc.
    Inventors: Kurt D. Leukanech, Daniel J. Wilson
  • Arylaminopropane analogues and their use for the treatment of glaucoma
    Patent number: 7071225
    Abstract: Arylaminopropane analogues are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Grant
    Filed: November 26, 2003
    Date of Patent: July 4, 2006
    Assignee: Alcon, Inc.
    Inventors: Mark R. Hellberg, Abdelmoula Namil
  • Surgical method and apparatus using dual irrigation paths
    Patent number: 7066923
    Abstract: A method of conducting traditional two-handed phacoemulsification through two relatively small incisions by using a phacoemulsification tip/sleeve with reduced diameter along with a second irrigation tip, with or without an attached manipulation tool.
    Type: Grant
    Filed: September 9, 2004
    Date of Patent: June 27, 2006
    Assignee: Alcon, Inc.
    Inventor: Khiun F. Tjia
  • Surgical apparatus
    Patent number: 7063680
    Abstract: A method of conducting traditional two-handed phacoemulsification through two relatively small incisions by using a phacoemulsification tip/sleeve along with a second irrigation tip, with or without an attached manipulation tool.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: June 20, 2006
    Assignee: Alcon, Inc.
    Inventors: Eric Lee, Grace C. Liao
  • Serotonergic 5HTreceptor compounds for treating ocular and CNS disorders
    Patent number: 7060704
    Abstract: Compounds with 5HT7 receptor affinity (some of which are novel) useful for lowering IOP, improving blood flow to the optic nerve head and the retina, providing neuroprotection, and treating retinal diseases are disclosed. The Compounds are also useful for treating sleep disorders, depression, and other psychiatric disorders, such as, schizophrenia, anxiety, obsessive compulsive disorder, circadian rhythm disorders, and centrally and peripherally mediated hypertension. Compositions and methods for their use are also disclosed.
    Type: Grant
    Filed: April 7, 2005
    Date of Patent: June 13, 2006
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Jesse A. May, Thomas R. Dean, Najam A. Sharif, Hwang-Hsing Chen
  • Carrageenan viscoelastics for ocular surgery
    Patent number: 7060297
    Abstract: Disclosed are carrageenan-based transitional viscoelastics that will induce little or no IOP spike when left in the eye at the close of surgery thereon. Drug delivery systems for delivering therapeutic agents during post-operative recovery stages are also disclosed.
    Type: Grant
    Filed: November 5, 2001
    Date of Patent: June 13, 2006
    Assignee: Alcon, Inc.
    Inventors: Mutlu Karakelle, Michael R. Brunstedt
  • 11,12-oxidoarachidonic acid derivatives and methods of their use in treating dry eye disorders
    Patent number: 7060728
    Abstract: 11,12-Oxidoarachidonic acid derivatives and methods of their use for treating dry eye are disclosed.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: June 13, 2006
    Assignee: Alcon, Inc.
    Inventors: David B. Belanger, Peter G. Klimko
  • High throughput assay for human Rho kinase activity
    Publication number: 20060115870
    Abstract: The present invention provides a high throughput assay for human Rho kinase activity in vitro, and methods and kits therefor. A high throughput method of assaying a test compound for human Rho kinase modulating activity is also provided.
    Type: Application
    Filed: March 25, 2005
    Publication date: June 1, 2006
    Applicant: Alcon, Inc.
    Inventors: Najam Sharif, Colene Drace, Gary Williams
  • Optimization of ablation correction of an optical system and associated methods
    Patent number: 7044944
    Abstract: A system and method for converting measured wavefront data into an ablation profile for correcting visual defects includes providing measured wavefront data on an aberrated eye by a method such as known in the art. The measured wavefront data are correlated with accumulated data on previously treated eyes. Next an adjustment is applied to the measured wavefront data based upon the correlating step. This adjustment is used to form adjusted wavefront data for input to a wavefront data correction algorithm to calculate an ablation profile therefrom. The wavefront data correction algorithm may be modeled as, for example, Zernike polynomials with adjusted coefficients.
