Abstract: Methods for iteratively optimizing a two-dimensioned tiled area such as a lithographic mask include determining a halo area around each tile in the tiled area. An extended tile is made of a tile and a halo area. Each extended tile in the tiled area is iterated until a criterion is satisfied or a maximum number of iterations is met. Optimizing the extended tile produces a pattern for the tile such that at a perimeter of the tile, the pattern matches adjacent patterns that are calculated at perimeters of adjacent tiles.

Abstract: The present invention relates to a specific culture medium for the culture and selective isolation of an Enterococcus hirae bacterium consisting of nutrients other than sugars from a basic culture medium for the culture of enterococci without aesculin, comprising inhibitors of Gram-negative and Gram-positive bacteria other than enterococci and preferably at least one antifungal compound characterized in that it comprises: as inhibitor of Gram-positive bacteria other than enterococci, sodium chloride at a concentration of at least 20 g/L and not more than 60 g/L, and as the only sugar, mannitol, and as the only dye, an indicator dye that changes colour at a pH lower than the pH of said specific culture medium corresponding to the acidification of said specific is culture medium resulting from the consumption of mannitol.

Abstract: The invention relates to an acoustic phase mask, the phase mask having a variation in the acoustic index n, characterized in that the phase mask comprises a body comprising: at least one matrix formed from a deformable solid material, having a shear modulus of less than 10 MPa, and pores formed in the matrix, the pores being mostly filled with gas, the deformable solid material extending between the pores, the body having a porosity ? less than or equal to 50%, and a controlled porosity ? gradient resulting in a variation of the acoustic index n spatially in the body.

Abstract: A carousel for transporting articles includes: a body rotated by a motor around a main axis, a stationary cam around the main axis and a plurality of transfer units mounted on the body to rotate around the main axis. Each unit includes a transfer element having a radially external portion to retain or release an article. The element is pivoted on the body around an auxiliary axis radial to the main axis and is coupled to the body to move along the auxiliary axis. The element is coupled to the stationary cam to rotate around the auxiliary axis. A pair of auxiliary cams is coupled to the element and integral with the body and auxiliary cam-followers are interposed between the element and the auxiliary cam to move on the auxiliary cams during rotation of the element around the auxiliary axis and move the element along the auxiliary axis.

Abstract: Method of manufacturing a photovoltaic device, comprising the steps of: providing a substrate; depositing a first electrode layer on said substrate; depositing a p-type hole transport layer on said first electrode layer; depositing a Perovskite-based absorber layer on said p-type hole transport layer; depositing an n-type electron transport layer on said Perovskite-based absorber layer; and depositing a second electrode layer on said n-type electron transport layer, wherein said second electrode layer comprises boron doped zinc oxide or tin oxide and is deposited by chemical vapour deposition at an absolute pressure of 5 mbar or less.

Abstract: The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.

Abstract: Computer-based systems and methods guide the learning of features in middle layers of a deep neural network. The guidance can be provided by aligning sets of nodes or entire layers in a network being trained with sets of nodes in a reference system. This guidance facilitates the trained network to more efficiently learn features learned by the reference system using fewer parameters and with faster training. The guidance also enables training of a new system with a deeper network, i.e., more layers, which tend to perform better than shallow networks. Also, with fewer parameters, the new network has fewer tendencies to overfit the training data.

Abstract: This method (100) for automatic propagation into an (N+1)-th dimension of an image segmentation initialized in dimension N, N?2, comprises the acquisition (102) of an ordered series of image representations of dimension N and an initial segmentation (104) in dimension N of a region of interest in the first and last image representations of the series, to obtain first and last initial segmentation masks (M0, Mn) of the region of interest. It further comprises an estimation (106) of registration parameters (La, Ld) between the first and last initial segmentation masks, and upward and downward automatic propagations (108) of the initial segmentation, from the first and last image representations, to all the other image representations of the series by step-by-step registration up to the last and first image representations.

Abstract: A retractable tray device for a vehicle, in particular for a motor vehicle, comprising a frame structure, at least one tray, an electric motor fixed to the frame structure, a worm screw rotated by the electric motor, and a slider mounted on the worm screw, the slider being integral with the tray so that the rotation of the worm screw causes a displacement in translation of the slider along the worm screw, and consequently of the tray relative to the frame structure, substantially within the plane of the tray.

Abstract: Operability, accuracy, and safety when fitting a glass-made pipette tip to a pipette are improved. A pipette tip fitting adapter includes a hollow body having one end portion configured to serve as a tip inserting portion into which a pipette tip is inserted, and the other end portion configured to serve as a pipette inserting portion into which a pipette is inserted, and at an opening side of an inner circumferential surface of the tip inserting portion, seal portions projecting inward are formed in a circumferential direction. Accordingly, a pipette tip that is long and heavy like a glass tip can be held.

