Abstract: Disclosed is an electrochemical sensor for the determination of analytes in body fluids, e.g. glucose in blood. The sensor involves a non-conductive base which provides a flow path for the body fluid with the base having a working and counter electrode on its surface which are in electrical communication with a detector of current. The base and a cover therefore provide a capillary space containing the electrodes into which the body fluid is drawn by capillary action. The counter electrode has a sub-element which contains an electroactive material and is configured in the system (sensor and meter) to provide an error signal when insufficient body fluid is drawn into the capillary.

Abstract: Method of dispensing moist, sticky or statically charged bulk material into a fluid pervious container having an opening for receiving said bulk material, which comprises conveying a bulk material, as a suspension or dispersion in a fluid, from a reservoir, and introducing said suspension or dispersion into the fluid-pervious container through said opening in the container to pass the fluid component of the suspension or dispersion through and out of the fluid-pervious container while the retaining the bulk material within the container, and recirculating the fluid to the reservoir.

Abstract: The present invention provides a novel process for the preparation of isoolefin copolymers in the presence of zirconium halides and/or hafnium halides and organic acid halides, in particular for the preparation of butyl rubbers, as well as isoolefin copolymers constructed of isobutene, isoprene and optionally further monomers.

Abstract: An aqueous polyurethane resin dispersions containing i) a polyol component with a molecular weight above 300 daltons, containing a polyether diol initiated on an aromatic diol, ii) a polyol component with a molecular weight of 62 to 299 daltons, iii) a monofunctional isocyanate-reactive compound with an ethylene oxide content of at least 50 wt. % and a molecular weight of at least 400 daltons, iv) a polyisocyanate v) an aliphatic polyamine with a molecular weight of 60 to 300 daltons or hydrazine, and vi) a hydrophilic aliphatic diamine, a process for making the dispersion and substrates primed with the dispersion.

Abstract: The present invention relates to biphenyl and biphenyl-analogous compounds, their preparation and use as pharmaceutical compositions, as integrin antagonists and in particular for the production of pharmaceutical compositions for the treatment and prophylaxis of cancer, arteriosclerosis, restenosis, osteolytic disorders such as osteoporosis and ophthalmic diseases. The compounds according to the invention have the formula (1) wherein R1, R2, U, V, A, B, W, R3, C and R4 have the meaning as defined in the claims.

Abstract: N-(3-benzofuranyl)urea-derivatives are prepared by reacting of 3-amino-substituted benzofuranes with appropriate substituted isocyanates or isothiocyanates. The N(3-benzofuranyl)urea-derivatives can be used as active ingredients in medicaments particularly for the treatment of acute and chronic inflammatory processes.

Abstract: There is described a method for the storing of elastan filaments with a titre of at least 2,500 dtex in drums with a filament line length of at least 10 km with the use of a displacing device, in which the filaments are stored meandering in layers, and in which the filaments are inlaid into the drum at a speed of at least eight per cent above the production speed of the filaments.

Abstract: The invention relates to novel sulfonylamino(thio)carbonyl compounds of the formula (I), in which n represents the numbers 0, 1 or 2, A represents a single bond, or oxygen or sulfur, or the grouping N—R, in which R represents hydrogen, alkyl, alkenyl, alkinyl or cycloalkyl, Q represents oxygen or sulfur, R1 represents hydrogen or formyl, or represents respectively optionally substituted alkyl, alkoxy, alkylamino, alkoxyamino, dialkylamino, N-alkoxy-N-alkyl-amino, alkylcarbonyl, alkoxycarbonyl, alkylsulfonyl, alkenyl, alkinyl, cycloalkyl, cycloalkylcarbonyl or cycloalkylsulfonyl, R2 represents cyano or halogen, or represents respectively optionally substituted alkyl, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl, dialkylaminosulfonyl, alkenyl, alkinyl, alkenyloxy or alkinyloxy, and R3 represents respectively optionally substituted heterocyclyl having 5 ring members of which at least one is oxygen, sulfur or nitrogen and from one to three further ring members can be nitrogen, an

Abstract: The present invention relates to a method for preparing pseudo islets. In addition, the invention is also directed to methods of treating diabetes and diabetes-related disorders by administering compounds identified by the methods described herein.

Abstract: One embodiment of the present invention improves the visual use of urine test strips and reagent pads by providing a single color from a reference color spectrum directly on the colorimetric strip and adjacent to the reagent area to allow easy comparison. After application of a fluid to be tested to a reagent area on the colorimetric strip, a technician is able to easily compare the color in the reagent area to the reference color area(s) to determine the presence or absence of, for example, glucose, in the fluid. Placing at least one reference color immediately next to the reagent area markedly improves technician's accuracy in comparing and analyzing the reagent area against the reference color(s). The present invention allows a technician to easily and quickly compare a reagent area color to more than one reference area to determine the actual numerical value of, for example, the pH in the tested fluid.

