Abstract: The present invention concerns a method of sampling a test signal. The method comprises: acquiring training signals sampled at a plurality of sampling locations; running an optimization procedure for determining an index set of n indices, representing a subset of the sampling locations, that maximize a function, over the training signals, of a quality parameter representing how well a given training signal is represented by the n indices; and sampling the test signal at the sampling locations represented by the n indices.
Type:
Grant
Filed:
October 19, 2015
Date of Patent:
September 25, 2018
Assignee:
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
Inventors:
Volkan Cevher, Yen-Huan Li, Ilija Bogunovic, Luca Baldassarre, Jonathan Scarlett, Baran Gözcü
Abstract: The invention concerns a device (1) for aggregating cells comprising at least one cavity (2), wherein said cavity comprises a plurality of microwells (3) for receiving at least one cell, wherein each said well comprises a vertical sidewall and a curved bottom.
Type:
Application
Filed:
December 22, 2014
Publication date:
September 20, 2018
Applicant:
Ecole Polytechnique Federale De Lausanne
Abstract: A power flow control system for an interconnected power system, the interconnected power system comprising a plurality of electrical subsystems; an abstract framework configured to work as a utility maximizer under constraints (that applies to the electrical subsystems by specifying their capabilities, expected behavior and a simplified view of their internal state); and a plurality of agents. Each agent is responsible of one or a plurality of the electrical subsystems, comprises means configured to express an internal state of the electrical subsystem within a common system of coordinates, and has communication means configured to communicate among agents according to a protocol. The abstract framework means enables a composition of a set of the interconnected electrical subsystems into a further subsystem for which a further internal state is expressed within the same common system of coordinates used before, the further internal state being communicated with other agents according to the protocol.
Type:
Grant
Filed:
August 26, 2013
Date of Patent:
September 18, 2018
Assignee:
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
Inventors:
Jean-Yves Le Boudec, Andrey Bernstein, Mario Paolone
Abstract: The invention relates to a vehicle which includes at least four wheels and a base. Said wheels are attached in pairs at the base via connections and form a bogie consisting of a pair of wheels. Said bogies are rotatably hinged onto the base such that the pivot point of the path of the wheels is not physically present and said pivot point is located under the rotational axis of the wheels when the bogie is horizontal. The rotation of a bogie is transmitted by a transmission means to the other bogie such that the slant of each bogie in relation to the base forms an angle of identical but opposite value.
Type:
Grant
Filed:
March 11, 2015
Date of Patent:
September 11, 2018
Assignee:
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
Abstract: A medical device including an electric measurement circuit, in which are connected at least two sensors the impedance of which varies as a function of a sensed physical parameter, a source of electrical power for powering the electric measurement circuit, an antenna for emitting an electromagnetic field as a function of the impedance of the electric measurement circuit, each of the sensors being associated with a switch for short circuiting the sensor in the measurement circuit, the medical device further including a system for controlling the switches in order successively to command the opening or closing of the switches in determined configurations. The medical device may notably be able to be applied to the human body or implanted in the human body.
Type:
Application
Filed:
October 2, 2015
Publication date:
August 23, 2018
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE POLYTECHNIQUE, ECOLE NORMALE SUPERIEURE DE CACHAN
Inventors:
Abdul BARAKAT, Franz BOZSAK, Yvan Eric BONNASSIEUX, Bruno LE PIOUFLE, Olivier FRANCAIS, Bruno CARREEL
Abstract: The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.
Type:
Grant
Filed:
March 14, 2018
Date of Patent:
August 21, 2018
Assignee:
Ecole Polytechnique Federale de Lausanne (EPFL)
Abstract: The present invention relates to a bicistronic expression vector for silencing a gene specifically in astrocytes and neurons, comprising two expression cassettes comprising a first and a second silencer sequence, respectively, wherein the expression of said first silencer sequence within astrocytes is regulated by an astrocyte-specific promoter and the expression of said second silencer sequence within neurons is regulated by a neuron-specific promoter. In a preferred embodiment, said first and second silencer sequences are SOD1 silencer sequences. Pharmaceutical composition comprising said bicistronic vector and the use of the same in the treatment of motoneuron diseases are further described.
