Patents Assigned to Foundation
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Patent number: 5173976Abstract: A mattress cover/fitted bed sheet which consists of a substantially rectangular blank of textile material with opposed sides and opposed ends. A pair of generally triangular pieces are cut out of the opposed sides adjacent the ends. Each of the triangular cut outs has a pair of opposed sides, an apex directed inwardly on the textile material and a base coincident with one of the sides of the textile material. The sides of the triangular cut outs are joined to form a biased side seam such that, when placed on a mattress, textile material is drawn under the end of the mattress.Type: GrantFiled: April 23, 1992Date of Patent: December 29, 1992Assignee: Enerbase Foundations Ltd.Inventor: Gisele B. Jubinville
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Patent number: 5175267Abstract: A method of preparation of 2',3'-dideoxy and 2',3'-dideoxy-2',3'-didehydronucleosides that includes the step of condensing a 1-O-activated-2-(aromatic or aliphatic)-selenenyl-5-O-protected ribose with a protected heterocyclic base in the presence of trimethylsilyl triflate or a Lewis acid to form a .beta.-anomeric nucleoside in high yield.Type: GrantFiled: March 2, 1990Date of Patent: December 29, 1992Assignee: University of Georgia Research Foundation, Inc.Inventor: Chung K. Chu
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Patent number: 5173219Abstract: An improved, rapid method for preparing substantially spherical multilamellar liposomes of a defined and adjustable size within the range of 2 to 100 micrometers, suitable for encapsulation and targeting of drugs.Type: GrantFiled: April 25, 1990Date of Patent: December 22, 1992Assignee: Research Development FoundationInventor: Sinil Kim
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Patent number: 5173354Abstract: A continuous thin film metal coated ceramic substrate is provided by employing intimate mixtures of transition element metal and element different from the transition element metal which is from the same group of the Periodic Table as the metallic or semimetallic atom of the ceramic of the substrate.Type: GrantFiled: December 13, 1990Date of Patent: December 22, 1992Assignee: Cornell Research Foundation, Inc.Inventor: Rishi Raj
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Patent number: 5172951Abstract: A robotic grasping manipulator includes a support base, a fixed elongate index finger which extends forwardly a certain distance from the base and then curves upwardly to terminate in a tip, and a two-degree of freedom elongate thumb pivotally attached at a proximal end to the base to extend generally forwardly therefrom to terminate in a distal end which may be moved vertically and laterally with respect to the fixed finger to thereby enable holding objects between the finger and thumb. Also included is a moveable elongate finger pivotally attached at a proximal end to the base to extend forwardly a certain distance and then upwardly, generally alongside the index finger, to terminate in a distal end. The distal end may be moved laterally away from and toward the index finger to thereby enable holding objects between the two fingers.Type: GrantFiled: August 6, 1990Date of Patent: December 22, 1992Assignee: University of Utah Research FoundationInventors: Stephen C. Jacobsen, Fraser Smith
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Patent number: 5173294Abstract: A plasmid which contains a genetic code for an immunogenic portion which is conserved in many strains of nontypable Haemophilus influenzae and the bacterium containing this plasmid is disclosed. The immunogenic portion is preferably an epitope on an outer membrane protein of H. influenzae. A monoclonal antibody to the immunogenic portion and the hybridoma which will produce the monoclonal antibody is also included. The invention further includes a DNA probe constructed to correspond to the nucleic acids which code for the immunogenic portion. This probe may be labelled with a radioactive marker and may be used as a diagnostic tool to assay various clinical samples for the presence of H. influenzae.Type: GrantFiled: October 8, 1987Date of Patent: December 22, 1992Assignee: Research Foundation of State University of New YorkInventors: Timothy F. Murphy, Michael A. Apicella
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Patent number: 5173419Abstract: Two chitinases from Trichoderma harzianum P1 (ATCC 74058) show chitin-containing-fungus- and insect-inhibiting activity. The first is an endochitinase having a molecular weight of 36 kDa and an isoelectric point of 5.3.+-.0.2. The second is an exochitinase having a molecular weight of 36 kDa an an isoelectric point of 4.4.+-.0.2. The chitinases can be applied in contact with chitin-containing fungus or insect as an inhibitor thereof. The chitinases can be applied to plants or to soil around plants which need production from a chitinase-containing pest. The chitinases can also be used to isolate genes coding for them which can be inserted into a genome of a plant needing protection from a chitinase-containing pest or into the genome of a microorganism to provide transgenic microorganism useful to produce enzyme or as a biocontrol agent.Type: GrantFiled: June 17, 1991Date of Patent: December 22, 1992Assignee: Cornell Research Foundation, Inc.Inventors: Gary E. Harman, Roxanne M. Broadway, Arne Tronsmo, Matteo Lorito