Abstract: The present invention relates to a dinitroxide biradical compound of general formula (I): In formula (I), A is a carbon, an ammonium, or a phosphonium; each of A1 to A6 is a single bond, O, N, N(O), S, S(O), SO2, C(O), or a (C1-C4) alkyl chain; and Z1 and Z2 are selected from R1 and R2 in combination, so that there is always at least one R2 group that is substituted with R3 group. In Z1 and Z2, R1 is an H, an aryl, or a heteroaryl; R2 is an alkyl chain, an alkenyl chain, an alkynyl chain, a cycloalkyl, a heterocycloalkyl, an aryl, or a heteroaryl; and R3 is an alkyl chain, an alkenyl chain, an alkynyl chain, a cycloalkyl, a heterocycloalkyl, an aryl, a heteroaryl, an ether, an ester, or an azide. When Z1 and Z2 are combined together with the same carbon atom of the nitroxide ring to which they are bonded, they form a spirocycloalkyl or a spiroheterocycloalkyl, the spirocycloalkyl or the spiroheterocycloalkyl being substituted with R3.

Abstract: An aerolysin nanopore or a nanotube is used for the electrical detection of peptides, proteins separated by at least one amino acid and other macromolecules such as polysaccharides or synthetic or natural polymers present in a preparation where said nanopore or nanotube is inserted into a lipid membrane which is subjected to a difference in potential greater than ?160 mV, in a reaction medium having an alkali metal halide electrolyte solution with a concentration of less than 6M and at a temperature of less than 40° C., and where said use is intended to differentiate said peptides, proteins and other molecules according to their length and their mass. Application to the sequencing of peptides and other molecules to differentiate them according to their length and mass with an amino acid-level or monomer-level resolution and to medical diagnosis.

Abstract: A non-transitory machine-readable medium of a computing device storing an application for simulating the loading of an airframe. The application includes an airframe input module that receives an airframe file having a seat having a seat location and a bin having a bin location and a bin dimensions. The application further includes a passenger profile input module that receives a passenger profile file having a list of passenger profiles, a passenger selection module that selects a passenger from the list of passenger profiles and associates the passenger with the seat, a bag selection module that selects a bag profile from a bag profile file and associates it with the passenger, a bag placement module that simulates placing the bag into the bin based on the bin dimensions, bin location, and bag profile, and an output module that outputs and stores a simulation output associating the bag and the bin.

Abstract: Fluid distribution valve (11), particularly for a vehicle screen wash system, characterized in that it comprises a body (41) defining a duct (43) for the passage of fluid and comprising at least one fluid inlet (45) and at least one fluid outlet (47, 49), a membrane (53) housed in the duct and configured to be deformed under the action of a magnetic field between a first position of at least partial closure of the duct and a second position of at least partial opening of the duct, and means (51) for generating a magnetic field within the duct in order to cause the membrane to deform.

Abstract: An implantable microphone for a middle ear prosthesis, includes an attachment system for fixing to a fixation bone close to an individual's middle ear; a cylindrical holding sheath, the sheath to be fixed to the fixation bone by the attachment system and having a suitable shape for extending from the fixation bone towards the ear ossicles of the individual; a coupler including a rod and an end piece of a suitable shape for bringing into contact with a point of the ear ossicles of the individual in a reversible manner; a sensor for converting a mechanical signal into an electrical signal, the sensor being secured to the coupler, supported by the cylindrical holding sheath and placed substantially in the extension of the axis of the cylinder; and a translation system for translation of the coupler along the axis of the cylinder, the translation system being housed in the sheath.

Abstract: A microwave component (10) of the type substrate integrated transmission line, comprises at least one upper layer (14) having at least one electrically conductive surface (26), a lower layer (16) having at least one electrically conductive surface (44), and a central layer (18) defining a propagation area (20) of an electromagnetic wave extending along a propagation axis. The upper layer (14) comprises at least an upper hole (30) passing through it; the lower layer (16) comprises at least one lower hole (46) passing through it. An electrically conductive wire (22) is received through the upper hole (30), the propagation area (20) and the lower hole (46), the conductive wire (22) being electrically connected to the electrically conductive surface (26) of the upper layer (14) and the electrically conductive surface (44) of the lower layer (16).

Abstract: The invention provides compounds of formula (I): wherein X is and the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are useful as JAK kinase inhibitors. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat respiratory diseases, and processes and intermediates useful for preparing such compounds.

Abstract: The invention discloses design of the wideband single, dual or three channel signal detector with ability to suppress interference and crosstalk from two PLL LO signal generators (101 & 102) with selection of best pairs of LO frequencies (108 & 109) out of all possible pairs in the way that all interference is kept out-of-band and with efficient filtering in IF (103) and baseband (104) to achieve high sensitivity for wideband channels without requirement for heavy shielding or adding of absorptive materials to the receiver subsystems. Method for measurement and creating array with frequency pairs to control PLL generators with optimal frequency distribution on each PLL generator for uniform and fastest possible scanning of all required bands is also disclosed.

Abstract: Systems, and method and computer readable media that store instructions for slowing or stopping a progress, towards a target, of a drone controlled by a remote control unit.