Type:
Application
Filed:
July 22, 2016
Publication date:
August 16, 2018
Applicant:
Ecole Polytechnique Federale De Lausanne (EPFL)
Inventors:
Julianne Aebischer, Bernard Schneider, Cylia Rochat
Abstract: Neuroprosthetic device for restoring daily-life action movements of upper limbs in patients suffering from motor impairments. The neuroprosthetic device comprises several non-invasive electrodes adapted to be fixed on a patient body, in a way as to stimulate at least two separate muscles which participate to the movement execution of the upper limb, an electrical stimulation device for injecting electrical current into said electrodes and a controller unit for regulating said currents through said electrodes. The neuroprosthetic device is characterized by the fact that the controller unit comprises transducing means which are adapted to convert an input current. The input current is regulated according to the intention to execute a movement, into a plurality of electrical currents defined in a way as to generate and modulate the movement execution, in order to generate complex goal-oriented movements for performing daily-living activities.
Type:
Grant
Filed:
October 17, 2014
Date of Patent:
August 14, 2018
Assignee:
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
Inventors:
Andrea Biasiucci, Andrea Maesani, Hédi Dimassi
Abstract: The invention relates to an arrangement for producing a proton beam. This arrangement is characterized in that it is constituted by a laser driven accelerator of protons adapted to produce a beam of relativistic protons of 0.5 GeV to 1 GeV with a current in the order of tens of mA, such as a current of 20 mA. The invention can be used for transmutating nuclear waste.
Type:
Grant
Filed:
September 11, 2013
Date of Patent:
August 14, 2018
Assignee:
ECOLE POLYTECHNIQUE
Inventors:
Tajima Toshiki, Gérard Mourou, Sydney Gales
Abstract: Several embodiments of the present disclosure relate to glycotargeting therapeutics that are useful in the treatment of transplant rejection, autoimmune disease, food allergy, and immune response against a therapeutic agent. In several embodiments, the compositions are configured to target the liver and deliver antigens to which tolerance is desired. Methods and uses of the compositions for induction of immune tolerance are also disclosed herein.
Type:
Grant
Filed:
June 17, 2016
Date of Patent:
August 14, 2018
Assignee:
École Polytechnique Fédérale de Lausanne (EPFL)
Abstract: Structure or device comprises a AlxGa1-xN or InyGa1-yN layer or substrate, a rare earth nitride epitaxial layer, and an AlzGa1-zN epitaxial interlayer between the rare earth nitride epitaxial layer and the AlxGa1-xN or InyGa1-yN layer or substrate. The interlayer is in direct contact with the rare earth nitride epitaxial layer and the AlxGa1-xN or InyGa1-yN layer or substrate.
Type:
Grant
Filed:
April 6, 2017
Date of Patent:
August 7, 2018
Assignee:
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
Abstract: An omnidirectional sensor array system, for example a panoptic camera, comprising a plurality of sensors arranged on a support of predetermined shape to acquire data, wherein said sensors are directional and wherein each sensor is attached to a processing node which comprises integrated electronics that carries out at least a portion of the signal processing algorithms locally in order to reduce the computational load of a central hardware unit.
Type:
Application
Filed:
January 23, 2018
Publication date:
August 2, 2018
Applicant:
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
Inventors:
Luigi BAGNATO, Laurent JACQUES, Pierre VANDERGHEYNST, Hossein AFSHARI, Alexandre SCHMID, Yusuf LEBLEBICI
Abstract: The invention relates to an ion thruster, comprising: a chamber, a reservoir, comprising a solid propellant (PS), housed in the chamber and comprising a conductive jacket provided with an orifice; means for forming an ion-electron plasma in the chamber, which means are able to sublime the solid propellant in the reservoir, then to generate said plasma in the chamber from the sublimed propellant coming from the reservoir through the orifice; a means for extracting and accelerating the ions and electrons of the plasma out of the chamber, which means comprises at least two grids at one end (E) of the chamber; a radiofrequency AC voltage source for generating a radiofrequency signal comprised between the plasma frequencies of the ions and of the electrons, arranged in series with a capacitor and connected, by one of its outputs and via this capacitor, to one of the grids, with the other grid being connected to the other output of said voltage source; said means for extracting and accelerating and said voltage
Type:
Application
Filed:
August 30, 2016
Publication date:
August 2, 2018
Applicants:
ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Abstract: The invention relates to electrochemical devices comprising complexes of cobalt comprising at least one ligand with a 5- or six membered, N-containing heteroring. The complex are useful as p- and n-dopants, as over of electrochemical devices, in particular in organic semiconductors. The complexes are further useful as over-discharge prevention and overvoltage protection agents.
