Patents Assigned to DEVELOPMENT FOUNDATION
  • Publication number: 20140223610
    Abstract: The present invention relates to bio-engineered photosystems, specifically photosystem II (PSII) having an alternative electron transfer pathway that enables electron flow from PSII to a water-soluble protein electron carrier. The present invention further relates to methods and systems for electron transfer using the bio-engineered photosystems. Such photosystems may be utilized for electrical energy production, hydrogen production and/or reduction of carbon-based gases (for example, CO2 and CO) to liquid fuels.
    Type: Application
    Filed: April 18, 2014
    Publication date: August 7, 2014
    Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION, LTD.
    Inventors: Noam ADIR, Gadi SCHUSTER, Shirley LAROM, Faris SALAMA
  • Publication number: 20140219666
    Abstract: A receiver and a multi-symbol-differential-detection (MSDD) module, the MSDD may include an input node for receiving an input signal having a noisy phase; a summation and rotation unit; and an output unit; wherein the output unit is arranged to output an output signal and a normalized output signal; wherein the output signal represents the input signal but has a reconstructed phase; wherein the summation and rotation unit is arranged to receive the input signal and the output signal and to provide a reference signal that reflects a weighted sum of phase rotated and delayed previously received input signals; wherein the output unit comprises a phase difference calculator, a slicer, a delay unit and a normalizer; wherein the phase difference calculator is arranged to generate a difference signal indicative of a phase difference between the reference signal and the input signal; wherein the slicer and the delay unit are arranged to generate the output signal by slicing the difference signal to provide a sliced s
    Type: Application
    Filed: March 1, 2012
    Publication date: August 7, 2014
    Applicant: Technion Research and Development Foundation LTD.
    Inventors: Igor Tselniker, Netta Sigron, Moshe Nazarathy
  • Publication number: 20140214736
    Abstract: A method training a randomized decision tree through multiple iterations, each is based on: a) Receiving multiple data samples that include data subsets, each data subset corresponds to an attribute. b) Distributing the data subsets to slave processing units after sorting the data samples in consecutive ascending order by updating a first index that identifies trajectories of the training data samples through the tree nodes of the previous tree level. c) Simultaneously processing the data subsets to identify split functions for each tree node with respect to each data subset and updating a second index that identifies the trajectories of the training data samples through the tree node of the current tree level. d) Collecting the split functions from the slave processing units and constructing the current tree level by selecting a preferred split function for each tree node of the current tree level.
    Type: Application
    Filed: January 30, 2014
    Publication date: July 31, 2014
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Ron KIMMEL, Aaron Wetzler
  • Patent number: 8791064
    Abstract: The present invention provides colloidally stable dispersions of nanoparticles comprising beta-lactoglobulin and a polysaccharide which are transparent when diluted in aqueous media. In particular these colloidally stable dispersions of nanoparticles are useful as delivery vehicles of hydrophobic nutraceuticals and fat-soluble vitamins, for enrichment of food products, especially of transparent beverages and other non-fat or low fat foods and drinks. The present invention further provides methods for the preparation of said colloidally stable dispersions.
    Type: Grant
    Filed: April 26, 2009
    Date of Patent: July 29, 2014
    Assignee: Technion Research and Development Foundation Ltd.
    Inventor: Yoav D. Livney
  • Patent number: 8790246
    Abstract: A self-propelled device for locomotion through a lumen, comprising a set of serially arranged inflatable chambers, and incorporating a number of novel aspects. To enable easy insertion and use, the rigidity of the device is increased by means of rigid inserts in the balloons, or by use of stiff springs between segments. The working channel can be attached to the distal chamber of the device, such that it is pulled from the leading end of the device during inflation, rather than being pulled from the trailing end of the device during deflation. Lumen wall inspection or treatment facilities are enabled by means of a camera or treatment arm mounted between two distally positioned balloons, the device is able to provide observation capabilities to the lumen wall, yet without becoming excessively dirty by exposure to the front end of the device, as in prior art camera units.
    Type: Grant
    Filed: April 28, 2013
    Date of Patent: July 29, 2014
    Assignee: Technion Research And Development Foundation Ltd.
    Inventors: Noam Hassidov, Daniel Glozman, Moshe Shoham
  • Patent number: 8790270
    Abstract: A method of monitoring lung ventilation of a subject is disclosed. The method comprises recording signals from a plurality of sensing location on the chest of the subject, at least a portion of the signals being indicative of a local motion of the chest at a respective sensing location. The method further comprises operating a data processing system to analyze the signals such as to determine a status of the ventilation, thereby to monitor the lung ventilation of the subject.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: July 29, 2014
    Assignee: Technion Research & Development Foundation Ltd.
    Inventors: Amir Landesberg, Dan Waisman, Carmit Levy
  • Patent number: 8791099
    Abstract: Transition metal complexes of amphiphilic/bipolar corroles, optically active isomers or pharmaceutically acceptable salts thereof are useful for prevention of a cardiovascular disease or disorder in a subject susceptible to develop such a cardiovascular disease or disorder.
