Abstract: Systems and methods for providing an electrical interface to a body are provided. In one embodiment, an implantable module is disclosed, comprising: an implantable electrode array, implantable within a body and capable of providing a plurality of communication channels for communicating electrical signals detected in a body; an amplifier circuit for processing electrical signals received from the electrode array; a wireless transceiver for sending and receiving telemetry data between the amplifier circuit and a wireless receiver located outside of the body; and a sealed enclosure that houses the amplifier circuit and the wireless transmitter and is biocompatible with surrounding tissue, the enclosure having a window that is transparent to a wireless medium used by the wireless transceiver.

Abstract: Ratio of neutrophils to lymphocytes (NLR) is here associated with immune suppression and decreased survival times in multiple solid tumors. Based on immune cell-specific DMRs and validated cell deconvolution algorithms, the NLR in blood from glioma patients was estimated and glioma patients had elevated mdNLR scores compared to controls. The patient mdNLR scores were increased in patients with grade IV tumors compared to grade II/III. High mdNLR scores were associated with shorter survival. Candidate single (myeloid-associated) gene loci that were highly correlated with the mdNLR were identified. Single myeloid differentiation loci provide a simpler and cheaper alternative to the mdNLR, which requires complex array data. Immunomethylomics are useful and more convenient than conventional cell analysis in profiling glioma risk and survival.

Abstract: The invention is a computer implemented method, device, system, or article for reconstructing a surface of an object. In particular, the invention comprises estimating a non-convex hull signed distance function parameters from a data set of an object and evaluating the non-convex hull signed distance function on vertices of a volumetric mesh. The invention further comprises approximating the zero level set of the non-convex hull signed distance function by a polygonal mesh using an isosurface algorithm to provide surface reconstruction of an object.

Abstract: In embodiments, secure compression algorithms are provided that may be employed as a single operation on raw data to produce compressed and encrypted data. In embodiments, the algorithms described herein may be performed using any type of dictionary based encryption. In one embodiment, upon adding a new prefix to a dictionary table, the dictionary table may be permuted to randomize the entries into the table. The randomization may be based upon a permutation value generated by a deterministic pseudo-random generator and/or pseudo-random function. Other embodiments of randomization may be employed to provide secure compression. For example, instead of permuting the entire table upon adding a prefix, the prefix may be randomly added to the table.

Abstract: A method and apparatus to manufacture a coherent bundle of scintillating fibers is disclosed. A method includes providing a collimated bundle having a glass preform with capillaries therethrough known in the industry as a glass capillary array, and infusing the glass capillary array with a scintillating polymer or a polymer matrix containing scintillating nanoparticles.

Abstract: Disclosed are computer-readable devices, systems and methods for generating a model of a clothed body. The method includes generating a model of an unclothed human body, the model capturing a shape or a pose of the unclothed human body, determining two-dimensional contours associated with the model, and computing deformations by aligning a contour of a clothed human body with a contour of the unclothed human body. Based on the two-dimensional contours and the deformations, the method includes generating a first two-dimensional model of the unclothed human body, the first two-dimensional model factoring the deformations of the unclothed human body into one or more of a shape variation component, a viewpoint change, and a pose variation and learning an eigen-clothing model using principal component analysis applied to the deformations, wherein the eigen-clothing model classifies different types of clothing, to yield a second two-dimensional model of a clothed human body.

Abstract: An apparatus for a lead-free piezoelectric ink-jet printhead is disclosed. Piezoelectric printheads, while more expensive are favored because they use a wider variety of inks. The piezoelectric printhead includes a diaphragm, a plurality of piezoelectric actuators comprising a lead-free piezoelectric material, at least one nozzle, at least one ink chamber, a top electrode, and a drive circuit. The deflection of the diaphragm on the body chamber contributes to a pressure pulse that is used to eject a drop of liquid from the nozzle. According to an exemplary embodiment, a lead-free piezoelectric printhead operated at smaller thicknesses and significantly higher electric fields is disclosed, along with methods of making such printheads.

Abstract: The present invention is directed to transfection complexes of rosette nanotubes and one or more nucleic acids.

Abstract: A method and apparatus to manufacture a coherent bundle of scintillating fibers is disclosed. A method includes providing a collimated bundle having a glass preform with capillaries therethrough known in the industry as a glass capillary array, and infusing the glass capillary array with a scintillating polymer or a polymer matrix containing scintillating nanoparticles.

Abstract: A system generates a clothing deformation model which models one or more of a pose-dependent clothing shape variation which is induced by underlying body pose parameters, a pose-independent clothing shape variation which is induced by clothing size and underlying body shape parameters and a clothing shape variation including a combination of the pose-dependent clothing shape variation and/or the pose-independent clothing shape variation. The system generates, for an input human body, a custom-shaped garment associated with a clothing type by mapping, via the clothing deformation model, body shape parameters of the input human body to clothing shape parameters of the clothing type and dresses the input human body with the custom-shaped garment.

Abstract: The present invention is directed to transfection complexes of rosette nanotubes and one or more nucleic acids.

