Abstract: The present invention relates to a method for preparing etelcalcetide hydrochloride (etelcalcetide HCL). A first peptide is de-protected and cleaved from a solid support by a first solution system, for obtaining a second peptide, followed by coupling an activated L-Cys-OH to the second peptide in the second solution system for forming a TFA salt of etelcalcetide that is not or hardly dissolved in the second solution system. After purification by column chromatography, the TFA salt of etelcalcetide can be converted to etelcalcetide HCL using a third solution system that excludes hydrogen chloride during a real-time monitoring salt exchange step. The present method provides a simplified process and the etelcalcetide HCL with high purity and yield, for being advantageously applied in mass production of etelcalcetide HCL.

Abstract: A stretchable display device includes a lower substrate; a plurality of first substrates which is disposed on the lower substrate and includes a first area in which a plurality of sub pixel including a display element and a driving element is disposed and a second area excluding the first area; a plurality of second substrates configured to couple adjacent first substrates among the plurality of first substrates; and a plurality of connection lines which are disposed on the plurality of second substrates and are configured to couple the plurality of sub pixels, and in the second area, a first contact pad and a second contact pad are disposed and the first contact pad and the second contact pad are coupled to the plurality of connection lines via a plurality of contact holes.

Abstract: A multi-channel audio signal coding method includes obtaining a to-be-encoded first audio frame, pairing at least five channel signals according to a first pairing manner to obtain a first channel pair set, obtaining a first sum of correlation values of the first channel pair set, where one channel pair has one correlation value, pairing the at least five channel signals according to a second pairing manner to obtain a second channel pair set, obtaining a second sum of correlation values of the second channel pair set, determining a target pairing manner of the at least five channel signals based on the first sum of correlation values and the second sum of correlation values, and encoding the at least five channel signals based on a channel pair set corresponding to the target pairing manner, where the target pairing manner is the first pairing manner or the second pairing manner.

Abstract: A control method and a control device applied to an electric fracturing apparatus are provided. The electric fracturing apparatus includes a plunger pump and a first motor configured to drive the plunger pump, and the method includes: acquiring a preset displacement of the plunger pump; acquiring a rotation speed of the first motor and a discharge pressure of the plunger pump; determining a real-time displacement of the plunger pump based on the rotation speed of the first motor and the discharge pressure of the plunger pump and adjusting the real-time displacement; and upon the real-time displacement reaching the preset displacement, allowing the first motor to be kept in a stable operation state.

Abstract: A thin film laminate structure, an integrated device including the same, and a method of manufacturing the thin film laminate structure are provided. The thin film laminate structure includes two or more dielectric layers, wherein at least one of the dielectric layers of the thin film laminate structure includes a compound represented by Formula 1 and having a perovskite-type crystal structure having a B/B? composition ratio different from that of a remainder of the dielectric layers: AB1-xB?xO3??<Formula 1> wherein, in Formula 1, A, B, B?, and x are the same as defined in the specification.

Abstract: A semiconductor light emitting device includes a semiconductor light source, a resin package surrounding the semiconductor light source, and a lead fixed to the resin package. The lead is provided with a die bonding pad for bonding the semiconductor light source, and with an exposed surface opposite to the die bonding pad The exposed surface is surrounded by the resin package in the in-plane direction of the exposed surface.

Abstract: A thermoelectric conversion device includes: an insulating layer; and a thermoelectric conversion module disposed on the insulating layer. The thermoelectric conversion module has a first thermoelectric conversion region and a second thermoelectric conversion region. The first(second) thermoelectric conversion region includes one or two or more thermoelectric conversion elements, a first(third) connection electrode, and a second(fourth) connection electrode. The thermoelectric conversion elements of the first(second) thermoelectric conversion region are electrically connected to the first(third) connection electrode and the second(fourth) connection electrode and located on an electric path connecting these connection electrodes. Each of the thermoelectric conversion elements includes a thermoelectric converter.

Abstract: A method for designing a multi-layer optical structure includes: obtaining candidate multi-layer optical structures through a sequence generator; obtaining a candidate spectrum for each candidate multi-layer optical structure; obtaining a difference between the candidate spectrum and a target spectrum; updating sequence generator parameters through reinforcement learning training and iteratively performing the obtainings and the updating in response to a first termination condition being not met; and selecting one of all obtained candidate structures to be a target multi-layer optical structure in response to the first termination condition being met. The difference between a spectrum of the target multi-layer optical structure and the target spectrum is minimized through the process. The method of the present application can perform the designs robustly and effectively.

Abstract: A storage device includes a communication circuit and a controller. The controller is configured to transmit log data to a host device through the communication circuit in response to receiving a first signal from the host device, receive a second signal, including an operation condition of an algorithm of the storage device, from the host device through the communication circuit, and change the operation condition of the algorithm on the basis of the second signal, wherein the algorithm includes one or more instructions for controlling an operation of the storage device.

Abstract: The present disclosure provides a random access resource processing method and device. The method includes: receiving first indication information from a network device, where the first indication information is used to indicate whether a preset random access resource is available; and transmitting first acknowledgment information to the network device.

Abstract: A pendulum rocker damper with a rotation axis includes an input side with first and second input-side counter tracks, an output side with first and second output-side counter tracks, a stored energy source, and rocker elements disposed at opposite axial ends of the stored energy source. Each of the rocker elements has three axially offset partial tracks forming an input-side roller track and an output-side roller track. A first input-side rolling element is clamped between the first input-side counter track and a first input-side roller track and a second input-side rolling element is clamped between the second input-side counter track and a second input-side roller track. A first output-side rolling element is clamped between the first output-side counter track and a second output-side roller track and a second output-side rolling element is clamped between the second output-side counter track and a second output-side roller track.

Abstract: A method for generating context information for a video stream includes selecting a set of frames of a video stream, applying a first machine learning model to the set of frames to extract action information from the set of frames, applying natural language learning to the set of frames to identify dialogue associated with the set of frames, and generating context information to categorize the dialogue and action information for the set of frames.

Abstract: A driving support device is provided which can estimate the line-of-sight of an occupant with high accuracy. A driving support device 11 includes: a peripheral information acquisition unit 40 which acquires peripheral information of the periphery of a vehicle 1; a driver monitor camera 50 which acquires occupant information related to the occupant of the vehicle 1; an outside-world information detection unit 201 which detects the outside-world information including the position and speed of the target in the surroundings of the vehicle 1 based on the peripheral information; a line-of-sight estimation unit 202 which estimates the line-of-sight of the occupant of the vehicle 1 based on the occupant information; and a line-of-sight correction unit 203 which corrects the estimated line-of-sight, based on the outside-world information detected by the outside-world information detection unit 201.

Abstract: The subject application provides a portable electronic heating type device with an improved power converter topology configured for receiving a DC input voltage from the power supply and generate an AC output voltage to the heating element. The power converter is based on an inductor, a DC blocking capacitor and only one switching device. Heating power can be adjusted under a pulse-width-modulation mode, a fixed-on-time mode, a fixed-off-time mode or a frequency-modulation mode. The portable electronic heating type device has less switching loss and faster response. Therefore, it can be operated at higher frequency and more compact in size.

Abstract: A method for detecting damage to one or more components of a fluid-conducting device such as a pump assembly, valve or the like uses at least one odor sensor to detect an odor produced by one of the components and transmit an odor profile to an evaluation unit. The evaluation unit compares the odor profile with one or more characteristic odor profiles to determine whether an odor indicative of a degraded component is present. If the detected odor profile matches a characteristic odor profile match, an output signal is generated in an output unit.