Abstract: A tool holder assembly and method for intentionally inducing modulation in a machining process. The tool holder assembly is configured for mounting in a tool block on a machining apparatus and includes a tool holder body configured to be secured to the tool block of the machining apparatus, a tool holder mounted on the tool holder body and configured for securing a cutting tool thereto, and a device for imposing a superimposed modulation on the tool holder so as to move the cutting tool relative to the tool holder body and thereby relative to the tool. The tool holder assembly is useful in a process for producing chips having a desired shape and size, and particularly to a method of controllably producing nanocrystalline chips.
Type:
Grant
Filed:
May 3, 2006
Date of Patent:
September 15, 2009
Assignee:
Purdue Research Foundation
Inventors:
James B. Mann, Srinivasan Chandrasekar, Walter Dale Compton
Abstract: Polyacrylamide-based methods of fabricating surface-bound peptide and protein arrays, the arrays themselves, and a method of using the arrays to detect biomolecules and to measure their concentration, binding affinity, and kinetics are described. Peptides, proteins, fusion proteins, protein complexes, nucleic acids, and the like, are labeled with an acrylic moiety and attached to acrylic-functionalized glass surfaces through a copolymerization with acrylic monomer. The specific attachment of glutathione S-transferase-green fluorescent protein (GST-GFP) fusion protein was more than 7-fold greater than the nonspecific attachment of non-acrylic labeled GST-GFP. Surface-attached GST-GFP (0.32 ng/mm2) was detectable by direct measurement of green fluorescent protein fluorescence and this lower detection limit was reduced to 0.080 ng/mm2 using indirect antibody-based detection.
Type:
Grant
Filed:
December 16, 2005
Date of Patent:
September 15, 2009
Assignees:
Wisconsin Alumni Research Foundation, The University of Chicago
Inventors:
Shawn B. Brueggemeier, Stephen J. Kron, Sean P. Palecek, Laurie Parker, Stephen Brian Henry Kent
Abstract: The present invention relates to a novel process for sustainable, continuous production of hydrogen and carbon by catalytic dissociation or decomposition of hydrocarbons at elevated temperatures using in-situ generated carbon particles. Carbon particles are produced by decomposition of carbonaceous materials in response to an energy input. The energy input can be provided by at least one of a non-oxidative and oxidative means. The non-oxidative means of the energy input includes a high temperature source, or different types of plasma, such as, thermal, non-thermal, microwave, corona discharge, glow discharge, dielectric barrier discharge, or radiation sources, such as, electron beam, gamma, ultraviolet (UV). The oxidative means of the energy input includes oxygen, air, ozone, nitrous oxide (NO2) and other oxidizing agents.
Type:
Grant
Filed:
May 10, 2006
Date of Patent:
September 15, 2009
Assignee:
University of Central Florida Research Foundation, Inc.
Inventors:
Nazim Z. Muradov, Franklyn Smith, Ali Tabatabaieraissi
Abstract: Apparatus, methods and systems for a transmissive liquid crystal display including a plurality of pixel circuits, each pixel circuit including a reflective region and a transmissive region. The reflective region includes a polarization dependent reflector for reflecting ambient light. The reflective and transmissive regions include an initially homogeneously aligned liquid crystal layer sandwiched between a first and a second substrate. Each pixel further includes at least one first transparent electrode as the common electrode and at least one second transparent electrode as the pixel electrode both formed on one of the same first and second substrates, wherein substantial fringe fields with rich horizontal electric fields are generated in the liquid crystal layer when voltage is applied to the pixel electrode, making the liquid crystal molecules rotate mainly in the horizontal direction to achieve wide viewing angle.
Type:
Grant
Filed:
June 15, 2007
Date of Patent:
September 15, 2009
Assignees:
University of Central Florida Research Foundation, Inc., Chi Mei Optoelectronics Corp.
Abstract: The present invention provides a chiral ligand, represented by a formula or its enantiomer: X and X? can be independently O, NH, NR, NCOR or S; each of Z1-Z7 and Z1?-Z7? can be independently H, alkyl, aryl, substituted alkyl, substituted aryl, alkoxyl, aryloxyl, nitro, amide, aryloxide, halide, hydroxyl, carboxylate, heteroaryl, or a cyclic alkene, fused aryl, or cyclic ether group formed from any two adjacent Z groups or any two adjacent Z? groups; Y and Y? can be independently OH, OR, NH2, NHR, NR2, SH, PR2, OPR2, NHPR2, OP(OR)2, COOH, COOR, CONHR, or a linking group formed from Y and Y? groups together. Processes of preparing these ligands, catalysts that employ them and methods of using the catalysts are also provided.
