Patents Assigned to Cornell University
  • Patent number: 11382368
    Abstract: An embodiment of a robotic fabric has a first fabric layer and an actuator that is configured to have a first state and a second state. A property of the first fabric layer is different when the actuator is in the first state as compared to the property of the first fabric layer when the actuator is in the second state.
    Type: Grant
    Filed: June 18, 2019
    Date of Patent: July 12, 2022
    Assignee: Cornell University
    Inventors: Jintu Fan, Dahua Shou, Yan Cui
  • Patent number: 11381159
    Abstract: The present disclosure provides a high-power-density power converter topology with a common neutral between its input and output AC ports while having a single DC bus. The topology may also be embodied as an online uninterruptible power supply (UPS). The presently-disclosed topology enables high power density by utilizing half-bridge switch structures suitable for MHz-frequency operation.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: July 5, 2022
    Assignees: Cornell University, The Regents of the University of Colorado, a body corporate
    Inventors: Khurram Afridi, Nauman Zaffar, Danish Shahzad
  • Publication number: 20220208194
    Abstract: The present disclosure describes approaches to voice restoration using personal devices that detect surface electromyographic (sEMG) signals from articulatory muscles for the recognition of silent speech in a patient (such as a patient with total laryngectomy, on voice rest, etc.). A personal device may comprise a cutaneous sensor unit and a control module that wirelessly transmits signals to a computing device capable of, for example, applying a predictive model to signals to generate text or synthesize speech. Methods and systems for training and applying predictive models, and fabricating personal devices, are disclosed.
    Type: Application
    Filed: May 28, 2020
    Publication date: June 30, 2022
    Applicant: Cornell University
    Inventors: Anais Rameau, Simon Dunham, Fei Wang
  • Publication number: 20220199782
    Abstract: Gallium nitride high-electron-mobility transistors (GaN HEMTs) are at a point of rapid growth in defense (radar, SATCOM) and commercial (5G and beyond) industries. This growth also comes at a point at which the standard GaN heterostructures remain unoptimized for maximum performance. For this reason, the shift to the aluminum nitride (AlN) platform is disclosed. AlN allows for smarter, highly-scaled heterostructure design that improves the output power and thermal management of GaN amplifiers. Beyond improvements over the incumbent amplifier technology, AlN allows for a level of integration previously unachievable with GaN electronics. State-of-the-art high-current p-channel FETs, mature filter technology, and advanced waveguides, all monolithically integrated with an AlN/GaN/AlN HEMT, is made possible with aluminum nitride. It is on this AlN platform that nitride electronics may maximize their full high-power, highspeed potential for mm-wave communication and high-power logic applications.
    Type: Application
    Filed: December 17, 2021
    Publication date: June 23, 2022
    Applicant: Cornell University
    Inventors: Austin Hickman, Reet Chaudhuri, James C. M. Hwang, Huili Grace Xing, Debdeep Jena
  • Publication number: 20220194904
    Abstract: The present technology is directed to compounds, intermediates thereof, compositions thereof, medicaments thereof, and methods related to the imaging of mammalian tissue overexpressing PSMA. The compounds are of Formula I or a pharmaceutically acceptable salt thereof, wherein one of R1, R2, and R3 is and of Formula IV or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: July 30, 2021
    Publication date: June 23, 2022
    Applicant: Cornell University
    Inventors: John W. Babich, Jasmes M. Kelly, Alejandro Amor-Coarasa, Shashikanth Ponnala
  • Publication number: 20220187677
    Abstract: A meta-optical device, which imparts a phase delay to incident light of a wavelength band, includes: a first electrode and a second electrode spaced apart from each other; a liquid crystal layer between the first electrode and the second electrode; a meta-surface layer located within the liquid crystal layer and including a plurality of nanostructures each having a shape dimension smaller than a center wavelength of the wavelength band; and a voltage device configured to apply a voltage between the first electrode and the second electrode. The meta-optical device may exhibit an electrically controlled variable focal length.
    Type: Application
    Filed: December 15, 2021
    Publication date: June 16, 2022
    Applicants: Samsung Electronics Co., Ltd., Cornell University
    Inventors: Kanghee Won, Maxim Radikovich Shcherbakov, Hongseok Lee, Melissa Bosch, Gennady Shvets
  • Publication number: 20220185803
    Abstract: The present technology provides compounds as well as compositions including such compounds useful in targeted radiotherapy of cancer and/or mammalian tissue overexpressing prostate specific membrane antigen (“PSMA”) where the compounds are represented by the following: or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, wherein M1 is independently at each occurrence an alpha-emitting radionuclide. Equivalents of such compounds are also disclosed.
