Abstract: Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor.

Abstract: A manifold has at least one manifold aperture extending therethrough and selectively placed in fluid communication with a fluid source. An insertion structure has at least one interior cavity at least partially defined by a structure shell and is selectively placed in fluid communication with a corresponding manifold aperture. The insertion structure is configured for selective placement in a penetrating relationship with a patient tissue below a surface of the patient tissue. At least one shell perforation extends through the structure shell and places the interior cavity in fluid communication with a surrounding ambient space. At least one fluid path extends from the fluid source, through the manifold aperture, into the interior cavity, through at least one shell perforation, and at least one of a proximate relationship and a contacting relationship with the patient tissue beneath the outer surface thereof. A fluid is directed along the fluid path.

Abstract: A pulse train comprising chirped pulses can be used to excite a sample, such as for spectroscopic analysis. The respective chirped pulses can include a frequency sweep to establish a first frequency-domain comb. A width of frequency-domain comb peaks can be established at least in part by a total duration of the pulse train, and a bandwidth of the first frequency-domain comb can be determined at least in part by a bandwidth of the frequency sweep of the respective chirped pulses. A free-space or enclosed sample interaction region can be used.

Abstract: Provided is a delta-sigma modulator having a differential output, the modulator including a switched-capacitor integrator configured to generate a non-inverted integral signal and an inverted integral signal and also including a switched-capacitor circuit configured to sample an input signal based on a control signal and to integrate the feedback signal and the input signal based on the control signal and also a feedback circuit configured to generate the feedback signal.

Abstract: A polymer mixture emits a broad spectrum of visible light that appears white or near-white in the aggregate. The polymer mixture comprises two (or more) components in the active layer. A heavy atom, such as platinum and/or iridium, present in the backbone of the mixture acts via a spin-orbit coupling mechanism to cause the ratio of fluorescent to phosphorescent light emission bands to be of approximately equal strength. These two broad emissions overlap, resulting in an emission spectrum that appears to the eye to be white.

Abstract: Beam measurement values are computed by transforming a signal to a beamspace representation using a beamforming matrix that includes a plurality of columns that define a plurality of beams. A second plurality of beams is selected from the plurality of beams based on a power captured by each beam derived from the computed beam measurement values. For each beam of the second plurality of beams as a first beam, a spatial phase shift component and a temporal delay component is computed based on the fixed spatial angle associated with the first beam and a carrier frequency, a filter is defined using the spatial phase shift component and the temporal delay component, a beam measurement value associated with the first beam from the computed beam measurement values is selected, and the defined filter is applied to the selected beam measurement value to define a filtered value.

Abstract: The embodiments described herein pertain generally to a conductive polymer blend composition including a polymer-deaggregating agent and a method for preparing the same.

Abstract: A tomography system having a central processing unit, a system memory communicatively connected to the central processing unit, and a hardware acceleration unit communicatively connected to the central processing unit and the system memory, the hardware accelerator configured to perform at least a portion of an MBIR process on computer tomography data. The hardware accelerator unit may include one or more voxel evaluation modules which evaluate an updated value of a voxel given a voxel location in a reconstructed volume. By processing voxel data for voxels in a voxel neighborhood, processing time is reduces.

Abstract: The disclosure provides for peptides from syndecan 1 and methods of use therefor. These peptides can inhibit VLA-4 interaction with VEGFR2, thereby preventing tumor cell growth and tissue invasion.

Abstract: Disclosed herein are methods of treating a patient at risk of developing an inflammatory joint disease. In exemplary embodiments, the method involves inhibiting MCPIP levels in a patient in need, wherein said patient in need is exhibiting pre-arthritic or pre-osteoporotic symptoms.

Abstract: Methods, assays, and products for the detection of small molecules are provided. In one aspect, for example, a method of detecting a small molecule in a sample can include reacting together a first half of a DNA split aptamer having a first reactive group coupled thereto, a second half of a DNA split aptamer having a second reactive group coupled thereto, where the DNA split aptamer is selective for the small molecule, and a sample containing the small molecule. The first half and the second half bind to the small molecule and the first reactive group and the second reactive group react to form an aptamer ligation product of the first half and the second half. The method can also include assaying for the aptamer ligation product in order to detect the small molecule presence in the sample.