    Type: Grant
    Filed: August 4, 2008
    Date of Patent: July 29, 2014
    Assignee: Technion Research and Development Foundation Ltd.
    Inventors: Zeev Gross, Michael Aviram, Adi Haber, Bianca Fuhrman, Atif Mahammed, Raymond Coleman
  • Patent number: 8789795
    Abstract: A propulsion system and method are described configured to exert a force upon a vehicle. The system includes a concentrated mass which may be discharged from the vehicle by a propellant typically via an ejection tube. The system is optimized so that the discharged concentrated-mass imparts a large impulse upon the vehicle. The system and method may be used to alter the momentum of vehicles for propulsion, attitude correction, vehicle separation and the like.
    Type: Grant
    Filed: March 3, 2010
    Date of Patent: July 29, 2014
    Assignee: Technion Research and Development Foundation Ltd.
    Inventors: Alon Gany, Dan Michales
  • Patent number: 8790963
    Abstract: A light emitting diode array includes a first light emitting diode having a first electrode and a second light emitting diode having a second electrode. The first and second light emitting diodes are separated. A first polymer layer is positioned between the light emitting diodes. An interconnect located at least partially on the first polymer layer connects the first electrode to the second electrode. A permanent substrate is coupled to the light emitting diodes. The permanent substrate is coupled to the side of the light emitting diodes opposite the interconnect. A second polymer layer at least partially encapsulates the side of the light emitting diodes with the interconnect.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: July 29, 2014
    Assignees: Phostek, Inc., NCKU Research and Development Foundation
    Inventors: Ray-Hua Horng, Heng Liu, Yi-An Lu
  • Publication number: 20140206448
    Abstract: A method for restricting the number of consequential interactions to further virtual objects having a relationship with a first virtual object, resulting from an interaction with said first virtual object. The method comprises: defining a maximum number of consequential interactions, counting consequential interactions, and stopping further interaction when the maximum number of consequential interactions is reached.
    Type: Application
    Filed: March 24, 2014
    Publication date: July 24, 2014
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Gershon Elber, Orit Shaked, Oded Shmueli
  • Patent number: 8785385
    Abstract: Disclosed are variant RTEF-1 polypeptides having an RTEF-1 amino acid sequence with one or more internal deletions, wherein the polypeptides reduce VEGF promoter activity. Some of the RTEF-1 polypeptides include an amino acid sequence that is at least 80% identical to the contiguous amino acids of 1) amino acids 24 to 47 of SEQ ID NO:15 and 2) each of SEQ ID NOs:16 and 17, but does not comprise the contiguous amino acids of SEQ ID NOs:8, 9, 11, or 12. Also disclosed are nucleic acids encoding the variant RTEF-1 polypeptides of the present invention. Pharmaceutical compositions that include the polypeptides and nucleic acids of the present invention are also disclosed. Methods of inducing cell contact inhibition, regulating organ size, and reducing intracellular YAP activity are also set forth, as well as methods of treating hyperproliferative diseases such as cancer using the pharmaceutical compositions of the present invention.
    Type: Grant
    Filed: April 19, 2011
    Date of Patent: July 22, 2014
    Assignees: Research Development Foundation, Oregon Health & Science University
    Inventors: J. Timothy Stout, Binoy Appukuttan, Trevor McFarland, Anna Dye
  • Patent number: 8784685
    Abstract: The invention relates to a core-alloyed shell semiconductor nanocrystal comprising: (i) a core of a semiconductor material having a selected band gap energy; (ii) a core-overcoating shell consisting of one or more layers comprised of an alloy of the said semiconductor of (i) and a second semiconductor; (iii) and an outer organic ligand layer, provided that the core semiconductor material is not HgTe. In certain embodiments, the core semiconductor material is PbSe and the alloy shell semiconductor material has the PbSexS1-x structure; or the core semiconductor material is CdTe and the alloy shell semiconductor material has either the CdTexSe1-x or CdTexS1-x structure.
    Type: Grant
    Filed: May 14, 2010
    Date of Patent: July 22, 2014
    Assignee: Technion Research and Development Foundation Ltd.
    Inventors: Efrat Lifshitz, Ariel Kigel, Maya Brumer-Gilary, Aldona Sashchiuk, Lilac Amirav, Viktoria Kloper, Dima Cheskis, Ruth Osovsky
  • Publication number: 20140200204
    Abstract: Embodiments of the invention relate to methods of treatment a cardiovascular disease in a patient comprising administering an effective amount of a statin or a pharmaceutically acceptable salt thereof in combination with an effective amount of a transition metal complex of a corrole, an optically active isomer thereof or a pharmaceutically acceptable salt thereof. Further embodiments refer to pharmaceutical compositions comprising a statin and a corrole.
    Type: Application
    Filed: August 14, 2012
    Publication date: July 17, 2014
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Zeev Gross, Michael Aviram, Adi Haber
  • Publication number: 20140199237
    Abstract: The present invention relates to antibodies against specific domains of Olfml3 and the use of such in angiogenesis. In particular aspects, angiogenesis-related conditions, such as cancer, can be treated by the composition comprising the Olfml3 antagonists.
