Patents Assigned to D
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Patent number: 9727946Abstract: A method for customizing an electronic image display device having at least one display parameter of variable value includes: a) linking the electronic image display device to a user database, determining and recording at least one value of an evaluation parameter for the visual and oculomotor profile of a user; b) linking the electronic image display device to a display database and making a digital record including a plurality of values for the display parameter which are associated with an electronic image display device; c) selecting an optimum value for the display parameter from among the plurality of display parameters values in the digital record that are associated with the electronic image display device in the display database according to the visual acuity measurement associated with this user in the user database; d) automatically applying the optimum value for this image display parameter to the electronic image display device.Type: GrantFiled: March 25, 2014Date of Patent: August 8, 2017Assignee: ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE)Inventor: Anne-Catherine Scherlen
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Patent number: 9725448Abstract: In one aspect, the invention relates to compounds having the formula: where R1, R2a, R2b, R3-R6, a, b, Z, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.Type: GrantFiled: September 20, 2016Date of Patent: August 8, 2017Assignee: Theravance Biopharma R&D IP, LLCInventors: Melissa Fleury, Roland Gendron, Adam D. Hughes, Cameron Smith
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Publication number: 20170217112Abstract: A method for dyeing a transparent article made of a polymeric substrate with gradient tint comprising: a) a first step of photodegrading the polymeric substrate (1) of the transparent article, by irradiation (3) of at least one first surface of the article to UV radiations to produce a gradiently photodegraded surface layer of the polymeric substrate, and b) a second step of dyeing said first face of the article with a dyeing agent so as to diffuse said dyeing agent into the gradiently photodegraded surface layer of the polymeric substrate.Type: ApplicationFiled: July 30, 2014Publication date: August 3, 2017Applicant: Essilor International (Compagnie Generale D'Optique)Inventor: Sunil Madhukar BHANGALE
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Publication number: 20170216272Abstract: Provided herein are methods and compositions for modulating the activity or level of a sirtuin, thereby treating or preventing obesity or an insulin resistance disorder, such as diabetes in a subject. Exemplary methods comprise contacting a cell with a sirtuin activating compound or an inhibitory compound to thereby increase or decrease fat accumulation, respectively.Type: ApplicationFiled: February 3, 2017Publication date: August 3, 2017Applicants: President and Fellows of Harvard College, The General Hospital Corporation d/b/a Massachusetts General HospitalInventors: David A. Sinclair, Maria Alexander-Bridges
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Publication number: 20170216130Abstract: A exercise roller device including a center roller portion provided with shaped end roller portions, and the center roller portion provided with a centered circumferential groove. A method of making the exercise roller device.Type: ApplicationFiled: April 19, 2017Publication date: August 3, 2017Applicant: COULTER VENTURES LLC d/b/a ROGUE FITNESSInventor: Dylan JONES
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Publication number: 20170216114Abstract: The embodiment described and claimed herein are improved barrier-type wheelchair securement systems. In particular, one embodiment of a barrier includes an integral shoulder belt assembly, two integral wheelchair restraint assemblies, and two integral lap belt assemblies. The wheelchair restraint and lap belt assemblies comprise retractors which can be mounted external or internal to the barrier. The integral shoulder belt assembly could be connected to a vertical telescoping member which is movable from a first position, wherein the telescoping member is housed inside of the barrier, to a second position, wherein the shoulder belt assembly is disposed at a proper height for a wheelchair passenger. Alternatively, the shoulder belt assembly could be rigidly mounted to the barrier in a fixed position, or could be adjustable to accommodate passengers of varying size.Type: ApplicationFiled: April 10, 2017Publication date: August 3, 2017Applicant: VALEDA COMPANY LLC (d/b/a "Q'Straint")Inventors: Jean-Marc Girardin, Eric Girardin, Joe Esteireiro
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Publication number: 20170223796Abstract: A driving apparatus configured to drive a light emitting device includes a driving current source module operable to supply current to the light emitting device via a node during operation. A protection module coupled to the node and the driving current source module selectively injects current to the node during operation. The driving current source module is controlled based on a detection result of a voltage on the node.Type: ApplicationFiled: April 13, 2017Publication date: August 3, 2017Applicant: STMicroelectronics (Shenzhen) R&D Co. LtdInventors: Yi Jun Duan, Tao Tao Huang
