Abstract: Provided is a compound represented by formula (IV) or a salt thereof, wherein the content of the compound represented by formula (I) is 350 ppm by mass or less.

Abstract: Microbolometer detectors and arrays fabricated using printed electronics and photonics techniques, including ink-based printing, are disclosed. A microbolometer detector can include a substrate, a platform suspended above the substrate, and a thermistor printed on the platform and made of a thermistor material including an electrically conducting polymer, for example a poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) polymeric composition. The microbolometer detector can also include an electrode structure electrically connected to the thermistor, and an ohmic contact layer interposed between the thermistor and the electrode structure. The electrode structure can be made of an electrode material including silver, while the ohmic contact layer can be made of an ohmic contact material including a PEDOT-carbon nanotube polymeric composition. A microbolometer array can include a plurality of microbolometer detectors arranged in a linear or two-dimensional matrix.

Abstract: The present invention is directed to methods for treating ebola virus infections or Marburg virus infections comprising administering to a subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof.

Abstract: The invention relates to a method for labeling specifically living microorganisms in a sample comprising microorganisms, the method comprising the steps of: a) incubating said microorganisms of said sample with at least one modified monosaccharide compound comprising a first reactive chemical group capable to chemically react with a second reactive group, so that a residue bearing said first reactive group is incorporated into such microorganisms, and b) contacting said residue incorporated in the microorganisms, with a labeling molecule comprising a said second reactive group, for generating the chemical reaction of said first reactive group of said residue incorporated within said living microorganisms with said second reactive group of said labeling molecule, resulting in a covalent link, characterized in that the said modified monosaccharide compound has the following formula (I?), or a salt thereof: —X can be O, NH or S, preferably O and NH, and —R1 and R2 can be independently H, OH, NH2, OH and NH2 bein

Abstract: The present invention relates to the field of fermentation, more particularly to ethanol production. Even more particularly the present invention relates to reduced aroma production during fermentation processes. The present invention provides mutant alleles and chimeric genes useful to develop yeast strains to limit acetate ester levels during fermentation. In addition, the invention also relates to the use of such yeast strains as well as of compounds for the production of fermented foods and liquids with reduced acetate ester levels.

Abstract: The present disclosure relates to a lithography scanner including: a light source configured to emit extreme ultra-violet (EUV) light; a pellicle including an EUV transmissive membrane that is configured to scatter the EUV light into an elliptical scattering pattern having a first major axis; a reticle configured to reflect the scattered EUV light through the pellicle; and an imaging system configured to project a portion of the reflected light that enters an acceptance cone of the imaging system onto a target wafer, wherein a cross section of the acceptance cone has a second major axis, and wherein the pellicle is arranged such that the first major axis is oriented at an angle relative to the second major axis.

Abstract: The present invention provides antibodies directed against ICOS or a derivative thereof which neutralize ICOS engagement on Treg by inhibiting the fixation between ICOS and ICOS-L and abrogate proliferation of Treg induced by plasmacytoid dendritic cells. The present invention further provides antibodies directed against ICOS or a derivative thereof which induce IL-10 and IFN? production, induce CD4? T cells proliferation, reduce Tconv proliferation, and increase the immunosuppressive function of Treg.

Abstract: Methods for reducing errors in calibrated devices comprise detecting outliers, self-checking consistency of measurements, tuning device controls to target values, and absolutely calibrating devices via a first standard and cross-checking the results via a second standard. The first standard may be a calibrated current and the second calibration standard may be a calibrated frequency. A calibrated frequency may be a microwave signal applied to the body of a qubit. Qubit annealing controls can quickly lower and raise the tunnel barrier to measures the oscillation frequency of the qubit between two potential wells.

Abstract: There is provided a therapeutic agent for Alzheimer's disease and Lewy body dementia for combined use of (S)-7-(2-methoxy-3,5-dimethylpyridin-4-yl)-1-(tetrahydrofuran-3-yl)-1H-pyrazolo[4,3-c]quinoline-4(5H)-one represented by formula (1): or a pharmaceutically acceptable salt thereof, and donepezil represented by formula (II): or a pharmaceutically acceptable salt thereof.

