Abstract: Using a transformation based, at least in part, on a non-simple orthogonal matrix, data may be transmitted over a data bus in a manner that is resilient to one or more types of signal noise, that does not require a common reference at the transmission and acquisition points, and/or that has a pin-efficiency that is greater than 50% and may approach that of single-ended signaling. Such transformations may be implemented in hardware in an efficient manner. The transformation may be combined with methods from forward error correction to lower the required transmission power.

Abstract: In bus communications methods and apparatus, a first set of physical signals representing the information to be conveyed over the bus is provided, and mapped to a codeword of a spherical code, wherein a codeword is representable as a vector of a plurality of components and the bus uses at least as many signal lines as components of the vector that are used, mapping the codeword to a second set of physical signals, wherein components of the second set of physical signals can have values from a set of component values having at least three distinct values for at least one component, and providing the second set of physical signals for transmission over the data bus in a physical form.

Abstract: A semiconductor device for measuring ultra low currents down to the level of single electrons or low voltages comprises a first and a second voltage supply terminal, an input terminal for receiving an electrical current or being supplied with a voltage to be measured, a bipolar transistor having a base, an emitter and a collector, wherein a first PN junction is formed between the base and the collector and a second PN junction is formed between the base and the emitter, wherein the emitter is coupled to the input terminal and the base is coupled to the second voltage supply terminal, and wherein the first PN junction is designed for reverse biased operation as an avalanche diode, and a quenching and recharging circuit having a first terminal coupled to the first voltage supply terminal and a second terminal coupled to the collector of the bipolar transistors, the quenching and recharging circuit permitting operation of the first PN junction reverse biased above the breakdown voltage of the first PN junction.

Abstract: Light dispersing device comprising a slit element having a slit for exposure to electromagnetic radiation, wherein the slit element is configured and disposed for turning the slit between at least two positions. The light dispersing device is used together with a streak camera, whereby in a first position the slit is adjusted to influence the temporal resolution of the streak camera and in a second postion the slit is adjusted to influence the spectral resolution of the streak camera.

Abstract: Using a transformation based at least in part on a non-simple orthogonal or unitary matrix, data may be transmitted over a data bus in a manner that is resilient to one or more types of signal noise, that does not require a common reference at the transmission and acquisition points, and/or that has a pin-efficiency that is greater than 50% and may approach that of single-ended signaling. Such transformations may be implemented in hardware in an efficient manner. Hybrid transformers that apply such transformations to selected subsets of signals to be transmitted may be used to adapt to various signal set sizes and/or transmission environment properties including noise and physical space requirements of given transmission environments.

Abstract: A method to design a Networks on Chips (NoCs)-based communication system for connecting on-chip components in a multicore system, said system comprising several elements communicating through the communication system, said communication system comprising at least switches, said method comprising the steps of modelling the applications running on the multicore system, establishing the number and configuration of switches to connect the elements, establishing physical connectivity between the elements and the switches, for each two pairs of communicating elements: (a) a defining a communication path, (b) calculating metrics as affected by the need to render said path into physical connectivity, taking into account any previously defined physical connectivity, (c) iterating the steps a and b for a plurality of possible paths, (d) choosing the path having the optimal metrics, and (e) establishing any missing physical connectivity between the switches so that the selected optimal path occurs across physically conn

Abstract: A device and a method for creating a spatial dose distribution in a medium volume (22) are described. A laser system produces laser pulses (12) with a pulse length shorter than 200 fs (femtoseconds) and is capable to be focused to peak intensities greater than 10^18 W/cm^2 (watts per centimeter squared). An electron source (18) is capable of releasing a high-energy electron pulse (20), in particular the electrons having an energy greater than 100 MeV, upon irradiation with said laser pulses (12) propagating into the medium volume (22). The light paths (52, 56,58) of at least some of the laser pulses (12) are adjustable in such a way that high-energy electron pulses (20) are emitted from the irradiated at least one electron source on different trajectories (20,28,60,62) through the medium volume (22) thereby depositing their dose in the medium volume (22) according to a provided pattern.

Abstract: An infusion pump comprising a substance and pushing fluid inlet, a substance outlet, a central chamber communicating with said inlet and said outlet, and injecting means for injecting a substance into a biological object, wherein the infusion pump further includes a pushing fluid outlet in communication with the central chamber in such a way as to allow a pushing fluid to exhaust the pump. The outlet of the infusion pump is advantageously connected to the proximal end of a catheter, the distal end being inserted into the biological object. A sensor, e.g., an optical device, is preferably placed at the outlet of the infusion pump and checks that the outlet is free of gas. The infusion pump is preferably remotely controlled so that it can be placed in limited access locations. It is also preferably computer controlled.

Abstract: Coating for a medical device comprising cell-adhesive proteins having the ability to reduce fibrous reaction, said coating being in the form of separate islets having an individual area which is less than 12 ?m2 and wherein the distance between the islets is less than 50 ?m.

Abstract: Nanoparticles that activate complement in the absence of biological molecules are described. The nanoparticles are shown to specifically target antigen presenting cells in specifically in lymph nodes, without the use of a biological molecule for targeting. These particles are useful vehicles for delivering immunotherapeutics.

