Abstract: Polymeric foams and elastomer/hydrogel bicontinuous composite structures derived from high internal phase emulsions and possessing shape-memory characteristics are disclosed, as well as processes for forming the same and uses thereof in, for example, manufacturing of various articles.

Abstract: A semiconductor device which produces at least 1 W/m2 two photon emission power per area, when operating at one or more temperatures greater than 20 K.

Abstract: Methods are provided for producing novel multicellular compositions comprising cancer cells together with pluripotent human stem cells, which are capable of proliferating and differentiating into various normal cell lines and tissue structures. These novel multicellular compositions are useful for investigating the properties of cancer cells in a normal human tissue microenvironment, and for studying interventions that will modulate these properties including devising, testing and screening therapeutic drugs.

Abstract: A method of in-situ adhering comprising providing pre-gel that comprises a mixture of at least one phenol-based compound and at least one water miscible polymer selected from at least one of a naturally existing form of a carbohydrate, a synthetically prepared form of carbohydrate and a salt of an anionic polysaccharide; spreading a layer of the pre-gel onto a first surface; adding a solid support, comprising at least one cross linking agent capable of interacting with the water miscible polymer to the pre-gel; and allowing the pre-gel to cure and adhere onto the first surface.

Abstract: A porous scaffold is disclosed, the porous scaffold comprising electrospun polymeric nanofibers, wherein an average diameter of a pore of the porous scaffold is about 300 ?m is disclosed. An average diameter of the polymeric nanofibers ranges from about 100 to 400 nm. The scaffold may comprise a plurality of particles, the particles being greater than about 1 ?m in diameter. Methods of fabricating scaffolds, methods for generating tissue and methods of using scaffolds for tissue reconstruction are also disclosed.

Abstract: A method of evaluating a semantic relatedness of terms. The method comprises providing a plurality of text segments, calculating, using a processor, a plurality of weights each for another of the plurality of text segments, calculating a prevalence of a co-appearance of each of a plurality of pairs of terms in the plurality of text segments, and evaluating a semantic relatedness between members of each the pair according to a combination of a respective the prevalence and a weight of each of the plurality of text segments wherein a co-appearance of the pair occurs.

Abstract: Disclosed are variant RTEF-1 polypeptides having an RTEF-1 amino acid sequence with one or more internal deletions, wherein the polypeptides reduce VEGF promoter activity. Some of the RTEF-1 polypeptides include an amino acid sequence that is at least 80% identical to the contiguous amino acids of 1) amino acids 24 to 47 of SEQ ID NO:15 and 2) each of SEQ ID NOs:16 and 17, but does not comprise the contiguous amino acids of SEQ ID NOs:8, 9, 11, or 12. Also disclosed are nucleic acids encoding the variant RTEF-1 polypeptides of the present invention. Pharmaceutical compositions that include the polypeptides and nucleic acids of the present invention are also disclosed. Methods of inducing cell contact inhibition, regulating organ size, and reducing intracellular YAP activity are also set forth, as well as methods of treating hyperproliferative diseases such as cancer using the pharmaceutical compositions of the present invention.

Abstract: The present invention provides HIV-derived lentivectors which are multiply modified to create highly safe, efficient, and potent vectors for expressing transgenes for gene therapy. The lentiviral vectors comprise various combinations of an inactive central polypurine tract, a stuffer sequence, which may encode drug susceptibility genes, and a mutated hairpin in the 5? leader sequence that substantially abolishes replication. These elements are provided in conjunction with other features of lentiviral vectors, such as a self-inactivating configuration for biosaftey and promoters such as the EF1? promoter as one example. Additional promoters are also described. The vectors can also comprise additional transcription enhancing elements such as the wood chuck hepatitis virus post-transcriptional regulatory element.

Abstract: The present application describes a sensor apparatus, especially an electronic nose, based on 2D films or 3D assemblies of cubic nanoparticles capped with an organic coating. The organic coating is modified with unique compositions of functional moieties, e.g. cyclodextrins, to provide the detection of volatile and non-volatile compounds derived from explosive materials, e.g. PETN, RDX, TNT etc. with very high sensitivity. The nose employs pattern recognition algorithms and methods, e.g. PCA, for detecting and quantifying specific explosive compounds.

Abstract: A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5? position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is selected from the group consisting of alkyl, cycloalkyl and aryl; and all other variables and features are as described in the specification.