Abstract: A method of differentiating embryonic stem cells into neural and motor cells is disclosed. In one embodiment, the invention comprises culturing a population of cells comprising a majority of cells that are characterized by an early rosette morphology and are Sox1?/Pax6+ in the presence of FGF2, FGF4, FGF8, FGF 9, or RA wherein the cells are characterized by an neural tube-like rosette morphology and are Pax6+/Sox1+.
Abstract: Disclosed is a stereo image matching method for re-creating 3-dimensional spatial information from a pair of 2-dimensional images. The conventional stereo image matching method generates much noise from a disparity value in the vertical direction, but the present invention uses disparity information of adjacent image lines as a constraint condition to eliminate the noise in the vertical direction, and compress the disparity by using a differential coding method to thereby increase a compression rate.
Abstract: The present invention provides a group B streptococcal (GBS) surface antigen, designated epsilon antigen, that is co-expressed with the delta antigen on a subset of serotype III GBS. Epsilon is expressed on more pathogenic Restriction Digest Pattern (RDP) III-3 GBS, but not on RDP types 1, 2, or 4. Accordingly, the present invention provides compositions and methods for detecting a group B streptococcus serotype III, RDP III-3 strain. Vaccines and methods of identifying agents which inhibit adhesion of a group B streptococcal cell to a host cell are also provided.
Type:
Grant
Filed:
August 19, 2005
Date of Patent:
September 15, 2009
Assignees:
St. Jude Children's Research Hospital, University of Florida, University of Utah Research Foundation
Inventors:
Linda Jeannine Brady, Kyle N. Seifert, Elisabeth E. Adderson, John F. Bohnsack
Abstract: Inositol derivatives in accordance with the present invention are effective in significantly enhancing the transportation of various therapeutic molecules across a biological membrane, which may include the plasma membrane, nuclear membrane or blood-brain barrier.
Abstract: According to the invention, there is provided seed and plants of the corn variety designated W701BC. This inbred variety yields multiple ears, and is ideal for production of baby corn. The invention further relates to the plants, seeds and tissue cultures of the variety W701BC, and to methods for producing a corn plant produced by crossing a corn plant of variety W701BC with itself or with another corn plant, such as a plant of another variety. The invention also relates to corn seeds and plants produced by crossing plants of variety W701BC with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety W701BC.
Type:
Grant
Filed:
July 26, 2006
Date of Patent:
September 15, 2009
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
James G. Coors, Dustin T. Eilert, Patrick J. Flannery
Abstract: A taxane having a cyclopentyl ester substituent at C10, a keto substituent at C9, a hydroxy substituent at C2, a 2-thienyl substituent at C3? and an isopropoxycarbamate substituent at C3?.
Type:
Grant
Filed:
February 14, 2005
Date of Patent:
September 15, 2009
Assignee:
Florida State University Research Foundation, Inc.
Abstract: Methods, systems and processes for providing efficient image reconstruction using local cone beam tomography which provide a reduced level of artifacts without suppressing the strength of the useful features; and in a dynamic case provide reconstruction of objects that are undergoing a change during the scan. An embodiment provides a method of reconstructing an image from cone beam data provided by at least one detector. The method includes collecting CB projection data of an object, storing the CB projection data in a memory; and reconstructing the image from the local CB projection data. In the reconstructing step, a combination of derivatives of the CB projection data that will result in suppressing the artifacts are found. The combination of derivatives includes collecting cone beam data that represents a collection of integrals that represent the object.
Type:
Grant
Filed:
October 13, 2006
Date of Patent:
September 15, 2009
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: Systems, configurations and methods of using an ultrafast, self-starting, mode-locked laser are provided. The systems, devices and methods of using stable, self-starting mode-locked lasers, can be compact, use fewer optical elements and have energies sufficient for most micro-processing and micro-structuring applications. The large spectral bandwidth of ultra-short (femtosecond) laser pulses can be used in laser sensing applications, micro-machining, time-resolved experiments, where short-lived transient species can be observed in biological or chemical reactions. Terahertz radiation can be generated using ultrashort pulses and used for imaging applications.