Abstract: A seat for a passenger compartment, for example a vehicle passenger compartment. The seat has a backrest that includes a heating device for heating the space behind the backrest. The heating device includes, from front to back of the backrest, an insulating layer which is a foam, a heating layer, and an outer layer which forms the back of the backrest. The assembly of the insulating layer and the heating layer is achieved by compression on at least their peripheries.

Abstract: The present disclosure relates to 2,6-diaminopurine (DAP) for use in the treatment of a disease caused by a nonsense mutation in a gene, leading to the premature insertion of a UGA stop codon.

Abstract: The present invention relates to a compound having the following formula (I): (I) wherein: —R is a (C1-C6)alkyl group; —R? is preferably H; —Ar is a (C5-C12)arylene radical; —X1 is —C(?O)—or —SO2—; and —R? is chosen from the group consisting of possibly substituted (C1-C6)alkyl, heteroaryl, (C5-C12)aryl, and (hetero)cycloalkyl groups, or a pharmaceutically acceptable salt and/or tautomeric form thereof, or its racemates, diastereomers or enantiomers.

Abstract: An adjustment mechanism for a vehicle seat comprising a transmission housing and a slider comprising a first longitudinal guide member. The slider engaging with the transmission housing by means of the first longitudinal guide member.

Abstract: A spindle drive, a spindle nut for the spindle drive, and a louvre window or louvre shutter having a spindle drive for moving louvre elements. The spindle nut is constructed in multiple parts including a screw nut part, having an internal thread to engage on an external thread of the threaded spindle, and a bearing part in which the screw nut part is mounted. The screw nut part includes a driver structure for transmitting a drive force applied by the threaded spindle to the spindle nut onto an element to be driven. Furthermore, the screw nut part is rotatably mounted in the bearing part in such a way that the screw nut part executes a relative movement in relation to the bearing part, and a directional component of the movement is transverse to a thread longitudinal axis of the internal thread.

Abstract: The present invention relates to a method and an apparatus for coating large area solid substrates such as flakes, powder, beads, and fibres with metal-based coatings by heating the substrate with a powder mixture including reducible metal oxides and a reducing agent. The method is particularly suited for production of substrates coated with metals, alloys and compounds based on Ti, Al, Zn, Sn, In, Sb, Ag, Co, V, Ni, Cr, Mn, Fe, Cu, Pt, Pd, Ta, Zr, Nb, Rh, Ru, Mo, Os, Re and W.

Abstract: Disclosed is a hybrid inertial measurement system including a cold atom interferometric inertial sensor having a laser source generating a sequence of laser pulses towards a cold atom burst and a conventional inertial sensor attached to the inertial reference frame of the interferometric inertial sensor. The hybrid system includes a signal processing system suitable for receiving an inertial measurement signal from the conventional inertial sensor and for generating in real time a non-linear frequency modulation signal, the feedback loop electronic system being configured to modulate in real time the central optical frequency of the laser according to the modulation signal, such that the cold atom interferometric inertial sensor generates a first hybrid inertial measurement signal by atomic interferometry corrected for the relative movements of the inertial reference frame.

Abstract: A device for imaging and delivering spectroscopic information comprises an objective (1), an image sensor (2) and an optical component (3) having a spectral differentiation function. The optical component having a spectral differentiation function modifies the image of a point in different ways for at least two colours, so that a form of the image of the point delivers spectroscopic information that appears directly in the image as captured by the image sensor. Such device may be used in a detection and/or surveillance system, which then possesses a lower probability of false alarm value.

Abstract: A multi-platform vibro-kinetic system comprises a plurality of motion platforms each having actuators to be displaceable to produce vibro-kinetic effects. The system may obtain movements of one or more operator(s), interpret the movements of the operator and identifying from the movements an operator instruction for effect generation, and output a motion signal containing instructions for producing a vibro-kinetic effect on at least one of the motion platforms as a response to the operator instruction.

Abstract: In one aspect, the invention relates to compounds having the formula XII: where Ra, Rb, R2, R7, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds described herein are prodrugs of compounds having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds.