Abstract: The invention relates to a device (1) for delivering two predetermined doses of a product (3), comprising: —a container (2) for containing said product, said container having a distal end (2d) through which the product is delivered under the distal pressure of a piston, —a pusher (7) movable with respect to said container for causing said piston (4) to move in the distal direction from an initial position, in which none of said product has been expelled to a first position, in which a first dose of said product has been expelled, and to a second position, in which a second dose of said product has been expelled, —a holder body (15) receiving said container and said pusher (7), —biasing means (22) for urging said pusher (7) in the distal direction, from the initial to the first position, and to the second position, —first and second retaining means (9, 11, 19) for maintaining said pusher (7) in said initial position, and in said first position, —first and second actuation means (18) to deactivate said first an

Abstract: The present invention relates to a package for a container comprising a tubular barrel having open distal and proximal ends, the proximal end being sized and shaped to receive a plunger, and the distal end being sized and shaped to receive an injection needle, said package comprising a plunger rod for said container, a part of said plunger rod being shaped complementarily to at least a part of the external shape of said tubular barrel, and a tray connectable to said plunger rod, said tray and said plunger rod forming said package when they are connected to each other. The invention further relates to a drug delivery device comprising a container and such a package.

Abstract: The invention relates to a piston rod for an injection device, comprising a first and a second legs, each leg being foldable on itself and comprising a proximal region, said piston rod being in one of a folded position and an unfolded position, said piston rod comprising coupling means for coupling the proximal region of the first leg to the proximal region of the second leg when said piston rod is in said unfolded position. The invention also relates to a kit comprising said piston rod.

Abstract: The present invention relates to an injection device including a container, intended for receiving a product and provided with an injection needle and a housing receiving the container. The container is movable relative to the housing between an initial position, an insertion position, and a final position. A collapsible chamber is defined within the housing outside of the container. The chamber is collapsible with the container in the insertion position. The chamber is at least partially defined by a proximal wall and a seal element, wherein, with the container in the initial position, the proximal wall is spaced proximally from the seal element, wherein, with the container in the insertion position, the proximal wall is caused to engage the seal element, and, wherein, with the proximal wall engaging the seal element, the container is caused to move from the insertion position to the final position.

Abstract: The present invention relates to a device for automatic injection of a product, comprising: a body (3) housing a container, the container being movable relative to said body between an initial position, to an insertion position; a safety shield (26) movable with respect to said container and said body between an insertion position to a protection position, when the user removes the device from an injection site; an external socket (48) receiving the body and provided with selection means (53) which can be placed by a user: either in a first position, in which the body (3) and the external socket (48) are bound to each other, the safety shield extending beyond the distal end of both said body and said external socket in the protection position; or in a second position, in which the external socket (48) is able to move axially in the distal direction with respect to the body (3), both the safety shield and the external socket extending beyond the distal end of said body, in the protection position.

Abstract: This packaging comprises a grouping nest for receiving the syringes, a packaging tub, and a sealing cover for sealing this packaging tub. According to the invention, the packaging comprises a plate intended to be positioned closed to the flanges of the syringe bodies before sealing of the tub; this plate comprises at least a first surface intended to be placed in contact with the flanges and at least a second surface located on the side of the cover plate opposite this first surface, the distance between said first surface and said second surface being chosen in such a way that, when the first surface lies against the flanges, the second surface is in contact or in close proximity of the said sealing cover.

Abstract: A plate with housings for receiving objects for bulking, each housing being delimited by lateral walls and comprising a support zone for receiving the object for bulking. Each housing is formed by a cell with the lateral walls delimiting the cells adjoining one another from one cell to an adjacent cell and extending in a direction substantially perpendicular to the plane of the plate. Each cell is shaped to at least partially receive the proximal part of an object for bulking and each cell immobilizes each object for bulking.

Abstract: The invention relates to an automatic injection device (1) for a product contained in a container (50), comprising: a housing (8, 19) receiving the container (50), the container being movable between an initial position and an insertion position, triggering means (23) for initiating the movement of said container (50) from its initial position to its insertion position, said triggering means (23) being in one of a passive state, in which application of a force on said triggering means does not initiate movement of said container (50), and an active state, in which application of said force on said triggering means does initiate said movement, and a safety shield (10) movable with respect to said housing (8, 19) between a first position and a second position, movement of said safety shield (10) from its first position to its second position placing said triggering means (23) in its active state, characterized in that said device comprises: an indicator (19c, 13) that provides an indication to a user of the

Abstract: A tray for positioning elongated objects each having a body and a flange. The tray includes a plate with openings and bearing surfaces. At least one first bearing surface is near a first opening and located at a first distance from the plate of the tray, and at least one second bearing surface is near a second opening adjacent the first opening and located at a second distance from the plate of the tray. The second distance is different from the first distance. The first and second openings are located at a distance with respect to one another such that the flange of a first elongated object engaged in one of these openings is able to partially overlap the flange of a second elongated object engaged in the other of these openings without contact between the flange of the first elongated object and the flange of the second elongated object.

