Abstract: Materials and methods for preparing the surface of dentin, enamel, or other natural or industrial substrates containing or capable of binding metallic ions, for adhesion of composite materials or resins, are disclosed. Preferably, the substrate is treated with an aqueous solution comprising at least one acid, acidic salt, or chelating or sequestering agent.
Type:
Grant
Filed:
June 15, 1992
Date of Patent:
December 14, 1993
Assignee:
American Dental Association Health Foundation
Abstract: A method for treating Candida infections of surfaces and cavities of dentures, the oral and vaginal cavities is disclosed. The method includes contacting an antifungal formulation onto the surface or cavity which is infected with the Candida fungus. The antifungal formulation includes a humectant in a concentration from about 20% to about 80%, lytic activating agents including inorganic monovalent anions and detergents. The antifungal formulation is contacted to the infected surface or cavity by suitable carrier or dispenser. The method is preferably directed towards the treatment of denture stomatitis in the oral cavity. The method preferably includes forming a replica of the denture surface using a suitable fungal growth medium to determine the location and, then, contacting the infected denture surface and surface of the oral cavity with the antifungal formulation.
Type:
Grant
Filed:
August 6, 1992
Date of Patent:
December 14, 1993
Assignee:
The Research Foundation of State University of New York
Inventors:
Jerry P. Pollock, Robert Renner, Ralph P. Santarpia, III
Abstract: An improved method for detecting an incipient failure in a multiphase electric motor includes the following steps: periodically measuring or continuously monitoring voltage and current values at each input to the motor; determining negative sequence voltage and current values for each periodic measured input voltage and current value; calculating an effective negative sequence impedance phasor value angle from each of the determined negative sequence voltages and current values; and comparing the calculated negative sequence impedance phasor angles and/or real and imaginary components over a plurality of periodic measurements to detect a change therein, which change is indicative of an incipient failure mode.
Abstract: The invention includes a means and method for transmitting and receiving broadband, unipolar, ultrasonic pulses for ultrasonic inspection. The method comprises generating a generally unipolar ultrasonic stress pulse from a low impedance voltage pulse transmitter along a low impedance electrical pathway to an ultrasonic transducer, and receiving the reflected echo of the pulse by the transducer, converting it to a voltage signal, and passing it through a high impedance electrical pathway to an output. The means utilizes electrical components according to the method. The means and method allow a single transducer to be used in a pulse/echo mode, and facilitates alternatingly transmitting and receiving the broadband, unipolar, ultrasonic pulses.
Type:
Grant
Filed:
February 8, 1990
Date of Patent:
December 14, 1993
Assignee:
Iowa State University Research Foundation, Inc.
Abstract: A method and apparatus for determining the characteristics of materials, particularly of semiconductors, semiconductor heterostructures and semiconductor interfaces by the use of photoreflectance, in which monochromatic light and modulated light beam reflected from the sample is detected to produce a d.c. signal and an a.c. signal, whereby the d.c. signal is applied to one input of a computer and the a.c. signal is used with another input of the computer which controls the light intensity of the monochromatic light impinging on the sample to maintain the d.c. signal substantially constant. A stepping motor is preferably utilized for varying the light intensity of the monochromatic light which is controlled by a computer to re-establish rapidly a predetermined d.c. signal established during normalization procedures when the light intensity of the monochromatic light changes, especially during change of its wavelength.
Abstract: An apparatus for lifting and stabilizing a structural slab overlying the ground includes a base attached to the upper surface of the slab, at least one hydraulic cylinder vertically supported from the base and a slip clamp assembly attached to the piston rod extending from the cylinder. Piling segments are sequentially passed downward through the slip clamp and through coaxial holes in the base and in the slab, and are driven into the ground by the hydraulic cylinder to form a support column under the slab.
Type:
Grant
Filed:
February 2, 1993
Date of Patent:
December 14, 1993
Assignee:
Power Lift Foundation Repair
Inventors:
William B. Bolin, William B. McCown, Jr.
Abstract: A method of making a novel sugar-based polymer is disclosed. A sugar and an organic acid derivative having at least two carboxylate functionalities are mixed in a substantially non-aqueous organic solvent with a hydrolytic enzyme and, thereafter, the resulting mixture is agitated for a time sufficient to allow for the polymerization of the sugar. The resulting sugar-based polymer has sugar incorporated in the polymer backbone.
