Abstract: A method for quantifying a target substance, comprising: bringing a sample containing the target substance into contact with a biosensor which comprises an enzyme electrode containing an oxidoreductase and a counter electrode; measuring a change in the potential difference between the enzyme electrode and the counter electrode due to oxidation reaction of the target substance catalyzed by the oxidoreductase; and calculating the concentration of the target substance based on the change in the potential difference; wherein a potential is applied between the enzyme electrode and the counter electrode before the measurement of the change in the potential difference.

Abstract: An electrochemical sensor includes a base member, a conductor disposed on the base member, an insulating layer covering the conductor with a portion of the conductor exposed, a silver/silver chloride electrode formed on at least the exposed portion of the conductor, and a water-permeable organic layer covering the silver/silver chloride electrode.

Abstract: A plasma spectroscopy analysis method includes a preliminary addition process in which a bonding agent that is an agent other than DMSA is added to the specimen collected from a living body to which meso-2,3-dimercaptosuccinic acid (DMSA) is administered, a concentration process in which the analyte heavy metal ions in the specimen at a vicinity of one of a pair of electrodes by applying a voltage to the pair of electrodes, and a detection process in which plasma is generated by applying a voltage to the pair of electrodes, and luminescence of the analyte metal ions caused by the plasma is detected.

Abstract: Provided is a measuring method using a biosensor, the method including: introducing a sample containing a substance to be measured into an electrochemical measurement cell, wherein the electrochemical measurement cell comprises: an insulating base plate; and an electrode system applying a first voltage to the electrode system; applying a second voltage to the electrode system; obtaining a first signal; obtaining a second signal; and correcting the second signal by the first signal, to determine the concentration of the substance to be measured in the sample.

Abstract: A plurality of images of a sample are simultaneously captured at different focal lengths by a plurality of cameras. An analysis apparatus includes: a branch section configured to cause light passing through the sample containing a material component to branch off into a plurality of optical paths; a plurality of imaging devices for simultaneously capturing images of the sample in a flow path at different focal points by using the light caused to branch off into the plurality of optical paths; and a controller configured to process the captured images.

Abstract: This disclosure provides an ion-selective electrode enhanced in simultaneous repeatability, a test specimen using the ion-selective electrode, and an analyzer using the test specimen. The ion-selective electrode is provided with: a pair of internal electrodes; and an ion-selective membrane which is provided at respective positions corresponding to the internal electrodes and which includes a binder resin, an ionophore, and a dielectric material having a dielectric constant of 10 or more.

Abstract: The present invention provides a mutant-type glucose dehydrogenase having glucose dehydrogenase activity and having decreased reactivity with xylose, wherein said mutant-type glucose dehydrogenase comprises a mutant-type ?-subunit comprising an amino acid sequence of 520 to 550 amino acids comprising an amino acid sequence of 520 to 550 amino acids comprising SEQ ID NO: 21, SEQ ID NO: 22, SEQ ID NO: 23, SEQ ID NO: 24 and SEQ ID NO: 25 in this order from N-terminus to C-terminus, except that one or more amino acid residue(s) selected from the group consisting of the glycine at position 10 in SEQ ID NO: 23, the histidine at position 4 in SEQ ID NO: 24, and the asparagine at position 4 in SEQ ID NO: 25 is/are substituted with another/other amino acid(s).

Abstract: Provided is a measurement system for performing qualitative measurement and quantitative measurement of a measurement item of a biological sample, the measurement system including a quantitative sample adjustment criterion storage section that stores a quantitative sample adjustment criterion corresponding to a qualitative measurement result in the qualitative measurement, a determination section that determines a proper quantitative sample adjustment condition by referring to the quantitative sample adjustment criterion to determine necessity to change the quantitative sample adjustment condition based on the qualitative measurement result, and an adjustment section that adjusts the biological sample based on the quantitative sample adjustment condition determined by the determination section.

