Patents Assigned to Board of Regents The University of Texas System
  • Publication number: 20200204275
    Abstract: Disclosed are various embodiments that enable the identification of the location of a computing device based on radio data. A radio map can be identified for an area. The computing device can measure signal strengths to reference points. The signal strengths can be compared to the radio map. The computing device can determine its location based on the comparison of the signal strengths to the radio map.
    Type: Application
    Filed: November 26, 2019
    Publication date: June 25, 2020
    Applicant: Boards of Regents, The University of Texas System
    Inventors: Ali Khalajmehrabadi, Nikolaos Gatsis, David Akopian
  • Publication number: 20200201997
    Abstract: Memory allocation techniques may provide improved security and performance. A method may comprise mapping a block of memory, dividing the block of memory into a plurality of heaps, dividing each heap into a plurality of sub-heaps, wherein each sub-heap is associated with one thread of software executing in the computer system, dividing each sub-heap into a plurality of bags, wherein each bag is associated with one size class of objects, creating an allocation buffer and a deallocation buffer for each bag, storing a plurality of objects in at least some of the bags, wherein each object is stored in a bag having size class corresponding to a size of the object, storing in the allocation buffer of each bag information relating to available objects stored in that bag, and storing in the deallocation buffer of each bag information relating to freed objects that were stored in that bag.
    Type: Application
    Filed: October 18, 2019
    Publication date: June 25, 2020
    Applicant: The Board of Regents of The University of Texas System
    Inventors: Tongping Liu, Sam Albert Silvestro, Hongyu Liu, Tianyi Liu
  • Publication number: 20200197306
    Abstract: Provided herein are cationic liquid crystalline nanoparticles (CLCNs). Further provided herein are methods of delivering RNAi using the CLCNs for the treatment of diseases.
    Type: Application
    Filed: June 7, 2018
    Publication date: June 25, 2020
    Applicant: Board of Regents, The University of Texas System
    Inventors: Emanuela GENTILE, Ji LIN, Jack A. ROTH
  • Publication number: 20200200755
    Abstract: The present invention provides that exosomes from human body fluid samples contain double stranded genomic DNA that spans all chromosomes and may be used to determine the mutation status of genes of interest in diseases, such as cancer. Furthermore, the present invention provides the use of exosomes to produce therapeutic proteins and for their use in therapy as well as the detection of cancer cell-derived exosomes to diagnose cancer and monitor therapeutic response.
    Type: Application
    Filed: March 4, 2020
    Publication date: June 25, 2020
    Applicant: Board of Regents, The University of Texas System
    Inventors: Raghu KALLURI, Sónia MELO
  • Publication number: 20200197300
    Abstract: The present invention provides a formulation of Coenzyme Q10 that can be re-dispersed from a stable dry powder to formulation to yield a nanodispersion that can be readily aerosolized for inhalation.
    Type: Application
    Filed: January 30, 2020
    Publication date: June 25, 2020
    Applicants: STC.UNM, RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Jason Thomas McConville, Thiago Cardoso Carvalho, Kristina Schönhoff
  • Publication number: 20200200929
    Abstract: Systems and methods for simulating subterranean regions having multi-scale fracture geometries. Non-intrusive embedded discrete fracture modeling formulations are applied in conjunction with commercial simulators to efficiently and accurately model subsurface transient flow characteristics in regions having complex hydraulic fractures, complex natural fractures, or a combination of both, and geometries including corner point grids.
    Type: Application
    Filed: December 2, 2019
    Publication date: June 25, 2020
    Applicants: Sim Tech LLC, Board of Regents, The University of Texas System
    Inventors: Kamy Sepehrnoori, Yifei Xu, Wei Yu, Jijun Miao
  • Patent number: 10689526
    Abstract: The present invention is a composition and method for making and using a rechargeable multifunctional additive that reduce the formation of biofilms on a surface, the additive can also remain photo and thermally stable by synthesizing one or more N-halamine compounds and adding one or more N-halamine biocidal compounds to a target material prior, during or after the target material is made. The resultant material can be used directly to provide antimicrobial functions and control biofilm formation, or the material can be further processed into an article.
