Abstract: The present invention provides pyrazole derivative compounds and pharmaceutically acceptable salts thereof. The compounds of the present invention have an excellent effect of preventing and treating osteoporosis.

Abstract: Provided is an intraoral X-ray imaging apparatus having a camera, including: a frame; an X-ray irradiator which is installed to be supported by the frame and of which the one end portion is inserted into the oral cavity and which irradiates X-ray through an X-ray irradiation hole formed on the one end portion inserted into the oral cavity; a camera unit which is installed at the one end portion of the X-ray irradiator to image an interior of the oral cavity; a monitor unit which is connected to a camera unit to output the image captured by the camera unit; and an X-ray detector which is arranged to be separated from the X-ray irradiator in the frame so as to detect the X-ray irradiated from the X-ray irradiator outside the oral cavity. In the intraoral X-ray imaging apparatus having a camera, since the X-ray irradiator is located inside the oral cavity, it is possible to obtain an image having a high quality with a low X-ray dose and to avoid confusion in image diagnosis by removing a ghost image.

Abstract: Provided is an intraoral X-ray imaging apparatus for detecting X-ray outside an oral cavity, including: a frame; an X-ray irradiator which is installed to be supported by the frame and of which the one end portion is inserted into the oral cavity and which irradiates X-ray through an X-ray irradiation hole formed on the one end portion inserted into the oral cavity; and an X-ray detector which is arranged to be separated from the X-ray irradiator in the frame so as to detect the X-ray irradiated from the X-ray irradiator outside the oral cavity and which is movably installed so as to adjust a distance to the X-ray irradiator. In the X-ray imaging apparatus and an imaging method using the X-ray imaging apparatus, since the X-ray irradiator is located inside the oral cavity, it is possible to obtain an image having a high quality with a low X-ray dose and to avoid confusion in image diagnosis by removing a ghost image.

Abstract: The present invention provides pyrazole derivative compounds and pharmaceutically acceptable salts thereof. The compounds of the present invention have an excellent effect of preventing and treating osteoporosis.

Abstract: The present invention relates to benzoxazole derivatives represented by the Formula 1, which has an inhibitory activity against interleukin-6 (IL-6), a method for preparation thereof, and a pharmaceutical composition containing the same. The compound represented by the Formula 1 according to the present invention has a superior inhibitory activity against interleukin-6, and therefore, can be practically applied for prevention and treatment of diseases caused by abnormal interleukin-6 activity.

Abstract: The present invention provides pyrazole derivative compounds and pharmaceutically acceptable salts thereof. The compounds of the present invention have an excellent effect of preventing and treating osteoporosis.

Abstract: The present invention provides novel compounds of Chemical Formula I, a pharmaceutically acceptable salt thereof, or a hydrate or solvate thereof, a preparation thereof and a composition for the alleviation, prevention or treatment of osteoporosis, comprising thereof in an effective amount, and a method for alleviating, preventing or treating osteoporosis.

Abstract: Disclosed is a method for culturing myocardium-resident cardiac progenitor cells, comprising: embedding myocardial fragments into hydrogel; culturing the myocardial fragment into hydrogel; degrading only the hydrogel to recover cardiac progenitor cells grown out of the myocardial fragment to the hydrogel; and amplifying the cardiac progenitor cells in vitro. Also, the cardiac progenitor cells, a method for differentiating the same, and the use thereof as cell therapeutic agent for heart diseases are provided. In addition to possessing the potential to differentiate into cardiomyocytes, osteoblasts, adipocytes, chondrocytes, vascular endothelial cells, smooth muscle cells, neural cells, and skeletal muscle cells, the myocardium-resident cardiac progenitor cells can spontaneously differentiate into cardiomyocytes even in the absence of a special differentiation inducing agent.

Abstract: The present disclosure relates to an electrocatalyst for oxygen reduction including a silver/silver halide composite, a fuel cell including the electrocatalyst for oxygen reduction, and a method for preparing the electrocatalyst for oxygen reduction.

Abstract: A magnetic random access memory includes multiple gate lines that are divided into a first gate line group and a second gate line group and arranged to be parallel to one another; multiple magnetic random access memory cells that are bonded to the gate lines in a direction intersected with the gate lines, respectively; multiple source lines that are bonded to one ends of switching devices included in the magnetic random access memory cells and arranged to be parallel to one another; and multiple bit lines that are bonded to one ends of magnetic tunnel junction devices included in the magnetic random access memory cells and arranged to be parallel to one another.

