Abstract: Disclosed are high affinity antibodies or antigen binding fragments thereof, which bind an epitope that lies within the C terminal region of oncofetal antigen (OFA)/immature laminin receptor protein (iLRP), and which do not substantially cross-react with mature OFA/LRP. The antibodies may be conjugated to cytotoxic moieties to enhance their therapeutic efficacy. Methods of making the antibodies and therapeutic and diagnostic uses thereof are also disclosed.

Abstract: The present invention relates to an ?-helical cell-penetrating peptide multimer, a preparation method thereof and the use thereof, and more particularly, to a peptide multimer comprising a plurality of amphipathic peptides, a method for preparing the peptide multimer, a composition for preventing or treating HIV, which comprises the peptide multimer as an active ingredient, and a composition for intracellular delivery of a biologically active substance, which comprises the peptide multimer and the biologically active substance.

Abstract: A method of managing a cache includes storing first data of an upper level cache in a lower level cache, predicting a reuse distance level of second data having a same signature as the first data based on access information about the first data, and storing the second data in one of the lower level cache and a main memory based on the predicted reuse distance level of the second data.

Abstract: A phase converting device capable of use over a broad wavelength range, which may be used for optical beam transformations and combining, conversion of resonator and waveguide modes, correction of aberrations in optical systems, and selection of photons with specific phase profile. This provides significant advantages in high power laser systems. Large-mode-area fibers can be used to provide higher incident powers than can be achieved by single-mode fibers, reducing the number of elements in a system necessary to achieve the desired output. The profiles of these LMA fiber modes can then be converted from the undesired modes into the desired mode while combing their total power into a single beam.

Abstract: The present application relates generally to light emitting diodes and photodetectors as well as their methods of manufacture and use. In one exemplary embodiment, an integrated device may include a substrate, a light emitting diode formed on the substrate, and a photodetector formed on the substrate. In another embodiment, a device may include a light emitting diode formed on a substrate, and the light emitting diode may act as both a solid state light and as an optical transmitter.

Abstract: Polymer composite neutron detector materials are described. The composite materials include an aromatic polymer matrix, such as an aromatic polyester. Distributed within the polymer matrix are neutron capture agents, such as 6LiF nanoparticles, and organic or inorganic luminescent fluors. The composite materials can be formed into stretched or unstretched thin films, fibers or fiber mats.

Abstract: A delayed acknowledgement transmission method and an apparatus are provided for improving communication performance of a system and a terminal by delaying an ACKnowledgement (ACK) transmission of the terminal in a handover procedure. The method includes transmitting an acknowledgement corresponding to a segment immediately upon receipt of the segment, detecting a delay condition event which is triggered when a difference between a signal strength of the source base station and a neighboring base station is equal to or greater than a predefined offset, calculating a delay value for delaying acknowledgement transmission corresponding to the segment received after detecting the delay condition event, and transmitting the segment received after the detection of the delay condition event by delaying by as much as a time corresponding to the delay value. The apparatus is capable of avoiding a router's performance degradation and reducing a packet transmission delay and packet loss.

Abstract: Disclosed herein are methods of treating a patient at risk of developing or having a neurofibromatosis or a sporadic schwannoma. In exemplary embodiments, the method involves administering to a subject in need an effective amount of a LIMK modulating agent. Also disclosed are compounds newly identified to be inhibitors of Merlin-null Schwann cell proliferation and/or survival.

Abstract: An olecranon fracture fixation system includes an intramedullary core that is dimensioned for insertion in an intramedullary canal of the bone, and a hollow shell that is dimensioned for insertion in the intramedullary canal. The shell includes fixation elements that extend outwardly away from a proximal end of the shell. A fastener is provided for attaching the shell to the core in the intramedullary canal. When the core and shell are inserted in the intramedullary canal, the fixation elements extend away from the fracture line of the bone, and when the core and shell are attached in the intramedullary canal, the fixation elements engage an end surface of the end section of the bone. In one example version of the invention, the system is an olecranon fracture fixation system wherein the fixation elements are dimensioned to engage the triceps tendon and an end surface of the olecranon when the core and shell are attached in the intramedullary canal of the proximal ulna.

Abstract: The present invention is directed to methods of measuring the proliferative ability of individual patient cancer stem cells. The present invention provides a method for treating a cancer patient according to an assay of the individual patient's tumor's cancer stem cell sensitivity, by measuring the proliferative ability of cancer stem cells from the patient. By the methods of the present invention it is possible to treat individual cancer stem cells presented in tumor cells. Methods of detecting and enumerating cancer stem cells in hybrid spheroids comprised of fibroblasts and tumor cells are also provided by the present invention. The present invention also contemplates a method for drug and other treatment development, wherein the effects of a drug or combination of drugs or other treatments are determined on the individual patient's cancer stem cells.

