Abstract: The present invention provides a computational method for designing artificial variants which have activity towards non-natural substrates. The present invention provides a special method to process stability evaluation results and creatively combines a process of calculating free energy barrier, which can improve the accuracy of the virtual screening of enzyme variants. The computational method disclosed by this invention greatly reduce the number of variants to be constructed and tested in the wet lab. In some cases, this method achieved the effect of enzyme engineering that cannot be achieved by traditional directed enzyme evolution methods.

Abstract: A system for maintaining a range of a gap between an ego vehicle and a preceding vehicle can include a processor and a memory. The memory can store a calculations module and an actuation module. The calculations module can cause the processor to determine a time, during a deceleration phase or an acceleration phase of a stop-and-go cycle of the preceding vehicle, when a preceding vehicle speed will equal a desired speed of the ego vehicle. The calculations module can cause the processor to determine: (1) in response to the time being during the deceleration phase, that the gap will be smaller than a desired maximum gap or (2) in response to the time being during the acceleration phase, that the gap will be larger than a desired minimum gap. The actuation module can cause the processor to change an ego vehicle speed to correct the gap.

Abstract: According to a preferred embodiment of the present disclosure, a project management device includes: a division unit configured to divide a project into n construction work packages (CWPs) based on a construction type constituting the project, a minimum unit area for managing the project, and design information; and a display unit configured to classify the n CWPs according to construction statuses and work front statuses and display the n CWPs in a grid form.

Abstract: There is provided a method for reconstructing a 3D image, comprising: obtaining Doppler ultrasound images depicting a blood vessel and measurement of blood flow in the blood vessel, and 2D camera images captured by a camera depicting fiducial objects randomly distributed within a viscous material and spaced apart by random distances on a surface of the individual, computing 3D coordinates within a world coordinate system for pixels of the Doppler images using an external reference of an ultrasound transducer pose computed by analysis of relative changes in locations of the fiducial objects within sequential camera images, and computing a respective estimated blood flow for pixels of the Doppler images at locations within the blood vessel, reconstructing a 3D image from 3D voxels computed from the 3D coordinates of pixels of the Doppler images, including respective estimated blood flow, wherein the 3D image depicts the blood vessel and blood flow.

Abstract: A substrate includes a dielectric structure, a conductive layer, a first hole and a second hole. The conductive layer is stacked on the dielectric structure. The first hole extends from a top surface of the conductive layer and exposes the dielectric structure. The second hole is spaced apart from the first hole, extends from the top surface of the conductive layer and exposes the dielectric structure. A first depth of the first hole is substantially equal to a second depth of the second hole. An elevation of a topmost end of the first hole is different from an elevation of a topmost end of the second hole.

Abstract: Proposed are an electrically conductive contact pin formed by stacking a plurality of metal layers and a manufacturing method therefor, in which the electrically conductive contact pin has improved physical or electrical characteristics.

Abstract: Systems and methods are provided for programmatically determining a remote operator of an autonomous or semi-autonomous vehicle. For example, some implementations may relate to assigning and reassigning a remote operator user in accordance with real-time changes in environmental characteristics of the distributed network of vehicles, remote operators, and (potentially) drivers.

Abstract: Systems, methods, and other embodiments described herein relate to predicting anomalous operation of a device and an associated remaining useful life (RUL) estimation. In one embodiment, a method includes acquiring usage information about the operation of an electronic device. The method includes determining whether the usage information indicates the presence of an anomaly in the operation of the electronic device according to an anomaly model. The method includes, responsive to detecting the anomaly, determining a remaining useful life (RUL) for the electronic device according to a RUL model. The method includes providing the RUL estimate.

Abstract: A system and method in communication with a sensor that can attach to objects placed on the roof of a vehicle acquires dimensional data to determine the position/orientation of the objects on the roof and determine the clearance of the vehicle based on the orientation of the object. The system recommends an orientation of the object to be placed in (e.g., based on the acquired dimensions of the object) to optimize aerodynamics and/or to reduce clearance.

Abstract: A hydraulic damper comprising a main cylinder, a piston slidably moveable within the main cylinder in compression and extension, the piston dividing the main cylinder into a main fluid chamber and an annulus fluid chamber, a piston rod extending from the piston through the annulus fluid chamber, and wherein the piston comprises a frequency sensitive damping (FSD) valve assembly configured to create a piston by-pass above a specified damper frequency, and further configured to lock the length of the hydraulic damper.