Abstract: An encoding/decoding apparatus and method using a low-density parity-check code (LDPC code) is disclosed. Basic column group information, serving as a set of information regarding positions of rows with weight 1, is extracted from a reference column in each column group of a predetermined parity-check matrix. Column group information transforms the positions of rows with weight 1 into positions whose lengths are within a required parity length. A parity-check matrix is generated according to the generated column group information. Data is encoded or decoded based on the generated parity-check matrix.

Abstract: A method for manufacturing the active plate of a flat matrix display screen, in which each cell comprises an electrode plate connected by a transistor to a first conductive line, comprising the steps of providing an outgrowth coated with an insulator of each first conductive line at the level of each cell; etching or making porous an end portion of each outgrowth; laterally growing, for example, by a VLS method, a PIP or NIN semiconductor structure in each end portion which has been etched or made porous; and establishing a contact at the free end of the semiconductor structure and forming a gate at the level of the median portion of the semiconductor structure.

Abstract: The invention relates to new proteins called alkylcytosine transferases (ACTs) derived from O6-alkylguanine-DNA alkyltransferase, and to substrates for ACTs specifically transferring a label to these ACTs and to fusion proteins comprising these. The substrates according of the invention are substituted cytosines of formula (I) wherein R1 is an aromatic or a heteroaromatic group, or an optionally substituted unsaturated alkyl, cycloalkyl or heterocyclyl group with the double bond connected to OCH2—; R2 is a linker; and L is a label or a plurality of same or different labels. The invention further relates to methods of transferring label L from these substrates of formula (I) to ACTs and ACT fusion proteins. The system of ACT-compound of formula (I) is particularly suitable for double labelling studies together with the known system O6-alkylguanine-DNA alkyltransferase (AGT)-benzylguanines.

Abstract: A method is described of forming a film of an amorphous material on a substrate (14) by deposition from a plasma. The substrate (14) is placed in an enclosure, a film precursor gas is introduced into the enclosure through pipes (20), and unreacted and dissociated gas is extracted from the enclosure through pipes (22) so as to provide a low pressure therein. Microwave energy—is introduced into the gas within the enclosure as a sequence of pulses at a given frequency and power level to produce a plasma therein by distributed electron cyclotron resonance (DECR) and cause material to be deposited from the plasma on the substrate. The frequency and/or power level of the pulses is altered during the course of deposition of material, so as to cause the bandgap to vary over the thickness of the deposited material.

Abstract: An inductive plasma applicator comprises a ferromagnetic inductively coupled source and an electrode with a hole pattern centered with respect to the plasma source. Such plasma applicator provides an efficient energy transfer to the plasma. The plasma applicator is preferably manufactured using a technology for producing electrical circuits. The electrode and a coil of the ferromagnetic inductively coupled plasma source are metal track portions formed on an insulating substrate. For example, the plasma applicator is manufactured using printed circuit board technology.

Abstract: A method to provide reliability, power management and load balancing support for multicore systems based on Networks-on-Chip (NoCs) and to efficiently implement architectural support for this method by introducing complex packet handling mechanisms is achieved by modifying the basic network interfaces attached to the cores of multicore computation systems. It also proposes policies to leverage the proposed hardware extensions. This aim is achieved with a method to manage the load of peripheral elements within a multicore system comprising several processing units accessing peripheral elements through a NoC, each processing unit and peripheral element attached to a Network Interface in charge of formatting and driving the packets sent to or received from the NoC, wherein, while considering at least two peripheral elements having a similar function, the Network Interface dedicated to a first peripheral element reroutes the incoming packets to a second Network Interface dedicated to a second peripheral element.

Abstract: A method for sample preparation for magnetic resonance measurements using Hyperpolarization by Dissolution Dynamic Nuclear Polarization, involves preparation of frozen beads of a first kind containing paramagnetic substances in addition to the solute under investigation; insertion of the frozen beads into a polarizing magnet; creation of enhanced polarization of nuclei in a magnetic field; heating of the sample to room temperature; transfer of the sample to an MR magnet; and carrying out an MR measurement. In addition, frozen beads of a second kind containing a reducing agent are prepared and inserted into the polarization magnet together with the frozen beads of the first kind. By this method, longitudinal and transverse relaxation times in NMR are extended and free radicals in hyperpolarized solutions are eliminated.

Abstract: The invention relates to an optical tweezer device including at least one light source and one three-dimensional optical trap, said optical trap comprising one focusing micro-mirror which is adapted to reflect and focus at least a portion of the light emitted by said light source.

Abstract: A method is described of forming a film of an amorphous material on a substrate by deposition from a plasma. The substrate is placed in an enclosure, a film precursor gas is introduced into the enclosure, and unreacted and dissociated gas is extracted from the enclosure so as to provide a low pressure therein. Microwave energy is introduced into the gas within the enclosure to produce a plasma therein by distributed electron cyclotron resonance (DECR) and cause material to be deposited from the plasma on the substrate. The said flow rate of the film precursor gas is altered during the course of deposition of material, so as to cause the bandgap to vary over the thickness of the deposited material.

Abstract: In previously known imaging devices as in still and motion cameras, for example, image sensor signal response typically is linear as a function of intensity of incident light. Desirably, however, akin to the response of the human eye, response is sought to be nonlinear and, more particularly, essentially logarithmic. Preferred nonlinearity is realized in image sensor devices of the invention upon severely limiting the number of pixel states, combined with clustering of pixels into what may be termed as super-pixels.