Patents Assigned to Bayer
  • Process for preparing crosslinked ion exchangers based on unsaturated aliphatic nitriles
    Patent number: 6696503
    Abstract: The present invention relates to a process for preparing crosslinked ion exchangers with a homogeneous network structure based on unsaturated aliphatic nitriles in the presence of film-forming protective colloids.
    Type: Grant
    Filed: December 14, 2000
    Date of Patent: February 24, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Michael Happ, Ralf-Jürgen Born, Reinhold Klipper, Ulrich Schnegg, Hans-Karl Soest, Wolfgang Zarges
  • Process for preparing a polymer from 3,4-epoxy-1-butene
    Patent number: 6696531
    Abstract: The invention relates to a process for preparing a polymer by polymerizing a component containing 3,4-epoxy-1-butene in the presence of a double metal cyanide (DMC) catalyst and a hydroxy-functional starter and it also relates to the obtained polymers.
    Type: Grant
    Filed: February 18, 2003
    Date of Patent: February 24, 2004
    Assignee: Bayer Polymers LLC
    Inventors: Helmut Greiving, Peter J. Miller
  • Hydroxyl group-containing diene rubber
    Patent number: 6696523
    Abstract: The present invention relates to rubber mixtures containing diene rubber with a concentration of primary hydroxyl groups of 0.1 to 2 wt. % and a glass transition temperature of −120° to −50° C. and their mixtures with fillers, optionally further rubbers and rubber auxiliary substances and vulcanisates prepared therefrom. Rubber mixtures according to the invention are suitable for producing highly reinforced, abrasion-resistant moulded items, in particular for producing tires treads which have a particularly high resistance to wet skidding.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: February 24, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Scholl, Jürgen Trimbach
  • Double-metal cyanide catalysts which can be used to prepare polyols and the processes related thereto
    Patent number: 6696383
    Abstract: The present invention is directed to double metal cyanide catalysts (“DMC”) which can be used to prepare polyols. DMC catalysts of the present invention are prepared by combining i) at least one metal salt; ii) at least one metal cyanide salt; iii) at least one organic complexing ligand; iv) at least one alkaline metal salt; and, optionally, v) at least one functionalized polymer. The present invention is also directed to a process for preparing a polyol in the presence of a DMC catalyst prepared according to the process of the present invention. Surprisingly, DMC catalysts of the present invention, which are preferably prepared with at least one alkaline metal halide, have acceptable activity and can be used to catalyze oxyalkylation reactions. Additionally, DMC catalysts produced by the process of the present invention can be used to prepare polyols which have reduced levels of high weight tail.
    Type: Grant
    Filed: September 20, 2002
    Date of Patent: February 24, 2004
    Assignees: Bayer Polymers LLC, Bayer Antwerpen, NV.
    Inventors: Bi Le-Khac, Wei Wang
  • Liquid formulation
    Patent number: 6695975
    Abstract: The invention provides a suspo-emulsion formulation comprising defined first and second compatible components, the first component acting primarily as an oil emulsifier and secondarily as a particle dispersant, and the second component acting primarily as a particle dispersant and secondarily as an oil emulsifier. The invention enables the preparation of stable suspo-emulsions containing a variety of active ingredients and components and containing large quantities of oily components.
    Type: Grant
    Filed: March 12, 2001
    Date of Patent: February 24, 2004
    Assignee: Bayer Cropscience GmbH
    Inventors: Graham Kneebone, Smita Patel
  • Method and device for detecting Biologically Active Substances
    Publication number: 20040033587
    Abstract: The invention relates to a method for detecting biologically active substances, comprising the steps
    Type: Application
    Filed: April 25, 2003
    Publication date: February 19, 2004
    Applicant: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kreiss, Guenther Eberz, Hans-Georg Rast, Claus Weisemann
  • Methods and means to modulate programmed cell death in eukaryotic cells
    Patent number: 6693185
    Abstract: The invention provides for the use of isolated polynucleotides encoding maize poly (ADP-ribose) polymerase (PARP) proteins to produce eukaryotic cells and organisms, particularly plant cells and plants, with modified programmed cell death. Eukaryotic cells and organisms particularly plant cells and plants, are provided wherein either in at least part of the cells, preferably selected cells, the programmed cell death (PCD) is provoked, or wherein, on the contrary, PCD of the cells or of at least part of the cells in an organism is inhibited, by modulation of the level or activity or PARP proteins in those cells.
    Type: Grant
    Filed: July 17, 1998
    Date of Patent: February 17, 2004
    Assignee: Bayer Bioscience N.V.