Abstract: The present invention relates to a drug delivery device defining a reservoir for containing a product, having a distal end comprising an end-piece defining a channel for the transfer of the product from the reservoir, said drug delivery device comprising means for coupling said end-piece with a connector, said coupling means comprising a collar defined around a portion of the end-piece and extending from the distal end, said coupling means comprising connection means connectable to said collar, said connection means comprising a tubular wall portion having an interface defined thereon for engagement with an internal face of said collar, and a retaining hook having engagement means engageable with at least part of an external face of said collar when said connection means is connected to said collar.

Abstract: A container containing a therapeutic protein, characterized in that chaperones molecules are bound by a molecular linker to an inner surface of the container. The linker being interposed between the surface and the chaperone.

Abstract: The present invention relates to a device for automatic injection of a product into an injection site, the device comprising: a container having a displaceable piston; a tubular housing having at least a flexible part which, in a rest state, defines a first opening; a piston rod; and, an intermediate part fixed to the piston rod which defines a diameter larger than the first opening. With sufficient distal displacement of the piston rod, the intermediate part causes the at least a flexible part to deflect outwardly with further distal displacement of the piston rod causing the intermediate part to wholly pass through the first opening with the at least a flexible part returning towards the at rest state, engagement of the at least a flexible part with a surrounding element under force of movement towards the at rest state generating a sound.

Abstract: The application relates to a needle protection assembly (1) comprising a support (2), a needle shield (8), urging means (10) located between said support (2) and said needle shield (8), tending to displace said needle shield (8) distally over said needle (3), wherein the assembly comprises one abutment (5) provided on said support (2), receiving a locking element (10a), a part of said urging means being laterally movable with respect to said support (2) and forming part of said locking element (10a).

Abstract: The present invention relates to a method for marking a container comprising at least a transparent wall comprising the following steps: a) applying at least one spot of ink on an outer surface of said transparent wall, b) heating said transparent wall, c) engraving a data matrix in the spot of ink of said transparent wall. The invention also relates to a marked container and to a method for identifying such a marked container.

Abstract: A syringe assembly having an exterior surface and defining a chamber having a stopper disposed therein is disclosed. The syringe assembly includes a plunger assembly having an elongated plunger rod and a handle portion connected thereto, the plunger rod including a depending leg and at least one hinge connecting the depending leg with the handle portion. The plunger rod is adapted to transition from a collapsed position, in which at least a portion of the depending leg extends along at least a portion of the exterior surface of a syringe barrel, to an extended position in which at least a portion of the depending leg engages the stopper. The at least one hinge maintains the depending leg substantially parallel to a longitudinal axis of the syringe barrel in both the collapsed position and the extended position.

Abstract: A syringe assembly including a plunger rod having a first end, a second end, and a rod portion extending therebetween, wherein at least a portion of the rod portion is flexible is disclosed. The flexible portion of the rod portion allows a stopper to be moved between a first position and a second position within a syringe barrel while the overall length of the syringe assembly remains the same throughout the movement between the first position and the second position. In another embodiment, a syringe assembly including a restraining member adapted to communicate with the flexible portion of the rod portion such that movement of the first end of the plunger rod in a first direction actuates movement of the second end of the plunger rod in a second direction different than the first direction is disclosed.

Abstract: A syringe assembly includes a syringe barrel defining a chamber and having a stopper disposed within the chamber, a sleeve having a first end and a second end and extending at least partially about the syringe barrel, and a cap associated with a second end of the sleeve. The syringe assembly also includes a plunger rod having a first end associated with the cap and a second end, wherein the plunger rod is transitionable from a pre-use position, in which at least a portion of the second end of the plunger rod extends along a portion of a barrel sidewall, to a ready-to-use position in which the plunger rod is aligned with the stopper. Upon proximal movement of the sleeve in a direction away from a first end of the barrel, the plunger rod is configured for lateral movement with respect to the cap into the ready-to-use position.

Abstract: A syringe assembly including a syringe barrel defining a chamber having a stopper therein is disclosed. The syringe assembly includes a plunger rod associated with the stopper, the plunger rod includes an outer sleeve having a distal end interconnected to the stopper and a sidewall portion defining an opening therein. The plunder rod also includes an inner sleeve disposed within the outer sleeve including a longitudinally extending track in alignment with the opening in the outer sleeve. The inner sleeve is adapted for telescopic movement with respect to the outer sleeve. The plunger rod also includes a spring mounted in association with the inner sleeve. The syringe assembly further includes a holding mechanism associated with the plunger rod and configured for cooperation with the inner and outer sleeves. Relative movement between the inner and outer sleeves causes the plunger rod to transition from a collapsed position to an extended position.

Abstract: A syringe assembly includes a syringe barrel having a first end, a second end, and a sidewall extending between the first end and the second end. The syringe assembly further includes a stopper disposed within a chamber of the syringe barrel, a plunger adapter engaged with the stopper, and a plunger rod having first and second ends. The first end of the plunger rod is pivotally secured to the plunger adapter. The plunger rod has a pre-use position where the second end of the plunger rod is positioned adjacent to the syringe barrel, and a use position where the plunger rod is configured to displace the stopper relative to the syringe barrel. A recessed portion of the plunger adapter receives a portion of the first end of the plunger rod when the plunger rod is in the pre-use position and the use position.