Abstract: The present invention relates to the use of polyaminoisoprenyl derivatives in antibiotic or antiseptic treatment of bacteria including those presenting multiple drug resistance (MDR), in particular as efflux pump inhibitors. It also relates to novel polyaminoisoprenyl derivatives, compositions comprising the same, process for preparing the same, and use thereof in antibiotic or antiseptic treatment.

Abstract: An aircraft storage bin that includes an upper housing and a bucket that cooperate to define a bin interior. The bucket is movable with respect to the upper housing between open and closed positions and includes a bottom and right and left side panels. The bottom includes lower and upper surfaces and right and left outer edges. The right and left side panels each include a first section having a first transverse width, a second section having a second transverse width, and a transition section that is located between the first and second sections. The second transverse width is less than the first transverse width. At least a portion of the second section of each of the side panels is received in a slot defined in the upper surface of the bottom of the bucket, such that the right and left side panels extend upwardly from the bottom.

Abstract: An arm support assembly includes an armrest and connecting assembly. The armrest may meet regulatory or industry standards and is maneuverable into a variety of positions, including seated, blood pressure reading, supping or lying, and stowed or patient transfer positions. The armrest may be padded and/or upholstered. The connecting assembly includes first and second joints each selectively rotatable and an elongate member connecting them. The first joint rotatably mounts to the armrest, and the second joint mounts to the side of an examination device such as a table or chair. The joints include a rotary mechanism to engage between locked and unlocked positions, where rotational motion is enabled in unlocked positions. Rotation at first and second joints collectively result in maneuvering the armrest between the various positions.

Abstract: Methods for fracturing or mask data preparation are disclosed in which a set of single-beam charged particle beam shots is input; a calculated image is calculated using a neural network, from the set of single-beam charged particle beam shots; and a set of multi-beam shots is generated based on the calculated image, to convert the set of single-beam charged particle beam shots to the set of multi-beam shots which will produce a surface image on the surface. Methods for training a neural network include inputting a set of single-beam charged particle beam shots; calculating a set of calculated images using the set of single-beam charged particle beam shots; and training the neural network with the set of calculated images.

Abstract: The invention relates to a moisturizing cosmetic composition comprising: (A) 30-99 wt % of birch sap, (B) 0.001-5 wt % of hydrolyzed sodium hyaluronate, and (C) optionally, ingredients commonly used in skincare cosmetics, wherein the moisturizing cosmetic composition of the invention does not comprise water typically added as a separate component.

Abstract: The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of JAK kinases. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat gastrointestinal and other inflammatory diseases, and processes and intermediates useful for preparing such compounds.

Abstract: The invention provides a compound of formula 1 or a pharmaceutically-acceptable salt thereof, that is useful as a JAK inhibitor. The invention also provides crystalline forms of the compound, pharmaceutical compositions comprising the compound, methods of using the compound to treat diseases amenable to a JAK inhibitor, and processes and intermediates useful for preparing the compound.

Abstract: Disclosed is a personal care composition comprising (a) particle comprising chitosan salt at the outer surface of the particle; and (b) functionalized non-volatile silicone, wherein the amount of the functionalized non-volatile silicone is greater than 20% by weight of the total non-volatile silicone.

Abstract: A complete backyard control solution accessible from anywhere in the world via the Internet or other network. Control and set schedules for a multitude of relays, varying voltages control 12, 24, 110 and 220 volt devices from the palm of your hand. Webpage access does not require any special apps. Open your web browser, login to your account and have access to any and all of your available features. Install a wide array of sensors and set programming options to depend on the values of the sensors. Install a remote sensor and never have to worry about manual missteps.

Abstract: Apparatus and methods for analyzing a bodily sample are described. A microscope system acquires one or more microscope images of the bodily sample. A computer processor identifies, in the one or more images, at least one element as being a candidate of a given entity. The computer processor extracts, from the one or more images, at least one candidate-informative feature associated with the candidate of the given entity, and at least one sample-informative feature that is indicative of a characteristic of the bodily sample as a whole. The computer processor processes the candidate-informative feature in combination with the sample-informative feature, and generates an output upon the output device, in response thereto. Other applications are also described.