    Inventors: Elena Babiychuk, Sergei Kushnir, Marc De Block
  • Pyridine-substituted pyrazolopyridine derivatives
    Patent number: 6693102
    Abstract: The present invention relates to new pyrazolopyridine derivatives of the formula (I) in which R1 represents 4-pyridinyl or 3-pyridinyl; R2 represents H, NH2 or halogen; and salts, isomers and hydrates thereof as stimulators of soluble guanylate cyclase and for use as agents for the treatment of cardiovascular disorders, hypertension, of thromboembolic disorders and ischaemia, sexual dysfunction or inflammation, and for the treatment of disorders of the central nervous system.
    Type: Grant
    Filed: November 1, 2001
    Date of Patent: February 17, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Johannes-Peter Stasch, Achim Feurer, Stefan Weigand, Elke Stahl, Dietmar Flubacher, Cristina Alonso-Alija, Frank Wunder, Dieter Lang, Klaus Dembowsky, Alexander Straub, Elisabeth Perzborn
  • Arylphenyl-substituted cyclic ketoenols
    Patent number: 6693092
    Abstract: The present invention relates to novel arylphenyl-substituted cyclic ketoenols of the formula (I) in which X represents halogen, alkyl, alkoxy, alkenyloxy, alkylthio, alkylsulphinyl, alkylsulphonyl, halogenoalkyl, halogenoalkoxy, halogenoalkenyloxy, nitro, cyano or in each case optionally substituted phenyl, phenoxy, phenylthio, phenylalkoxy or phenylalkylthio, Y represents in each case optionally substituted cycloalkyl, aryl or hetaryl, W and Y independently of one another each represent hydrogen, halogen, alkyl, alkoxy, alkenyloxy, halogenoalkyl, halogenoalkoxy, halogenoalkenyloxy, nitro or cyano, CKE represents one of the groups  in which A, B, D, G and Q1 to Q6 are each as defined in the description, to a plurality of processes for their preparation and to their use as pesticides and herbicides.
    Type: Grant
    Filed: May 9, 2002
    Date of Patent: February 17, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Folker Lieb, Reiner Fischer, Alan Graff, Udo Schneider, Thomas Bretshneider, Christoph Erdelen, Wolfram Andersch, Mark Wilhelm Drewes, Markus Dollinger, Ingo Wetcholowsky, Randy Allen Myers
  • Process for the utilization of vanadium from chromium ore as vanadium (V) oxide
    Publication number: 20040026330
    Abstract: Process wherein the vanadium present in the chromium ore chromite is recovered as vanadium pentoxide during the course of the fusion of the chromium ore with alkali and its work-up to produce sodium chromate solution and sodium dichromate.
    Type: Application
    Filed: April 1, 2003
    Publication date: February 12, 2004
    Applicant: Bayer Aktiengesellschaft
    Inventors: Rainer Weber, Hans-Dieter Block, Michael Batz, Jost Halstenberg, Michael Lumm, Roland-Luiz Roth, Dawie Van Der Merre
  • Fluid collecting and monitoring device
    Publication number: 20040028558
    Abstract: A device that is intended for the sampling of fluids, comprises a base and a lid. Between the base and the lid there is provided an opening and a first open-sided channel extending from the opening to a second open-sided channel for the collection of fluid therein. The depth of the second channel is smaller than that of the first channel.
    Type: Application
    Filed: August 12, 2002
    Publication date: February 12, 2004
    Applicant: Bayer Corporation
    Inventors: Neil Pollock, Richard Wilhelm Janse Van Rensburg
  • Liquid sulfur-containing oligosiloxanes and their use in rubber mixtures
    Patent number: 6689834
    Abstract: The invention relates to sulfur-containing oligosiloxanes which are liquid at −25-100° C., processes for their preparation and their use in silica-containing rubber mixtures which can be crosslinked with sulfur.
    Type: Grant
    Filed: September 7, 2001
    Date of Patent: February 10, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jürgen Ackermann, Hermann-Josef Weidenhaupt, Stefan Grabowski
  • Molded cross vehicle beam
    Patent number: 6688680
    Abstract: A molded cross vehicle beam which includes a hollow blow molded thermoplastic rigid member that is integrally attached to a rigid support, e.g., a U-shaped metal plate, and at least one attachment element, is described. The rigid support (12) has a first surface, a second surface and a plurality of perforations having edges. The attachment element(s) (81, 84) have a first surface, a second surface and a plurality of perforations having edges. The attachment element provides a manner of attaching the molded cross vehicle beam to a separate structure (e.g., the A-pillars of an automobile). A thermoplastic parison precursor of the hollow rigid thermoplastic member (15) is blow molded against the first surfaces of the rigid support (12) and the attachment element (81, 84).
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: February 10, 2004
    Assignee: Bayer Polymers LLC
    Inventors: Christopher Cooper, Olaf J. Zoellner
  • Chromatographic separation of enantiomers of lactones
    Patent number: 6689889
    Abstract: The present invention relates to the use of optically active polymers of N-acryloyl-phenylalanine neomenthylamide as such, in crosslinked form and/or in carrier-bonded form as stationary phases for the chromatographic separation of enantiomers of lactones.