    Type: Application
    Filed: February 23, 2022
    Publication date: June 16, 2022
    Applicant: Cornell University
    Inventors: John W. Babich, Justin Wilson, Nikki Thiele, James Kelly, Shashikanth Ponnala
  • Publication number: 20220177461
    Abstract: The present technology provides compounds as well as compositions including such compounds useful in targeted radiotherapy of cancer and/or mammalian tissue overexpressing prostate specific membrane antigen (“PSMA”) where the compounds are represented by the following: or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, wherein M1 is independently at each occurrence an alpha-emitting radionuclide. Equivalents of such compounds are also disclosed.
    Type: Application
    Filed: February 23, 2022
    Publication date: June 9, 2022
    Applicant: Cornell University
    Inventors: John W. Babich, Justin WILSON, Nikki THIELE, James KELLY, Shashikanth PONNALA
  • Patent number: 11353046
    Abstract: Disclosed herein are actuators and methods of making and actuating the same. Such actuators may comprise a body having a cavity, a membrane configured to cooperate with the cavity to form a combustion chamber, an inlet channel in fluid communication with the combustion chamber, an ignitor operable to ignite a combustible gas contained within the combustion chamber, and an outlet channel in fluid communication with the combustion chamber. The membrane may be configured to move in response to a change in pressure within the combustion chamber.
    Type: Grant
    Filed: August 19, 2020
    Date of Patent: June 7, 2022
    Assignee: Cornell University
    Inventors: Ronald Heisser, Robert Shepherd, Cameron Aubin
  • Publication number: 20220152228
    Abstract: Among the various aspects of the present disclosure is the provision of compositions of isotope-ligand complexes, methods of use thereof, and methods of chelating isotopes. The present disclosure also provides for methods for modulating ion channel transportation of radiopharmaceuticals. For example, the inhibition of radiopharmaceutical transport comprises administering an ion channel transport modulating or inhibiting agent (e.g., a calcium channel inhibitor) in an amount effective to inhibit gastrointestinal uptake.
    Type: Application
    Filed: March 1, 2020
    Publication date: May 19, 2022
    Applicants: Washington University, Cornell University
    Inventors: Daniel THOREK, Diane ABOU, Justin WILSON, Nikki THIELE
  • Patent number: 11318138
    Abstract: Described herein are methods for treating B cell proliferative disorders, in an individual in need thereof. The methods include administering to an individual in need thereof a Btk inhibitor (e.g., ibrutinib), in combination with a CDK4 inhibitor (e.g., palbociclib).
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: May 3, 2022
    Assignee: Cornell University
    Inventors: Selina Chen-Kiang, Maurizio Di Liberto
  • Patent number: 11318154
    Abstract: A method of preventing or treating a subject suffering from Clostiridium difficile infection or its associated symptom includes administering a therapeutic effective amount of a HMGB1 inhibitor to the subject. A method of inhibiting toxin-induced cytotoxic effect in colon cells includes contacting the colon cells with an effective amount of a HMGB1 inhibitor.
    Type: Grant
    Filed: August 15, 2019
    Date of Patent: May 3, 2022
    Assignees: City University of Hong Kong, Cornell University
    Inventors: Linfeng Huang, Yung-fu Chang, Yingxue Li, Yutian Ren, Wei Xu
  • Publication number: 20220118002
    Abstract: The present disclosure relates generally to compositions and methods for the treatment of eye diseases (e.g., retinopathies), and more particularly, to treatment of eye diseases associated with retinal cell lipofuscin accumulation.
    Type: Application
    Filed: March 3, 2020
    Publication date: April 21, 2022
    Applicant: Cornell University
    Inventors: Marcelo M. Nociari, Enrique Rodriguez Boulan
  • Publication number: 20220109051
    Abstract: Provided are a superlattice structure including a two-dimensional material and a device including the superlattice structure. The superlattice structure may include at least two different two-dimensional (2D) materials bonded to each other in a lateral direction, and an interfacial region of the at least two 2D materials may be strained. The superlattice structure may have a bandgap adjusted by the interfacial region that is strained. The at least two 2D materials may include first and second 2D materials. The first 2D material may have a first bandgap in an intrinsic state thereof. The second 2D material may have a second bandgap in an intrinsic state thereof. An interfacial region of the first and second 2D materials and an adjacent region may have a third bandgap between the first bandgap and the second bandgap.