Abstract: A method for determining an optimal location for positioning an image capturing device within a volume, the method including, obtaining a plurality of points to be visible from the image capturing device, performing inversion on points located in the vicinity of the plurality of points thus creating a computerized inversed object, each point in the vicinity of the plurality of point is translated to a corresponding point in the computerized inversed object, defining a convex hull of the inversed object, determining if a point of the plurality of points is visible from the viewpoint according to the position of its corresponding point on the convex hull relative to its neighbor points, repeating said determining for multiple locations within the volume, determining whether a predetermined set of points is visible from each location, selecting the optimal location of the image capturing device based on the results of said repeated determining.

Abstract: The present invention concerns methods of joint lubrication and/or prevention of cartilage wear making use of liposomes having membranes with at least one phospholipid (PL) of the group consisting of a glycerophospholipid (GPL) having two, being the same or different, C12-C16 hydrocarbon chain and a sphingolipid (SPL) having a C12-C15 hydrocarbon chain, the one or more membranes having a phase transition temperature in which solid ordered (SO) to liquid disordered (LD) phase transition occurs, the phase transition temperature being within a temperature of about 20° C. to about 39° C. for lubrication of joints.

Abstract: Methods and compositions concerning mutant flaviviruses with host-range phenotypes are provided. Nucleotide sequences that encode mutant flavivirus proteins are also provided. In certain aspects, viruses comprising these sequences display reduced replication in mammalian cells. In further aspects of the invention, flavivirus vaccine compositions and methods for vaccination against flavivirus infection are provided.

Abstract: The present invention provides HIV-derived lentivectors which are safe, highly efficient, and very potent for expressing transgenes for human gene therapy, especially, in human hematopoietic progenitor cells as well as in all other blood cell derivatives. The lentiviral vectors comprise promoters active to promote expression specific to cell types or tissues. Further, promoters are providing that are amenable to control by activators, enhancers, or repressors. These vectors are in a self-inactivating configuration for biosaftey. Additional promoters are also described. The vectors can also comprise additional transcription enhancing elements such as the wood chuck hepatitis virus post-transcriptional regulatory element, without any decrease in the specificity or control exerted by the promoters.

Abstract: A method for error detection includes storing in an associative memory multiple data entries, each data entry including a data item together with one or more check symbols computed with respect to the data item. A predetermined sequence of search keys is applied to the memory, thereby causing the memory to generate, in parallel, match results with respect to the data entries. The match results are processed in order to identify an error in at least one of the data entries.

Abstract: One aspect of the present invention relates to a method for synthesizing macro-sized nanostructures. The method in one embodiment comprises the steps of mixing an amount of TiO2 powders with a volume of an alkali or alkaline solution to form a mixture, and heating the mixture at a temperature higher than 160° C. for a period of time effective to allow TiO2-containing, macro-sized nanostructures to form, wherein the TiO2-containing, macro-sized nanostructures form in an environment that has no presence of a substrate that comprises Ti. These TiO2-containing, macro-sized nanostructures can be utilized to form a free standing membrane, and/or a three-dimensional (3D) structure.

Abstract: A method for writing data, the method may include evaluating current levels of multiple memory cells that belong to a certain set of memory cells or receiving an indication about the current levels of the multiple memory cells; encoding a new data unit to provide an encoded data unit to be written to the multiple memory cells while minimizing an amount of changes in levels of the maximum cell level among the multiple memory cells required for storing the encoded data unit; and writing the encoded data unit to the multiple memory cells.

Abstract: A device and method for producing electricity by harnessing sunlight to produce an amplified voltage signal, the device including: (a) a sealed chamber, defined by a transparent housing; (b) an excitable medium, disposed within the chamber, in which, when the medium is exposed to solar light having wavelengths in a range of 0.

Abstract: A method and apparatus for resolving conjunctive queries, comprising relational predicates and external predicates, such as XML predicates. The method and apparatus obtain results from a relational engine or from an external engine, and then use the obtained results as input for the other engine, so as to optimize the activity of the other engine. The process may repeat further times, with the results obtained by the other engine being input to the first engine. The method and apparatus further disclose handling value, being isomorphic hierarchical subtrees.

Abstract: A method of imaging a region containing an internal target tissue of a subject, comprising: inserting an intracorporeal ultrasound device to the subject; positioning an extracorporeal ultrasound device opposite to said intracorporeal ultrasound device, such that at least a portion of the region is interposed between said intracorporeal ultrasound device and said extracorporeal ultrasound device; using said intracorporeal ultrasound device and said extracorporeal ultrasound device to transmit ultrasonic radiation through the region; scanning the region using at least one of said intracorporeal ultrasound device and said extracorporeal ultrasound device; and analyzing said ultrasonic radiation so as to generate an image of the region by transmission ultrasound computerized tomography (TUCT).