    Type: Grant
    Filed: October 22, 2018
    Date of Patent: June 23, 2020
    Assignee: Board of Regents, The University of Texas System
    Inventors: Yuyu Sun, Zhaobin Chen
  • Patent number: 10687953
    Abstract: In one embodiment, an anterior cervical transarticular fixation implant including a cervical plate including a central body, lateral wings that extend laterally outward from the central body, each lateral wing including a fastener opening configured to receive a fastener configured to thread into vertebrae, and locking mechanisms configured to selectively lock the fasteners in place.
    Type: Grant
    Filed: February 19, 2018
    Date of Patent: June 23, 2020
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Kenrick Chur-wei Lam, Sohum Desai, Daniel Williams Branch
  • Patent number: 10691095
    Abstract: Methods and systems for diagnosing and controlling material deposition during a material extrusion 3D printing process. A current sensor can measure a current signal consumed by a material feed motor. The current signal can be analyzed in the time domain and frequency domain to detect material deposition characteristics and prescribe process parameter changes.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: June 23, 2020
    Assignee: Board of Regents, The University of Texas System
    Inventors: Chi Yen Kim, David Espalin, Eric MacDonald, Ryan Wicker
  • Patent number: 10687520
    Abstract: Duchenne muscular dystrophy (DMD), which affects 1 in 5,000 male births, is one of the most common genetic disorders of children. This disease is caused by an absence or deficiency of dystrophin protein in striated muscle. The major DMD deletion “hot spots” are found between exon 6 to 8, and exons 45 to 53. Here, a “humanized” mouse model is provided that can be used to test a variety of DMD exon skipping strategies. Among these are, CRISPR/Cas9 oligonucleotides, small molecules or other therapeutic modalities that promote exon skipping or micro dystrophin mini genes or cell based therapies. Methods for restoring the reading frame of exon 44 deletion via CRISPR-mediated exon skipping in the humanized mouse model, in patient-derived iPS cells and ultimately, in patients using various delivery systems are also contemplated. The impact of CRISPR technology on DMD is that gene editing can permanently correct mutations.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: June 23, 2020
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Yi-Li Min, Rhonda Bassel-Duby, Eric Olson
  • Patent number: 10688203
    Abstract: In one aspect, radioactive nanoparticles are described herein. In some embodiments, a radioactive nanoparticle described herein comprises a metal nanoparticle core, an outer metal shell disposed over the metal nanoparticle core, and a metallic radioisotope disposed within the metal nanoparticle core or within the outer metal shell. In some cases, the radioactive nanoparticle has a size of about 30-500 nm in three dimensions. In addition, in some embodiments, the radioactive nanoparticle further comprises an inner metal shell disposed between the metal nanoparticle core and the outer metal shell. The metal nanoparticle core, outer metal shell, and inner metal shell of the radioactive nanoparticle can have various metallic compositions.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: June 23, 2020
    Assignee: Board of Regents, The University of Texas System
    Inventors: Xiankai Sun, Yaowu Hao, Sina Moeendarbari
  • Publication number: 20200190204
    Abstract: Provided herein are BAFF-R antibodies as well as compositions and methods of making and using the same. The antibodies provided herein are, inter alia, useful for the treatment of cancer and autoimmune diseases.
    Type: Application
    Filed: June 6, 2017
    Publication date: June 18, 2020
    Applicants: CITY OF HOPE, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Hong QIN, Larry W. KWAK, Jingxing LI, Kexin HUANG
  • Publication number: 20200188396
    Abstract: Certain embodiments are directed to methods of treating or preventing an addictive behavior in a subject by administering to the subject an effective amount of a 5-HT2C receptor agonist in combination with a DA D3/D4 receptor antagonist.
    Type: Application
    Filed: April 27, 2018
    Publication date: June 18, 2020
    Applicant: The Board of Regents of The University of Texas System
    Inventors: Charles France, Gregory Collins
  • Publication number: 20200189933
    Abstract: Disclosed are a desalination device and processes of desalination using the device. The device is directly ocean-situated and fully nature-powered with on intake, no brine production, and no electricity consumption. The device contains a heating unit, configured to receive a dry air stream and heat the dry air stream with one or more renewable energy sources to produce a heated air stream; a humidifier, configured to receive the heated air stream, evaporate at least portion of water present in the humidifier and humidify the heated air stream to produce a wet air stream, a cooling unit, configured to receive the wet stream and cool the wet air stream resulting in condensation of at least a portion of the moisture to produce fresh water and a dehumidified air stream; and a fresh water collection tank, configured to collect at least a portion of the fresh water.