    Type: Grant
    Filed: January 10, 2001
    Date of Patent: February 10, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Walter Lange, Rolf Grosser, Burkhard Köhler, Stefan Michel, Bruno Bömer, Uwe Zweering
  • Process for producing yellow iron oxide pigments
    Patent number: 6689206
    Abstract: The present invention relates to a process for producing a yellow iron oxide pigments comprising the steps of I) mixing preprecipitated FeCl2 and an &agr;-FeOOH nucleus produced by the “alkali” process, II) oxidizing the suspension in a first oxidation step at 20 to 45° C. III) oxidizing the suspension in a first oxidation step at 55 to 85° C.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: February 10, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventor: Ulrich Meisen
  • Method and device for producing bisphenol a prills and bisphenol a prills produced according to this method
    Patent number: 6689464
    Abstract: A method for producing bisphenol A in prill form is disclosed. Molten bisphenol is top-fed into a prilling tower via a plate containing a plurality of nozzles. A gas coolant guided through a circuit is led into said tower in a counter flow direction. The prills are cooled to about room temperature, collected at the bottom of the tower and removed. Also disclosed is the device for carrying out the inventive method and the prills thus produced.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: February 10, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rolf Lanze, Alfred Eitel, Rainer Neumann, Steffen Kühling, Frieder Heydenreich, Tony van Osselaer, Rainer Bellinghausen, Heiko Herold
  • Polynucleotide molecules encoding proteins having proteinase inhibitor activity
    Patent number: 6689582
    Abstract: BTL.010 is a novel human serine proteinase inhibitor of the Kunitz family that exhibits greater potency towards neutral serine proteinases, particularly leukocyte elastase and proteinase 3 than towards trypsin-like proteinases. BTL.010, or variants thereof, may be employed as therapeutics in diseases such as emphysema, idiopathic pulmonary fibrosis, adult respiratory distress syndrome, cystic fibrosis, rheumatoid arthritis, organ failure, and glomerulonephritis in which uncontrolled proteolysis due to neutral serine proteinase activity results in tissue damage.
    Type: Grant
    Filed: May 12, 2000
    Date of Patent: February 10, 2004
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Christopher Davies, Dadong Chen, Steve Roczniak
  • Substituted pyridines and pyridazines with angiogenesis inhibiting activity
    Patent number: 6689883
    Abstract: Substituted pyridazines having angiogenesis inhibiting activity and the generalized structural formula wherein the ring containing A, B, D, E, and L is phenyl or a nitrogen-containing heterocycle; groups X and Y may be any of a variety of defined linking units; R1 and R2 may be defined independent substituents or together may be a ring-defining bridge; ring J may be an aryl, pyridyl, or cycloalkyl group; and G groups may be any of a variety of defined substituents. Pharmaceutical compositions containing these materials, and methods of treating a mammal having a condition characterized by abnormal angiogenesis or hyperpermiability processes using these materials are also disclosed.
    Type: Grant
    Filed: September 28, 2000
    Date of Patent: February 10, 2004
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Jacques P. Dumas, Stephen James Boyer, Julie A. Dixon, Teddy Kite Joe, Harold C. E. Kluender, Wendy Lee, Dhanapalan Nagarathnam, Robert N. Sibley, Ning Su
  • Stabilized interleukin 2
    Patent number: 6689353
    Abstract: A stable pharmaceutical preparation comprising Human interleukin-2 or a variant thereof and a stabilizing amount of histidine. A preferred formulation includes glycine and sucrose and a variant of IL-2 having a single mutation, N88R. The preferred formulation is in lyophilized form which, on reconstitution with an aqueous diluent, results in a solution having a pH ranging from about 5.0 to 6.5.
    Type: Grant
    Filed: June 28, 2000
    Date of Patent: February 10, 2004
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Wei Wang, Rajiv Nayar, Michael A. Shearer
  • Process and device for producing foam using carbon dioxide dissolved under pressure
    Patent number: 6689325
    Abstract: A process is described for producing foam materials from two-component reactive plastics using carbon dioxide as blowing agent by mixing at least one of the reactive components with carbon dioxide under pressure, mixing the components, at least one of which contains carbon dioxide under pressure, expanding the reactive mixture containing carbon dioxide obtained by mixing, and hardening, wherein the expansion takes place suddenly with the production of high rates of shear. Preferably the rate of flow of the reaction mixture is reduced after expansion.
    Type: Grant
    Filed: April 23, 1998
    Date of Patent: February 10, 2004
    Assignees: Bayer Aktiengesellschaft, Hennecke GmbH
    Inventors: Ferdinand Althausen, Reiner Raffel, Wilfried Ebeling, Robert Eiben