Abstract: Various embodiments of systems and methods for cross media joint friend and item recommendations are disclosed herein.

Abstract: A multichip system includes a plurality of processor chips each having one or more cores and a plurality of antenna module for establishing interchip wireless communication. Each antenna module is disposed on a chip. At least one antenna module includes an antenna element array and a Butler matrix. The antenna element array includes n circular patch antenna elements for 360° end-fire scanning, where n is equal to 4 or a multiple thereof. The Butler matrix has n/4 submatrices. Each submatrix include two input 90° hybrids each having two outputs and two inputs for selectively receiving signals from a transceiver. The Butler matrix also includes two output 90° hybrids each having two outputs and two inputs. The two inputs of each output 90° hybrid are coupled to an output of different ones of the input 90° hybrids. Each output of the output 90° hybrids are coupled to a different antenna element.

Abstract: An optical apparatus is provided for manipulating light from x-ray sources (e.g., free electron lasers). In some embodiments, the optical apparatus includes a first capillary optic having a first longitudinal axis and a second capillary optic having a second longitudinal axis that is angled with respect to the first longitudinal axis. The second capillary optic is positioned to receive light directly from the first capillary optic.

Abstract: An adaptive force guidance system for laparoscopic surgery skills training includes self-adjusting fuzzy sliding mode controllers and switching mode controllers to provide proper force feedback. Using virtual fixtures, the system restrictS motions and/or guide a trainee to navigate a surgical instrument in a 3D space in a manner that mimics a human instructor who would teach trainees by holding their hands. The self-adjusting controllers incorporate human factors such as different force sensitivity and proficiency level.

Abstract: The present disclosure is directed to systems and methods of providing the next generation of quantum enabled cyber security systems. Such systems include a quantum network of satellites that will provide global coverage. The quantum satellite network includes quantum subnetworks comprised of LEO satellites. Some of these LEO satellite-based quantum subnetworks are connected to a subnetwork of MEO satellites. The MEO satellite subnetworks may then be interconnected to the global network of GEO satellites. The LEO/MEO satellites may also be used to interconnect terrestrial quantum networks. Each quantum communication subnetwork may be based on the cluster state concept.

Abstract: Disclosed are methods and systems that include obtaining at least one image of a dendritic structure, analyzing the at least one image to identify one or more features associated with the dendritic structure, and determining a numerical value associated with the dendritic structure based on the one or more features.

Abstract: Described herein are in situ synthesized arrays and methods of making the them, wherein array signal sensitivity and robustness is enhanced by carrying out conditioning steps and/or generating linkers during synthesis. An array comprises a surface with a collection of features, wherein the features comprise molecules or polymers attached to the surface. In certain embodiments of the invention, carrying out conditioning steps during array synthesis can yield arrays with improved signal. In other embodiments, linkers are synthesized on the array surface prior to synthesis of functional molecules, wherein increasing linker length can correspond to an improvement in the signal generated by the array.

Abstract: The disclosure relates to vaccination compositions, for example, against human papillomavirus, Zika virus, and flu virus. The disclosure also relates to vectors for producing the virus-like particles and immune complex platforms of the vaccination compositions.

Abstract: A physical unclonable functions (PUF) device including a first copper electrode, a second electrode, and a silicon oxide layer positioned directly between the first copper electrode and the second electrode; a method of producing a PUF device; an array comprising a PUF device; and a method of generating a secure key with a plurality of PUF devices.

Abstract: An optomechanical inertial reference mirror combines an optomechanical resonator with a reflector that serves as an inertial reference for an atom interferometer. The optomechanical resonator is optically monitored to obtain a first inertial measurement of the reflector that features high bandwidth and high dynamic range. The atom interferometer generates a second inertial measurement of the reflector that features high accuracy and stability. The second inertial measurement corrects for drift of the first inertial measurement, thereby resulting in a single inertial measurement of the reflector having high bandwidth, high dynamic range, excellent long-term stability, and high accuracy. The reflector may be bonded to the resonator, or formed directly onto a test mass of the resonator. With a volume of less than one cubic centimeter, the optomechanical inertial reference mirror is particularly advantageous for portable atomic-based sensors and systems.

Abstract: This invention is in the field of medicinal chemistry and relates to a new class of small-molecules having a pyrrolidinone-acetamide (or similar) structure (e.g., Formula I) which function as inhibitors of the SARS-CoV-2 papain-like protease (PLpro), which function as inhibitors of the SARS-CoV-2 related viral 3CL protease (MPpro), which function as therapeutics for the treatment of viral infection characterized with PLPpro and/or Mpro protease activity and/or expression (e.g., COVID-19), and which function as therapeutics for the treatment of other conditions characterized with PLPpro and/or Mpro protease activity and/or expression.

Abstract: A security framework for life-critical and safety-critical devices, specifically medical devices, using: a) runtime, adaptive methods that dynamically assess the risk of newly discovered vulnerabilities and threats, and b) automatic mitigation methods that reduce system risk by seamlessly reconfiguring the device to operate within different execution modes. This technology automatically isolates threats by disabling affected system components. A multi-modal software design uses adaptive software in which operational modes have monotonically decreasing cumulative risk. Formal risk models are used to model the individual risk of accessing or controlling system components and to automatically calculate the cumulative risk of software modes. The automated detection of potential threats by the system or reporting of known vulnerabilities will dynamically change the system risk.

