Abstract: Electrochemical capacitors and methods for producing such electrochemical capacitors. The electrochemical capacitor can have an initial charged state and a cycled charged state and can include an anode, a cathode, and an electrolyte. The anode can include a first mixture having a first plurality of electrically conductive carbon-comprising particles having a first average porosity. The cathode can include a second mixture having a second plurality of electrically conductive carbon-comprising particles having a second average porosity greater than said first average porosity. The electrolyte can be physically and electrically contacting said anode and said cathode, and the first mixture in the cycled charged state can be substantially free of lithium metal particles and can further include a plurality of lithium ions intercalating the first plurality of carbon comprising particles. The mass ratio of the cathode and the electrolyte can be less than 1.

Abstract: This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker (30), preferably a retro-grate reflector (RGR), is placed on the head or other body organ of interest of a patient (P) during a scan, such as an MRI scan. The marker (30) makes it possible to measure the six degrees of freedom (x, y, and z-translations, and pitch, yaw, and roll), or “pose”, required to track motion of the organ of interest. A detector, preferably a camera (40), observes the marker (30) and continuously extracts its pose. The pose from the camera (40) is sent to the scanner (120) via an RGR processing computer (50) and a scanner control and processing computer (100), allowing for continuous correction of scan planes and position (in real-time) for motion of the patient (P).

Abstract: An approach is provided for manufacturing a nanostructure. A first thin film including a first block copolymer is formed on a substrate. A guide pattern is formed on the first thin film. A second thin film including a second block copolymer is formed between portions of the guide pattern. The second thin film is cured. The first block copolymer is a cylinder-type and the second block copolymer is a lamella-type.

Abstract: A method of diagnosing oral cancer or oral pharyngeal cancer in a subject in need thereof is provided. The method comprising determining a level or activity of at least one marker in a saliva sample of the subject, wherein a significant alteration in the level or the activity of the marker with respect to an unaffected saliva sample is indicative of the cancer, wherein the saliva marker is selected from the group consisting of Cyclin D1, phospho-Src, 8-oxoguanine DNA glycosylase (OGG1), Maspin, KI67 and translocator protein 18 kDa (TSPO).

Abstract: A method for providing an extended propagation ephemeris model for a satellite in Earth orbit, the method includes obtaining a satellite's orbital position over a first period of time, applying a least square estimation filter to determine coefficients defining osculating Keplarian orbital elements and harmonic perturbation parameters associated with a coordinate system defining an extended propagation ephemeris model that can be used to estimate the satellite's position during the first period, wherein the osculating Keplarian orbital elements include semi-major axis of the satellite (a), eccentricity of the satellite (e), inclination of the satellite (i), right ascension of ascending node of the satellite (?), true anomaly (?*), and argument of periapsis (?), applying the least square estimation filter to determine a dominant frequency of the true anomaly, and applying a Fourier transform to determine dominant frequencies of the harmonic perturbation parameters.

Abstract: A novel type of ultrathin cationic hydrogel coatings are provided that have high, quick and reversible swelling/shrinkage transitions and surface wettability in response to pH changes. The poly(4-vinyl pyridine) (PVP) hydrogel films are produced by selective cross-linking of PVP copolymers in layer-by-layer (LbL) films assembled by spin-assisted method. These multilayer hydrogels exhibit drastic and reversible 10-fold swelling when the pH is changed from neutral to acidic. The swelling amplitude of these coatings is controlled by varying cross-link densities within the films. The pH-responsive hydrogels open new prospects for developing “intelligent” materials with sharp stimuli-triggered responses for applications in sensing, transport regulation, and self-cleaning coatings.

Abstract: Disclosed is a cooperative spectrum sensing (CSS) method. The CSS method includes receiving, by a detector of secondary users, observation vectors which are use state information of a spectrum band allocated to a PU in a cognitive radio (CR) network, generating, by the detector, an analysis result value with respect to each of the observation vectors using GLRT with respect to order statistics of reception samples taking non-Gaussian noise into consideration, transmitting, by the detector, the analysis result value to a fusion center unit; and fusing, by the fusion center unit, the analysis result value to determine whether the spectrum band is used.

Abstract: A method of deformable image registration for thoracic 4-D computed tomography (CT) images includes: receiving, by a processing device, a set of thoracic 4-D CT images; and iteratively solving, by the processing device, an energy function applied to subsequent images of the set of thoracic 4-D CT images to transform the subsequent images into respective optical flow fields between the subsequent images, the energy function enforcing the following constraints on the subsequent images: intensity constancy; mass conservation; gradient constancy; and spatio-temporal smoothness.

Abstract: The invention provides luminescent solid-state compositions comprising difluoroboron beta-diketonates wherein the compositions can exhibit mechanochromic luminescence. The mechanochromic effect on the luminescence can be reversible, such as thermally reversible. Various solid-state forms of the invention can have emission spectra that differ from the properties of the respective difluoroboron beta-diketonate in solution. The mechanochromic effect can be stimulated by pressure such as handwriting, and can be reversed over a period of minutes to hours at room temperature. The invention also provides methods of making and methods of using the solid-state compositions, such as for sensors and for information displays for use in biological sensing, and in art, design, and consumer products.

