Abstract: The present invention relates to substituted methanopyrido [2,1-a]isoindolones of formula I, wherein, R1 is selected from phenylsulfonyl or p-toluenesulfonyl; and n=1, 2, 3; their derivatives, stereoisomers, pharmaceutically acceptable salts and pharmaceutically acceptable compositions having potential muscarinic acetylcholine receptor modulator activity.

Abstract: The present invention disclosed a microcapsule modified with nanomaterial for controlled release of active agent comprising; a core comprising active agent and said polymer shell encompassing said core; characterized in that said polymer shell is made up of polymer nanocomposite and a process for the preparation thereof.

Abstract: A method and system for harvesting molecular structures from non-editable documents is disclosed herein. A non-editable storage document is fed by a feeder which is received by a receiver. The molecular and non-molecular data contained in the non-editable storage document is recognized. The three-dimensional coordinates of the molecular data is separated using a pattern recognition. The molecular coordinates are encoded by a pattern sequence. A bond matrix data of the encoded data is generated. Subsequently the bond matrix data for accuracy is verified by comparing with a stored standardized data into a library.

Abstract: The present invention provides silk fibroin micro-particles having a high crystallinity index (1.3-1.5) and low sphericity index (?0.01) and a process for the preparation thereof. The high crystallinity index confers longer degradation periods to the instant silk fibroin micro-particles, therefore facilitating their use in biomedical applications.

Abstract: The present invention discloses a cobalt compound of formula (I), a process for the preparation and use thereof. The present invention further relates to a pharmaceutical composition and a method inhibition of Tau Aggregation in a subject in need thereof using compound of formula (I).

Abstract: The present invention provides a large scale paintable formulation of bromonapthalimide derivative compounds of formula (I) that shows phosphorescence in liquid state at 25-30° C. as well as their use as an indicator of temperature change in a visually enabled temperature measuring device.

Abstract: The present invention discloses organic flexible ferroelectric polymer nanocomposites. The present invention discloses a composite of fluorinated polymers or their copolymers with halogenated cellulosic materials and a facile process for the conversion of non-electroactive alpha phase of fluorinated polymer to electroactive beta phase of fluorinated polymer. Further, it discloses a device comprising the composite with enhanced dielectric properties.

Abstract: The present invention relates to nimbolide analogs useful as anti-cancer agents and preparation thereof. Particularly the present invention relates to nimbolide analogs of general formula I. wherein, ring M is any ring selected from the group consisting of substituted or unsubstituted aryl, heteroaryl, cycloalkyl and heterocyclic; A and B are selected from the group consisting of C, O, N, S and H; R1, R2, R3, R4, R5 and R6 are selected from the group consisting of C1-C6 alkyl, aryl, heteroaryl, C1-C7 cycloalkyl, heteroalkyl, hydrogen, hydroxy, alkoxy, nitro, halogen, amino, alkylamino, aryl amino and cyano; wherein each of these groups may be further substituted with one or more substituents selected from the group consisting of hydrogen, hydroxy, halogen, cyano, alkyl amino, aryl amino, alkoxy, amino, nitro, aldehyde, carboxylic acid and ester.

Abstract: The present invention relates to a pyridinium oxazole dyad scaffold of formula (I) and a process for the preparation thereof. The present invention further discloses a pyridine compound of formula (II) which is used for the preparation of formula (I) and a process for preparation thereof.

Abstract: Disclosed herein is an expression system for the production and secretion of biologically active clot-specific streptokinase (CSSK) protein in methylotrophic yeast. Yeast-expressed CSSK protein displays improved plasminogen activation and fibrin selectivity. Further disclosed are methylotrophic yeast transformed with at least one copy of functional cDNA sequence encoding CSSK adjunct with modified signal sequence which results in secretion of mature and correctly processed CSSK.

Abstract: The present invention discloses a novel transition metal(s) catalyst supported on nitrogen-doped mesoporous carbon and a process for the preparation of the same. Further, the present invention discloses use of transition metal(s) supported on nitrogen-doped mesoporous carbon catalyst in catalytic transfer hydrogenation reaction. The invention also discloses an improved process for the synthesis of 2,5-Dimethylfuran (DMF) and 2-Methylfuran (MF) from 5-hydroxymethylfurfural (HMF) and furfural respectively, using alcohols as hydrogen donor over a transition metal supported on nitrogen-doped mesoporous carbon, especially ruthenium supported on nitrogen-doped mesoporous carbon without using any co-catalysts.

