Abstract: A process for preparation of crystalline Form I of clopidogrel hydrogen sulphate, that include separating the crystalline Form I of clopidogrel hydrogen sulphate from a solution of clopidogrel freebase in a solvent, which is 2-propanol or 2-butanol is provided.
Type:
Grant
Filed:
March 11, 2005
Date of Patent:
August 10, 2010
Assignees:
Dr. Reddy's Laboratories, Inc., Dr. Reddy's Laboratories Limited
Abstract: A spring strut mounting for holding an upper end of a spring strut of a motor vehicle contains a spring strut dome with an articulation point for articulatedly connecting the upper end of the spring strut. The spring strut mounting further has a lower dome carrier which can be connected to a longitudinal member of the motor vehicle, and an upper dome carrier which can be connected to an A pillar of the motor vehicle, with the upper dome carrier engaging over the articulation point.
Abstract: A double-flow exhaust system for an internal-combustion engine, having exhaust-gas-carrying pipes and at least one muffler and catalyst housing. A separate end muffler is provided for each exhaust line, on which the end mufflers are both fluidically connected by at least one preferably mountable connection pipe.
Type:
Grant
Filed:
March 15, 2005
Date of Patent:
August 10, 2010
Assignee:
Dr. Ing. h.c. F. Porsche Aktiengesellschaft
Abstract: Solid pharmaceutical formulations are prepared using compositions comprising orlistat and having average particle sizes less than about 250 ?m.
Type:
Application
Filed:
September 17, 2008
Publication date:
August 5, 2010
Applicants:
DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
Inventors:
Soma Sekhar Kothamasu, Arti Sah, Uma Sowjanya Asapu, Maheswara Reddy Arumalla
Abstract: A zipper closure system for allowing one hand zipping of objects requiring sufficient compressive force to close is provided. The zipper closure system comprises a set of tracks having a row of teeth adapted to mate with each other, a plurality of sliders that are adapted to move along the row of teeth, a connector system comprising a plurality of extenders attached to the pull tabs that allow a user to move the plurality of sliders along the row of teeth, and a connector attached to a third pull tab, where the connector links the third slider with the first and second sliders. The zipper system further includes at least one pull ring and a stopping member.
Abstract: A roof arrangement (17) for a convertible (1) has a flexible convertible-top cloth (19) that can be removed by hand and stretched over a passenger compartment (16) between a cowl (9) and a rear end fastening device (18). A supporting bow (26) is beneath the convertible-top cloth (19) and is arranged in the transverse direction (FQ) of the convertible (1) at a distance behind the cowl (9). A tensioning device (32) keeps the convertible-top cloth (19) tensioned in relation to the cowl (9). The tensioning device (32) braces the convertible-top cloth (19) down adjacent to the supporting bow (26) and approximately in the vertical direction of the vehicle (FH) when the roof arrangement (17) is mounted on the convertible (1).
Type:
Application
Filed:
November 16, 2009
Publication date:
August 5, 2010
Applicant:
DR. ING. H.C.F. PORSCHE AKTIENGESELLSCHAFT
Abstract: A hybrid vehicle having a rear-mounted internal combustion engine, an electric energy accumulator, and at least one electric machine which is provided as a generator for charging the electric energy accumulator during an energy recovery phase and respectively as at least an additional drive to the internal combustion engine during a drive phase, wherein the internal combustion engine drives the rear axle of the hybrid vehicle, and wherein the electric machine, or each electric machine is provided at a distance from the rear axle, in particular in the region of the front axle.
Type:
Application
Filed:
May 23, 2008
Publication date:
August 5, 2010
Applicant:
DR. ING. H.C.F. PORSCHE AKTIENGESELLSCHAFT
Abstract: The invention provides a new enantioselective process for the preparation of (S)-pregabalin, or a pharmaceutical acceptable addition acid salt comprising: acid hydrolysis of the dioxolan ring of a chiral compound of general formula (I) to obtain compound of general formula (II); oxidation of compound (II) to obtain a compound of general formula (III) and transforming compound (III) into compound of general formula (IV); subjecting compound (IV) to basic hydrolysis to obtain a compound of general formula (V) which is reduced to obtain enantiomerically pure S-pregabalin. The invention also provides new chiral intermediates involved in the process.
Type:
Application
Filed:
July 17, 2008
Publication date:
August 5, 2010
Applicant:
LABORATORIOS DEL DR. ESTEVE, S.A.
Inventors:
Rosa M. Ortuno, Sandra Izquierdo, Helmut Heinrich Buschmann, Antoni Torrens Jover, Monica Garcia Lopez
Abstract: The present invention is directed to transdermal compositions and the uses thereof. These compositions include at least one of the following components: a C1-C6 dialkyl, C12-C30 dialkyl quaternary ammonium salt, a C12-C30 fatty acid, a nitrogenous organic base, C12-C30 fatty alcohol, monoglyceride or the reaction products thereof.