Type:
Grant
Filed:
April 14, 2016
Date of Patent:
July 31, 2018
Assignee:
Ecole Polytechnique Federale de Lausanne (EPFL)
Inventors:
Julian Burschka, Florian Kessler, Etienne Baranoff, Mohammad Khaja Nazeeruddin, Michael Graetzel, Shaik Mohammed Zakeeruddin, Anders Hagfeldt, Marina Freitag, Fabrizio Giordano
Abstract: Systems and methods for imaging ear tissue include: directing illumination radiation to pass through an intact biological structure and be incident on ear tissue that does not include an exogenous fluorophore, at a plurality of locations, the illumination radiation including a plurality of light pulses each having a temporal duration of 500 femtoseconds or less; for each one of the plurality of locations, using a detector to detect radiation emitted from the location that passes through the intact biological structure; and forming an image of the tissue based on the detected radiation at each of the plurality of locations, where the emitted radiation corresponds to endogenous two-photon fluorescence of the tissue.
Abstract: The invention relates to a food supplement comprising or consisting of Archaebacteria, and particularly methanogenic Archaebacteria, to be used as a probiotic adjunct for animal feed. The supplement can be provided to e.g. farmed animals in addition to standard feed or as a food composition. Such a supplement is particularly useful in aquaculture and proves able in increasing animal growth rates, reducing animal susceptibility to parasitic infections and/or ameliorating animal faecal waste impact on environment. Also encompassed by the present invention are methods of manufacturing a composition comprising the bioactive food supplement as well as uses thereof.
Type:
Application
Filed:
March 16, 2016
Publication date:
July 12, 2018
Applicant:
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
Inventors:
Duncan-Bruce SUTHERLAND, Mario Michael ZAISS
Abstract: A photovoltaic module includes at least two photovoltaic cells in series, each rectangular cell including, respectively, a first rear thin film electrode, a photovoltaic stack having at least two active materials included between the rear electrode and a transparent conductive electrode made of a thin film, the electrode TC being capable of collecting and transmitting an electric current generated by the photovoltaic stack, the two photovoltaic cells being electrically connected in series by an electrical contact strip that is included between the electrode TC of the first cell and the rear electrode of the second cell. The local thickness of the electrode TC of the cell varies as a function of the distance to the electrical contact strip. Also described are methods for depositing and etching the transparent conductive film so as to simultaneously manufacture a plurality of cells for a single module.
Type:
Grant
Filed:
December 3, 2009
Date of Patent:
June 19, 2018
Assignees:
ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIC, TOTAL S.A.
Inventors:
Erik V. Johnson, Pere Roca I Cabarrocas
Abstract: The present invention relates to a method for assessing the quality, utility and applicability of a cell according to the said method comprising the following steps: a) analyzing the expression of the TEs of said cell in order to set up an expression profile of the TEs of said cell; b) comparing the expression profile obtained in step a) to a reference.
Type:
Application
Filed:
May 27, 2016
Publication date:
June 14, 2018
Applicant:
Ecole Polytechnique Federale de Lausanne
Inventors:
Didier Trono, Marc Friedli, Carmen Unzu Ezquerro
Abstract: Microfluidic system comprising a space for containing a liquid and at least one lateral chamber in communication with said space, said lateral chamber containing a metal electrode. The lateral chamber and the space are designed to be filled by the same or different liquid when the system is active.
Type:
Grant
Filed:
February 1, 2007
Date of Patent:
June 12, 2018
Assignee:
Ecole Polytechnique Fédérale de Lausanne (EPFL)
Inventors:
Philippe Renaud, Pontus Linderholm, Thomas Braschler, Nicolas Demierre, Urban Seger