Abstract: A 3D scanning device comprises: a digital light encoding unit comprising a digital micromirror device for encoding a rapidly changing shape signal onto a light beam directed to an object, a shape of said signal being selected such that distortions thereof by a contoured object reveal three-dimensional information of said contour; a detector synchronized with said digital light processing unit for detecting reflections of said light beam from said object, and a decoder for determining a 3D shape of said object from distortions of said signal in said detected reflections.

Abstract: Novel immunotoxins and methods of treating neoplastic diseases are provided. More specifically, immunotoxins comprised conjugation of a c-erbB-2 targeting moiety and a cell growth modulator are provided. These immunotoxins specifically and selectively kill tumor cells that over-express the c-erbB-2 protein. The novel immunotoxins would be useful in treating human mammary carcinomas, human ovarian carcinomas, lung carcinomas, gastric tumors, salivary gland adenocarcinomas, and colon adenocarcinomas.

Abstract: Sequences encoding two immunoreactive glycoproteins were cloned from Ehrlichia canis (p153 gene) and Ehrlichia chaffeensis (p156 gene). These two glycoproteins are species-specific immunoreactive orthologs that are useful as subunit vaccines and for serologic and molecular diagnostics for E. canis and E. chaffeensis.

Abstract: A porous scaffold is disclosed, the porous scaffold comprising electrospun polymeric nanofibers, wherein an average diameter of a pore of the porous scaffold is about 300 ?m is disclosed. An average diameter of the polymeric nanofibers ranges from about 100 to 400 nm. The scaffold may comprise a plurality of particles, the particles being greater than about 1 ?m in diameter. Methods of fabricating scaffolds, methods for generating tissue and methods of using scaffolds for tissue reconstruction are also disclosed.

Abstract: Methods and pharmaceutical compositions for treating cancer, particularly MDR cancer, which utilize polymeric compounds that are composed of a plurality of amino acid residues and one or more hydrophobic moieties are disclosed.

Abstract: The present invention relates to compositions and methods for producing hydrogen from water involving reacting metal particles with water in the presence of an effective amount of activator. In particular the invention pertains to compositions and methods for producing hydrogen upon reaction of metal particles selected from the group consisting of aluminum (Al), magnesium (Mg), boron (B), silicon (Si), iron (Fe), and zinc (Zn) with water, in the presence of an effective amount of an activator catalyst, wherein the activator is selected from the group consisting of: alkali metals, earth alkali metals, hydrides of alkali metals, hydrides of earth alkali metals, hydroxides of alkali metals, and hydroxides of earth alkali metals.

Abstract: An output buffer including a first differential input stage, a primary output stage, and a secondary output stage is provided herein. The first differential input stage respectively receives a first and a second input signals via a first and a second input terminals. The primary output stage includes a first and a second output stages. The first output stage provides at least one first level voltage according to the first and the second input signals, and the second output stage controlled by the first level voltage drives an output terminal of the output buffer to a target level. The secondary output stage includes a comparator and a third output stage. The comparator compares the induced currents in the first differential input stage, and thereby generates a control voltage. The third output stage controlled by the control voltage drives the output terminal of the output buffer to the target level.

Abstract: Articles of manufacturing, methods, devices and compositions for preventing or reducing tobacco-associated damage in a subject, and which utilize a metal ion chelating agent, a copper chelating agent, a penicillamine and/or a structural analog of penicillamine, with and without an additional antioxidant, are disclosed.

Abstract: An electronic apparatus at least including an audio-receiving circuit is provided. The audio-receiving circuit includes an audio receiver and a processor. The audio receiver receives a sound wave from a sound source, and generates a first audio signal containing a plurality of noises to the processor. The processor performs a signal processing of time reversal to the first audio signal to restore a sound sent at an original sound source, so as to filter noises in the first audio signal and output a second audio signal.

Abstract: The present invention provides a system and a method monitoring the health of structural joints by monitoring the strain developed near the joint due to perturbation applied away from that joint and comparing the monitored strain to strain which develops in a healthy joint due to comparable perturbation. The system for monitoring joints comprises: at least one near field strain measuring device installed near a monitored joint for monitoring the induced strain; at least one far field strain indicating device installed away from monitored joint indicating, measuring or producing the perturbation; and a data processor connected to said near field strain measuring device and to said near field strain measuring device for analyzing the response of the structure to the perturbation and determining the integrity of said joint. The method may also be used for detection and monitoring of off-joint crack initiation and edge delamination in composites.

Abstract: The present invention relates to a hierarchical system and method for task assignment (TA), coordination and communication of multiple Unmanned Aerial Vehicles (UAV's) engaging multiple attack targets and conceives an ad-hoc routing algorithm for synchronization of target lists utilizing a distributed computing topology. Assuming limited communication bandwidth and range, coordination of UAV motion is achieved by implementing a simple behavioral flocking algorithm utilizing a tree topology for target list routing. The TA algorithm is based on a graph-theoretic approach, in which a node locates all the detectable targets, identifies them and computes its distance to each target. The node then produces an attack plan that minimizes the sum of distances of the UAV's in the subtree of a given node to the targets.