    Type: Application
    Filed: November 1, 2021
    Publication date: April 7, 2022
    Applicants: Samsung Electronics Co., Ltd., THE UNIVERSITY OF CHICAGO, Center for Technology Licensing at Cornell University
    Inventors: Minhyun LEE, Jiwoong PARK, Saien XIE, Jinseong HEO, Hyeonjin SHIN
  • Patent number: 11285227
    Abstract: The present technology provides compounds, as well as compositions including such compounds, useful for imaging and/or treatment of a glioma, a breast cancer, an adrenal cortical cancer, a cervical carcinoma, a vulvar carcinoma, an endometrial carcinoma, a primary ovarian carcinoma, a metastatic ovarian carcinoma, a non-small cell lung cancer, a small cell lung cancer, a bladder cancer, a colon cancer, a primary, gastric adenocarcinoma, a primary colorectal adenocarcinoma, a renal cell carcinoma, and/or a prostate cancer. The compounds are represented by the following formula: (I) or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: March 29, 2022
    Assignee: Cornell University
    Inventors: John W. Babich, James M. Kelly, Alejandro Amor-Coarasa, Shashikanth Ponnala
  • Patent number: 11279698
    Abstract: The present technology provides compounds as well as compositions including such compounds useful in targeted radiotherapy of cancer and/or mammalian tissue overexpressing prostate specific membrane antigen (“PSMA”) where the compounds are represented by the following: or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, wherein M1 is independently at each occurrence an alpha-emitting radionuclide. Equivalents of such compounds are also disclosed.
    Type: Grant
    Filed: November 20, 2019
    Date of Patent: March 22, 2022
    Assignee: Cornell University
    Inventors: John W. Babich, Justin Wilson, Nikki Thiele, James Kelly, Shashikanth Ponnala
  • Patent number: 11276728
    Abstract: A heterostructure includes a substrate exhibiting a piezoelectric effect, and a magnetostrictive film supported by the substrate. The magnetostrictive film includes an iron-gallium alloy. The iron-gallium alloy has a gallium composition greater than 20%.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: March 15, 2022
    Assignees: The Regents of the University of Michigan, Cornell University
    Inventors: John Thomas Heron, Peter Benjamin Meisenheimer, Darrell G. Schlom, Rachel Steinhardt
  • Publication number: 20220075017
    Abstract: Systems and methods are disclosed for optimizing a sub-sampling pattern for efficient capture of a sub-sampled image to be reconstructed to form a high-resolution image, in a data-driven fashion. For example, Magnetic Resonance Imaging (MRI) scans can be accelerated by under-sampling in k-space (i.e., the Fourier domain). Since the reconstruction model's success depends on the sub-sampling pattern, optimization of the sub-sampling pattern can be combined with optimization of the model, for a given sparsity constraint, using an end-to-end learning operation. A machine-learning model may be trained using full-resolution training data that are under-sampled retrospectively, yielding a sub-sampling pattern and reconstruction model that are customized to the type of images represented in the training data.
    Type: Application
    Filed: December 20, 2019
    Publication date: March 10, 2022
    Applicant: Cornell University
    Inventors: Mert R. Sabuncu, Cagla D Bahadir
  • Patent number: 11258405
    Abstract: A device and method for terahertz signal generation are disclosed. Oscillators are arranged in a two-dimensional array, each oscillator connected to a corresponding antenna. Each oscillator is unidirectional connected to its adjacent oscillators by a phase shifter. A method for generating a steerable terahertz signal utilizes an array of oscillators connected by corresponding phase shifters. A terahertz signal having a fundamental frequency is generated using the array. The phase shift of one or more of the phase shifters is varied in order to vary the fundamental frequency and/or steer the signal generated by the array.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: February 22, 2022
    Assignee: Cornell University
    Inventors: Yahya Tousi, Ehsan Afshari
  • Patent number: RE49037
    Abstract: The present invention relates to an exceptionally broad and potent neutralizing antibody which may comprise cross-clade neutralizing coverage of 83% at a median IC50 of 0.003 ?g/ml, compositions containing the same and uses thereof.
    Type: Grant
    Filed: December 24, 2019
    Date of Patent: April 19, 2022
    Assignees: International AIDS Vaccine Initiative, The Scripps Research Institute, Cornell University
    Inventors: Dennis R. Burton, Marit J. Van Gils, Wayne Koff, Pascal R. G. Poignard, Rogier W. Sanders, Melissa D. J. S. Simek-Lemos, Devin Sok