Abstract: The present invention discloses a cyclic compound of formula (I) and a process of preparation thereof. The present invention further discloses a process for the preparation of compound of formula (II) preferably Hunanamycin A from compound of formula (I).

Abstract: The present invention relates to a photocatalyst composition having visible light activity for hydrogen production through water splitting. More particularly, the present invention discloses a photocatalyst composition comprising a zinc oxide nanoparticles and a conjugated organic moiety selected from the group consisting of oligothiophenes, azo dyes, and perylenes.

Abstract: An improved Mob Control Vehicle (MCV) may be necessary to handle riots and mobs in the streets and grounds at urban and non-urban areas. One of the important requirements of this mob control activity is barricading the entire road or ground in such a way that mob cannot harm the vehicle or ground security personnel directly. Accordingly the present invention provides a Vehicle mounted Sliding Type Retractable mobile Protective Shield, which is integrated with MCV. In general the shield is in fivefold retracted condition on rooftop of the vehicle and can be transported at sites without dismantling. During mob control activities the entire shield is brought down on the ground in vertical position ahead of the vehicle through hydraulically actuated cylinders. The side shield frames are expanded as per requirement or road or ground width, such that it can barricade the entire road or ground to protect the vehicle as well as security personnel from aggressive mob.

Abstract: The invention discloses a process for hydrogenation (alkenes, carbonyl compounds and aromatics) and hydrodeoxygenation (methoxy phenols) of organic molecules using hydrous ruthenium oxide (HRO) and its supported form as a recyclable heterogeneous catalyst in aqueous medium with good yield of desired products (70-100%) under mild reaction conditions.

Abstract: The present invention relates to a compound of general formula (A). The invention provides asynthesis of new 4?-amidotriazole linked podophyllotoxin derivatives of general formulae 8a-z to 9a-z useful as potential anticancer agents against human cancer cell lines and process for the preparation thereof.

Abstract: A biodegradable nano-theranostic composite comprising graphene oxide and lipid in the liposomes in the ration of 0.005 to 0.03 characterized in that the graphene oxide is coated as film on the liposome on the inner side and outer side of the liposome. The composite is capable of safely carrying sensitive cargo without premature release and is fluorescent and absorbs in the NIR region and can perform targeted combined chemo and photothermal therapy. The nanotheranostic nanocomposite is designed to collapse and biodegrade after use.

Abstract: The present invention discloses a novel furo[2,3-b]pyran-2-one compound of formula (I) and a single step process for the preparation of furo[2,3-b]pyran-2-ones using Lewis acid-promoted cascade annulation of alkynols and ?-ketoesters.

Abstract: The present invention provides an efficient process for the isolation of natural crystallized thymol product derived from crude natural Monarda citriodora (Jammu Monarda) oil useful for incorporation into foods and beverages in amounts due to strong antimicrobial, antibacterial, antioxidant properties as well as for use as a preservative. The recovery of crystallized thymol product obtained is more than 72% from Hexane-Jammu Monarda oil in a ratio 1:1 under specific conditions. A method for preparing natural thymol in crystal form involves providing crude Jammu Monarda oil in a Flask and gradually reducing the temperature of the flask containing Monarda oil:Hexane in a step-wise manner, thereby producing highly pure crystals (?95.5%) within 48 h. The methods disclosed herein are suitable for pharmaceutical GMP.

Abstract: The present invention relates to the development of a novel, morphologically and genetically distinct clone of vetiver [Vetiveria zizaniodes (L.) Nash. syn. Chrysopogon zizanioides (L.) Roberty; family Poacaeae] named ‘CIMAP-FORAGIKA’ that offers an ideal plant type to realize the twin application of Vetiver i.e. mitigation of soil erosion and landslides, as well as, a prospective forage in eco-plantations and cropping systems. This clone sports—(i) deep penetrating tufted roots coupled with profuse lateral secondary and tertiary roots that form an interwoven web of roots facilitating enhanced soil binding in landslide and erosion prone sites; and (ii) profuse shoot tillers bearing thinner leaves that have reduced (less) lignified tissue enabling leaf softness and palatability. The leaves of this clone are rich in protein (41 g/kg fresh weight) and crude fiber content (25 g/kg dry weight) but low in carbohydrates (31 g/kg dry weight), thus providing desirable digestibility and nutritional features.