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Publication number: 20170215746Abstract: An automated assessment of a patient's peripheral vascular condition includes using a pulse oximeter to generate at least a perfusion index relative to a limb or digit of the patient. Pressure is applied to the limb or digit, and while increasing or decreasing the pressure, a change in the perfusion index is determined. The change is indicative of a cessation of blood flow or a return of blood flow in the limb or digit. A systolic blood pressure is thereafter determined based on the pressure applied at the time of cessation of blood flow or the return of blood flow in the limb or digit. Using a pulse oximeter to generate a perfusion index may include transmitting light into the limb or digit, detecting light that was transmitted into tissue in the limb or digit, and calculating the perfusion index based on the light transmitted through the tissue.Type: ApplicationFiled: April 19, 2017Publication date: August 3, 2017Applicant: D. E. Hokanson, Inc.Inventors: Donald I. Masin, Molly Ciliberti, Kyra M. Gray
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Publication number: 20170217837Abstract: A process for producing a refractory material for use in the superstructure of glass melting tanks contains, as main components, SiO2, SiC and a binder or binder mixture. A particulate substance, which in the spectral range from 1 ?m to 5 ?m and at temperatures above 1000° C. has a spectral emission capability which is higher than the spectral emission capability of the matrix of the refractory material, is incorporated into the matrix of the refractory material. A method of increasing the spectral emissivity of shaped, fired, refractory materials, is also provided.Type: ApplicationFiled: July 29, 2015Publication date: August 3, 2017Applicant: P-D REFRACTORIES GMBHInventor: FRED BRUNK
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Publication number: 20170219175Abstract: A lighting apparatus to be installed in an area adjacent to land is provided. The lighting apparatus includes a plurality of light sources disposed on a board and further includes a light shield. The light shield blocks a portion of light emitted from the light sources. The portion of light has a predetermined wavelength. The light shield is disposed on the board closer to the land than at least a light source disposed closest to the land among the light sources. The light shield has a shape which sends, to the land, first emission light included in the light emitted from the light sources. The shape avoids sending, to the land, second emission light included in the light emitted from the light sources. The first emission light passes through the light shield. The second emission light does not pass through the light shield.Type: ApplicationFiled: January 30, 2017Publication date: August 3, 2017Applicant: PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LT D.Inventors: Tohru HIMENO, Makoto YAMADA, Shinichi AOKI, Hideki WADA
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Publication number: 20170217959Abstract: In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.Type: ApplicationFiled: December 14, 2016Publication date: August 3, 2017Applicant: THERAVANCE BIOPHARMA R&D IP, LLCInventors: Cameron Smith, Ryan Hudson, Adam D. Hughes
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Publication number: 20170217955Abstract: The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, wherein U, J, V, X, R1a, R2b, R2c, R5 and t are as described herein. The present invention relates generally to inhibitors of histone deacetylase and to methods of making and using them. These compounds are useful for promoting cognitive function and enhancing learning and memory formation. In addition, these compounds are useful for treating, alleviating, and/or preventing various conditions, including for example, neurological disorders, memory and cognitive function disorders/impairments, extinction learning disorders, fungal diseases and infections, inflammatory diseases, hematological diseases, and neoplastic diseases in humans and animals.Type: ApplicationFiled: May 5, 2016Publication date: August 3, 2017Applicants: The Broad Institute, Inc., The General Hospital Corporation d/b/a Massachusetts General Hospital, Massachusetts Institute of TechnologyInventors: Edward Holson, Florence Fevrier Wagner, Michel Weiwer, Li-Huei Tsai, Stephen J. Haggarty, Yan-Ling Zhang
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Patent number: 9719250Abstract: A method and a system for fastening an object to a façade comprising at least one supporting wall made in a hard material coated externally with a thermal insulation coat made in a crumbly material, the object being fastened to the wall by means of a fastening member received in an area for receiving a plot made in a hard material arranged in projection out of the wall. The object is fastened to the wall in an indirect way offsetting towards the outside of the façade the area of the plot. The plot is fastened to the wall by a fastening area extending between the wall and the receiving area. The plot is a straight cylinder extending through the insulation coat.Type: GrantFiled: July 20, 2012Date of Patent: August 1, 2017Assignee: SOCIETE DE PROSPECTION ET D'INVENTIONS TECHNIQUES—SPITInventors: Matthieu Perrier, Alain Gauthier