    Type: Grant
    Filed: September 10, 2002
    Date of Patent: May 16, 2006
    Assignee: Alcon RefractiveHorizons, Inc.
    Inventors: John Alfred Campin, George H. Pettit
  • Surgical console
    Patent number: 7044568
    Abstract: A surgical console having a panel display mounted on a three-axis gimbel that permits articulation of the panel display via swivel, spin and tilt axes. The articulation mechanism uses two helix cable wraps with a single continuous cable that allows for large rotation of the panel display. The continuous cable simplifies construction and minimizes the electrical signal noise to the panel display.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: May 16, 2006
    Assignee: Alcon, Inc.
    Inventors: Argelio M. Olivera, Douglas T. Packard
  • Use of low molecular weight amino alcohols in ophthalmic compositions
    Patent number: 7045095
    Abstract: The use of low molecular weight amino alcohols in ophthalmic compositions is described. These compounds have been found to enhance the efficacy of anti-microbial preservatives.
    Type: Grant
    Filed: June 28, 2005
    Date of Patent: May 16, 2006
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Bahram Asgharian
  • Diagnostics and therapeutics for glaucoma
    Patent number: 7033755
    Abstract: Methods and compositions for diagnosing and treating glaucoma are disclosed.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: April 25, 2006
    Assignees: Alcon, Inc., University of Iowa Research Foundation
    Inventors: Abbot F. Clark, John Fingert, Loretta McNatt, Edwin M. Stone, Wan-Heng Wang
  • Accommodative intraocular lens
    Patent number: 7029497
    Abstract: A single optic accommodative lens. The lens includes a non-circular ring with radial dimensions that are different in at least two meridians. The radial dimension of vertical meridian of the lens approximates the natural diameter of the capsular bag. The optic of the lens is connected to the ring at the vertical meridian by a pair of haptics.
    Type: Grant
    Filed: May 21, 2003
    Date of Patent: April 18, 2006
    Assignee: Alcon, Inc.
    Inventors: Xiaoxiao Zhang, Yin Yang
  • Use of amidoamines to treat or prevent acanthamoeba and fungal infections
    Patent number: 7025958
    Abstract: The use of amidoamines to treat or prevent infections attributable to Acanthamoeba and fungi is described. The amidoamines are highly effective against both Acanthamoeba and fungi, and are less toxic to delicate tissues that may become infected with these types of microorganisms (e.g., the cornea).
    Type: Grant
    Filed: November 27, 2001
    Date of Patent: April 11, 2006
    Assignee: Alcon, Inc.
    Inventors: Ronald L. Schlitzer, Nissanke L. Dassanayake, Ruth Ann Rosenthal, Sally L. Buck
  • Methods of treating dry eye disorders
    Patent number: 7026296
    Abstract: Inhibitors of cytokine synthesis in nonimmune, resident ocular surface cells are useful for treating dry eye disorders and other disorders requiring the wetting of the eye.
    Type: Grant
    Filed: August 26, 2003
    Date of Patent: April 11, 2006
    Assignee: Alcon, Inc.
    Inventor: Daniel A. Gamache
  • Footswitch
    Patent number: 7019234
    Abstract: An improved footswitch is disclosed. The footswitch may have an adjustable length treadle to accommodate different size feet. The footswitch may also have a treadle having a slidable plate that facilitates the actuation of a side switch.
    Type: Grant
    Filed: September 7, 2004
    Date of Patent: March 28, 2006
    Assignee: Alcon, Inc.
    Inventors: Victor B. Mezhinsky, Mark A. Hopkins
  • Tapered infusion sleeve portal
    Patent number: 7014629
    Abstract: A tapered infusion sleeve that has an orifice whose exterior margin is either rounded off, beveled, tapered, curved inclined or otherwise forms an angle with an adjacent exterior of the sleeve that is other than ninety degrees and other than substantially ninety degrees. As a result, the exterior margin is less likely to become caught or ensnared when being passed through an incision opening with a surgical instrument.
    Type: Grant
    Filed: December 13, 2002
    Date of Patent: March 21, 2006
    Assignee: Alcon, Inc
    Inventor: Richard J. Mackool