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Patent number: 5172977Abstract: An isobaric mercury dilatometer for measurements of volume changes of solid specimens under a constant hydrostatic pressure either as a function of time or as a function of temperature. It includes structures for minimizing entrapment of air in the system, accurate computerized measurements in spite of the presence of some air. A two-piece stainless steel container is equipped with a horizontally situated volume-measuring stem, a filling device, an air vent and a temperature sensor. The specimen to be studied is placed in the container which is subsequently filled with mercury up to the stem. The volume changes of the specimen is reflected to the capacitance signals of an aluminum sleeve around the stem, while the temperature sensor generates temperature-related electronic signals. Both signals are received by a computer which translates them into volume and temperature data.Type: GrantFiled: January 3, 1992Date of Patent: December 22, 1992Assignee: Iowa State University Research Foundation, Inc.Inventors: Bekir V. Enustun, Turgut Demirel
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Patent number: 5173403Abstract: A thermostable, very acidic protease, which has been named thermopsin, was purified to homogeneity from the culture medium of Sulfolobus acidocaldarius by a five-step procedure including column chromatographies on DEAE-Sepharose CL-6B, phenyl-Sepharose CL-4B, Sephadex G-100, MonoQ (FPLC), and gel filtration (HPLC). The enzyme is a single polypeptide chain having proteolytic activity over pH range 0 to 11 at temperatures between 0.degree. and 100.degree. C., with maximal activity at approximately pH 2 and 90.degree. C. Antibodies directed against thermopsin have been prepared. Through studies using various aspartic protease inhibitors, thiol and metalloprotease inhibitors, and serine protease inhibitors, it was determined that, although similar to some aspartic proteases, the active site of thermopsin is clearly not identical to that of other aspartic proteases.Type: GrantFiled: January 19, 1990Date of Patent: December 22, 1992Assignee: Oklahoma Medical Research FoundationInventors: Jordan J. N. Tang, Xin-Li Lin
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Patent number: 5172587Abstract: A device for testing the loading of a test pile extending downwardly into the ground. The device includes a reaction pile axially disposed inside the test pile and a reference pile axially disposed inside the reaction pile. The reaction pile extends further into the ground than the test pile and the reference pile extends further into the ground than the reaction pile. A loading device simultaneously exerts a downward force on the test pile and an upward reaction force on the reaction pile such that the test pile moves downwardly, and a laser distance measurement system, attached to the test pile and extending axially therewith, also moves downwardly. The laser distance measurement system resides in a test chamber defined by a shroud circumscribing the test device and secured to the top of the test pile so as to move downwardly therewith.Type: GrantFiled: March 13, 1991Date of Patent: December 22, 1992Assignee: Arctic Foundations, Inc.Inventor: Erwin L. Long
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Patent number: 5171217Abstract: A method and composition for delivering a drug to an affected intramural site for sustained release in conjunction with or following balloon catheter procedures, such as angioplasty. The drug, carried by microparticles of a physiologically-compatible, biodegradable polymer is injected under directed pressure into the wall of a body vessel in the region of the affected site.Type: GrantFiled: February 28, 1991Date of Patent: December 15, 1992Assignee: Indiana University FoundationInventors: Keith L. March, David R. Hathaway, Robert L. Wilensky
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Patent number: 5172382Abstract: Polarization self-modulation of a laser produces high-frequency optical modulation without the use of high-speed electronics. This is accomplished by inserting into a laser cavity a polarization converter, which rotates the polarization of the laser light periodically as the light passes through the converter as it circulates in the cavity. The frequency of the modulation is determined by the cavity length. In one configuration, a quarter-wave retardation plate is used as the intracavity polarization converter in a Fabry-Perot laser. In a second embodiment, the converter is an electro-optic crystal which acts as an electronically-controllable half-wave retardation plate.Type: GrantFiled: February 5, 1991Date of Patent: December 15, 1992Assignee: Cornell Research Foundation, Inc.Inventors: Wei-Hung Loh, Alfred T. Schremer, Yukihiro Ozeki, Chung L. Tang
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Patent number: 5172193Abstract: An apparatus for predicting milk coagulum cut-time in a cheese making process includes a light source, a sensor or detector for sensing diffuse reflectance of light from said milk and a controller for analyzing the diffuse reflectance and accurately predicting the cut-time to significantly enhance overall yield. More specifically, the apparatus includes an optical probe which may be suspended over the milk or attached to a wall of a fermentation vessel in which the milk is contained. A method for predicting milk coagulum cut-time includes the steps of (a) directing light from a light source toward milk undergoing enzymatic hydrolysis; (b) sensing diffuse reflectance of that light from the milk; (c) analyzing the sensed diffuse reflectance profile and (d) signaling the cut-time. The sensing occurs at between 400 to 6000 nm. Specific mathematical formulae for the analyzing steps are also disclosed.Type: GrantFiled: February 15, 1990Date of Patent: December 15, 1992Assignee: University of Kentucky Research FoundationInventors: Frederick A. Payne, Clair L. Hicks
