Abstract: Natural language learning in context is provided by generating combined text of a user's native tongue and language to be learned. The combined text is generated based on elements of code-switching including syntax and semantics. Combining text based on elements of code-switching maximizes the learnability or the likelihood of retaining certain text of a foreign language.
Abstract: The present invention relates to compositions comprising terpenes and hollow glucan particles or cell wall particles and methods for preparing such compositions. The compositions increase terpene stability and activity and provide a suitable carrier for the terpenes. The invention also relates to methods of using such compositions in the medical, veterinary and agricultural fields.
Type:
Grant
Filed:
August 3, 2006
Date of Patent:
June 2, 2020
Assignees:
Eden Research PLC, Cornell University
Inventors:
Lanny Franklin, Elizabeth Cloud, Lanna Knapp, Gary Ostroff, Gary Harman
Abstract: This patent document provides optical processing and switching of optical channels based on mode-division multiplexing (MDM) and wavelength division multiplexing (WDM).
Abstract: Tools and techniques for providing joint position error test system are provided. A system includes a head sensing unit coupled to a joint position error processor. The head sensing unit may include a positional sensor and further be configured to be coupled to the head of a test subject. The joint position error processor may include a processor, and non-transitory computer readable media comprising instructions executable by the processor to record reference sensor data from the positional sensor when the test subject's head is in a reference position, record return sensor data when the test subject's head is in a return position. The instructions may further be executable to determine a position error based on the reference sensor data and the return sensor data, and to further determine the presence of a condition of the test subject based on the position error.
Abstract: The present technology provides compounds as well as compositions including such compounds useful in targeted radiotherapy of cancer and/or mammalian tissue overexpressing prostate specific membrane antigen (“PSMA”) where the compounds are represented by the following: or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, wherein M1 is independently at each occurrence an alpha-emitting radionuclide. Equivalents of such compounds are also disclosed.
Type:
Application
Filed:
November 20, 2019
Publication date:
May 21, 2020
Applicant:
Cornell University
Inventors:
John W. Babich, Justin Wilson, Nikki Thiele, James Kelly, Shashikanth Ponnala
Abstract: Described herein is a previously unknown function of XBP1 in triple-negative breast cancer (TNBC). It is shown that XBP1 is preferentially spliced and activated in TNBC, and that deletion of XBP1 significantly blocks triple negative breast tumor growth. Strikingly, XBP1 is required for the self-renewal of breast tumor initiating cells (TICs). Genome-wide mapping of the XBP1 transcriptional regulatory network identified a fundamental role for XBP1 in regulating the response to hypoxia via the transcription factor hypoxia-inducible factor 1? (HIF1?). Importantly, activation of this pathway appears to carry prognostic implications, as expression of the XBP1-dependent signature is associated with shorter survival times in human TNBC.
Abstract: A method is described that includes receiving raw image data corresponding to a series of raw images, and processing the raw image data with an encoder of a processing device to generate encoded data. The encoder is characterized by an input/output transformation that substantially mimics the input/output transformation of at least one retinal cell of a vertebrate retina. The method also includes processing the encoded data to generate dimension reduced encoded data by applying a dimension reduction algorithm to the encoded data. The dimension reduction algorithm is configured to compress an amount of information contained in the encoded data. An apparatus and system usable with such a method is also described.
Abstract: III-Nitride heterostructures with low p-type sheet resistance and III-Nitride heterostructure devices with gate recess and devices including the III-Nitride heterostructures are disclosed.
Type:
Application
Filed:
November 6, 2019
Publication date:
May 7, 2020
Applicant:
Cornell University
Inventors:
Samuel James Bader, Reet Chaudhuri, Huili Grace Xing, Debdeep Jena
Abstract: Systems and methods for detecting deceptive opinion spam. Certain embodiments include a classifier with improved accuracy for detecting deceptive opinion entries. A feature analysis of learned models reveals a relationship between deceptive opinions and imaginative writing. By modeling deception in a generative framework, the prevalence of deception in two popular online review communities may be determined. Deceptive opinion spam is a rapidly growing and widespread problem, especially in review communities with minimal posting requirements.
Type:
Grant
Filed:
October 18, 2012
Date of Patent:
May 5, 2020
Assignee:
Cornell University
Inventors:
Myle Ott, Yejin Choi, Claire Cardie, Jeffrey Hancock
Abstract: A hybrid additive manufacturing approach that incorporates three-dimensional (3D) printing and placement of modules selected from a library of modules to fabricate an electromechanical assembly. By virtue of fabrication of the electromechanical assembly, mechanical properties and electrical properties of the assembly are created. The invention overcomes the material and process limitations of current printable electronics approaches, enabling complete, complex electromechanical assemblies to be fabricated.