Abstract: Disclosed are an apparatus and method for modeling a three-dimensional (3D) shape. The apparatus for modeling a 3D shape includes a stacker configured to generate a skinned 3D model by forming an empty space inside a target 3D model and stack a plurality of 3D unit objects in the empty space; an influence calculator configured to calculate an influence of a change in a characteristic value of each of the plurality of 3D unit objects on mechanical properties of the target 3D model; a grouper configured to group the plurality of 3D unit objects into a plurality of groups according to the calculated influence; and a characteristic value calculator configured to determine an optimal characteristic value of the 3D unit object for each of the plurality of groups.

Abstract: This document describes, among other things, a computer-implemented method that includes accessing, by a computer system, electrogram data for a patient, wherein the electrogram data is obtained using one or more leads that sense physiological electrical activity of the patient. The computer system can identify one or more waveform features from the electrogram data, and one or more correlations between values of the one or more waveform features and analyte levels. One or more estimated analyte levels in the patient are determined based on 1) the one or more waveform features identified from the electrogram data and 2) the one or more correlations. The computer system can output information related to the one or more estimated analyte levels.

Abstract: Techniques for providing ancillary services to a power grid using customer premises such as commercial buildings. The techniques may involve receiving a regulation signal from a grid operator that is specific to a commercial building and modifying power consumption by at least one power consumption component in the building based on the regulation signal. The power consumption component may be a fan and/or a chiller of a Heating, Ventilation, and Air Conditioning (HVAC) system. The regulation signal may be tracked in a at least a portion of a frequency band from about 4 seconds to about 60 minutes, and the control architecture may depend on the portion of the frequency band.

Abstract: The present relates to a filter needle coupled between a fixation member having a needle for injecting a medical fluid after filtering foreign substances contained in the medical fluid and a disposable syringe, the filter needle includes an outer housing having a front end portion to which the fixation member is coupled and a rear end portion to which the disposable syringe is coupled and a filtering unit which is disposed inside the outer housing, and in which a medical fluid supplied from the fixation member to the disposable syringe is passed through as is, while a medical fluid supplied from the disposable syringe to the fixation member is filtered.

Abstract: The present invention relates to methods for assessing the risk of a patient for developing a potentially fatal cardiac dysrhythmia and for diagnosing Andersen's Syndrome. A tissue sample from a patient is obtained and the DNA or proteins of the sample isolated. From the DNA and protein isolates the sequence of the KCNJ2 gene or the Kir2.1 polypeptide can be obtained. The KCNJ2 gene or the Kir2.1 can be screened for alteration as compared to the wile-type sequence. An alteration in a copy of the KCNJ2 gene or a Kir2.1 polypeptide indicates that the patient has a high risk for developing acardiac dysrhythmia and can be diagnosed with Andersen's Syndrome. The invention also related to isolated nucleic acid molecules with one or more alterations as compared to the wild-type sequence.

Abstract: There are provided an apparatus and method for measuring thermal conductivity capable of easily and accurately obtaining an extent of thermal damage of a targeted tissue. The apparatus for measuring thermal conductivity in burns includes a thermal paper stacking member having a plurality of sheets of thermal paper stacked thereon to form layers, and a pressing member configured to press the stacking member so that the thermal paper is stacked and maintained in a closely adhered state. Here, an extent of thermal damage of the targeted tissue according to the depth can be calculated as an extent of thermal damage of the stacking member according to the depth.

Abstract: An apparatus and a method for wireless power reception are provided. A wireless power receiver includes a receiving unit configured to wirelessly receive a power. The wireless power receiver further includes a power consuming unit configured to consume the power, until a voltage applied to a load reaches a predetermined value, so that an amount of a power transferred from the receiving unit to the load is less than or equal to an initial accommodation power amount of the load.

Abstract: Disclosed is an optical communication receiver capable of compensating a DC offset while preventing an input load effect. The optical communication receiver includes an optical signal detector; an amplifier inputted with a photocurrent outputted from the optical signal detector; and a DC offset compensation unit provided therein with a third transistor and a fifth transistor which are connected in series to each other to prevent an input load effect, wherein the DC offset compensation unit compensates a DC offset by outputting at least a portion of DC current inputted to the amplifier to ground through the third transistor and the fifth transistor when the photocurrent is an over current more than a predetermined set value.

Abstract: ‘N13-32’ is a new and distinct early season clone of ‘Hamlin’ sweet orange. Fruit of ‘N13-32’ exhibit improved juice color and typical or better soluble solids than the industry standard for processing. Fruit juice of ‘N13-32’ produced a juice color score higher than 36, which is the minimum color score requirement to produce “Grade A” juice.