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Patent number: 9720262Abstract: A method of processing an order request for an ophthalmic lens to be manufactured by a manufacturing device includes the following steps: receiving an order request including at least information related to an ophthalmic wearer's prescription by a first processing device; processing the order request by the first processing device on the basis of predetermined processing rules so as to obtain manufacturing parameters to be applied to the manufacturing device so as to manufacture the ophthalmic lens according to the information included in the order request; sending and storing the manufacturing parameters identified as requiring a further modification to a storing device and sending the other manufacturing parameters to the manufacturing device; modifying the stored manufacturing parameters by a second processing device and sending the modified manufacturing parameters to the manufacturing device.Type: GrantFiled: December 14, 2012Date of Patent: August 1, 2017Assignee: ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE)Inventors: Laurent Marcepoil, Jerome Concialdi, Frederic Dubois
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Patent number: 9717441Abstract: An automatic process of predictive determination of the position and movements of the skin of a subject in a zone of interest, with the subject breathing freely or in an assisted manner, includes preliminarily acquiring multiple configurations of the skin profile in axial planes, at given successive times, in different respiratory positions, and for each axial plane, constructing at least one deformable digital model starting from different skin profiles, then noting, in a repetitive manner, the actual position of a point on the skin at the level of each axial plane, whose position is significantly modified during inhalation and exhalation phases, and providing, essentially in real time, a simulation of the skin profile in each axial plane, as a function of the actual position noted, and an evolving three-dimensional representation of the skin at the level of the zone of interest, by interpolation between the different axial planes.Type: GrantFiled: March 3, 2014Date of Patent: August 1, 2017Assignee: INSTITUT DE RECHERCHE SUR LES CANCERS DE L'APPAREIL DIGESTIF—IRCAD (ASSOCIATION REGIE PAR LES ARTICLES 21 A 79 DU CODE CIVIL ET LOCAL ET INSCRITE AU REGISTRE DES ASSOCIATIONS DU TRIBUNAL D'INSTANCE DE STRASBOURG)Inventors: Luc Soler, Jacques Marescaux, Stephane Nicolau, Alexandre Hostettler
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Patent number: 9720261Abstract: Disclosed is a method for manufacturing an ophthalmic lens including a substrate and a functional film securely fastened to a curved face of the substrate. This method includes a method for gluing the initially flat functional film to the curved face. To ensure that the functional film when securely fastened to the curved face filters a preset band of wavelengths centered on a wavelength denoted ?p, multiple functional films are preselected; two knowledge bases are established experimentally; a film is selected, using the two knowledge bases, from the plurality of preselected films, the wavelength ?i? on which is centered the band of wavelengths that this film filters for a certain degree of deformation being equal to ?p when the degree of deformation is that given for the curvature in question; and the gluing method is implemented in order to securely fasten the selected film to the curved face.Type: GrantFiled: May 20, 2015Date of Patent: August 1, 2017Assignee: ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE)Inventor: Christelle Marck
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Patent number: 9718793Abstract: Isoxazoles of formula (A) or (B) are inhibitors of HSP90 activity, and useful for treatment of, for example cancers: wherein R1, is a group of formula (IA): —Ar1-(Alk1)p-(Z)r-(Alk2)s-Q, wherein in any compatible combination Ar1 is an optionally substituted aryl or heteroaryl radical, Alk1 and Alk2 are optionally substituted divalent C1-C6 alkylene or C2-C6 alkenylene radicals, p, r and s are independently 0 or 1, Z is —O—, —S—, —(C?O)—, —(C?S)—, —SO.sub.Type: GrantFiled: June 27, 2013Date of Patent: August 1, 2017Assignees: Vernalis (R&D) Ltd., Cancer Research Technology Limited, The Institute of Cancer ResearchInventors: Martin James Drysdale, Brian William Dymock, Harry Finch, Paul Webb, Edward McDonald, Karen Elizabeth James, Kwai Ming Cheung, Thomas Peter Matthews
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Patent number: 9719987Abstract: The present invention relates to methods for determining the probability of transplant rejection based on the determination in the subject recipient of the transplant of the levels of antibodies specific for hyaluronic acid. The invention relates as well to methods for attenuating transplant rejection and compositions to prevent transplant rejection based on the depletion of anti-hyaluronic acid antibodies from the subject.Type: GrantFiled: August 12, 2013Date of Patent: August 1, 2017Assignee: FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE (IDIBELL)Inventor: Rafael Mañez Mendiluce
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Patent number: D793229Type: GrantFiled: March 11, 2016Date of Patent: August 1, 2017Assignee: Visy R & D Pty LtdInventor: Sean Meneaud
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Patent number: D794215Type: GrantFiled: December 1, 2015Date of Patent: August 8, 2017Assignee: M-D Building Products, Inc.Inventors: Robert Reed Reutlinger, Kipp Collins, Howard McClure