Abstract: A method of producing stretchable conductive nanofibers includes: providing stretchable nanofibers; providing a metal precursor solution by dissolving metal precursors in a solvent that may swell the stretchable nanofibers; bringing the stretchable nanofibers into contact with the metal precursor solution or its vapor for a sufficient time for the metal precursors to penetrate into the stretchable nanofibers; and reduce the metal precursors inside the stretchable nanofibers to metal nanoparticles.

Abstract: The invention described herein pertains to substituted dibenzonaphthyridine compounds, pharmaceutical compositions, and formulations comprising the dibenzonaphthyridine compounds, their synthesis, and methods for their use in the treatment and/or prevention of cancer.

Abstract: An assay system designed to detect a protein biomarker in urine that is diagnostic for interstitial cystitis (IC). The presence of a 9 amino acid glycopeptide, antiproliferative factor (APF), in urine is unique to patients with IC. Urine samples from patients who exhibit symptoms consistent with IC are added to the assay system. Binding of APF to the cytoskeletal associated protein 4 (CKAP4) is positive for the presence of APF in urine and diagnostic for IC. The diagnostic system is a significant and surprising advance in diagnosis of IC and has commercial applications relevant to women and men who suffer from symptoms consistent with IC.

Abstract: The invention provides novel compositions based on a structure designated as “Honaucin A”, including Honaucin A variants and analogs, and pharmaceutical compositions, liposomes and nanoparticles comprising them, and methods of making and using them. In one embodiment, these Honaucin A compounds, and variants and analogs thereof are used to ameliorate (including to treat or prevent) inflammation. In one embodiment, these Honaucin A compounds, and variants and analogs thereof are used to ameliorate (including to treat or prevent) inflammation. In one embodiment, these Honaucin A compounds, and variants and analogs thereof are used as bacterial quorumsensing inhibitors. Accordingly, in alternative embodiments the compositions of the invention are used as anti-bacterial agents.

Abstract: A new class of paromomycin-derived aminoglycosides, which exhibit efficient stop-codon mutation suppression activity, low toxicity and high selectivity towards eukaryotic cells are provided. Also provided are chemical and chemo-enzymatic processes of preparing these paromomycin-derived aminoglycosides and intermediates thereof, as well as pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders.

Abstract: The present invention provides compositions and methods useful for diagnostic and imaging techniques for detecting and localizing the biomarker Plectin-1. The present invention provides multimeric peptide ligand complexes for targeting Plectin-1, such as the multimeric peptide ligand complex having the formula (?AKTLLPTPGGS(PEG5000))4 KKKKDOTA?A-NH2, to which imaging agents and/or therapeutic agents can be conjugated.

Abstract: Total knee replacements for hinged knee implants include a tibial member, a femoral member, a hinge assembly having a laterally extending axle configured to hingedly attach the femoral member to the tibial member, and a lock mechanism in communication with the hinge assembly. The lock mechanism is configured to (i) lock the femoral member in alignment with the tibial member for a full extension or other defined stabile walking configuration to thereby allow an arthrodesis or stiff knee gait and (ii) unlock to allow the femoral and tibial members to pivot relative to each other for flexion or bending when not ambulating.

Abstract: A support member for correcting tooth irregularities is provided. The support member includes: a main body that extends in a longitudinal direction and includes a hook portion formed on an end portion thereof; and a plurality of leg portions each of which extends in a radial direction from a central portion of the main body and has a through-hole formed in an end portion thereof, wherein each of the plurality of leg portions is obliquely formed with respect to a line perpendicular to the longitudinal direction of the main body. The support member may be simply fixed to a palatine bone by fixing a fixing screw to the palatine bone without cutting a mucus membrane and may maintain a stable fixed state because the plurality of leg portions are fixed in an area other than a midpalatal suture area.

Abstract: The invention provides coding and promoter sequences for an STF gene, which affects lamina expansion in plants. Vectors, transgenic plants, seeds, and host cells comprising a heterologous STF gene are also provided. Additionally provided are methods of altering biomass in a plant using the STF gene.

Abstract: The present invention relates to a method for screening an anticancer compound and an anticancer compound screened using the method, and more particularly, to a method for screening an anticancer compound, the method comprising: culturing cancer cells expressing the oncogenic protein transmembrane 4 L6 family member 5 (TM4SF5), expressed as the polypeptide of SEQ ID NO: 2, treating the cancer cells with an anticancer candidate, and determining that the anticancer candidate is an anticancer substance when the candidate exhibits antagonistic activity against tumor formation and metastasis based on several events through the molecular mechanism of TM4SF5. The present invention also relates to chalcone compounds screened to have anticancer activity using the method, and an anticancer composition comprising the compound as an effective ingredient.

Abstract: A bone graft composition includes a biologically-resorbable cement and a plurality of processed bone particles, where each of the bone particles have a shape configured to interconnect with adjacent bone particles. A method for treating a bone defect using the bone graft compositions includes providing the bone graft composition and administering an effective amount of the bone graft composition to a site of a bone defect in a subject. Kits including a biologically-resorbable cement powder and a plurality of processed bone particles are also provided.