Patents Assigned to EWHA University-Industry Collaboration Foundation
  • Cyanine derivatives having meso-reactive functional group at polymethine chain and preparation method thereof
    Patent number: 9151735
    Abstract: The present invention relates to a novel cyanne derivative having a meso-reaction functional group in a polymethine chain, and a preparation method thereof, and the cyanine derivative having the reaction functional group substituted at the meso site may be suitable for mass production thanks to a very simple synthesis method, have a very fast reaction rate because while a related art reagent for detection of nerve agents undergoes two steps of reactions, the cyanine derivative of the present invention undergoes only one step of reaction, have very excellent sensitivity, and be useful as an acid pH-activated ratiometric NIR probe because it is able to be activated in an acidic pH and is usable in an aqueous environment.
    Type: Grant
    Filed: January 7, 2013
    Date of Patent: October 6, 2015
    Assignee: Ewha University-Industry Collaboration Foundation
    Inventors: Juyoung Yoon, Guo Zhiqian
  • Magnetic ramdom access memory
    Patent number: 9135959
    Abstract: A magnetic random access memory includes multiple gate lines that are divided into a first gate line group and a second gate line group and arranged to be parallel to one another; multiple magnetic random access memory cells that are bonded to the gate lines in a direction intersected with the gate lines, respectively; multiple source lines that are bonded to one ends of switching devices included in the magnetic random access memory cells and arranged to be parallel to one another; and multiple bit lines that are bonded to one ends of magnetic tunnel junction devices included in the magnetic random access memory cells and arranged to be parallel to one another.
    Type: Grant
    Filed: April 9, 2013
    Date of Patent: September 15, 2015
    Assignee: EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION
    Inventor: Hyung Soon Shin
  • COMPOSITION FOR THERMOSTABILIZATION OF HUMAN SERUM ALBUMIN AND METHOD OF PREPARING THERMALLY STABILIZED HUMAN SERUM ALBUMIN USING THE SAME
    Publication number: 20150165000
    Abstract: The present invention relates to a composition for thermostabilization in the preparation of a human serum albumin formulation, comprising a fatty acid selected from the group consisting of C16 to C22 fatty acids or a pharmaceutically acceptable salt thereof; a method of preparing thermally stabilized human serum albumin, comprising: 1) adjusting a concentration of human serum albumin to 1 to 40 mg/mL; and 2) adding the fatty acid or pharmaceutically acceptable salt thereof to the human serum albumin; and a method of preparing a human serum albumin formulation, comprising adding the fatty acid or pharmaceutically acceptable salt thereof to human serum albumin and thermally treating the resultant.
    Type: Application
    Filed: December 18, 2013
    Publication date: June 18, 2015
    Applicant: Ewha University - Industry Collaboration Foundation
    Inventors: Dong Hae Shin, Gil Ja Jhon, Mi Sun Kim, Ji Min Park
  • Intraoral radiation type X-ray photographing apparatus and method thereof
    Patent number: 9050040
    Abstract: The present invention provides an X-ray imaging system for capturing an X-ray image of teeth and a jawbone, including a tubular X-ray generating unit placed in an oral cavity, and a movable X-ray detection unit placed in the oral cavity outer side region corresponding to the X-ray generating unit and corresponding to a face or an X-ray detection unit having a curved surface shape similar to the face.
    Type: Grant
    Filed: March 23, 2011
    Date of Patent: June 9, 2015
    Assignee: EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION
    Inventor: Rena Lee
  • Method of fabricating Ag-doped Te-based nano-material and memory device using the same
    Patent number: 9029248
    Abstract: A nano-ionic memory device is provided. The memory device includes a substrate, a chemically inactive lower electrode provided on the substrate, a solid electrolyte layer provided on the lower electrode and including a silver (Ag)-doped telluride (Te)-based nano-material, and an oxidizable upper electrode provided on the electrolyte layer.
