Abstract: The present disclosure provides a novel primer reagent for detecting a plurality of variants of the ALK fusion gene.

Abstract: Provided are a measuring apparatus and method for obtaining a measurement value from a response to a signal applied to a sample, wherein the measuring apparatus includes a first measuring unit that measures a first electric response to a first signal that is input to a first pair of electrodes that can come into contact with a sample, a second measuring unit that measures a second electric response to a second signal that is input to a second pair of electrodes that can come into contact with the sample, the second signal changing its value from a first level to a second level and thereafter maintaining the second level for a certain period of time, as a peak value of a response signal with respect to the change in the second signal, and a control unit that corrects a value indicating the amount of a measuring target component of the sample, the value being obtained from the first electric response, based on the peak value of the response signal.

Abstract: The amount of consumption of a washing solution for a nozzle and the required time for washing are reduced. A nozzle washing apparatus usable for collection of a specimen comprises a washing tank which accommodates a nozzle, a first discharge port which discharges a washing solution supplied into the washing tank from an upper portion of the washing tank, a second discharge port which discharges the washing solution supplied into the washing tank from a position lower than the first discharge port of the washing tank, a detector which detects a range of contact of an outer wall of the nozzle with the specimen, and a controller which discharges the washing solution supplied into the washing tank from one of the first discharge port and the second discharge port on the basis of a detection result obtained by the detector.

Abstract: The present disclosure provides component analysis methods including a measurement process and an analysis process.

Abstract: [Problem to Be Solved] The present invention provides an optical element including a coating film in which the occurrence of cracks is prevented. [Solution] Provided is an optical element including: an optical crystal; and an antireflection film coating the surface of the optical crystal; in which optical element the antireflection film contains an organic compound.

Abstract: An enzyme electrode includes an electrode, and a detection layer which contacts the electrode and contains a crosslinking agent, an electrically conductive macromolecule and an enzyme transferring and receiving electrons to and from the electrode and does not contain an electron transfer subunit.

Abstract: The disclosure discloses an enzyme electrode comprising; an electrode comprising a current collector; a monolayer-forming molecule bound to the surface of the current collector; and a glucose dehydrogenase comprising a cytochrome C subunit bound to the monolayer-forming molecule; wherein electrons are transferred between the glucose dehydrogenase and the current collector by oxidation-reduction reaction of the glucose dehydrogenase.

Abstract: Provided is a radioactive labeled compound capable of detecting a secondary mutation of an epidermal growth factor receptor, where the compound is represented by Formula (1) or a pharmaceutically acceptable salt thereof, where R1, R2, and Y are as defined.

Abstract: The present disclosure provides an analysis chip device used in capillary electrophoresis.

Abstract: The present disclosure provides an analysis chip device used in capillary electrophoresis.

Abstract: An analytical tool for use in analysis of a sample is provided. The analytical tool includes a first unit and a second unit. The first unit has an analysis portion where analysis is performed. The second unit, configured to be coupled with the first unit, has a liquid reservoir for confining a particular liquid used for the analysis of the sample. When the first unit and the second unit are coupled, a fluid passage for conducting the particular liquid from the liquid reservoir into the first unit is formed by only a part of the first unit, or only a part of the second unit, or a combination of respective parts of the first unit and the second unit.

Abstract: The disclosure provides plasma spectroscopy analysis methods using a preparatory process of adding a control metal species that is different from an analyte metal species to a sample so as to have a known concentration; a concentration process of introducing the sample to a measurement container, and applying an electric current across a pair of electrodes disposed in the measurement container to concentrate the analyte metal species and the control metal species in the sample in a vicinity of at least one of the electrodes; a detection process; a correction process; and a quantification process.

Abstract: A sample analysis method capable of improving separation accuracy of at least one of hemoglobin A2 and hemoglobin S and downsizing an analysis device is provided. The method includes separating hemoglobin in a sample in an alkaline solution containing a cationic polymer by capillary electrophoresis.

Abstract: The disclosure provides plasma spectroscopy analysis methods using a preparatory process of diluting a urine sample assumed to contain mercury or lead as an analyte metal species, and then adding a known concentration of thallium as a control metal species to the diluted urine sample; a concentration process of introducing the urine sample containing the control metal species to a measurement container, and applying an electric current across a pair of electrodes disposed in the measurement container to concentrate the analyte metal species and the control metal species present in the urine sample in a vicinity of at least one of the electrodes; a detection process; a correction process; and a quantification process.

Abstract: An analysis method using a microchip which is provided with a capillary flow path, and a sample reservoir connected to the capillary flow path, in which the capillary flow path is filled with a first liquid for electrophoresis, and a second liquid containing a sample is stored in the sample reservoir, and including a pressurization process in which the first liquid is pressurized into the capillary flow path from a side of the capillary flow path that is opposite from the side connected to the sample reservoir, and a separation process in which a voltage is applied between the sample reservoir storing the second liquid and the capillary flow path filled with the first liquid, such that components in the sample contained in the second liquid move in the capillary flow path and the components are separated in the capillary flow path.

Abstract: A liquid chromatography measurement method includes: switching between a first measurement mode using a liquid chromatography method in which hemoglobin A1c and a hemoglobin variant are measured in a measurement sample by sequentially delivering a first component-separating eluent, a second component-separating eluent and a wash eluent to an analytical column, and a second measurement mode using the liquid chromatography method in which the hemoglobin A1c is measured by sequentially delivering the first component-separating eluent and the wash eluent to the analytical column; delivering the wash eluent in the first measurement mode prior to an influence from the second component-separating eluent disappearing such that a first retention time of the hemoglobin A1c in the first measurement mode and a second retention time of the hemoglobin A1c in the second measurement mode are substantially the same as each other; and delivering the first component-separating eluent after the wash eluent.

Abstract: The present invention provides a novel target analysis chip and analysis method for directly detecting a target such as a microRNA without performing PCR.

Abstract: A measurement apparatus for measuring a target substance in a sample adhered to a sensor includes a plurality of conductive portions that includes a first conductive portion group extending in an insertion direction of the sensor, and a second conductive portion group extending in a direction intersecting with the insertion direction. In the inserted state, the first conductive portion group is configured to contact with electrode pads corresponding to the first conductive portion group, and the second conductive portion group is configured to contact with electrode pads other than the electrode pads corresponding to the first conductive portion group.

Abstract: A method for treating collected blood to be used in a test for rare cells in blood that includes mixing the collected blood with an agent that increases the intracellular concentration of cAMP or an analogous compound thereof, where the method for performing the test for rare cells in blood, includes using blood treated by the method described herein as the blood sample to be subjected to the test.

Abstract: By using a mutant glucose oxidase comprising an amino acid sequence in which a residue corresponding to isoleucine at position 489 or arginine at position 335 in the amino acid sequence of SEQ ID NO:1 is substituted with an amino acid residue having a reactive functional group in a side chain, and binding an electron acceptor to the mutant glucose oxidase through the amino acid residue having a reactive functional group, an electron acceptor-modified glucose oxidase is obtained.