Type:
Grant
Filed:
July 22, 1992
Date of Patent:
December 14, 1993
Assignee:
University of Iowa Research Foundation
Inventors:
Jonathan S. Dordick, David G. Rethwisch, Damodar R. Patil
Abstract: A microwave sweep oscillator is used to apply an AC signal cross a scanning tunneling microscope and the current or voltage passing between the electrodes is measured by a microwave spectrum/network analyzeThis invention was made with support from the National Science Foundation, United States Government, under Grant No. CHE-9158375. The government has rights in this invention.
Type:
Grant
Filed:
July 17, 1992
Date of Patent:
December 7, 1993
Assignees:
The Penn State Research Foundation, Penn State Research Foundation and Biotechnology Research
Abstract: A method for interactively entraining a patient's heart rate to a target rate or frequency includes the steps of determining the patient's heart rate through a heart rate monitor and exposing the patient to music having a tempo within approximately one (1) beat of the heart rate. The heart rate is again determined, and if it has changed the tempo of the music is likewise changed in order to be within approximately one (1) beat of the heart rate. The process is continued until the target rate is reached. Vibrational bass tones can be added to enhance the entrainment. Similar methods can be used to entrain respiration rate and fundamental brain wave frequencies, in the latter case using continuous tones of music having repetition frequencies within the entrainment range.
Abstract: A controller for an inchworm type linear transducer is constructed so as to be extremely low noise and to permit very fine positioning. This is done by storing the desired output waveforms in digital form in an EEPROM memory array and then counting through the address locations of the memory array to re-create the desired waveform. An analog amplifier is used to actually drive the piezoelectric elements in the transducer.
Type:
Grant
Filed:
September 29, 1992
Date of Patent:
December 7, 1993
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Robert J. Hamers, Xiang Chen, Marcus T. McEllistrem
Abstract: This invention involves the use of amorphous calcium compounds such as: amorphous calcium phosphate (ACP), amorphous calcium phosphate fluoride (ACPF) and amorphous calcium carbonate phosphate (ACCP) for use in remineralizing teeth. These amorphous compounds or solutions which form the amorphous compounds, when applied either onto or into dental tissue prevent and/or repair dental weaknesses such as dental caries, exposed roots and dentin sensitivity. The compounds have the highest solubilities, fastest formation rates and fastest conversion rates (to apatite) among all the calcium phosphorate under physiological conditions. Moreover, in the presence to fluoride the amorphous compound convert rapidly to fluoride containing apatite.
Type:
Grant
Filed:
July 1, 1991
Date of Patent:
December 7, 1993
Assignee:
American Dental Association Health Foundation
Abstract: An ion trap mass spectrometer includes an ion trap region separated from an electron multiplier region by a baffle, and separate turbomolecular pumps for pumping each region to a different pressure level. The ion trap region can therefore be pumped to a higher pressure level than ca be used for the electron multiplier region, and the result and increase in pressure of damping gas in the ion trap region increases the sensitivity of the device.
Abstract: Bioactive cocaine analogs of the general formulae: ##STR1## are provided wherein X' is H or (C.sub.1 -C.sub.5)alkyl, X is H, halo, alkyl, alkoxy, perfluoroalkyl, nitro, alkoxycarbonyl, dialkoxyphosphonyl, acyl, perfluoroacyl, azido (substituted)silyl or (substituted)thio, and Y is H, halo, nitro, amino or (substituted)amino, alkoxycarbonyl, carboxy, alkyl or alkoxy; and the pharmaceutically acceptable salts thereof.
Type:
Grant
Filed:
September 22, 1992
Date of Patent:
December 7, 1993
Assignee:
Mayo Foundation for Medical Education and Research
Abstract: A mounting mechanism for a double crystal monochromator or the like has a parallelogram based mounting mechanism in which two of the vertices of the parallelogram are fixed in position, and two vertices are free to translate back and forth in a straight line parallel to the fixed base of the parallelogram. One diffractor is mounting for pivoting at one of the fixed vertices, and the second diffractor is mounted for pivoting at an adjacent movable vertex. The surfaces of the diffractors are maintained parallel as the angle of the diffractors with respect to input and output beams to the monochromator is changed to change the wavelength being passed. The diffractor mounted at the fixed pivot may be connected to a large diameter wheel which in turn is connected by a band to a smaller diameter wheel mounted for rotation at the other fixed vertex of the parallelogram, with a pivotable arm connected to the smaller wheel to rotate therewith.