    Type: Grant
    Filed: October 30, 2008
    Date of Patent: May 12, 2015
    Assignee: EWHA University-Industry Collaboration Foundation
    Inventors: William Jo, Ah-Reum Jeong
  • METHOD FOR TREATING PROSTATE CANCER BY USE OF PHARMACEUTICAL COMPOSITION CONTAINING A3 ADENOSINE RECEPTOR AGONIST
    Publication number: 20140371244
    Abstract: The present invention relates to a method by use of a pharmaceutical composition for preventing or treating inflammatory disease, colorectal cancer and prostate cancer, which contains an A3 adenosine receptor agonist, 2-chloro-N6-(3-iodobenzyl)-4?-thioadenosine-5?-N-methyluronamide (thio-Cl-IB-MECA), N6-(3-iodobenzyl)-4?-thioadenosine-5?-N-methyluronamide (thio-IB-MECA), or a pharmaceutically acceptable salt thereof. The pharmaceutical composition of the invention is significantly less toxic than conventional A3 adenosine agonists, and thus is useful for prevention or treatment of inflammatory disease. In addition, it more selectively inhibits the growth of androgen receptor-dependent or independent prostate cancer cells than other A3 adenosine receptor agonists and thus is useful for prevention or treatment of colorectal cancer or prostate cancer.
    Type: Application
    Filed: February 28, 2014
    Publication date: December 18, 2014
    Applicant: Ewha University - Industry Collaboration Foundation
    Inventors: Lak Shin JEONG, Sang Kook LEE, Hwa Jin CHUNG, Hyuk Woo LEE
  • NOVEL CYANINE DERIVATIVES HAVING MESO-REACTIVE FUNCTIONAL GROUP AT POLYMETHINE CHAIN AND PREPARATION METHOD THEREOF
    Publication number: 20140329331
    Abstract: The present invention relates to a novel cyanne derivative having a meso-reaction functional group in a polymethine chain, and a preparation method thereof, and the cyanine derivative having the reaction functional group substituted at the meso site may be suitable for mass production thanks to a very simple synthesis method, have a very fast reaction rate because while a related art reagent for detection of nerve agents undergoes two steps of reactions, the cyanine derivative of the present invention undergoes only one step of reaction, have very excellent sensitivity, and be useful as an acid pH-activated ratiometric NIR probe because it is able to be activated in an acidic pH and is usable in an aqueous environment.
    Type: Application
    Filed: January 7, 2013
    Publication date: November 6, 2014
    Applicant: EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION
    Inventors: Juyoung Yoon, Guo Zhiqian
  • COMPOSITION OF THE TREATMENT OF VASCULAR DISEASES OR KCa3.1 CHANNEL-MEDIATED DISEASES COMPRISING MODAFINIL OR DERIVATIVES THEREOF
    Publication number: 20140296333
    Abstract: The present invention relates to modafinil or derivatives thereof as a medicine for the treatment of vascular diseases or KCa3.1 channel (Ca activated K channel) mediated diseases and a novel use of the same. More specifically, the present invention relates to a pharmaceutical composition for the prevention or treatment of vascular diseases or KCa3.1 channel-mediated diseases comprising modafinil or a derivative of modafinil, or pharmaceutically acceptable salts thereof which relax blood vessels and inhibit KCa3.1 channel currents by increasing intracellular cAMP, a method for treating vascular diseases or KCa3.1 channel-mediated diseases using the composition and a health functional food composition for the prevention or improvement of vascular diseases or the KCa3.1 channel-mediated diseases comprising modafinil or a modafinil derivative compound, or sitologically acceptable salts thereof.
    Type: Application
    Filed: October 24, 2012
    Publication date: October 2, 2014
    Applicant: EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION
    Inventors: Suk Hyo Suh, Jae Chul Jung, Sei Kwan Oh
  • BUFFER CACHE APPARATUS, JOURNALING FILE SYSTEM AND JOURNALING METHOD FOR INCORPORATING JOURNALING FEATURES WITHIN NON-VOLATILE BUFFER CACHE
    Publication number: 20140297918
    Abstract: Disclosed herein are a buffer cache apparatus, a journaling file system, and a journaling method capable of incorporating journaling features based on nonvolatile memory. The buffer cache apparatus provides a data buffering function between a central processing unit (CPU) and storage. The buffer cache apparatus includes a plurality of cache blocks and a journal management unit. The plurality of cache blocks are configured as volatile or nonvolatile memory devices. The journal management unit maintains states of freezing for write-protecting dirty up-to-date cache blocks among the plurality of cache blocks.