Abstract: A human urocortin-related peptide with significant sequence homology to the CRF neuropeptide family was identified. A mouse cDNA was isolated from whole brain poly (A+) RNA that encodes a predicted 38 amino acid peptide protein designated herein as urocortin II. Both human URP and mouse Ucn II are structurally related to the other known mammalian family members, CRF and urocortin (Ucn). These peptides are involved in the regulation of the hypothalamic-pituitary-adrenal axis under basal and stress conditions, suggesting a similar role for URP and Ucn IL Synthesized Ucn-II and URP peptide binds with higher affinity to CRF-R2 than to CRF-R1 Ucn II and human URP appear to be involved in the regulation of body temperature and appetite and may play a role in other stress related phenomenon. These findings identify Ucn II and human URP as a new members of the CRF family of neuropeptides, which are expressed centrally and bind to CRF-R2.

Abstract: A method for multiplexing measurements of related values using predetermined numbers of sources having intensities and subject to noise, and at least one sensor subject to saturation, said multiplexing comprising measuring each of said related values under a plurality of different combinations of said sources, the method comprises: generating a first set of multiplexing combinations; constraining said first set with respect to said saturation; modifying said first set with respect to said noise until an optimum is found between respective intensities and noise, and measuring said variables by multiplexing said sources according to said modified set.

Abstract: A method of diagnosing melanoma and antibodies capable of same are disclosed. The method comprises contacting a cell of the subject with an antibody comprising an antigen recognition domain capable of binding to an MHC-I molecule being complexed with a tyrosinase peptide, wherein the antibody does not bind the MHC-I in the absence of the complexed peptide, and wherein the antibody does not bind the peptide in an absence of the MHC, under conditions which allow immunocomplex formation, wherein a presence of the immunocomplex or level thereof is indicative of the melanoma. Methods for treating melanoma and antibodies capable of same are also disclosed. Pharmaceutical compositions comprising antibodies are also disclosed.

Abstract: The present invention concerns methods of reducing the antigenicity of a proteinaceous compound while maintaining the compounds biological activity, as well as proteinaceous compositions with biological activity but reduced antigenicity. These methods and compositions have significant benefits to a subject in need of such compounds and compositions. Also included are modified toxin compounds that are truncated and/or possess reduce antigenicity. Such designer toxins have therapeutic, diagnostic, and preventative benefits, particularly as immunotoxins. Methods of treating cancer using these immunotoxins are provided.

Abstract: A peri-arterial blood flow booster apparatus for improving blood pressure and flow, to be implanted around a blood vessel of a patient. The booster comprises a pressure applying device (56) comprising at least one balloon (44), placed alongside a portion of the blood vessel and a restrainer (54) for restraining the balloon and providing counter-forces. It further comprises a control console (60) comprising: an inflating unit (66) for rapidly inflating and deflating the balloon, the inflating unit connected to the balloon; sensing means (68) for sensing electrocardiograph signals of the patient; a control unit (72) for controlling the operation of the inflating unit correlating to the electrocardiograph signals detected by the sensing means. When the balloon is inflated the restrainer forces it to compress the portion of the blood vessel preventing backflow and exerting forces on the blood vessel forcing blood within the portion of the blood vessel to flow antegradely.

Abstract: Methods for concentrating microorganisms in a liquid sample or depleting microorganisms therefrom, utilizing polymeric compounds having affinity to microbial cells that are composed of a plurality of positively charged amino acid residues and two or more hydrophobic moieties are disclosed. Also disclosed are devices for concentrating and methods for detection and identification microorganisms in a liquid sample.

Abstract: A fuel cell anode with high surface-to-volume ratio made of fibrous mat is disclosed. The fuel cell anode can be a fibrous mat produced by electrospinning method. The disclosed anode enables to fuel with saccharides fuel cells. In a preferred embodiment the fuel cell anode is provided wherein the anode is an electrospun fibrous mat, wherein the fibers are made of a polymer coated by a conductive material, preferably silver. This anode can also be made of fibrous mat, wherein the fibers are made of polymer fibers that contain metallic particles. A fuel cell that contains the disclosed anode and a fuel, such as glucose, is also disclosed in the present invention.

Abstract: The present invention provides IA derivative compounds of the formula: where the variables are described herein.

Abstract: The present invention provides methods compositions and methods for treating a hyperproliferative disease comprising disrupting Cripto/GRP78 complex formation in a hyperproliferative cell. In certain embodiments, an antibody and/or siRNA may be used to inhibit Cripto/GRP78 binding, optionally coupled with other cancer therapies. Also provided are methods for identifying therapeutic compounds which can selectively inhibit Cripto/GRP78 binding.