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Patent number: 5171841Abstract: The invention provides a purified protein substantially free of other human proteins, having an amino acid sequence sufficiently duplicative of the sequence: ##STR1## such that the protein is capable of selectively suppressing the immune function of T-helper cells.Type: GrantFiled: April 9, 1990Date of Patent: December 15, 1992Assignee: Cornell Research Foundation, Inc.Inventor: Jeffrey C. Laurence
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Patent number: 5171849Abstract: There is disclosed a process for preparing carboranyl uridine nucleoside compounds and their diethyl ether adducts, which exhibit a tenfold increase in boron content over prior art boron containing nucleoside compounds. Said carboranyl uridine nucleoside compounds exhibit enhanced lipophilicity and hydrophilic properties adequate to enable solvation in aqueous media for subsequent incorporation of said compounds in methods for boron neutron capture therapy in mammalian tumor cells.Type: GrantFiled: April 19, 1991Date of Patent: December 15, 1992Assignee: The Ohio State University Research FoundationInventors: Albert H. Soloway, Rolf F. Barth, Abul K. Anisuzzaman, Fazlul Alam, Werner Tjarks
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Patent number: 5171885Abstract: The pure isomers L-buthionine-S-sulfoximine and L-buthionine-R-sulfoximine are provided. The L-S-isomer has utility, for example, in causing the depletion of glutathione, a major protectant molecule in tumors and certain parasites. The L-R-isomer has utility as a compound decreasing further uptake and thus effect of the L-S-isomer and for causing glutathione depletion specific to the kidney. The isolation of pure isomers from L-buthionine-SR-sulfoximine enables treatment at lower dosages without cross effects.The pure L-buthionine-S-sulfoximine isomer is obtained from L-buthionine-SR-sulfoximine by recrystallization preferably by forming a solution of L-buthionine-SR-sulfoximine in water at a concentration of 0.Type: GrantFiled: June 19, 1991Date of Patent: December 15, 1992Assignee: Cornell Research Foundation, Inc.Inventor: Owen W. Griffith
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Patent number: 5171677Abstract: A recombinant Marek's disease virus which comprises a Marek's disease virus genom and a DNA fragment incorporated therein, said DNA fragment being constructed by incorporating a promoter derived from an animal cell or an animal virus and a structural gene coding for an exogenous protein into a gene fragment derived from a Marek's disease virus, a process for preparing the same which comprises preparing a gene fragment wherein a structural gene coding for an exogenous gene is linked to the downstream of a promoter derived from an animal cell or an animal virus, incorporating said gene fragment into a BamHI - H fragment of a gene of a Marek's disease virus type I, and incorporating said fragment into a Marek's disease virus type I genome, and a multivalent live vaccine for birds comprising the same.Type: GrantFiled: September 8, 1989Date of Patent: December 15, 1992Assignee: Juridical Foundation The Chemo-Sero-Therapeutic Research InstituteInventors: Masashi Sakaguchi, Hiroaki Maeda, Michitaka Yamamoto, Junichi Miyazaki
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Image compression method and apparatus employing distortion adaptive tree search vector quantization
Patent number: 5172228Abstract: A variable rate vector quantization method employs a tree structured codebook. The level of the codebook from which codevectors are selected is determined by a threshold. The threshold varies according to the fullness of a buffer which stores vector quantized data to be transmitted.Type: GrantFiled: November 19, 1991Date of Patent: December 15, 1992Assignee: Utah State University FoundationInventor: Paul D. Israelsen -
Patent number: 5170730Abstract: A mobile seed planter includes a plurality of planting assemblies with each of the assemblies being selectively activatable for planting seeds and including structure defining a seed cavity for receiving seeds to be planted. A discharging structure in communication with the seed cavities receives seeds therefrom for discharging seeds onto the ground. A control assembly, operably coupling the planting assemblies, includes structure for selectively activating one of the planting assemblies and for preventing activation of the other of the planting assemblies thereby limiting the discharging of seeds onto the ground to only one of the planting assemblies at a time.Type: GrantFiled: April 22, 1991Date of Patent: December 15, 1992Assignee: Kansas State University Research FoundationInventor: Clarence Swallow
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Patent number: 5170963Abstract: The present invention provides a vertical takeoff and landing aircraft vehicle in which a ducted fan with upwardly directed inlet discharges air generally horizontally across a segmented circular wing. Said wing segments are individually controllable in pitch and each includes a spoiler and split flaps to increase effectiveness and sensitivity in lifting and controlling the aircraft. Directional stability and thrust for horizontal movement is provided by controls directing different proportions of total airflow to the various segments around the aircraft and varying the direction of said airflow both radially and vertically. Power failure protection is provided by means for maintaining free rotation of the fan until needed to provide lift at touchdown.Type: GrantFiled: September 24, 1991Date of Patent: December 15, 1992Assignee: August H. Beck Foundation CompanyInventor: August H. Beck, Jr.