    Type: Application
    Filed: April 15, 2013
    Publication date: October 2, 2014
    Applicant: EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION
    Inventor: Ewha University-Industry Collaboration Foundation
  • Anticancer-aiding compound, method for preparing the same, anticancer-aiding composition containing the same and method for reducing anticancer drug resistance using the same
    Patent number: 8846749
    Abstract: The present invention provides a novel xanthone derivative compound or a pharmaceutically acceptable salt thereof. The compound is useful as a chemosensitizer that reduces anticancer drug resistance.
    Type: Grant
    Filed: August 19, 2010
    Date of Patent: September 30, 2014
    Assignee: Ewha University-Industry Collaboration Foundation
    Inventors: Young Hwa Na, Young Joo Kwon, Hwa Jeong Lee, Song Wha Chae, Sang Wook Woo, Hee Ju Cho
  • COMPOSITION FOR DIAGNOSING OVARIAN CANCER METASTASIS USING CPG METHYLATION STATUS OF GENE PROMOTER AND USE THEREOF
    Publication number: 20140243218
    Abstract: The present invention relates to a composition, a kit and a method for diagnosing ovarian cancer metastasis or predicting the risk of metastasis by detecting methylation levels at CpG sites of one or more gene promoters selected from the group consisting of AGR2 (anterior gradient 2), CA9 (carbonic adj anhydrase 9), GABRP (gamma-aminobutyric acid receptor pi subunit), IFITM1 (interferon-induced transmembrane 1) and MUC13 (mucin 13).
    Type: Application
    Filed: February 20, 2014
    Publication date: August 28, 2014
    Applicant: Ewha University - Industry Collaboration Foundation
    Inventors: Jung-Hyuck AHN, Hye-Youn Sung, Woong Ju
  • Ethanol-resistant yeast gene, and use thereof
    Patent number: 8809060
    Abstract: The present invention relates to a gene associated with ethanol tolerance, and yeast strains and uses using the same. The yeast strain of this invention may growth under the condition not only with high-concentration ethanol, preferably 6-15% ethanol, but also in high osmotic pressure, preferably 30-40% glucose or sucrose. The present inventors developed yeast strains resistant to high-concentration glucose and ethanol, suggesting that they would be valuably applied to much effective ethanol production, and also be utilized as a superbacteria having tolerance to various stresses for ethanol production with high efficiency.
    Type: Grant
    Filed: November 24, 2010
    Date of Patent: August 19, 2014
    Assignee: Ewha University-Industry Collaboration Foundation
    Inventors: Won Ja Choi, Wan Kee Kim
  • METHOD AND SYSTEM FOR CHECKING SOFTWARE
    Publication number: 20140189449
    Abstract: A method and a system that checks software and includes a hooking module that collects process control block (PCB) information corresponding to each process on a kernel by being executed at the time of booting a system. In addition, the system includes a safety service module that searches and defends the defects of the process by being inserted into a memory region of the process based on the collected PCB information.
    Type: Application
    Filed: August 1, 2013
    Publication date: July 3, 2014
    Applicants: HYUNDAI MOTOR COMPANY, EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION, KIA MOTORS CORPORATION
    Inventors: Seung Yeun Jang, Jung Hoon Oh, Jung Suk Oh, Suk Young Rho, Sueng Wan Yang, Joo Young Seo, Byoung Ju Choi
  • METAL OXIDE-CARBONACEOUS HYBRID THIN FILM AND PREPARING METHOD THEREOF
    Publication number: 20140174514
    Abstract: The present disclosure relates to a metal oxide-carbonaceous hybrid thin film, a preparing method of the metal oxide-carbonaceous hybrid thin film, and a dye-sensitized solar cell using a photoelectrode including the metal oxide-carbonaceous hybrid thin film.