Abstract: A system and method of estimating the body shape of an individual from input data such as images or range maps. The body may appear in one or more poses captured at different times and a consistent body shape is computed for all poses. The body may appear in minimal tight-fitting clothing or in normal clothing wherein the described method produces an estimate of the body shape under the clothing. Clothed or bare regions of the body are detected via image classification and the fitting method is adapted to treat each region differently. Body shapes are represented parametrically and are matched to other bodies based on shape similarity and other features. Standard measurements are extracted using parametric or non-parametric functions of body shape. The system components support many applications in body scanning, advertising, social networking, collaborative filtering and Internet clothing shopping.

Abstract: Systems, compositions, methods and kits employ protein shells, such as ferritin or viral capsid shells, herein called nanobubbles, to enhance X-ray images of cells or body tissue under certain x-ray imaging methods. The nanobubbles have sub-micron size such as about 10 nm, about 40, 60, or 100 nm and may be functionalized for effective delivery to or uptake by a target tissue, in vivo or a cell culture. The nanobubbles are hollow, having a central core which may be empty or contain a fluid, such that the shells effectively form long-lived bubbles in the imaged environment, and are of low electron density and have different scattering properties than the surrounding tissue. X-ray imaging by spatial frequency heterodyne imaging enhances visualization or detection of tissue regions bearing the shells. The protein shells may be further treated to assure biocompatibility and/or to resist undesired interactions with non-targeted tissue, such as scavenging by the liver, or attack by the immune system.

Abstract: Methods, devices, and compositions for use with spintronic devices such as magnetic random access memory (MRAM) and spin-logic devices are provided. Methods include manipulating magnetization states in spintronic devices and making a structure using spin transfer torque to induce magnetization reversal. A device described herein manipulates magnetization states in spintronic devices and includes a non-magnetic metal to generate spin current based on the giant spin Hall effect, a ferromagnetic thin film with perpendicular magnetic anisotropy, an oxide thin film, and an integrated magnetic sensor. The device does not require an insertion layer between a non-magnetic metal with giant spin Hall effect and a ferromagnetic thin film to achieve perpendicular magnetic anisotropy.

Abstract: An automated infant cry analyzer with high accuracy to detect important acoustic features of cry is provided. The system's accuracy was rigorously tested and was compared to ground truth manual coding. The resulting methods and systems are applied to infant developmental disorders.

Abstract: A system for high-speed molecular diagnostics includes a self-resetting continuous-time integrator configured to integrate an input current on one of a plurality of integration capacitors to generate an integrated voltage. A self-resetting continuous-time differentiator is configured to differentiate the integrated voltage on one of a plurality of differentiating capacitors to generate an output voltage proportional to the input current. A fixed-threshold window comparator is configured to reset one of the plurality of integration capacitors, reset one of the plurality of differentiating capacitors, open a second one of the plurality of integration capacitors and open a second one of the plurality of differentiating capacitors in response to the integrated voltage exceeding a voltage range.

Abstract: Described herein are methods and compositions relating to anti-Chi3L1 antibodies, antibody reagents, and antigen-binding fragments thereof which display superior properties, e.g., high sensitivity, high specificity, high binding affinity, neutralization activity ex vivo and in vivo (e.g., blocks Chi3L1-induced MAPK and AKT signaling). Methods of treatment, e.g., of treating cancer, obesity, and/or asthma by administering the compounds described herein are also provided.

Abstract: Described herein are methods and compositions relating to anti-Chi3L1 antibodies, antibody reagents, and antigen-binding fragments thereof which display superior properties, e.g., high sensitivity, high specificity, high binding affinity, neutralization activity ex vivo and in vivo (e.g., blocks Chi3L1-induced MAPK and AKT signaling). Methods of treatment, e.g., of treating cancer, obesity, and/or asthma by administering the compounds described herein are also provided.

Abstract: An apparatus for a lead-free piezoelectric ink-jet printhead is disclosed. Piezoelectric printheads, while more expensive are favored because they use a wider variety of inks. The piezoelectric printhead includes a diaphragm, a plurality of piezoelectric actuators comprising a lead-free piezoelectric material, at least one nozzle, at least one ink chamber, a top electrode, and a drive circuit. The deflection of the diaphragm on the body chamber contributes to a pressure pulse that is used to eject a drop of liquid from the nozzle. According to an exemplary embodiment, a lead-free piezoelectric printhead operated at smaller thicknesses and significantly higher electric fields is disclosed, along with methods of making such printheads.

Abstract: The invention provides a catalyst and method for producing hydrocarbons from a carbon dioxide source comprising carbides, in particular one or more metal carbides. The one or more metal carbides are formed with one or more elements selected from the group consisting of molybdenum, titanium, tungsten, iron, and tantalum. In one embodiment, the one or more metal carbides are nanostructures. In another embodiment, the one or more metal carbide nanostructures are supported by a carbon substrate. In a further embodiment, the one or more metal carbides nanostructures is dimolybdenum carbide. In still another embodiment, the carbon substrate is graphene or graphene oxide. In another embodiment, the dimolybdenum carbide nanostructures are supported by the graphene or graphene oxide substrate.