    Type: Application
    Filed: January 17, 2014
    Publication date: July 17, 2014
    Applicant: RESEARCH DEVELOPMENT FOUNDATION
    Inventors: Beat A. IMHOF, Marijana MILJKOVIC-LICINA, Philipe HAMMEL
  • Patent number: 8779543
    Abstract: A semiconductor device that may include an avalanche photodiode (APD), the APD may include: a first doped region of a first polarity; a buried guard ring of a second polarity, the second polarity is opposite to the first polarity, the buried guard ring is spaced apart from the first doped region and is positioned below the first doped region; a well of the second polarity, wherein the well interfaces the first doped region to form a p-n junction; and a second doped region of the second polarity, the second doped region is spaced apart from the first doped region.
    Type: Grant
    Filed: September 16, 2012
    Date of Patent: July 15, 2014
    Assignee: Technion Research and Development Foundation Ltd.
    Inventors: Yael Nemirovsky, Vitali Savuskan, Sharon Bar-Lev Shefi, Igor Brouk, Gil Visokolov, Amos Fenigstein, Tomer Leitner
  • Patent number: 8780176
    Abstract: A system and a method for acquiring an image of a particle flowing in a vessel, the system comprising a light source for generating an illuminating light, an imaging probe for laterally statically illuminating at least a portion of said vessel with the illuminating light, a detection unit for detecting emitted light from an illuminated portion of said particle, and a processor unit for reproducing an image of the illuminated portion of said particle from the emitted light.
    Type: Grant
    Filed: August 17, 2009
    Date of Patent: July 15, 2014
    Assignee: Technion Research & Development Foundation Limited
    Inventor: Dvir Yelin
  • Patent number: 8765467
    Abstract: Methods are provided for producing novel multicellular compositions comprising cancer cells together with pluripotent human stem cells, which are capable of proliferating and differentiating into various normal cell lines and tissue structures. These novel multicellular compositions are useful for investigating the properties of cancer cells in a normal human tissue microenvironment, and for studying interventions that will modulate these properties including devising, testing and screening therapeutic drugs.
    Type: Grant
    Filed: May 5, 2004
    Date of Patent: July 1, 2014
    Assignee: Technion Research and Development Foundation Ltd.
    Inventors: Karl L. Skorecki, Maty Tzukerman
  • Patent number: 8766634
    Abstract: A device of estimating a dose of ionizing radiation absorbed in an intra bone volume. The device comprises a static magnetic field source adapted to generate a substantially static magnetic field in a probing space having a volume of less than 2 cubic millimeter (mm3), the probing space being placed in front of a distal end of static magnetic field source, a micro resonator mounted in adjacent to the distal end, and at least one transmission line which feeds the resonator so as to generate an microwave magnetic field at the probing space and to transmit a signal returned from said microwave magnetic field and indicative of radiation induced paramagnetic defects in said probing space so as to allow a spectrometer to compute a dose of ionizing radiation absorbed in a portion of a bone placed in the probing space according to an analysis of the signal. The static magnetic field source being sized and shaped to maneuver the probing space to overlap with an intra bone volume of the bone.
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: July 1, 2014
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Aharon Blank, Ygal Twig
  • Patent number: 8764403
    Abstract: The present invention relates to enhancing performance of fans and propellers using outsized Gurney flaps. Specifically, the current invention proposes the application of ‘outsized Gurney flaps’ (OGFs) to the trailing-edges of fan blades. According to an exemplary embodiment of the current invention, the Gurney flaps are larger than 10% of the fan blade chord length. Attaching OGFs is not only non-obvious; it seems counterintuitive, because it is akin to placing a large bluff body onto a flow. Preliminary experimental data acquired at Reynolds numbers typically exist during fan operation on idealized blade profiles showed a 100% increase in the generated lift and 40% to 60% increase in aerodynamic efficiency. This translates to significant improvements in fan performance at a given rpm, and/or significant saving in power and noise reduction for the same aerodynamic performance.
    Type: Grant
    Filed: January 1, 2009
    Date of Patent: July 1, 2014
    Assignee: Technion Research & Development Foundation Ltd.
    Inventor: David Greenblatt
  • Publication number: 20140179550
    Abstract: Methods and composition for the screening and isolation of aglycosylated antibody Fc domain polypeptides. For example, in certain aspects methods for identifying aglycosylated Fc domains that bind to Fc receptors or preferentially bind to particular Fc receptors are described. Furthermore, the invention provides aglycosylated Fc domains that bind to Fc receptors with high affinity. Enhanced methods and media for prokaryotic based interaction screening are also provided.
    Type: Application
    Filed: December 13, 2013
    Publication date: June 26, 2014
    Applicant: RESEARCH DEVELOPMENT FOUNDATION
    Inventors: George GEORGIOU, Sang Taek JUNG