    Type: Application
    Filed: February 25, 2014
    Publication date: June 26, 2014
    Applicant: Ewha University - Industry Collaboration Foundation
    Inventors: Dong Ha Kim, Yoon Hee Jang
  • sp. microorganism and method for decomposing methane or odor-producing compounds using the same
    Patent number: 8748154
    Abstract: The present invention relates to a Sphingomonas sp. MD2 strain (KCTC 11845BP), a composition including the strain for decomposing methane or odor-producing compounds, a biocover or biofilter including the composition, a method for decomposing methane or odor-producing compounds using the composition, a system for decomposing methane or odor-producing compounds using the biocover or biofilter, and the use of the strain for decomposing methane or odor-producing compounds. According to the present invention, methane and odor can be effectively removed concurrently, and thus the cost required for the separate treatment of methane and odor can be reduced, and methane and odor-producing compounds in landfills or the like can be effectively decomposed.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: June 10, 2014
    Assignee: EWHA University-Industry Collaboration Foundation
    Inventors: Kyung Suk Cho, Jung Hee Lee, Kyung Eun Moon, Tae Gwan Kim, Sang Hyon Lee
  • Feed-forward ring oscillator
    Patent number: 8742855
    Abstract: Disclosed herein is a feed-forward ring oscillator. The feed-forward ring oscillator includes a plurality of delay cells for receiving a first differential input signal pair and a second differential input signal pair, and outputting a differential output signal pair. The delay cells are connected in a ring shape. Each of the delay cells receives a differential output signal pair of a delay cell of a previous stage as a first differential input signal pair and receives a differential output signal pair of a delay cell of a stage before the previous stage as a second differential input signal pair. Each of the delay cells comprises multiple independent gate field-effect transistors.
    Type: Grant
    Filed: December 28, 2009
    Date of Patent: June 3, 2014
    Assignee: EWHA University-Industry Collaboration Foundation
    Inventors: Hyung Soon Shin, Sung Min Park, Na Rae Jeong, Ji Sook Yun, Yu Jin Kim
  • PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF, AND COMPOSITION FOR PREVENTING AND TREATING OSTEOPOROSIS CONTAINING SAME
    Publication number: 20140128418
    Abstract: The present invention provides a pyrazole derivative compound and a pharmaceutically acceptable salt thereof. The compound of the invention is remarkably effective for preventing and treating osteoporosis.
    Type: Application
    Filed: February 27, 2012
    Publication date: May 8, 2014
    Applicant: EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION
    Inventors: Yun Soo Bae, Kee In Lee, Jee Hyun Lee, Soo Young Lee, Sun Choi
  • Method of detecting collisions in graphics processing unit
    Patent number: 8717382
    Abstract: The present invention relates to a method of detecting collisions on a Graphics Processing Unit (GPU). Each collision detection object Oi is projected onto a reference direction, thus obtaining an interval Ii represented by a set {mi, Mi}. Radix sorting based on obtained mi for all Oi, thus obtaining a sorted list L. The sorted list is swept, and then colliding pairs Pi are detected. All colliding pairs are configured into a single set, thus obtaining a final colliding pair P. On a GPU, SaP can be performed on a plurality of collision detection objects in parallel using the blocks of a plurality of threads.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: May 6, 2014
    Assignee: Ewha University-Industry Collaboration Foundation
    Inventors: Young Jun Kim, Fuchang Liu
  • Method for preparing microspheres and microspheres produced thereby
    Patent number: 8697127
    Abstract: The present invention relates to a method for preparing microspheres and microspheres prepared thereby, more particularly to a method for preparing a polymeric microsphere, including preparing an emulsion including a polymer compound, a drug, a water-insoluble organic solvent and a dispersion solvent and adding to the prepared emulsion a base or an acid to remove the water-insoluble organic solvent from the emulsion, a polymeric microsphere prepared thereby, and a composition for drug delivery including the microsphere. According to the present invention, a drug-containing polymer microsphere may be prepared quickly and simply without the solvent evaporation or solvent extraction process, thereby reducing water consumption and minimizing wastewater generation.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: April 15, 2014
    Assignees: Ewha University-Industry Collaboration Foundation, SK Chemicals Co., Ltd.
    Inventor: Hong Kee Sah
  • COMPOSITION FOR PREVENTING AND TREATING CARDIOVASCULAR DISEASES, CONTAINING PYRAZOLE DERIVATIVE
    Publication number: 20140088152
    Abstract: The present invention provides a composition comprising a pyrazole derivative compound and a pharmaceutically acceptable salt thereof. The composition is remarkably effective for preventing and treating cardiovascular diseases.
    Type: Application
    Filed: February 27, 2012
    Publication date: March 27, 2014
    Applicant: EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION
    Inventors: Yun Soo Bae, Kee In Lee, Jee Hyun Lee, Han Joong Jo, Jinoh Kim