Abstract: Compounds of formula (I) are A2B receptor antagonists: Wherein R1 is optionally substituted aryl or an optionally substituted 5- or 6-membered heteroaryl ring; R2 and R3 are independently selected from hydrogen, C1-C6 alkyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-(C1-C6)-alkyl, aryl-(C1-C6)-alkyl optionally substituted in the ring part thereof, a 5- or 6-membered monocyclic heterocyclic group optionally linked via a C1-C6 alkylene chain and optionally substituted in the ring part thereof, benzimidazol-2-yl-methyl, pyrid-3-yl-carbonyl, or (1-methyl-piperidin-4-yl)-carbonyl-methyl; or R2 and R3 taken together with the nitrogen atom to which they are attached form an optionally substituted 5- or 6-membered ring; R4 is C1-C3 alkyl, C2-C3 alkenyl, —N(—R5)—R6, or optionally substituted heteroarylmethylamino; and R5 and R6 are independently selected from hydrogen or C1-C3 alkyl; or R5 and R6 taken together with the nitrogen atom to which they are attached form an optionally substituted 4- to 6-membered saturated rin

Abstract: A rigid pack for tobacco articles having: at least one wrap of parallelepiped shape, which encloses a group of tobacco articles; a rigid container whose inner volume is divided into a top chamber, which houses the wrap and a bottom chamber which is available; a rigid lid hinged to the container; a rigid collar, which is folded in a “U”-shape, and is arranged inside the container; a drawer, which is arranged in the area of the bottom chamber, is cup-shaped and has a sliding opening by means of linear movement between a closed position in which the drawer is completely arranged inside the container and an open position in which the drawer is partially pulled out of the container and projects outwards from the container; and a limit stop device, which fulfils the function of stopping the outward movement of the drawer from the container in a maximum open position, namely of preventing the drawer from being completely pulled out of the container by setting a maximum limit for the pull-out movement of the drawer f

Abstract: A transponder communicates with a reader using active load modulation. The transponder includes a digital phase locked loop (DPLL), which, in operation, generates an active load modulation (ALM) carrier clock synchronized to carrier clock of the reader. Between transmission of data frames, the DPLL is placed in a lock mode of operation in which a feedback loop of the DPLL is closed. Within a transmitted data frame having a duration, the DPLL is placed, for the duration of the transmitted data frame, in a hold mode of operation in which the feedback loop is opened. A phase of the ALM carrier clock is adjusted at least once during the duration of the transmitted data frame.

Abstract: Systems and methods for conducting an electronic assessment in an electronic learning (eLearning) environment are provided. The system includes a display and at least one processor operatively coupled to the display. The at least one processor configured for: providing an electronic assessment comprising a plurality of assessment tasks for a current participant to complete within an allocated amount of assessment time; determining context-dependent time requirement (CDTR) value for at least one of the assessment tasks based upon historical performance data associated with that task, the CDTR value being indicative of a suggested amount of time required to complete that task; and providing the CDTR value to the current participant.

Abstract: A heat recovery device extends between an inlet and an outlet for exhaust gas, and includes a valve delimiting a direct passage for gas between the inlet and the outlet. The valve comprises a valve body housing a gate movable between a closing off position and a released position. A heat exchanger has an exchanger inlet upstream of the gate and an exchanger outlet downstream of the gate. The valve comprises a tube partially extending inside the valve body up to a mouth edge at a distal end, with the mouth edge extending in a plane. The gate has a plane contact surface configured to come in a direct contact with the mouth edge when the gate is in the closing off position.

Abstract: A piston and cylinder type damper is provided, with a cylinder (11) having a piston assembly (15) mounted for reciprocal movement therein. The piston assembly (15) divides the cylinder (11) into two separate chambers (12a, 12b), with a restricted flow path (30, 31) for passage therebetween of damping fluid contained within the cylinder. A piston rod (13) is mounted for reciprocal movement with respect to the cylinder (11) and acts via a first one of the chambers (12a) on the piston assembly (15) in a first direction. A seal assembly (17) is provided for sealing between the piston rod (13) and the cylinder (11) in order to retain damping fluid in the first chamber (12a). The seal assembly (17) is movable axially with respect to the cylinder (11), with the cylinder further including a centering device (24) for assisting alignment of the seal assembly (17).

Abstract: A Laser system is disclosed which comprises a pump, wherein the laser system is adapted to be operated in pulsed operation so that at least one individual pulse of a temporally limited pulse duration (T0) is generated, wherein the pulse ablates a material such that a debris cloud forms above the ablated material. Further, the pump power of the pump is modulated in such a way that the following three conditions are fulfilled: (1) the intensity of the pulse oscillates between maximum values and minimum values during the pulse duration, wherein the laser pulse comprises a plurality of intensity maxima Imax which occur at times {Ti, i=1, . . . N}; and a plurality of intensity minima Imin which occur at times {tk, k=1, . . .

Abstract: The invention relates to an AC power adapter plate capable of being mounted to a wall, ceiling, or power receptacle which comprises ports for connecting and providing DC power to peripheral devices and accessories.