Abstract: The present invention discloses a method for the measurement of hydride using a chemiluminescent compound. The preferred chemiluminescent molecule is an acridinium compound. The source of hydride for the reduction of acridinium compound may be of chemical or biochemical origin, or the result of enzymatic catalysis. The chemical source of hydride, for example, might be metal hydrides, such as NaBH4. A biochemical source of hydride might be that derived from NADH, or NADPH, while an enzymatic source would be the class of oxidoreductases termed dehydrogenases which convert NADH or NADPH from NAD or NADP. There are numerous potential applications for acridinium compounds as chemiluminescent indicators of hydride. Any applied tests or diagnostic assays, in which hydride is either present at the onset of or generated through the course of a reaction, would benefit from the present invention.

Abstract: The invention relates to a process for preparing triethyl phosphate by reacting phosphorus oxychloride with a greater than stoichiometric quantity of ethanol under reduced pressure at temperatures of from 0 to 50° C. in a reaction vessel, wherein a) the volatile components resulting from the reaction are predominantly condensed by means of a reflux condenser and the remaining volatile components are passed into a scrubber filled with water, b) after the end of the reaction, the reaction mixture is separated distillatively in an outgassing column into a top product and a bottom product which predominantly comprises triethyl phosphate, c) the top product of the outgassing column is combined with the contents of the scrubber and d) the contents of the scrubber are separated distillatively in an azeotropic distillation to obtain water and ethanol as top product and the ethanol, preferably after dewatering, is preferably returned to the reaction.

Abstract: A hydrogenated nitrile rubber having lower molecular weights and narrower molecular weight distributions than those known in the art can be prepared by the olefin metathesis of nitrile butadiene rubber, followed by hydrogenation of the resulting metathesized NBR.

Abstract: The present invention relates to a process for the epoxidation of hydrocarbons. This process comprises reacting at least one hydrocarbon with oxygen or air or nitrous oxide or other gaseous oxidants, in the presence of a mixture comprising at least two elements selected from the group consisting of Sc, Y, Ti, Zr, Hf, V, Nb, Ta, Cr, Mo, W, Re, Fe, Co, Ni, Sn, Pb, Sb, Bi and Se, on a support with a BET surface area of less than 200 m2/g. The present invention also relates to catalysts suitable for the epoxidation of hydrocarbons, wherein the catalyst comprises a mixture comprising at least two metals selected from the group consisting of Sc, Y, Ti, Zr, Hf, V, Nb, Ta, Cr, Mo, W, Re, Fe, Co, Ni, Sn, Pb, Sb, Bi and Se, on a support with a BET surface area of less than 200 m2/g.

Abstract: Disclosed herein is a process for preparing a reaction product containing methylene diphenylamine, comprising reacting aniline and formaldehyde in the presence of an acid catalyst wherein the acid level of the resulting reaction mixture is reduced during digestion of the reaction mixture.

Abstract: The invention relates to a novel process for preparing fluorosulfonic acid having low contents of low-boiling compounds in which hydrogen fluoride and sulfur trioxide are combined in stoichiometric amounts in a reaction vessel or by means of a reaction nozzle, the hot, gaseous fluorosulfonic acid that is formed is fed directly into a distillation column, and the fluorosulfonic acid is taken off at the bottom of the column or in the stripping section of the distillation column.

Abstract: Air-assisted, low pressure spray equipment having an improved spray nozzle including a caulking gun having a carriage adapted to receive cartridges having a nozzle, rams mounted on the caulking gun for engaging each cartridge to dispense a liquid from the nozzle, a trigger mechanism for advancing the rams into operative engagement with each cartridge; a static mixer having an inlet port for receiving a liquid component from the nozzle of each cartridge and having an optional spray tip for introducing the mixed liquid components into an atomizing zone; a static mixer shroud encasing the static mixer and an optional spray section having inlet ports for receiving pressurized air and outlet ports for introducing air into the atomizing zone. The spray tip passes through an orifice in the spray section such that the mixed liquid components are introduced into the atomizing zone. The equipment is useful for spraying a two-component composition.

Abstract: The present invention relates to a process for producing sol-gel condensates by A1) reacting an aqueous silica sol with a silicon alkoxide and subsequently A2) converting the condensate obtained from A1) with a polyfunctional organosilane.

Abstract: Composites comprising a polyurethane core and an outer facing layer are described in the present invention. Suitable polyurethane cores are hydrophilic polyester-polyurethane foamed materials which comprise the reaction product of: (a) at least one polyisocyanate, with (b) at least one polyester polyol containing at least two hydroxyl groups and having an average molecular weight within the range from more than 700 to 10,000, and (c) at least one ethoxylated polyether polyol, containing at least two hydroxyl groups, having a molecular weight of at more than 700, a functionality of from 2 to 6, and having a degree of ethoxylation greater than 30% by weight, and (d) optionally, at least one compound containing at least two active hydrogen atoms and having an average molecular weight within the range from 32 to 700, and (e) catalysts, water and/or foaming agents, and (f) optionally, adjuvant substances and additives.

Abstract: Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.