Abstract: A method of performing an intravenous drip injection includes a first step, a second step, a third step and a fourth step. A first step includes starting dosing an infusion solution containing a predetermined component by the intravenous drip injection to a dosing recipient. A second step includes extracting a body fluid from the dosing recipient being dosed with the infusion solution. A third step includes measuring a concentration of the predetermined component in the extracted body fluid. A fourth step includes varying the concentration of the predetermined component in the infusion solution, corresponding to the concentration of the predetermined component in the body fluid.

Abstract: The present invention provides an immunoassay analyzer capable of discriminating between normal coloring due to a specific immunoreaction and abnormal coloring due to a cause other than the specific immunoreaction in a measurement region of a sample analysis tool. An immunoassay analyzer 1 of the present invention includes an optical detection unit 4 and a determination unit 5. The optical detection unit 4 includes an optical signal measurement unit for measuring an optical signal at each of two or more different wavelengths including a main wavelength for detecting color change due to the specific immunoreaction and a sub-wavelength(s) other than the main wavelength. The determination unit 5 includes a discrimination unit for comparing the respective optical signals at the two or more different wavelengths and discriminating between the color change due to the specific immunoreaction and color change due to a cause other than the specific immunoreaction based on a comparison criterion determined previously.

Abstract: Provided is a method for measuring the concentration of a substance in a blood sample, the method comprising the steps of: supplying the blood sample to a biosensor comprising a hematocrit electrode for measuring a hematocrit value on the surface of which electrode an electrically conductive polymer is coated by physical adsorption in the absence of a crosslinking agent; and calculating the concentration of the substance from the measured value of a first current resulting from application of a first voltage; and correcting the concentration of the substance with the value of a second current resulting from application of a second voltage or the hematocrit value calculated from the value of the second current.

Abstract: The disclosure provides for a method for determining the stage of a periodontal disease by using as an index the amount of occult blood, and the number of white blood cells or a total protein concentration in the examination object obtained from the oral cavity.

Abstract: A plasma spectroscopic analysis method includes a concentration process of concentrating a target in a sample, in the vicinity of one of a pair of electrodes in the presence of the sample; a plasma generation process of generating plasma in the sample by applying a voltage to the pair of electrodes; and a detection process of detecting emission of the target generated by the plasma, wherein the plasma generation process is performed in the presence of a defoaming agent.

Abstract: There is provided a sensor testing method including: applying at least one of a first voltage that obtains a response caused by a substance and a second voltage that either obtains no response or substantially no response caused by the substance across a first electrode and a second electrode of a sensor; measuring current flowing between the first electrode and the second electrode; and determining whether or not there is a defect present in the sensor based on a quantity related to an amount of change per specific period of time of a current measured when the first voltage and/or the second voltage have been applied.

Abstract: Provided is a method for measuring a glycoprotein using an enzymatic method, and the method includes simplified steps.

Abstract: Provided is a reagent that is suitable for measurement of a glycoprotein and contains a compound capable of stabilizing a leuco dye.

Abstract: Provided is a blood measuring apparatus including: a spectroscope; an optical system configured to irradiate a living body with excitation light from a light source, and to guide, to the spectroscope, Raman scattered light from the living body; a control unit configured to adjust an irradiation position at which the living body is irradiated with the excitation light by the optical system; and a detector configured to detect a spectrum of the Raman scattered light using light of each wavelength dispersed by the spectroscope. A plurality of the spectra detected by the detector are integrated, and numerical value information regarding a substance included in blood of the living body is measured based on an integration result, and the control unit adjusts the irradiation position such that the plurality of spectra are detected at changed positions.

Abstract: An analysis device that includes a placement section, a pressing member, and a measurement member, has an analysis kit including a chip provided with a capillary through which a sample flows and a cartridge superimposed on the chip, and in which a liquid reservoir placed therein to enable a component present in sample can be measured in a state in which the chip and the cartridge have been fitted together. The analysis kit is placed on the placement section. The pressing member presses the analysis kit in a direction in which the cartridge is superimposed on the chip to sandwich the analysis kit between the pressing member and the placement section, and to fit the chip and the cartridge together. The measurement member that measures the component present in the sample in the analysis kit in which the chip and the cartridge have been fitted together.