    Type: Application
    Filed: December 12, 2019
    Publication date: June 18, 2020
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventor: Yingchen Yang
  • Publication number: 20200191127
    Abstract: Actuators (artificial muscles) comprising twist-spun nanofiber yarn or twist-inserted polymer fibers generate torsional actuation when powered electrically, photonically, chemically, thermally, by absorption, or by other means. These artificial muscles utilize coiled yarns/polymer fibers and can be either neat or comprising a guest. In some embodiments, the actuator system includes a twisted and coiled polymer fiber actuator, and at least one of (i) wire connections that enable electrical heating of the twisted and coiled polymer fiber actuator, (ii) a radiation source and radiation pathway that enables photothermal heating of the twisted and coiled polymer fiber actuator, and (iii) a delivery system for delivering chemicals whose reaction produces heating of the twisted and coiled polymer fiber actuator.
    Type: Application
    Filed: October 9, 2019
    Publication date: June 18, 2020
    Applicant: Board of Regents, The University of Texas System
    Inventors: Na Li, Carter S. Haines, Marcio D. Lima, Monica Jung DeAndrade, Shaoli Fang, Jiyoung Oh, Mikhail E. Kozlov, Dongseok Suh, Ray H. Baughman
  • Patent number: 10682077
    Abstract: Devices and methods for detecting joint motion of a user. In particular embodiments, devices may comprise a deflectable beam coupled to a user via adhesive pads located between the neck and shoulder of the use. Audio and haptic feedback can be provided to the user when the deflectable beam deflects due to motion of the joint.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: June 16, 2020
    Assignees: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, SETON HEALTHCARE FAMILY
    Inventors: James S. Sulzer, Jose J. Mendez, Jr., Nicholas D. Phillips, Lisa Stevens, Curtis Merring
  • Patent number: 10682388
    Abstract: The disclosure describes PELP1 binding peptides and peptoids and their use the interaction of PELP1 with molecules that lead to oncogenic signaling in cancers.
    Type: Grant
    Filed: January 14, 2015
    Date of Patent: June 16, 2020
    Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Ratna K. Vadlamudi, Monica Mann, Samaya Krishnan, Gangadhara Reddy Sareddy
  • Patent number: 10683582
    Abstract: In some embodiments, an anti-corrosive composite ceramic coating includes an inner metal layer formed on the surface of a metal object to be protected and an outer composite ceramic layer formed on the inner metal layer.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: June 16, 2020
    Assignee: Board of Regents, The University of Texas System
    Inventors: George Kenneth Rice, Miguel Jose Yacaman, Ekaterina Vinogradova
  • Patent number: 10687329
    Abstract: Various examples are provided for coherence diversity. In one example, a method includes receiving a product signal transmitted over a plurality of subcarriers, the product signal including a product superposition of a first baseband signal and a second baseband signal; estimating equivalent channel responses for the plurality of subcarriers based upon the pilot symbol in the number of time slots of the plurality of subcarriers; and decoding the second encoded message based at least in part upon the first baseband signal and the equivalent channel responses. The first baseband signal can include a pilot symbol in a number of time slots of at least a portion of the plurality of subcarriers and a first encoded message in a remaining number of time slots of the plurality of subcarriers, and the second baseband signal can include a second encoded message.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: June 16, 2020
    Assignee: Board of Regents, The University of Texas System
    Inventors: Aria Nosratinia, Mohamed Fadel Shady
  • Patent number: 10682339
    Abstract: Embodiments of the current invention include methods and compositions for regulating the activity of hormone receptors.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: June 16, 2020
    Assignees: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, THE UNIVERSITY OF BRITISH COLUMBIA
    Inventors: Marc Cox, Artem Cherkasov