Abstract: The presence or absence of a nucleic acid sequence of an isolate of HTLVI and/or HTLVII in a sample containing one or more nucleic acids and suspected of containing such sequence can be detected by amplifying the sequence using primers to form extension products as templates and detecting the amplified product if it is present. This may be accomplished by adding a labeled hybridization probe to the amplified product, either free in solution or after immobilization on a solid support.
Type:
Grant
Filed:
August 28, 1991
Date of Patent:
December 7, 1993
Assignees:
Hoffmann-La Roche Inc., Research Foundation of State University of New York
Inventors:
John J. Sninsky, Shirley Y. Kwok, Bernard Poiesz
Abstract: A catalyst for the steam reforming of hydrocarbons characterized in that 0.1-2 wt. % of ruthenium is carried on a carrier which comprises 5-40 wt. % of ceria or rare element oxides containing ceria as the main ingredient and 60-95 wt. % of alumina, and that an atomic ratio of cerium to ruthenium (Ce/Ru) in the catalyst is in the range of from more than 10 to 200.
Type:
Grant
Filed:
March 2, 1992
Date of Patent:
December 7, 1993
Assignees:
Nippon Oil Co., Ltd., Petroleum Energy Center Foundation
Abstract: Fluoropolymers modified by radio frequency glow discharge in the presence of vapor/gas plasma provides for permanent and controlled substitution of hydrogen and oxygen functionality for fluorine. The oxygen-containing sites of the modified fluoropolymer are highly reactive, enabling the material to be readily refunctionalized by the introduction of a new atom, functionality or macromolecular unit, such as organosilane, alkali metal or reactive fluorescent compound.
Type:
Grant
Filed:
May 11, 1990
Date of Patent:
November 30, 1993
Assignee:
The Research Foundation of State University of New York
Inventors:
Joseph A. Gardella, Jr., Terrence G. Vargo
Abstract: Novel non-elastomeric biomedical adhesive compositions for calcified tissues, are described. The compositions are characterized by a network structure which is obtained by the reaction of a polyisocyanate having at least two isocyanate groups with at least one polyol which possesses surface wetting properties with the participation of compounds selected from calcium and phosphorus, optional in the presence of a catalyst. The polyisocyanate is selected from aliphatic, alicyclic and aromatic compounds and preferred amounts are in the range of 20% to 80% by weight of the total amount of reactants. The polyol is selected from polyalkylene ether glycols and polyester glycols containing between 25 to 75 carbon atoms and preferred amounts are in the range of 10% to 80% by weight of the total amount of reactants. The adhesive compositions were found to produce a fast bonding of the calcified tissues, with a joint strength of above 0.5 N/sq.mm.
Type:
Grant
Filed:
June 27, 1991
Date of Patent:
November 30, 1993
Assignees:
Technion Research & Dev't Foundation, Ltd., GBF Gesellschaft fur Biotechnologische Forschung
Inventors:
Dov Katz, Esther Brandeis, Joachim Klein
Abstract: Genes encoding insect-specific paralytic neurotoxins, particularly those of insect-parasitic mites, including Pyemotes, are described. Recombinant DNA molecules in which the neurotoxin coding sequences are placed under the control of heterologous promoters are also described. Such molecules are useful for the development of biological insect control agents which produce insect-toxic levels of the neurotoxin. Specifically described are genetically altered baculoviruses which produce insect-specific paralytic neurotoxins and which display improved toxic effect on insects. Insect-toxic compositions are also provided. Methods of insect control using these neurotoxin genes, methods for production of neurotoxins in cells, and methods of production of insect control agents are described.
Type:
Grant
Filed:
October 4, 1990
Date of Patent:
November 30, 1993
Assignee:
University of Georgia Research Foundation, Inc.
Abstract: A phototherapy method wherein sequences of various substantially isolated electromagnetic energy patterns are directed into an observer's eyes in order to determine to which such pattern the observer is most responsive in terms of being induced towards a state of homeostasis. Subsequent irradiation of the observer's eyes with such pattern will bring about therapeutic effects in the observer.