Patents Assigned to Foundation
  • ROBOT FOR INSPECTION OF PIPELINE USING MULTI-OUTPUT DIFFERENTIAL MODULE
    Publication number: 20160223123
    Abstract: Provided herein is a robot for inspection of a pipeline using a multi-output differential module, the robot including a robot body configured to move along an inside of the pipeline, and having a driving power supply unit; a proceeding unit rotatably-connected to the robot body, and provided with a plurality of active proceeding units having proceeding wheels that proceed along an inner wall of the pipeline; and a power transmission unit supported against the robot body, connected to the driving power supply unit to transmit driving power to the active proceeding unit, and having the multi-output differential module that distributes the transmitted driving power to the active proceeding unit.
    Type: Application
    Filed: February 1, 2016
    Publication date: August 4, 2016
    Applicant: Research & Business Foundation SUNGKYUNKWAN UNIVERSITY
    Inventors: Hyouk Ryeol CHOI, Homoon KIM, Hyeong Min MOON, Chanmin PARK, Seung Ung YANG, Yun Seok CHOI
  • EPIDITHIODIOXOPIPERAZINE COMPOUND OR ITS DERIVATIVES, AND THE USE THEREOF
    Publication number: 20160222031
    Abstract: The present invention relates to an epidithiodioxopiperazine derivative represented by the following Chemical Formula 1 or its reduced derivative; a method for preparing a compound represented by Chemical Formula 1 having improved intracellular permeability and mimicking the activity of 2-Cys-Prx in its reduced form in the cells; a pharmaceutical composition for preventing or treating vascular diseases comprising an epidithiodioxopiperazine compound or its derivatives or pharmaceutically acceptable salts thereof as an active ingredient; a drug delivery device for local administration including the pharmaceutical composition; and a pharmaceutical composition for inhibiting melanoma metastasis comprising the epidithiodioxopiperazine compound or its derivatives or pharmaceutically acceptable salts thereof as an active ingredient.
    Type: Application
    Filed: May 23, 2014
    Publication date: August 4, 2016
    Applicant: EWHA University-Industry Collaboration Foundation
    Inventors: Sang Won KANG, Dong Hoon KANG, Doo Jae LEE
  • EDUCATION KIT FOR OPEN HARDWARE
    Publication number: 20160225281
    Abstract: An open hardware education kit is provided. The open hardware education kit comprises an expansion board. The expansion board comprises a plurality of metal terminals joinable with a magnet, a plurality of conductive connection wires respectively connected with the metal terminals, and a plurality of pin headers respectively connected with the connection wires. The plurality of pin headers are joinable with an expansion header of open hardware.
    Type: Application
    Filed: January 25, 2016
    Publication date: August 4, 2016
    Applicant: Korea University Research and Business Foundation
    Inventor: Sughui Kim
  • Sensorless control method and system for motor
    Patent number: 9407182
    Abstract: A sensorless control method and system for a motor are provided. The includes a back EMF observer that is configured to estimate a back EMF of the motor and an angle error calculator that is configured to calculate an electrical angle error considering iron loss of the motor based on the back EMF estimated by the back EMF observer. An angle error compensator is configured to compensate the electrical angle error calculated by the angle error calculator. An electrical angle for compensating the calculated electrical angle error is obtained through simulation or experiment for the motor. In addition, a PLL controller is configured to receive the compensated electrical angle to estimate an actual angle by reducing the electrical angle error due to the iron loss, and to operate the motor based on the estimated actual angle.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: August 2, 2016
    Assignees: Hyundai Motor Company, Postech Academy-Industry Foundation
    Inventors: Jaesik Yang, Sungwon Kim, Kitae Yeom, Taewon Hwang, Junwoo Kim, Kwang-Hee Nam
  • Synthesis and use of dual tyrosyl-DNA phosphodiesterase I (Tdp1)—topoisomerase I (Top1) inhibitors
    Patent number: 9402842