Abstract: The present invention relates to the use of cyclic oligosaccharides as chemical complexants of lipofuscin bisretinoids (A2E) to prevent and treat eye (i.e., retinal or macular) disease. Monomeric, dimeric, multimeric, or polymeric oligosaccharide rings act as pharmacologic agents to prevent and treat ophthalmologic disorders triggered by the accumulation of lipofuscin in the retinal pigment epithelium (RPE), which occurs as a consequence of either genetic disorders, such as Stargardt Disease (SD) and Best Disease (BD), or aging, such as Age-Related Macular Degeneration (AMD), or other diseases, such as retinitis pigmentosa, and cone-rod dystrophy.
Abstract: A shape can be 3D printed by advancing a continuous length of material past a cutting head, cutting the material along one or more paths, providing adhesive on a surface of the material, and spirally winding the material onto a spool, such that the cut paths on each layer of the spiral are in alignment according to the 3D printed shape. A 3D printing system includes a material infeed configured to provide a supply of sheet material, a cutting head for cutting the material, a glue applicator, and a gathering spindle configured to rotate such that the material is spirally wound onto the spindle.
Abstract: The disclosure provides compositions comprising peptide-based nanofiber precursors and methods of using the same to inhibit cancerous cell growth and/or to deliver therapeutic or diagnostic agents to cells, e.g., cancerous cells. The compositions of the present technology include peptide-based nanofiber precursors as well as carrier complexes comprising a therapeutic or diagnostic agent, and a peptide-based nanofiber precursor. Also provided herein are methods for delivering a therapeutic or diagnostic agent to a cell comprising contacting the cell with a carrier complex including a therapeutic or diagnostic agent, and a peptide-based nanofiber precursor.
Type:
Application
Filed:
October 18, 2019
Publication date:
April 9, 2020
Applicant:
Cornell University
Inventors:
Shek Hang Benedict LAW, Ching-Hsuan Tung, Vanessa Bellat
Abstract: The present disclosure describes systems and methods to non-invasively determine whether a patient has an autonomic dysfunction. In some implementations, the autonomic dysfunction can be a neurological dysfunction. The system can measure a patient's autonomic nervous system response to a stimulus. The stimulus can be a thermal stimulus, such as a cold temperature. The system can apply the thermal stimulus to an extremity of the patient, such as the patient's hand or arm.
Abstract: A wireless communication apparatus is provided. The wireless communication apparatus includes a denoising circuit configured to receive a noisy complex channel vector(s) in a spatial domain and convert the noisy complex channel vector(s) into a noisy beamspace-domain vector(s) in a beamspace domain. The denoising circuit determines an optimal denoising parameter and denoises the noisy beamspace-domain vector(s) based on the optimal denoising parameter to generate a denoised beamspace-domain vector(s). The denoising circuit then converts the denoised beamspace-domain vector(s) to a denoised complex channel vector(s) in the spatial domain.
Type:
Grant
Filed:
July 2, 2019
Date of Patent:
March 31, 2020
Assignee:
Cornell University
Inventors:
Christoph Emanuel Studer, Ramina Ghods, Seyed Hadi Mirfarshbafan, Alexandra Gallyas Sanhueza
Abstract: Devices and techniques that use nonlinear optical effects in optical fiber to generate optical pulses via nonlinear optical wave mixing for various applications such as coherent Raman microscopic measurements and optical parametric oscillators. In some implementations, a tunable optical delay path is provided to cause an adjustable delay for synchronizing two optical beams of optical pulses.
Abstract: Provided herein are probiotic compositions and methods to enhance bacterial diversity in the intestinal tract of a subject. A probiotic is provided comprising lymphoid tissue-resident commensal bacteria, and optionally IL-10, IL-22, and/or hepcidin. The probiotic can be used to promote intestinal health or to treat or prevent intestinal disease or condition.
Type:
Grant
Filed:
March 14, 2018
Date of Patent:
March 24, 2020
Assignee:
Cornell University
Inventors:
Gregory F. Sonnenberg, Nicholas J. Bessman
Abstract: Electropolymerized polymer or copolymer films on a conducting substrate (e.g., graphene) and methods of making such films. The films may be part of multilayer structures. The films can be formed by anodic or cathodic electropolymerization of monomers. The films and structures (e.g., multilayer structures) can be used in devices such as, for example, electrochromic devices, electrical-energy storage devices, photo-voltaic devices, field-effect transistor devices, electrical devices, electronic devices, energy-generation devices, and microfluidic devices.
Type:
Grant
Filed:
April 3, 2015
Date of Patent:
March 17, 2020
Assignee:
Cornell University
Inventors:
Sean Conte, Gabriel G. Rodriguez-Calero, Cen Tan, Kenneth Hernandez-Burgos, Hector D. Abruna, Nicole Ritzert, Daniel C. Ralph, Wan Li
Abstract: Provided are van der Waals (VDW) films comprising one or more transition metal chalcogenide (TMD) films. Also provided are methods of making VDW films. The methods are based on transfer of monolayer TMD films under vacuum, for example, using a handle layer. Also provided are apparatuses and devices comprising one or more VDW film.
Type:
Application
Filed:
July 10, 2017
Publication date:
March 12, 2020
Applicant:
Cornell University
Inventors:
Jiwoong PARK, Kibum KANG, Hui GAO, Saien XIE, Kan-Heng LEE