Abstract: Methodology of unwrapping of phase from an optical image in the presence of both noise and unreliable phase fringes configured to tackle both problems simultaneously and, in the most efficient of multiple related implementations, including at least three prongs: i) SD-ROM based denoising procedure, ii) reliable estimation of the gradient of both the wrapped and unwrapped phase with the use of the forward and inverse Laplacian operators; and iii) fringe quality improvement with the use of Fuzzy Logic based Edge Detection. Transformation of optical images with the use of such methodology to provide an image representing visually-perceivable representation of the object's shape. Computer program product configured to implement the same.

Abstract: Methods and systems are provided for serial femtosecond crystallography for reducing the vast amount of waste of injected crystals practiced with traditional continuous flow injections. A micrometer-scale 3-D printed water-in-oil droplet generator device includes an oil phase inlet channel, an aqueous phase inlet channel, a droplet flow outlet channel, and two embedded non-contact electrodes. The inlet and outlet channels are connected internally at a junction. The electrodes comprise gallium metal injected within the 3-D printed device. Voltage across the electrodes generates water-in-oil droplets, determines a rate for a series of droplets, or triggers a phase shift in the droplets. An external trigger generates the droplets based on the frequency of an XFEL utilized in droplet detection, thereby synchronizing a series of droplets with x-ray pulses for efficient crystal detection. The generated droplets can be coupled to an SFX with XFEL experiment compatible with common liquid injector such as a GDVN.

Abstract: An auscultation system comprises an auscultation device comprising a wearable apparatus positionable proximate to a lung, a plurality of audio sensors embedded in the wearable apparatus configured to record lung sounds, wherein the plurality of audio sensors are positioned at locations of the wearable apparatus corresponding to lung auscultation points, and a computing system communicatively connected to the auscultation device, comprising a processor and a non-transitory computer-readable medium with instructions stored thereon, which when executed by a processor, perform steps comprising, establishing a background noise spectrum, recording a lung sound spectrum via the auscultation device for a period of time, calculating a background subtracted lung sound spectrum by subtracting the background noise spectrum from the measured lung sound spectrum, analyzing the background subtracted lung sound spectrum to produce an auscultation result, and providing the auscultation result to a practitioner to assist in pr

Abstract: Various embodiments of a variable geometry quadrotor with a compliant frame are disclosed, which adapts to tight spaces and obstacles by way of passive rotation of its arms.

Abstract: Provided herein are methods of modulating temperature in detection fields and producing analyte imaging data. In some embodiments, the methods include introducing an incident light toward a second surface of a substrate to induce a plasmonic wave proximal to a first surface of the substrate such that a temperature in a selected heating space within the detection field is substantially uniformly changed to a selected temperature. Additional methods as well as related systems and computer readable media are also provided.

Abstract: A Processing-in-Memory (PIM) design is disclosed that converts any memory sub-array based on non-volatile resistive bit-cells into a potential processing unit. The memory includes the data matrix stored in terms of resistive states of memory cells. Through modifying peripheral circuits, the address decoder receives three addresses and activates three memory rows with resistive bit-cells (i.e., data operands). In this way, three bit-cells are activated in each memory bit-line and sensed simultaneously, leading to different parallel resistive levels at the sense amplifier side. By selecting different reference resistance levels and a modified sense amplifier, a full-set of single-cycle 1-/2-3-input reconfigurable complete Boolean logic and full-adder outputs could be intrinsically readout based on input operand data in the memory array.

Abstract: Solvent free epoxy system that includes: a hardener compound H comprising: a molecular structure (Y1—R1—Y2), wherein R1 is an ionic moiety Y1 is a nucleophilic group and Y2 nucleophilic group; and an ionic moiety A acting as a counter ion to R1; and an epoxy compound E comprising: a molecular structure (Z1—R2—Z2), wherein R2 is an ionic moiety, Z1 comprises an epoxide group, and Z2 comprises an epoxide group; and an ionic moiety B acting as a counter ion to R2. In embodiments, the epoxy compound E and/or the hardener H is comprised in a solvent-less ionic liquid. The systems can further include accelerators, crosslinkers, plasticizers, inhibitors, ionic hydrophobic and/or super-hydrophobic compounds, ionic hydrophilic compounds, ionic transitional hydrophobic/hydrophilic compounds, biological active compounds, and/or plasticizer compounds. Polymers made from the disclosed epoxy systems and their methods of used.

Abstract: Described here are systems and methods for generating and implementing a hybrid machine learning and mechanistic model to produce biological feature maps, or other measurements of biological features, based on an input of multiparametric magnetic resonance or other images. The hybrid model can include a combination of a machine learning model and a mechanistic model that takes as an input multiparametric MRI, or other imaging, data to generate biological feature maps (e.g., tumor cell density maps), or other measures or predictions of biological features (e.g., tumor cell density). The hybrid models have capabilities of learning individual-specific relationships between imaging features and biological features.