    Abstract: The invention described herein pertains to the synthesis and use of certain N-substituted indenoisoquinoline compounds which inhibit the activity Tyrosyl-DNA Phosphodiesterase I (Tdp1) or Topoisomerase I (Top1) or both, or otherwise demonstrate anticancer activity. Also disclosed are novel N-substituted indenoisoquinoline compounds and pharmaceutical compositions comprising the novel N-substituted indenoisoquinoline compounds.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: August 2, 2016
    Assignee: Purdue Research Foundation
    Inventors: Mark S. Cushman, Trung X. Nguyen, Martin M. Conda-Sheridan, Yves George Pommier
  • Small molecule inhibitors of PFKFB3 and glycolytic flux and their methods of use as anti-cancer therapeutics
    Patent number: 9403769
    Abstract: Small molecule inhibitors of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) having the following formula: Formula (1) are provided herein. Also provided herein are pharmaceutical compositions containing Formula I compounds, together with methods of treating cancer, methods of inhibiting PFK.FB3 enzymatic activity, methods of inhibiting glycolytic flux, and methods of treating tumors by administering an effective amount of a Formula I compound.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: August 2, 2016
    Assignees: Advanced Cancer Therapeutics, LLC, University of Louisville Research Foundation, Inc.
    Inventors: Pooran Chand, Jason A. Chesney, Brian F. Clem, Gilles H. Tapolsky, Sucheta Telang, John O. Trent
  • Compositions and methods for purifying Bax
    Patent number: 9403888
    Abstract: Disclosed are compositions and methods for purifying a Bax protein. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: August 2, 2016
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventor: Annette Khaled
  • Norovirus immunogens and related materials and methods
    Patent number: 9402891
    Abstract: The inventors have successfully developed a recombinant vesicular stomatitis virus which expresses the major capsid protein of human norovirus. Infection of mammalian cells with the recombinant vesicular stomatitis virus resulted in production of high level of human norovirus virus-like particles. Importantly, the inventors further demonstrated that recombinant vesicular stomatitis virus expressing the major capsid protein of human norovirus displayed attenuated virulence in mice and elicited a high level of human norovirus-specific humoral, cellular, and mucosal immune responses in mice model. Therefore, norovirus-immunogenic compositions are herein provided, as are materials and methods useful to make and use the compositions.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: August 2, 2016
    Assignee: Ohio State Innovation Foundation
    Inventors: Jianrong Li, Yuanmei Ma
  • Channel state information feedback apparatus and method in wireless communication system operating in FDD mode
    Patent number: 9408086
    Abstract: A Channel State Information (CSI) feedback method and apparatus is provided for transmitting, at a base station, the CSIs for plural transmit antennas with a limited amount resource and receiving, at a mobile station, the CSIs efficiently in a massive Multiple Input Multiple Output (MIMO) system operating in the Frequency Division Duplex (FDD) mode.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: August 2, 2016
    Assignees: Samsung Electronics Co., Ltd., Industry-Academic Cooperation Foundation, Korean National University of Transportation
    Inventors: Kiil Kim, Cheol Mun, Younsun Kim, Juho Lee, Hyojin Lee, Joonyoung Cho
  • Methods for forming nanocrystals with position-controlled dopants
    Patent number: 9406759
    Abstract: A doping method using a three-step synthesis to make high-quality doped nanocrystals is provided. The first step includes synthesizing starting host particles. The second step includes dopant growth on the starting host particles. The third step includes final shell growth. In one embodiment, this method can be used to form Mn-doped CdS/ZnS core/shell nanocrystals. The Mn dopant can be formed inside the CdS core, at the core/shell interface, and/or in the ZnS shell. The subject method allows precisely controlling the impurity radial position and doping level in the nanocrystals.
    Type: Grant
    Filed: August 30, 2007
    Date of Patent: August 2, 2016
    Assignee: University of Florida Research Foundation, Inc.