Abstract: Processes for preparing substantially pure docetaxel, new crystalline forms of docetaxel and processes for preparation thereof, processes for preparing docetaxel trihydrate, and pharmaceutical compositions comprising docetaxel.
Type:
Application
Filed:
July 3, 2008
Publication date:
August 5, 2010
Applicants:
DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.
Abstract: A reamer is proposed, having a basic body (3), at least one cutting tip (13) disposed essentially parallel to a face (11) of the reamer (1), which has a geometrically defined major cutting edge and a geometrically defined minor cutting edge (29, 27), and is held on a support surface (19) of the base body (3) by a tightening screw (39) that penetrates the cutting tip (13), where a back (17) of the cutting tip (13), which is polygonal in a bottom view, lies against the support surface (19), and having an adjustment device having an adjustment screw that acts on the cutting tip (13), which screw introduces adjustment forces into a side surface of the cutting tip (13). The reamer is characterized in that the ratio of the diameter (55) of an imaginary in-circle (53) that is tangential to the side edges (41, 41?, 45, 45?) of the back (17) of the cutting tip (13), relative to the thickness (d) of the cutting tip (13), lies in a range of 1.0 to 1.5, preferably in a range of 1.2 to 1.5.
Type:
Application
Filed:
September 2, 2008
Publication date:
August 5, 2010
Applicant:
MAPAL FABRIK FUR PRAZISIONWERKZEUGE DR. KRESS KG
Abstract: A loading space cover having a dimensionally stable housing and a flexible sheet like screen is rolled up in the housing. Fastening devices are disposed at the longitudinal end sides of the loading space cover. Each fastening device can be held releasably in associated loading-space fasteners of a motor vehicle. The fastening devices are of structurally simple and cost-effective design. Additionally, in the event of a crash, the fastening devices are held reliably in the loading-space fasteners and permit an energy-absorbing twisting of the loading space cover about its longitudinal axis.
Type:
Application
Filed:
January 29, 2010
Publication date:
August 5, 2010
Applicant:
DR. ING. H.C.F. PORSCHE AKTIENGESELLSCHAFT
Abstract: A movable vehicle roof has a plurality of segments which are movable relative to one another, in particular are displaceable and/or pivotable, and of which at least one has a core containing a filling structure forming cavities. The filling structure core is provided with a retaining part which engages around it in some regions at least on one side and, together with lateral elements disposed on it as a single piece, forms at least one intersecting point with the top framework.
Abstract: A method for operating an internal combustion engine in a motor vehicle, in which the internal combustion engine is switched off automatically as soon as it is not required, and in which the internal combustion engine is started automatically as soon as it is required or as soon as a timeout has expired. In order to increase the service life of the battery, the timeout is changed in dependence on a characteristic value which is correlated with the capacity of the battery.
Type:
Application
Filed:
January 29, 2010
Publication date:
July 29, 2010
Applicant:
DR. ING. H.C. F. PORSCHE AKTIENGESELLSCHAFT
Abstract: A device is provided for electrically adjusting a vehicle seat (1). The device has left and right articulated constructions (6, 6) arranged respectively on left and right sides (3, 4) of the vehicle seat (1). The device also has at least one electric motor (13) coupled to left and right gear mechanisms (10) for moving the respective left and right articulated constructions (6, 6) and left and right locking mechanisms (11) for locking the respective left and right articulated constructions (6, 6). The design permits a precise adjustment of the vehicle seat and secure locking of the vehicle seat in the event of a crash.
Type:
Application
Filed:
October 27, 2009
Publication date:
July 29, 2010
Applicant:
DR. ING. H.C.F. PORSCHE AKTIENGESELLSCHAFT
Inventors:
Tassilo Gilbert, Dieter Jungert, Joachim Müller
Abstract: A motor vehicle, in particular a passenger car, has an internal combustion engine and an engine control unit. In order to avoid insufficient lubrication, the engine control unit is configured and/or programmed in such a way that it reduces a rotational speed of the internal combustion engine if a predetermined maximum lateral acceleration of the vehicle is present for longer than a predetermined maximum time period.
Type:
Application
Filed:
November 20, 2009
Publication date:
July 29, 2010
Applicant:
DR. ING. H.C. F. PORSCHE AKTIENGESELLSCHAFT
Abstract: A device for the reinforcement of large-surface-area lateral sections of a rear bumper covering is effected by a supporting holder which is arranged pivotably on a load-bearing structure, is folded-in in a delivery position, is folded up in an assembly position and can be fastened with its free end to the vehicle body.
Type:
Application
Filed:
January 25, 2010
Publication date:
July 29, 2010
Applicant:
DR. ING. H.C. F. PORSCHE AKTIENGESELLSCHAFT