Abstract: The present invention relates to a magnetic memory cell, which controls the magnetization direction of the free magnetic layer of a Magnetic Tunnel Junction (MTJ) device using a spin torque transfer, and enables the implementation of a magnetic logic circuit, in which memory and logic circuit functions are integrated. The magnetic memory cell includes an MTJ device (10) including a top electrode (11) and a bottom electrode (13), which are provided to allow current to flow therethrough, and a fixed layer (15) and a free layer (17), which are magnetic layers respectively deposited on a top and a bottom of an insulating layer (19), required to insulate the top and bottom electrodes from each other. A current control circuit (50) controls a flow of current flowing between the top and bottom electrodes, and changes a magnetization direction of the free layer according to an input logic level.

Abstract: 2-pyridyl-substituted imidazoles which are used advantageously in the treatment of diseases mediated by ALK 5 or ALK 4 receptor or both.

Abstract: The present invention relates to a method for preparing microsphere and microspheres produced thereby. The method comprises: mixing a water-insoluble organic solvent with a dispersion solvent; mixing a polymer compound, a drug and a water-insoluble organic solvent to prepare a dispersed phase; mixing the dispersed phase with the dispersion solvent mixed with the water-insoluble organic solvent to prepare an emulsion; and adding a base or an acid to the prepared emulsion. With the method, it is possible to prepare a drug-containing polymeric microsphere cost-effectively and conveniently.

Abstract: The present disclosure provides an apparatus and method for packet classification using a Bloom filter and includes determining a matching length of how long each field value of one or more fields in an input packet coincides with a field value of the corresponding field stored in a rule set by performing a field-by-field search on the fields in the input packet, and generating a tuple list made up of a combination of one or more of the matching length for the respective fields; selecting particular tuples existing in the rule set from the tuple list; filtering each of the selected tuples by using the Bloom filter; and searching for a best matching rule as a search pool exclusively within the tuples with the positive result of the filtering. According to the present disclosure, the object tuples to search can be substantially relieved to improve the searching performance.

Abstract: The present disclosure provides a method for producing a manganese oxide/graphene nanocomposite including synthesizing a manganese oxide/graphene nanocomposite through liquid phase reaction at a room temperature, a manganese oxide/graphene nanocomposite produced by the method, and an electrode material and a super-capacitor electrode including the manganese oxide/graphene nanocomposite.

Abstract: The present invention relates to a gene associated with ethanol tolerance, and yeast strains and uses using the same. The yeast strain of this invention may growth under the condition not only with high-concentration ethanol, preferably 6-15% ethanol, but also in high osmotic pressure, preferably 30-40% glucose or sucrose. The present inventors developed yeast strains resistant to high-concentration glucose and ethanol, suggesting that they would be valuably applied to much effective ethanol production, and also be utilized as a superbacteria having tolerance to various stresses for ethanol production with high efficiency.

Abstract: The present invention relates to a composition comprising an extract of Anemarrhena asphodeloides Bunge or the compounds isolated from the same, as an active ingredient. In particular, the extract and compounds have the excellent inhibitory effects on adipocyte differentiation, and thus can be used in a pharmaceutical composition and functional food for the prevention and treatment of lipid metabolism disorders.

Abstract: Disclosed is a test system and method that is configured to identify a position of a process control block, access the position of the process control block, and monitor performance factors related to the process control block.

Abstract: Vectors expressing kanA-kanB-kanK and other kanamycin production-related genes, Streptomyces<i/> species recombinant bacteria transformed with the vectors, a method of producing kanamycin antibiotics by the bacteria, and a new kanamycin compound produced by the bacterium are provided. With the use of the recombinant bacteria of the present invention, the direct fermentative biosynthesis of amikacin and tobramycin as semi-synthetic kanamycins is possible, and the yield of kanamycin B as a precursor of the semi-synthetic kanamycin is improved.

Abstract: The vertical silicon photomultiplier according to the present invention includes a trench electrode and a PN-junction layer perpendicular to the trench electrode forms and can maximize the quantum efficiency at optical wavelengths, 200˜900 nm in such a way that: it generates electric fields horizontal thereto, by applying a reverse bias voltage to between the trench electrode and the PN-junction layer, so that, although ultraviolet light does not reach the PN-junction layer but is incident on the surface, electron-hole pairs can be produced by the horizontally generated electric fields although and an avalanche breakdown can be thus generated, and it allows ultraviolet light, capable of being transmitted to a relatively deep depth, to react with the PN-junction layer.