    Inventor: Y. Charles Cao
  • Composite material for a temperature sensor, and a method of manufacturing a temperature sensor using the same
    Patent number: 9404805
    Abstract: A composite material for a temperature sensor and a method of manufacturing the temperature sensor using the composite material are provided. The composite material contains four or more kinds of metal oxides combined with highly insulating materials to produce a material with semiconductor-like properties to more accurately measure a temperature at high temperatures in the range of 500° C. and above. The sensor includes electrode wires having a predetermined diameter inserted into the metal oxide of the temperature sensor when the metal oxide is press-molded to form the temperature sensor. Through the connection of the electrode wires to the temperature sensor device, disconnection of the electrode wires from the device even at a high temperature.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: August 2, 2016
    Assignees: Hyundai Motor Company, Industry-Academic Cooperation Foundation, Chosun University
    Inventors: Na Yun Ko, Tae Seung Lee, Jin Seong Park
  • Processor and memory control method for allocating instructions to a cache and a scratch pad memory
    Patent number: 9405683
    Abstract: A processor and a memory management method are provided. The processor includes a processor core, a cache which transceives data to/from the processor core via a single port, and stores the data accessed by the processor core, and a Scratch Pad Memory (SPM) which transceives the data to/from the processor core via at least one of a plurality of multi ports.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: August 2, 2016
    Assignees: Samsung Electronics Co., Ltd., Seoul National University Industry Foundation
    Inventors: Il Hyun Park, Soojung Ryu, Dong-Hoon Yoo, Dong Kwan Suh, Jeongwook Kim, Choon Ki Jang
  • System and method for parallel searching of a document stream
    Patent number: 9405820
    Abstract: A system and method for searching a document for a query pattern. A plurality of streams may be stored each including a linear sequence of nodes. Each stream may be associated with nodes having a common label in a data tree of the document. A query pattern may be searched for in the streams by executing a plurality of threads. Each of two or more of the threads may be used to search different sub-streams of the plurality of streams. Each of the different sub-streams searched for by each thread in each stream may be uniquely correlated with one or more disjoint sub-trees of a partition of the tree into a plurality of sub-trees. The two or more of the plurality of threads may be executed in parallel. A result of the query pattern search may be generated using at least one of the threads.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: August 2, 2016
    Assignee: Technion R&D Foundation Ltd.
    Inventors: Oded Shmueli, Lila Shnaiderman
  • Materials and methods for nerve grafting
    Patent number: 9402868
    Abstract: The subject invention pertains to compositions and methods for promoting repair of damaged nerve tissue using nerve grafts and preparation of nerve grafts. The compositions and methods of the subject invention can be employed to restore the continuity of nerve interrupted by disease, traumatic events or surgical procedures. Compositions of the subject invention comprise one or more chondroitin sulfate proteoglycan (CSPG)-degrading enzymes that promote axonal penetration into damaged nerve tissue and nerve graft. The invention also concerns methods for promoting repair of damaged nerve tissue using the present compositions and nerve tissue treated according to such methods. The invention also includes storage solutions for nerve tissue.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: August 2, 2016
    Assignee: University of Florida Research Foundation, Inc.
    Inventor: David F. Muir
  • Amidated dopamine neuron stimulating peptide restoration of mitochondrial activity
    Patent number: 9402875
    Abstract: The present invention relates to the use of novel proteins, referred to herein as amidated glial cell line-derived neurotrophic factor (GDNF) peptides (or “Amidated Dopamine Neuron Stimulating peptides (ADNS peptides)”), for treating brain diseases and injuries that result in dopaminergic deficiencies and mitochodrial dysfunction, e.g., reduced complex I enzyme activity.
