Abstract: A system and method for personalized dosing of a pharmacologic agent include: executing, using a processing device, a plurality of dosing regimen program modules to determine a respective plurality of dose sets in response to receiving, from an input device, a target response value for a patient; and executing, using the processing device, a dosing selection algorithm module, following executing the plurality of dosing regimen program modules and in response to receiving from the input device a response profile and a monitoring frequency of the patient, to determine a recommended dose set computed as a combination of the plurality of dose sets weighted by degrees of matching computed using fuzzy sets and the response profile.

Abstract: A method of additive manufacturing is described wherein powder material is spread in a layer, contacted with a binding polymer and cured with light. Also described is a system for preparing additive manufactured objects such as molds, tools and composites.

Abstract: A system may include a solar cell and a modulator connected to an output of the solar cell. The system may receive a signal. When the signal being in a first state corresponding to modulation, the modulator may modulate voltage output of the solar cell and cause the solar cell to perform optical transmission. When the signal is in a second state corresponding to energy harvesting, the modulator to cease modulation of the output of the solar cell.

Abstract: Provided herein are methods of potentiating an effect of an anti-cancer drug in a subject diagnosed with cancer, the method including administering to the subject a combination therapy including: an effective amount of 7-ethynyl-5-(2-fluorophenyl)-1-methyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one (BZD-1); and an anti-cancer drug.

Abstract: Provided is a radar signal processing method based on Orthogonal Frequency Division Multiplexing (OFDM). The method includes transmitting an OFDM transmission signal to at least one target, receiving an analog reception signal reflected from the at least one target, converting the analog reception signal into a digital reception signal, obtaining a first velocity of the at least one target based on the digital reception signal, and processing the digital reception signal based on the first velocity to obtain a recovery signal having reduced inter-channel interference.

Abstract: The present invention relates to a novel anticancer peptide. The anticancer peptide inhibits cancer cell proliferation and metastasis, induces cell death, and relieves drug resistance, and thus may be utilized for an anticancer use and an anticancer adjuvant.

Abstract: Provided is an underlayer which may improve the resolution and sensitivity of a resist film, suppress the collapse of a resist pattern and have improved etching resistance. The underlayer includes a crosslinked material of tin-oxo nanoclusters represented by Formula 1. [(R—Sn)12O14(OH)6]2+[Rx?]2??[Formula 1] In Formula 1, R is an alkyl group of 1 to 20 carbon atoms, and Rx? is a counter anion and an alkylbenzene sulfonate anion.

Abstract: This patent document provides a caged catalyst comprising a catalyst encapsulated in a cage compound of Formula I represented [ZrIV6O4(OI)4(linker)6]). The catalysts demonstrated excellent activities and size selectivity in a model RCM reaction, suggesting successful encapsulation into MOFs. ROMP of cyclopentene mediated by G3@UiO-67 achieved significantly higher molecular weight and lower dispersity than the counterpart mediated by the free catalyst. The ultra-high molecular weight polymers generated by the encapsulated catalysts demonstrated significantly improved mechanical and adhesive properties compared to the low molecular weight counterparts and commercial polymers. The simplicity and generality make this method readily applicable to the ROMP of a wide range of low-strain cyclic olefins.

Abstract: The present application relates to vanadium compounds. More specifically, the present application relates to pharmaceutical compositions comprising vanadium salts, use thereof and methods using the same. The present application also includes compositions comprising vanadium compounds and a therapeutic or prophylactic virus providing for increased virus infection, spread, titer, activity, cytotoxicity and/or immunotherapeutic activity.

Abstract: A temperature-responsive hydrophilic-hydrophobic conversion surface has a surface property that is hydrophobic at a low temperature and is converted to be hydrophilic when the temperature rises. Accordingly, by applying the conversion surface to the fins of a heat exchanger, frost formation can be delayed in a low temperature environment due to the hydrophobicity, and remaining meltwater can be easily dried due to the conversion of the surface from hydrophobic to hydrophilic when the temperature is raised for defrosting. Therefore, the surface property of the fins of a heat exchanger is automatically converted according to the temperature and exhibits only favorable advantages at respective temperatures, so that heat transfer performance and power efficiency of the heat exchange can be effectively improved.

Abstract: The present invention relates to a Leukocyte-specific protein 1 (LSP1)-deficient T cell-based anticancer immunotherapy. According to the present invention, tumor growth, tumor volume and size were reduced by means of LSP1 knockout, and LSP1 deficiency in T cells increases the number, distribution frequency, migration, and invasion of T cells, and increases the production of an anti-tumor cytokine to inhibit tumor growth and enhance tumor-killing ability. Thus, the present invention can be used for T cell-based immunotherapy.