Abstract: Technology for blind phase-shift keying (PSK) and quadrature amplitude modulation (QAM) identification of a received radio frequency (RF) signal is disclosed. One method can include: uniform sub-sampling the received RF signal to eliminate a phase contribution from a carrier frequency of the received RF signal; and computing a likelihood function of observed phase differences of the sub-sampled received RF signal of a phase sequence for each PSK modulation type. Another method can include: non-uniformly sub-sampling the received RF signal for a distribution of signal amplitudes of the received RF signal; and computing a likelihood function of the signal amplitudes of the sub-samples of the received RF signal for each modulation type.

Abstract: The present invention provides a preparation method of a metal matrix composite. The method comprises the following steps of: 1) pulverizing a solid carbon material to a micrometer size; 2) plastic deforming a metal matrix powder and dispersing the pulverized nanometer-sized carbon material into the metal matrix powder during the plastic deformation; 3) integrating the metal/carbon nano-material composite powder obtained in step 2) by using a hot forming process; and 4) heat treating the integrated bulk material at a predetermined temperature to form a composite having a metal-carbon nanophase, a metal-carbon nanoband formed by growth of the metal-carbon nanophase, or a metal-carbon nano-network structure formed by self-coupling of the metal-carbon nanoband.

Abstract: A method and apparatus for correcting location information of mobile communication terminals is disclosed. The apparatus for correcting location information of mobile communication terminals, includes: a handler to collect location measurement information of the mobile communication terminals, and environment information containing locations of base stations and arrangements of roads or buildings from a network; a database to store the location measurement information and the environment information; an analysis unit to analyze the location measurement information and the environment information to generate correction maps; a correction map database to store the correction maps; and a service unit to refer to the correction maps and to provide a corrected location estimate service, a corrected location measurement service, or a correction-value broadcast service to mobile communication terminals which request location services.

Abstract: The present invention provides a method to ensure that distributed resources of a power distribution system remain connected to the circuitry of the power distribution system when a fault occurs at a distributed resource node to assist in identifying the location of the fault by continuing to inject current from the distributed resources into the distribution system, wherein at least one of the distributed resources is a microturbine.

Abstract: The present invention provides a method to ensure that distributed resources of a power distribution system remain connected to the circuitry of the power distribution system when a fault occurs at a distributed resource node to assist in identifying the location of the fault by continuing to inject current from the distributed resources into the distribution system, wherein at least one of the distributed resources is a DC voltage distributed resource comprising a controllable voltage source converter.

Abstract: An apparatus for processing an invalid operation in a prologue and/or an epilogue of a loop includes a register file including a first region for storing a data validity value indicating whether data is valid or invalid, and a second region for storing the data; and a functional unit configured to determine whether an operation is valid or invalid based on a value of a first region of each of one or more input sources received from the register file, and output a destination including a value based on the value of the first region of each of the input sources.

Abstract: A method of synthesizing a metal oxide nanowire includes the steps of: combining an amount of a transition metal or a transition metal oxide with an amount of an alkali metal compound to produce a mixture; activating a plasma discharge reactor to create a plasma discharge; exposing the mixture to the plasma discharge for a first predetermined time period such that transition metal oxide nanowires are formed; contacting the transition metal oxide nanowires with an acid solution such that an alkali metal ion is exchanged for a hydrogen ion on each of the transition metal oxide nanowires; and exposing the transition metal oxide nanowires to the plasma discharge for a second predetermined time period to thermally anneal the transition metal oxide nanowires. Transition metal oxide nanowires produced using the synthesis methods described herein are also provided.

Abstract: A bushing adapted to secure an O-ring seal in position relative to an area of a passage permitting reciprocation of a push rod forms a generally circular bushing body with opposed end faces. The end faces are separated by a gap so as to provide the bushing with an approximately C-shaped structure. The bushing includes a plurality of locking elements resistant to axial loads imposed on the bushing by the push rod disposed at least substantially within a corresponding plurality of recesses distributed around a circumferential exterior of the bushing. Solid ribs are interspersed with the locking fingers to resist radial loads imposed on the bushing by the push rod during operation. The O-ring seal is secured in position within the passage area of the passage by an end surface of the bushing.

Abstract: The new variety ‘TH-906’ ripens in mid-May in southern Georgia. The fruit of the new variety ‘TH-906’ are medium to large, with good scar, and have good firmness and flavor. The new variety ‘TH-906’ is vigorous with an estimated chilling requirement of about 550 hours at or below approximately 7° C. The asexually reproduced variety is reliably propagated vegetatively.

Abstract: A new and distinct cultivar of the muscadine grape plant, Vitis rotundifolia Michx., named ‘Ga. 1-1-48’, which has: early ripening berries, typically beginning in the last week of July in Georgia; yellow-green berries; self-fertile flowers; berries that separate with a high percentage of dry stem scars; and berries that are large for a self-fertile cultivar.