    Type: Grant
    Filed: August 15, 2012
    Date of Patent: August 2, 2016
    Assignee: University of Kentucky Research Foundation
    Inventors: Luke H. Bradley, Don Marshall Gash, Greg A. Gerhardt
  • Patterned cardiomyocyte culture on microelectrode array
    Patent number: 9404140
    Abstract: The invention provides a culture of patterned cardiomyocytes, the culture including a support substrate bearing a multielectrode array, a negative surface resistant to cell attachment and deposited on the support substrate covering the multi-electrode array, a pattern ablated on the negative surface, a positive surface promoting cell attachment deposited on the pattern ablated on the negative surface; and cardiomyocytes adherent to the positive surface and growing aligned along the pattern ablated on the negative surface. The invention also includes a method of making the culture of patterned cardiomyocytes and a method of in vitro method of testing the effect of a compound on cardiac function by measuring electrical output from the patterned cardiomyocytes.
    Type: Grant
    Filed: November 3, 2010
    Date of Patent: August 2, 2016
    Assignee: The University of Central Florida Research Foundation, Inc.
    Inventors: Peter Molnar, Anupama Natarajan, Maria Stancescu, James Hickman
  • Pharmaceutical composition for preventing or treating diabetes containing TENC1 expression or activity suppressor
    Patent number: 9402856
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating diabetes or a complication of diabetes, which includes a TENC1 (tensin like C1 domain-containing phosphatase) expression or activity suppressor, and, more specifically, relates to a pharmaceutical composition for preventing or treating diabetes or a complication of diabetes, which either suppresses the degradation of IRS-1 (insulin receptor substrate-1) or suppresses the phosphorylation of IRS-1 due to the PTPase activity of TENC1.
    Type: Grant
    Filed: January 14, 2013
    Date of Patent: August 2, 2016
    Assignee: Postech Academy-Industry Foundation
    Inventors: Sung Ho Ryu, A Ra Koh, Mi Nam Lee, Hee Yoon Jeong, Yong Ryoul Yang, Pann Ghill Suh
  • Real-time assessment of absolute muscle effort during open and closed chain activities
    Patent number: 9402579
    Abstract: Methods and apparatus based on vibromyography technology are provided that overcome the substantial limitations of current VMG muscle assessment approaches. Specifically, embodiments of the invention provide a means by which clinicians and trainers can perform real-time muscle assessment during typical functional activities (activities involving substantial human movements). In some embodiments, the invention allows the artisan to simultaneously measure muscle forces being generated by complementary, supplementary, and/or antagonistic muscle pairs such that real-time muscle effort ratios can be calculated. In some embodiments, the measurements provide a means by which clinicians and trainers can diagnose musculo-skeletal injuries and pains associated with muscle imbalances.
    Type: Grant
    Filed: February 5, 2010
    Date of Patent: August 2, 2016
    Assignee: The Research Foundation for the State University of New York
    Inventors: Kenneth J. McLeod, Jason P. Cole
  • Media for culturing stem cells
    Patent number: 9404079
    Abstract: Well-defined, xeno-free culture media which comprise a TGF-beta isoform or the chimera formed between IL6 and the soluble IL6 receptor (IL6RIL6), which are capable of mainataining stem cells, and particularly, human embryonic stem cells, in an undifferentiated state are provided. Also provided are cell cultures comprising the culture media and the stem cells and methods of expanding and deriving embryonic stem cells in such well-defined, xeno-free culture media. In addition, the present invention provides methods of differentiating ESCs or EBs formed therefrom for the generation of lineage specific cells.
    Type: Grant
    Filed: June 4, 2013
    Date of Patent: August 2, 2016
    Assignee: Technion Research & Development Foundation Limited
    Inventors: Michal Amit, Joseph Itskovitz-Eldor
  • 3D laser ablation tomography
    Patent number: 9406167
    Abstract: A laser ablation tomography system includes a specimen stage for supporting a specimen. A specimen axis is defined such that a specimen disposed generally on the axis may be imaged. A laser system is operable to produce a laser sheet in a plane intersecting the specimen axis and generally perpendicular thereto. An imaging system is operable to image the area where the laser sheet intersects the specimen axis.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: August 2, 2016
    Assignee: The Penn State Research Foundation
    Inventors: Benjamin Hall, Jonathan Lynch, Edward W. Reutzel, Galen Lynch