Abstract: A plasma process monitoring apparatus using terahertz waves is provided. A plasma process monitoring apparatus using terahertz waves may comprise: a first monitoring module disposed in a direction parallel to the width direction of a wafer on the outside of a plasma chamber in which the wafer is introduced and monitoring plasma formed inside the plasma chamber during a plasma process for forming a film on the wafer by using terahertz waves; and a second monitoring module disposed outside the plasma chamber in the thickness direction of the wafer so as to face the wafer and monitoring the wafer on which a film is formed on a surface through the plasma process by using the terahertz waves.

Abstract: The present invention relates to a composition, a fiber or a fragrance composition for improving cognitive ability or memory ability, containing a fermented Perilla frutescens extract. In addition, the present invention relates to a composition for preventing, alleviating or treating cognitive ability- or memory ability-related diseases, containing a fermented Perilla frutescens extract. Furthermore, the present invention relates to a method for treating cognitive ability- or memory ability-related diseases, comprising a step of administering a fermented Perilla frutescens extract to a patient with a cognitive ability- or memory ability-related disease. Compared to an unfermented Perilla frutescens extract, a fermented Perilla frutescens extract of the present invention significantly increases cognitive ability or memory ability, thereby being effectively usable as a composition for improving cognitive ability or memory ability.

Abstract: Disclosed are an integrate-and-fire neuron circuit implemented to enable an integrate-and-fire operation with only a small number of devices by using bistable resistance characteristics of the same two heterojunction NPN devices, unlike a CMOS-based integrate-and-fire neuron circuit having a complex structure, and an operation method thereof. In one or more aspects, an integrate-and-fire neuron circuit and an operation method thereof can increase neuron integration in a system by implementing an integrate-and-fire operation of neurons using only three transistors and two capacitors, or two transistors, one resistor and one capacitor, can improve the efficiency of spiking neural network learning by controlling a fire threshold point of neurons through regulation of a gate voltage of the same two NPN devices, and can expect an increase in energy efficiency of the entire system through inhibition of excessive fire by implementing excitatory and inhibitory post-synaptic potentials.

Abstract: The disclosure provides a method for manufacturing a cation exchange membrane for a fuel cell, comprising the steps of providing a first hydrocarbon-based polymer having a sulfonic acid group; forming a mixture by mixing the first hydrocarbon-based polymer with 3,4-ethylenedioxythiophene (EDOT); adding an oxidizing agent to the mixture to prepare a cation exchange membrane; and activating the sulfonic acid group of the cation exchange membrane.

Abstract: The present disclosure provides a transparent alumina-based plate, and a hot-pressing method to make the transparent alumina-based plate from platelet alumina. Alumina powder with a platelet morphology was hot-pressed to transparency with pre-load pressures of about 0-8 MPa, maximum temperatures of about 1750-1825° C., maximum pressures of about 2.5-80 MPa, and isothermal hold times of 1-7 hours. A novel alumina-based plate has been prepared, wherein the plate has a thickness of 2-5 mm, an in-line transmission of at least 60-75% for a light with a wavelength range of 645-2500 nm, an in-line transmission variance of <15% over the wavelength range of 645-2500 nm, and a relative density of 99.00-99.95%.

Abstract: Disclosed herein is a video decoding method including determining a zero-out width threshold and a zero-out height threshold for distinguishing between a transform coefficient coding region and a zero-out region of a current block according to a size of the current block, determining the transform coefficient coding region and the zero-out region of the current block according to the zero-out width threshold and the zero-out height threshold, acquiring transform coefficient information of the transform coefficient coding region from a bitstream and determining a level of a transform coefficient of the transform coefficient coding region according to the transform coefficient information, determining a level of a transform coefficient of the zero-out region as 0 without acquiring transform coefficient information, and reconstructing the current block by inversely transforming the transform coefficient of the current block.

Abstract: One embodiment of the present invention is directed to compositions and methods for enhancing attachment of soft tissues to a metal prosthetic device. In one embodiment a construct is provided comprising a metal implant having a porous metal region, wherein said porous region exhibits a nano-textured surface.

Abstract: Provided herein are nucleic acid-based nanoswitches that can detect specific nucleic acids and other analytes types by for example a simple gel electrophoresis readout. Binding of the target to the nanoswitches induces a conformation change from a linear, open conformation to a looped, closed conformation. These nanoswitches may be used in diagnostic assays such as nucleic acid-based diagnostic assays, to detect, measure and/or purify a variety of targets including low abundance targets.

Abstract: A new and distinct cultivar of citrus plant named ‘18A-9-39’, characterized by an easy-to-peel, nearly seedless, tangerine-type fruit with a very rich, sweet, and pleasant flavor; high sugar content in the fruit; vibrant orange fruit color; and good tolerance to HLB, especially when trees are supplemented with controlled release fertilizer (CRF) containing an enhanced micronutrient package.