Abstract: A vehicle electronic system includes a vehicle ECU, a wire harness, and an accessory ECU. The wire harness includes a wire harness connector provided at an end of the wire harness. The accessory ECU includes a wire harness interface, a connection port, and a vehicle ECU interface. The wire harness interface electrically connects to the wire harness connector. The connection port electrically connects to an electronic device. The vehicle ECU interface electrically connects to the vehicle ECU. The accessory ECU is provided between the wire harness connector and the vehicle ECU.

Abstract: A vehicle and multi-purpose interior cabin lid for a vehicle that has use as a rear wall cover for one or more storage compartments in the interior cabin, a tailgate extension connectable to a vehicle tailgate, and a portable, freestanding table. The multi-purpose interior cabin lid member includes a base member, one or more coupling members, and one or more leg members coupled to the base member. The one or more coupling members are operable to selectively couple the base member in the interior cabin as a cover for the one or more storage compartments, and selectively couple the base member to a vehicle tailgate to serve as a tailgate extension. The one or more leg members are selectively coupled to the base member for movement between a retracted operating state when the base member is in an undetached operating state, and a deployed state to vertically support the base member on a support surface.

Abstract: An electronic device is disclosed. The electronic device includes a first component, a second component, and a first bridge component configured to electrically connect the first component with the second component. The first component is configured to transmit a first signal downwardly without passing the first bridge component and the second component is configured to transmit/receive a second signal to/from outside of the electronic device. A transmission speed of the second signal is higher than a transmission speed of the first signal.

Abstract: An artificial muscle assembly includes initiating actuators and an artificial muscle. The artificial muscle includes a housing including an electrode region and an expandable fluid region, and an electrode pair positioned in the electrode region. The electrode pair includes a first electrode and a second electrode fixed to respective first and second surfaces of the housing. At least one of the first electrode and the second electrode includes a central opening defining the expandable fluid region. The electrode pair is actuatable between a non-actuated state and an actuated state such that actuation from the non-actuated state to the actuated state directs a dielectric fluid into the expandable fluid region. Each initiating actuator is actuatable between a non-actuated state and an actuated state such that actuation from the non-actuated state to the actuated state applies a force against the electrode region of the artificial muscle.

Abstract: A multi-band LED disinfection system and a multi-band LED disinfection lamp are provided. The multi-band LED disinfection system comprises a multi-band LED disinfection device; and a control terminal, which is connected to and controls the multi-band LED disinfection device. The control terminal sends a wavelength band control command to the multi-band LED disinfection device according to a disinfection target, and the multi-band LED disinfection device drives LED beads of corresponding wavelength bands. Different wavelength bands of ultraviolet light can be provided to achieve the disinfection of various germs, which leads to better sterilization and disinfection effects. A control module can be used to switch between disinfection of a certain wavelength band and disinfection of superposed wavelength bands.

Abstract: A battery cell comprising a composite water-responsive safety layer and/or composite water- and pH-responsive safety layer to protect against tissue damage and/or electrolysis, when the battery cell is exposed to aqueous solution or tissue, is provided. The composite water-responsive safety layer and/or composite water- and pH-responsive safety layer is adapted to change from a non-electronically conducting state to an electronically conducting state.

Abstract: The present disclosure provides a semiconductor device package. The semiconductor device package includes an antenna layer, a first circuit layer and a second circuit layer. The antenna layer has a first coefficient of thermal expansion (CTE). The first circuit layer is disposed over the antenna layer. The first circuit layer has a second CTE. The second circuit layer is disposed over the antenna layer. The second circuit layer has a third CTE. A difference between the first CTE and the second CTE is less than a difference between the first CTE and the third CTE.

Abstract: A machine for processing tubing includes a chamber, a heater, a conveyor belt that passes through an interior space of the chamber, each of twenty or more links of the conveyor belt further comprising a generally planar outer-facing surface, each adjacent to a generally planar outer-facing surface of at least one other link, forming a generally planar composite surface along a substantially linear sub-path, and wherein a first link and a second link each comprises a first longitudinally-extending barricade adjacent a first side and a second longitudinally-extending barricade adjacent a second side of the at least one generally planar outer-facing surface, the barricades separated by a transverse distance that is less than one-half of the width of the conveyor belt, and wherein when the first and second link are in the substantially linear sub-path, a distance between the distal end of the first link and the proximal end of the second link is less than a total length of the substantially linear sub-path, such

Abstract: A semiconductor device package and a fabrication method thereof are disclosed. The semiconductor package comprises: a substrate having a first face and an opposing second face, wherein the first face is mounted with a first semiconductor component and a plurality of connectors; and a first shielding member covering the first semiconductor component and a first group of the plurality of connectors, while exposing a second group of the plurality of connectors.