Type:
Grant
Filed:
May 17, 2005
Date of Patent:
September 15, 2009
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: The invention provides recombinant viruses comprising heterologous envelope proteins capable of mediating entry of the recombinant viruses into host cells. In one embodiment, a recombinant virus of the invention is a member of the Paramyx-ovirzdae family (e.g., a respiratory syncytial virus), and the heterologous envelope protein includes the ectodomain of a baculovirus envelope protein (e.g., the GP64 protein). In some cases, the heterologous envelope protein is provided in addition to homologous envelope proteins) which may or may not be functional. The heterologous protein can provide the recombinant virus with enhanced stability (e.g., at 4° C., 22° C., or 37° C.), and allows production of high-titer virus stocks. The heterologous protein can also impart temperature sensitivity to the replication of the recombinant virus. In addition, the recombinant virus can be designed to be infectious but incapable of spreading between host cells by providing the heterologous protein by complementation in trans.
Type:
Grant
Filed:
December 10, 2004
Date of Patent:
September 15, 2009
Assignee:
The UAB Research Foundation
Inventors:
Antonius G. P. Oomens, Gail W. Wertz, Alexander George Megaw
Abstract: The present invention provides a wound dressing that includes a patterned gradient of immobilized growth factor molecules that promote directed migration of cells during dermal wound healing. Growth factor is immobilized on a support substrate to present a gradient pattern of increasing growth factor concentration to migrating cells. Methods of promoting wound healing using the patterned gradient wound dressing and fabrication methods of same are also provided.
Type:
Application
Filed:
March 4, 2008
Publication date:
September 10, 2009
Applicant:
Wisconsin Alumni Research Foundation
Inventors:
Kristyn Simcha Masters, Tracy Jane Stefonek
Abstract: The growing surface of a material such as InGaN is exposed to a small diameter laser beam that is directed to controlled locations, such as by scanning mirrors. Material characteristics may be modified at the points of exposure. In one embodiment, mole fraction of selected material is reduced where laser exposure takes place. In one embodiment, the material is grown in a MBE or CVD chamber.
Abstract: Agglomerate tile structures and ceiling tile structures: The agglomerate tile structures can be of a single layer having an intermixed granular base medium comprised of one or more subcomponent materials (e.g., powdered, crushed, chips, and/or other broken pieces of varying sized particles, of quartz, granite, limestone, marble, glass, ceramic, semiprecious stones, etc.), plus a binder material and a PCM component; or the agglomerate tile structures can be of multiple layers, such as having an outer wear-layer substantially absent of PCM component—this outer wear-layer being bonded or otherwise incorporated with a second layer comprised of a binder material and a PCM component, substantially absent of the granular base medium.
Type:
Application
Filed:
February 6, 2009
Publication date:
September 10, 2009
Applicant:
Colorado State University Research Foundation (CSURF)
Abstract: In one embodiment, a system and method for designing an optical surface pertain to constructing a matrix of radial basis functions, each column of the matrix corresponding to a radial basis function, selecting an initial surface to be used as a starting point, selecting initial weights for the radial basis functions, generating an initialized optical surface based upon the selected initial surface and initial weights, and optimizing the initialized optical surface to minimize an error function.
Type:
Application
Filed:
November 10, 2008
Publication date:
September 10, 2009
Applicant:
University of Central Florida Research Foundation, Inc.
Abstract: A new and distinct variety of nectarine tree, denominated ‘UFRoyal’, has a low winter chilling requirement estimated at 250 chill units (cu). The tree is medium size and moderately vigorous with a semi-spreading growth habit. It produces showy, pink flowers and small reniform leaf glands. Trees of ‘UFRoyal’ are self-fertile and regularly bear heavy annual crops of early season fruit that are large for its ripening season. Fruit are uniformly firm and yellow with non-melting flesh which are clingstone. Fruit are oval, and uniform with substantially symmetrical shape, and have an attractive 90 to 100% bright red skin. The fruit of ‘UFRoyal’ ripen about 1 week before ‘UFQueen’ nectarine in early May at Gainesville, Fla.